PRLR Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description prolactin receptor|This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 5618)
External Link https://ncbi.nlm.nih.gov/gene/5618
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Genes

499 genes differentially expressed following the PRLR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0174196
PHACTR2 phosphatase and actin regulator 2 0.0167294
TM4SF1 transmembrane 4 L six family member 1 0.0149517
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0140114
NBPF10 neuroblastoma breakpoint family, member 10 0.0137567
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.0128355
PCNA proliferating cell nuclear antigen 0.0127876
PCLAF PCNA clamp associated factor 0.0124929
F13A1 coagulation factor XIII, A1 polypeptide 0.012036
ANPEP alanyl (membrane) aminopeptidase 0.0118207
CADM1 cell adhesion molecule 1 0.0116924
TYMS thymidylate synthetase 0.0115782
GOLGA8A golgin A8 family, member A 0.0115329
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0111359
SEPP1 selenoprotein P, plasma, 1 0.0110968
PDGFC platelet derived growth factor C 0.0110428
SCARB2 scavenger receptor class B, member 2 0.0107918
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.0105921
HHEX hematopoietically expressed homeobox 0.0105636
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0105487
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.0103494
ANKRD10 ankyrin repeat domain 10 0.0102737
ADAM9 ADAM metallopeptidase domain 9 0.0102319
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0100624
IQGAP2 IQ motif containing GTPase activating protein 2 0.0100246
SPTSSA serine palmitoyltransferase, small subunit A 0.010018
ABAT 4-aminobutyrate aminotransferase 0.00995873
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00994895
KIF14 kinesin family member 14 0.00993161
PDE8A phosphodiesterase 8A 0.00992371
CD163 CD163 molecule 0.00990933
FZD6 frizzled class receptor 6 0.00979927
KIF5B kinesin family member 5B 0.00974193
ADGRL2 adhesion G protein-coupled receptor L2 0.00973079
FNDC3A fibronectin type III domain containing 3A 0.00964889
TPBG trophoblast glycoprotein 0.00963173
TASOR2 transcription activation suppressor family member 2 0.00947698
ALB albumin 0.00942404
CPVL carboxypeptidase, vitellogenic-like 0.00933878
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00928909
ITM2A integral membrane protein 2A 0.00928061
SLC35G2 solute carrier family 35, member G2 0.0092413
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00922527
PRC1 protein regulator of cytokinesis 1 0.0092215
MAGEA3 melanoma antigen family A3 0.00921632
ARMT1 acidic residue methyltransferase 1 0.00920373
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 0.00908032
POSTN periostin, osteoblast specific factor 0.00905902
TRIO trio Rho guanine nucleotide exchange factor 0.00904147
SLC38A1 solute carrier family 38, member 1 0.00903269
ITPRID2 ITPR interacting domain containing 2 0.00902305
GCLM glutamate-cysteine ligase, modifier subunit 0.00899105
SPRY2 sprouty homolog 2 (Drosophila) 0.00888676
SDC2 syndecan 2 0.00888311
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00884545
ENOPH1 enolase-phosphatase 1 0.00881789
CCDC92 coiled-coil domain containing 92 0.0088128
DLK1 delta-like 1 homolog (Drosophila) 0.00879641
DPYD dihydropyrimidine dehydrogenase 0.00876594
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00872755
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00872556
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00871891
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.00869113
ZNF148 zinc finger protein 148 0.00866531
CHGB chromogranin B 0.00864998
RUFY3 RUN and FYVE domain containing 3 0.00853908
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00849341
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00848671
CHI3L2 chitinase 3-like 2 0.00841566
MRPS30 mitochondrial ribosomal protein S30 0.00839318
MGP matrix Gla protein 0.00838708
CEP55 centrosomal protein 55kDa 0.00838176
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.00834179
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00833878
DIO2 deiodinase, iodothyronine, type II 0.00831994
NELL1 NEL-like 1 (chicken) 0.00830562
MTF2 metal response element binding transcription factor 2 0.00830349
