PRPF4B Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description pre-mRNA processing factor 4B|Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8899)
External Link https://ncbi.nlm.nih.gov/gene/8899
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Genes

500 genes differentially expressed following the PRPF4B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LTF lactotransferrin 0.0126325
KRT13 keratin 13, type I 0.0117018
CA12 carbonic anhydrase XII 0.0107182
ZDHHC6 zinc finger, DHHC-type containing 6 0.0101754
SPRR3 small proline-rich protein 3 0.00980461
CHGB chromogranin B 0.00952157
RGCC regulator of cell cycle 0.00940997
MME membrane metallo-endopeptidase 0.00926255
EGR1 early growth response 1 0.00896649
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00873013
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00864191
KLF6 Kruppel-like factor 6 0.00857731
VWA8 von Willebrand factor A domain containing 8 0.00853027
CRYAB crystallin, alpha B 0.00832384
TFRC transferrin receptor 0.00818771
ZMYM2 zinc finger, MYM-type 2 0.00812572
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00798884
KRT14 keratin 14, type I 0.00795746
GSTP1 glutathione S-transferase pi 1 0.00791962
LCN2 lipocalin 2 0.00780278
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00753103
CD81 CD81 molecule 0.00752594
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00751488
RBM47 RNA binding motif protein 47 0.00750892
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00744423
RHCG Rh family, C glycoprotein 0.00742969
COG7 component of oligomeric golgi complex 7 0.00742569
KRT19 keratin 19, type I 0.00739214
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00735681
PDE4DIP phosphodiesterase 4D interacting protein 0.00732726
HEATR1 HEAT repeat containing 1 0.00725447
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00720594
PCDH9 protocadherin 9 0.00716833
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00714924
QPRT quinolinate phosphoribosyltransferase 0.00714055
HSPB8 heat shock 22kDa protein 8 0.00712996
CRABP2 cellular retinoic acid binding protein 2 0.00711927
MRPS31 mitochondrial ribosomal protein S31 0.0070638
SAP18 Sin3A-associated protein, 18kDa 0.0070337
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00703368
HSPH1 heat shock 105kDa/110kDa protein 1 0.00698251
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00696763
ATF3 activating transcription factor 3 0.0069645
MVP major vault protein 0.00695618
MAB21L1 mab-21-like 1 (C. elegans) 0.00694739
MEIS2 Meis homeobox 2 0.00688393
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00684662
MPHOSPH8 M-phase phosphoprotein 8 0.00680269
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0067525
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00675163
MET MET proto-oncogene, receptor tyrosine kinase 0.00673004
KRT81 keratin 81, type II 0.00672355
ATF4 activating transcription factor 4 0.0067197
SRPX sushi-repeat containing protein, X-linked 0.00670252
PHF11 PHD finger protein 11 0.00669068
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.0066499
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00661117
HBD hemoglobin, delta 0.00657992
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.00656825
S100A10 S100 calcium binding protein A10 0.00656069
KRT5 keratin 5, type II 0.00646479
PARP4 poly (ADP-ribose) polymerase family, member 4 0.00644381
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00642645
KDM3A lysine (K)-specific demethylase 3A 0.00642337
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00640477
TMEM255A transmembrane protein 255A 0.00638129
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00636667
ECM1 extracellular matrix protein 1 0.00635909
SFRP1 secreted frizzled-related protein 1 0.00634085
PUF60 poly-U binding splicing factor 60KDa 0.00632961
GPI glucose-6-phosphate isomerase 0.00632735
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00631375
NES nestin 0.00624606
DNTT DNA nucleotidylexotransferase 0.00622573
FGB fibrinogen beta chain 0.00622357
PXDN peroxidasin 0.00622035
AKAP8 A kinase (PRKA) anchor protein 8 0.0062192
PFKM phosphofructokinase, muscle 0.00621696
ZC3H13 zinc finger CCCH-type containing 13 0.00620471
S100A12 S100 calcium binding protein A12 0.00620369
YBX3 Y box binding protein 3 0.00619714
PLIN3 perilipin 3 0.00617965
RBM8A RNA binding motif protein 8A 0.00614944
S100A11 S100 calcium binding protein A11 0.00614918
EFCAB14 EF-hand calcium binding domain 14 0.00614253
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00613178
MXI1 MAX interactor 1, dimerization protein 0.00612062
ADD3 adducin 3 (gamma) 0.00611694
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00611171
GPNMB glycoprotein (transmembrane) nmb 0.00607654
ESD esterase D 0.00606547
TMPRSS11E transmembrane protease, serine 11E 0.00603535