CHD9 chromodomain helicase DNA binding protein 9 0.00829658
CCL2 chemokine (C-C motif) ligand 2 0.00825725
ACSL3 acyl-CoA synthetase long-chain family member 3 0.00821621
RHOBTB3 Rho-related BTB domain containing 3 0.00818853
PCDH9 protocadherin 9 0.0081823
GNAS GNAS complex locus 0.00815176
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00803818
CD14 CD14 molecule 0.0079787
LRP12 low density lipoprotein receptor-related protein 12 0.00793171
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.00792209
ZNF281 zinc finger protein 281 0.00790039
LIMCH1 LIM and calponin homology domains 1 0.00789132
PTCH1 patched 1 0.00787895
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 0.00783557
IPO5 importin 5 0.00776969
NFASC neurofascin 0.00775601
ZIC1 Zic family member 1 0.00774832
LONP2 lon peptidase 2, peroxisomal 0.0077456
MACF1 microtubule-actin crosslinking factor 1 0.00774271
DOCK9 dedicator of cytokinesis 9 0.00765247
KMT5B lysine methyltransferase 5B 0.0076461
NCK1 NCK adaptor protein 1 0.00764081
SCG5 secretogranin V 0.00761669
MAPK6 mitogen-activated protein kinase 6 0.00761615
FASTKD3 FAST kinase domains 3 0.00758757
ADGRL3 adhesion G protein-coupled receptor L3 0.0075612
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0075505
SOX11 SRY (sex determining region Y)-box 11 0.00752474
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00750724
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0075068
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00750254
SOCS5 suppressor of cytokine signaling 5 0.00746867
NRIP1 nuclear receptor interacting protein 1 0.00744886
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00744036
SYNJ2 synaptojanin 2 0.00742364
OSMR oncostatin M receptor 0.007416
EXPH5 exophilin 5 0.00741169
CHKA choline kinase alpha 0.00741058
PMM2 phosphomannomutase 2 0.00739306
GLS glutaminase 0.00736182
NNT nicotinamide nucleotide transhydrogenase 0.00735475
PSD3 pleckstrin and Sec7 domain containing 3 0.00735186
CPB1 carboxypeptidase B1 (tissue) 0.00734458
ABHD3 abhydrolase domain containing 3 0.00732482
CD164 CD164 molecule, sialomucin 0.00731465
AKR1C2 aldo-keto reductase family 1, member C2 0.00731428
TMEM260 transmembrane protein 260 0.00731355
SLC46A3 solute carrier family 46, member 3 0.00731137
SC5D sterol-C5-desaturase 0.00730055
PNMA2 paraneoplastic Ma antigen 2 0.00728632
UBE3C ubiquitin protein ligase E3C 0.00727279
KCTD9 potassium channel tetramerization domain containing 9 0.00726136
DMD dystrophin 0.00725759
NECTIN3 nectin cell adhesion molecule 3 0.00724756
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00724247
OXTR oxytocin receptor 0.0072414
REV1 REV1, polymerase (DNA directed) 0.00723394
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00723153
DLG1 discs, large homolog 1 (Drosophila) 0.00722635
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00721463
ELP1 elongator acetyltransferase complex subunit 1 0.00719466
ORM1 orosomucoid 1 0.0071756
CHN2 chimerin 2 0.00717028
SGPP1 sphingosine-1-phosphate phosphatase 1 0.0071526
GOLIM4 golgi integral membrane protein 4 0.00714075
CBX5 chromobox homolog 5 0.00713192
SAP30 Sin3A-associated protein, 30kDa 0.00712111
KAT6B K(lysine) acetyltransferase 6B 0.00711021
PEG3 paternally expressed 3 0.00708747
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00708232
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00707867
DYNLL1 dynein, light chain, LC8-type 1 0.00706042
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.00705677
DUT deoxyuridine triphosphatase 0.00702855
COL3A1 collagen, type III, alpha 1 0.00702457
DMXL2 Dmx-like 2 0.00701108
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00700466
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 0.00700161
STARD13 StAR-related lipid transfer (START) domain containing 13 0.00697868
EML4 echinoderm microtubule associated protein like 4 0.00697684
KCTD14 potassium channel tetramerization domain containing 14 0.00697351
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00697207
CCP110 centriolar coiled coil protein 110kDa 0.006963
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.00696237
BTBD3 BTB (POZ) domain containing 3 0.00696059
TM2D3 TM2 domain containing 3 0.00695813
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00695812
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.00694611
CHD7 chromodomain helicase DNA binding protein 7 0.00692208
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.0069133
DPY19L4 dpy-19-like 4 (C. elegans) 0.0069126
YME1L1 YME1-like 1 ATPase 0.00690252
MAGEA12 melanoma antigen family A12 0.00687767
TMEM135 transmembrane protein 135 0.00687263
FDX1 ferredoxin 1 0.00687114
NOTCH2NL notch 2 N-terminal like 0.006866
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.00686379
CNOT7 CCR4-NOT transcription complex, subunit 7 0.00685945
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00684437
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.00684404
IL6ST interleukin 6 signal transducer 0.00684117
EPS8 epidermal growth factor receptor pathway substrate 8 0.00683349
DAPK1 death-associated protein kinase 1 0.00683022
PDPK1 3-phosphoinositide dependent protein kinase 1 0.00681631
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00681212
RNF111 ring finger protein 111 0.0068119
EFHD2 EF-hand domain family, member D2 0.00680324
HNMT histamine N-methyltransferase 0.00678043
TNC tenascin C 0.00676906
NPTN neuroplastin 0.00674559
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00674467
EFR3A EFR3 homolog A (S. cerevisiae) 0.00674451
AHSG alpha-2-HS-glycoprotein 0.00673481
RTN2 reticulon 2 0.00673349
C1QB complement component 1, q subcomponent, B chain 0.00673103
AKR1C3 aldo-keto reductase family 1, member C3 0.00671613
MARCHF6 membrane associated ring-CH-type finger 6 0.00670848
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00670666
FNDC3B fibronectin type III domain containing 3B 0.00669307
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.00668976
H2AX H2A.X variant histone 0.00668141
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.00667682
CEP350 centrosomal protein 350kDa 0.00667442
NES nestin 0.00664167
ASPH aspartate beta-hydroxylase 0.00663297
GPI glucose-6-phosphate isomerase 0.00662954
CPD carboxypeptidase D 0.0066134
TRPS1 trichorhinophalangeal syndrome I 0.00660086
FRY furry homolog (Drosophila) 0.0065878
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.00656367
EFNB2 ephrin-B2 0.00652981
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0065096
MCOLN1 mucolipin 1 0.00650643
ZWILCH zwilch kinetochore protein 0.00650289
SUB1 SUB1 homolog (S. cerevisiae) 0.00649754
CREBZF CREB/ATF bZIP transcription factor 0.00648882
CEP170 centrosomal protein 170kDa 0.00648688
COMT catechol-O-methyltransferase 0.00648601
CLIP3 CAP-GLY domain containing linker protein 3 0.00648258
MANSC1 MANSC domain containing 1 0.00647873
KLHL23 kelch-like family member 23 0.00647545
ELOVL2 ELOVL fatty acid elongase 2 0.00647482
AKR1C1 aldo-keto reductase family 1, member C1 0.00645761
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.00643535
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00643028
MMP2 matrix metallopeptidase 2 0.00641329
RNPS1 RNA binding protein S1, serine-rich domain 0.00641222
FEM1B fem-1 homolog b (C. elegans) 0.00639919
DST dystonin 0.00639884
ZBTB20 zinc finger and BTB domain containing 20 0.00639239
SPEN spen family transcriptional repressor 0.00638161
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.00638031
EXOC5 exocyst complex component 5 0.00636991
MPZL2 myelin protein zero-like 2 0.00634006
IGSF1 immunoglobulin superfamily, member 1 0.00633689
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00633568
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 0.00632896
YAP1 Yes-associated protein 1 0.00632533
ZWINT ZW10 interacting kinetochore protein 0.00632116
SCAMP1 secretory carrier membrane protein 1 0.00631894
ACVR1 activin A receptor, type I 0.00631313
PHYH phytanoyl-CoA 2-hydroxylase 0.00630199
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00628296
RAPSN receptor-associated protein of the synapse 0.00627734
ZNF91 zinc finger protein 91 0.00627133
TMED5 transmembrane emp24 protein transport domain containing 5 0.00626816
SOS2 son of sevenless homolog 2 (Drosophila) 0.00625187
MERTK MER proto-oncogene, tyrosine kinase 0.00623542
SHTN1 shootin 1 0.00623349
VSIG4 V-set and immunoglobulin domain containing 4 0.00623245
C4BPA complement component 4 binding protein, alpha 0.00622828
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00622143

decreased expression

Symbol Name Standardized Value
IFITM1 interferon induced transmembrane protein 1 -0.0149706
MAL mal, T-cell differentiation protein -0.0147623
GJA1 gap junction protein, alpha 1, 43kDa -0.0139091
COG7 component of oligomeric golgi complex 7 -0.0135223
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0133247
TUBB2A tubulin, beta 2A class IIa -0.0129574
GRB7 growth factor receptor-bound protein 7 -0.0128688
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.0126478
ADIRF adipogenesis regulatory factor -0.0124448
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.0119761
CSTA cystatin A (stefin A) -0.0119536
BAMBI BMP and activin membrane-bound inhibitor -0.0115071
ITM2C integral membrane protein 2C -0.0114416
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.0111867
ISG20 interferon stimulated exonuclease gene 20kDa -0.0109564
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.0109141
ECM1 extracellular matrix protein 1 -0.0108476
GYPC glycophorin C (Gerbich blood group) -0.0105826
STK10 serine/threonine kinase 10 -0.0104768
SPON1 spondin 1, extracellular matrix protein -0.0103461
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.0102933
BAG3 BCL2-associated athanogene 3 -0.0102178
AQP3 aquaporin 3 (Gill blood group) -0.0101878
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0100715
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00986621
FABP4 fatty acid binding protein 4, adipocyte -0.00984354
IFI27 interferon, alpha-inducible protein 27 -0.00983656
GSTP1 glutathione S-transferase pi 1 -0.0098294
ASS1 argininosuccinate synthase 1 -0.0098052
MMP10 matrix metallopeptidase 10 -0.00980136
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00979037
AQP1 aquaporin 1 (Colton blood group) -0.00976363
AEBP1 AE binding protein 1 -0.00973095
NVL nuclear VCP-like -0.00970207
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00968397
LMCD1 LIM and cysteine-rich domains 1 -0.00967805
WARS1 tryptophanyl-tRNA synthetase 1 -0.00954584
ATF3 activating transcription factor 3 -0.00951648
MSMB microseminoprotein, beta- -0.00949652
IRF7 interferon regulatory factor 7 -0.00949335
TKTL1 transketolase-like 1 -0.00940615
DIPK1A divergent protein kinase domain 1A -0.00937758
KRT13 keratin 13, type I -0.00937384
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00936044
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00934774
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0093028
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00917783
EIF5A eukaryotic translation initiation factor 5A -0.00906769
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00904225
PYCARD PYD and CARD domain containing -0.00902888
CCL5 chemokine (C-C motif) ligand 5 -0.00892837
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -0.0089098
C6ORF48 chromosome 6 open reading frame 48 -0.00884131
CALB1 calbindin 1, 28kDa -0.00878555
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00877997
ATF4 activating transcription factor 4 -0.00876884
TRIB2 tribbles pseudokinase 2 -0.00874154
KLK11 kallikrein-related peptidase 11 -0.00873176
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.00861994
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00859009
CTBP2 C-terminal binding protein 2 -0.00857919
TUFT1 tuftelin 1 -0.00856832
SLC44A4 solute carrier family 44, member 4 -0.00852205
KRT5 keratin 5, type II -0.00849592
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.00848359
RGCC regulator of cell cycle -0.008471
ACP3 acid phosphatase 3 -0.00844928
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00840502
NARF nuclear prelamin A recognition factor -0.00836632
BIRC3 baculoviral IAP repeat containing 3 -0.00835145
EZR ezrin -0.00835105
RGS10 regulator of G-protein signaling 10 -0.00831827
PLAU plasminogen activator, urokinase -0.00827118
PSAP prosaposin -0.00823042
AHNAK2 AHNAK nucleoprotein 2 -0.00819894
NXN nucleoredoxin -0.00814315
CLDN7 claudin 7 -0.00810551
THY1 Thy-1 cell surface antigen -0.00809653
GZMK granzyme K (granzyme 3; tryptase II) -0.0080652
GMPR guanosine monophosphate reductase -0.008049
RRAD Ras-related associated with diabetes -0.00799614
BCHE butyrylcholinesterase -0.00798581
NDRG1 N-myc downstream regulated 1 -0.00793554
CHKB choline kinase beta -0.00793149
THBS2 thrombospondin 2 -0.00792983
HLA-B major histocompatibility complex, class I, B -0.0079206
RPA2 replication protein A2, 32kDa -0.00789579
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00787759
PWP1 PWP1 homolog (S. cerevisiae) -0.00784416
CSRP2 cysteine and glycine-rich protein 2 -0.00783203
KRT6A keratin 6A, type II -0.00781436
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00780649
SST somatostatin -0.0078047
SINHCAF SIN3-HDAC complex associated factor -0.00776046
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00770808
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00769908
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0076884
HSPB1 heat shock 27kDa protein 1 -0.00765122
MX1 MX dynamin-like GTPase 1 -0.00763898
MX2 MX dynamin-like GTPase 2 -0.0076287
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00760821
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.00757735
GAL galanin/GMAP prepropeptide -0.00756398
TFF1 trefoil factor 1 -0.00751628
CD8A CD8a molecule -0.00748873
GSTZ1 glutathione S-transferase zeta 1 -0.00748552
OCRL oculocerebrorenal syndrome of Lowe -0.00747975
IER2 immediate early response 2 -0.00747673
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00746821
MMP12 matrix metallopeptidase 12 -0.00746154
CRCT1 cysteine-rich C-terminal 1 -0.00744037
EHD3 EH-domain containing 3 -0.0074187
IRF8 interferon regulatory factor 8 -0.00735731
INHBA inhibin, beta A -0.00731595
PFKM phosphofructokinase, muscle -0.00729695
CCK cholecystokinin -0.00728833
FXYD2 FXYD domain containing ion transport regulator 2 -0.00727393
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00726658
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00726296
VCAM1 vascular cell adhesion molecule 1 -0.00725113
FKBP9 FK506 binding protein 9, 63 kDa -0.00724591
QPCT glutaminyl-peptide cyclotransferase -0.00721535
HSPA2 heat shock 70kDa protein 2 -0.00719072
BPGM 2,3-bisphosphoglycerate mutase -0.00718135
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00717013
HAL histidine ammonia-lyase -0.00713319
RHCG Rh family, C glycoprotein -0.00713014
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00712321
TAPBP TAP binding protein (tapasin) -0.00710992
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00709673
SLC25A46 solute carrier family 25, member 46 -0.00709646
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00709526
EAF2 ELL associated factor 2 -0.00707944
VAMP8 vesicle-associated membrane protein 8 -0.00704919
ZFP36L2 ZFP36 ring finger protein-like 2 -0.0070125
H1-10 H1.10 linker histone -0.00701192
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00701066
ZNF451 zinc finger protein 451 -0.00700268
XPO7 exportin 7 -0.00698798
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -0.00698242
C10ORF10 chromosome 10 open reading frame 10 -0.00698166
NKG7 natural killer cell granule protein 7 -0.00697163
SP110 SP110 nuclear body protein -0.00695503
TSPAN13 tetraspanin 13 -0.00695426
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00692711
CHRDL1 chordin-like 1 -0.00692483
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00691371
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.0069113
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00690609
SET SET nuclear proto-oncogene -0.00689916
CRELD2 cysteine-rich with EGF-like domains 2 -0.00688618
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.00687768
MME membrane metallo-endopeptidase -0.0068773
SARS1 seryl-tRNA synthetase 1 -0.00685834
PRUNE2 prune homolog 2 (Drosophila) -0.00685745
CST7 cystatin F (leukocystatin) -0.00685167
CDC42 cell division cycle 42 -0.00683968
MLPH melanophilin -0.00683156
FECH ferrochelatase -0.00682451
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.006816
FHOD3 formin homology 2 domain containing 3 -0.00681406
RPS5 ribosomal protein S5 -0.00678799
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00677602
PTGES prostaglandin E synthase -0.00672448
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00669639
MMP11 matrix metallopeptidase 11 -0.00668684
ERP29 endoplasmic reticulum protein 29 -0.00667414
CD248 CD248 molecule, endosialin -0.00664869
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00663252
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00661394
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -0.00660491
COPS7A COP9 signalosome subunit 7A -0.00659744
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00657827
IRF1 interferon regulatory factor 1 -0.00656964
PLLP plasmolipin -0.00656593
HMGA1 high mobility group AT-hook 1 -0.00656439
MRPS7 mitochondrial ribosomal protein S7 -0.0065563
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00655121
BACE2 beta-site APP-cleaving enzyme 2 -0.0065479
RPL14 ribosomal protein L14 -0.00654208
VTI1B vesicle transport through interaction with t-SNAREs 1B -0.00651177
PRR13 proline rich 13 -0.00650719
ATOX1 antioxidant 1 copper chaperone -0.00649041
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00648845
OSR2 odd-skipped related transciption factor 2 -0.00648635
AHCY adenosylhomocysteinase -0.00647621
PRR5 proline rich 5 (renal) -0.00647568
TXNIP thioredoxin interacting protein -0.00646781
CCN2 cellular communication network factor 2 -0.00646129
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.00646074
ZNF185 zinc finger protein 185 (LIM domain) -0.00645033
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00644299
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -0.00643106
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00642064
MYRF myelin regulatory factor -0.00640599
USP18 ubiquitin specific peptidase 18 -0.00640412
YPEL5 yippee-like 5 (Drosophila) -0.00639421
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00639238
MDK midkine (neurite growth-promoting factor 2) -0.00639065
POU4F1 POU class 4 homeobox 1 -0.00638822
MXI1 MAX interactor 1, dimerization protein -0.0063738
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00636877
AMZ2 archaelysin family metallopeptidase 2 -0.0063586
SAP18 Sin3A-associated protein, 18kDa -0.00634996
NDN necdin, melanoma antigen (MAGE) family member -0.00634545
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00632569
CRYBG1 crystallin beta-gamma domain containing 1 -0.00632471
MFAP2 microfibrillar-associated protein 2 -0.00631944
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00631401
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00629642
SUGCT succinyl-CoA:glutarate-CoA transferase -0.00629468
GNLY granulysin -0.00628544
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.00626336
SMYD3 SET and MYND domain containing 3 -0.0062453
CCR7 chemokine (C-C motif) receptor 7 -0.00624302
GREM1 gremlin 1, DAN family BMP antagonist -0.00624256
IFITM3 interferon induced transmembrane protein 3 -0.00624102
CST1 cystatin SN -0.00623065
CDH16 cadherin 16, KSP-cadherin -0.00622591
CYB5A cytochrome b5 type A (microsomal) -0.0062131
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -0.00620184
TOR3A torsin family 3, member A -0.00619914
LAMP3 lysosomal-associated membrane protein 3 -0.00619832
C21ORF33 chromosome 21 open reading frame 33 -0.00619564
EPHA1 EPH receptor A1 -0.00619361
CD36 CD36 molecule (thrombospondin receptor) -0.00618542
BLMH bleomycin hydrolase -0.00616039
ASRGL1 asparaginase like 1 -0.00615931
FMO1 flavin containing monooxygenase 1 -0.00615858
BTN3A1 butyrophilin, subfamily 3, member A1 -0.00614801
GIMAP4 GTPase, IMAP family member 4 -0.0061455
LXN latexin -0.00614107
RNH1 ribonuclease/angiogenin inhibitor 1 -0.0061212
ACP5 acid phosphatase 5, tartrate resistant -0.00611849
IFI16 interferon, gamma-inducible protein 16 -0.00609733
AHSP alpha hemoglobin stabilizing protein -0.00608848
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00608188
SELENBP1 selenium binding protein 1 -0.00608049
JPT1 Jupiter microtubule associated homolog 1 -0.00606789
OAT ornithine aminotransferase -0.00606764
SLC38A2 solute carrier family 38, member 2 -0.00605791
TPM2 tropomyosin 2 (beta) -0.00605777
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00605329
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00605164
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene -0.00604538
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00603215
PARL presenilin associated, rhomboid-like -0.00602138
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.00601581
DDIT3 DNA-damage-inducible transcript 3 -0.00598528
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00598125