ZMYND8 zinc finger, MYND-type containing 8 0.00600279
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00596053
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.0059337
TRAF5 TNF receptor-associated factor 5 0.00592542
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00586404
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00585761
IRS2 insulin receptor substrate 2 0.00583721
RRAGD Ras-related GTP binding D 0.00583593
VTN vitronectin 0.00582401
CSRP2 cysteine and glycine-rich protein 2 0.00580355
PTN pleiotrophin 0.00577249
CORO2B coronin, actin binding protein, 2B 0.00577101
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00576775
ADAM10 ADAM metallopeptidase domain 10 0.00575266
HSPB1 heat shock 27kDa protein 1 0.00572981
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00571151
LAMB1 laminin, beta 1 0.00569143
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00568735
TUBB6 tubulin, beta 6 class V 0.00567769
FGA fibrinogen alpha chain 0.00565305
FXR1 fragile X mental retardation, autosomal homolog 1 0.00565068
ADM adrenomedullin 0.00563748
PSCA prostate stem cell antigen 0.00560821
PHB prohibitin 0.00559318
IVNS1ABP influenza virus NS1A binding protein 0.00555527
GYPC glycophorin C (Gerbich blood group) 0.00550976
AGTR1 angiotensin II receptor, type 1 0.00550091
GSDME gasdermin E 0.00549312
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00549013
HMGA2 high mobility group AT-hook 2 0.00544411
LY6D lymphocyte antigen 6 complex, locus D 0.00543561
LXN latexin 0.00543301
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00542774
MELK maternal embryonic leucine zipper kinase 0.00541842
YME1L1 YME1-like 1 ATPase 0.00541415
PGBD5 piggyBac transposable element derived 5 0.00541392
XIC X chromosome inactivation center 0.00537559
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.005375
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.00535786
RPIA ribose 5-phosphate isomerase A 0.00534547
CAPG capping protein (actin filament), gelsolin-like 0.00532414
FGG fibrinogen gamma chain 0.00529935
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00528896
SRSF5 serine/arginine-rich splicing factor 5 0.00527144
MDH1 malate dehydrogenase 1, NAD (soluble) 0.00525624
CNR1 cannabinoid receptor 1 (brain) 0.00525164
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00523848
RSRC2 arginine/serine-rich coiled-coil 2 0.00523656
C1S complement component 1, s subcomponent 0.00523137
GSTK1 glutathione S-transferase kappa 1 0.00520034
RNF6 ring finger protein (C3H2C3 type) 6 0.00519071
ENAH enabled homolog (Drosophila) 0.00517665
TTR transthyretin 0.00516798
ZNF394 zinc finger protein 394 0.00516656
CXCL5 chemokine (C-X-C motif) ligand 5 0.0051502
IL1RN interleukin 1 receptor antagonist 0.00514742
ADA adenosine deaminase 0.00514181
ACTB actin, beta 0.0051375
KLK10 kallikrein-related peptidase 10 0.00513211
EIF6 eukaryotic translation initiation factor 6 0.0051301
MXRA5 matrix-remodelling associated 5 0.00512597
SH3YL1 SH3 and SYLF domain containing 1 0.00512288
TLK2 tousled-like kinase 2 0.00511638
RSL1D1 ribosomal L1 domain containing 1 0.00511134
HSPA1A heat shock 70kDa protein 1A 0.00510936
TRAF3IP2 TRAF3 interacting protein 2 0.0051063
TP53 tumor protein p53 0.00508461
COG2 component of oligomeric golgi complex 2 0.00506117
STC1 stanniocalcin 1 0.00505874
PADI3 peptidyl arginine deiminase, type III 0.0050553
PALLD palladin, cytoskeletal associated protein 0.00504862
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.00504432
FOLR1 folate receptor 1 (adult) 0.0050439
MFAP5 microfibrillar associated protein 5 0.00504132
SPTBN1 spectrin, beta, non-erythrocytic 1 0.00502241
PRDX2 peroxiredoxin 2 0.00501575
CXCL8 chemokine (C-X-C motif) ligand 8 0.00500388
USPL1 ubiquitin specific peptidase like 1 0.00500255
IL1A interleukin 1, alpha 0.00497099
BAG3 BCL2-associated athanogene 3 0.00496858
BIN1 bridging integrator 1 0.00496772
GLUL glutamate-ammonia ligase 0.00496617
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00496194
GABPB1 GA binding protein transcription factor, beta subunit 1 0.00494544
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00494455
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00493937
ELP1 elongator acetyltransferase complex subunit 1 0.004937
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0049085
GTPBP4 GTP binding protein 4 0.0049048
CALB1 calbindin 1, 28kDa 0.00489531
MMP9 matrix metallopeptidase 9 0.00488768
SEPTIN9 septin 9 0.00488733
IL32 interleukin 32 0.00486745
CFB complement factor B 0.00486546
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00485593
LDB3 LIM domain binding 3 0.00484858
SNX1 sorting nexin 1 0.00484619
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.0048014
MPO myeloperoxidase 0.00479305
HMGB1 high mobility group box 1 0.00478928
UFM1 ubiquitin-fold modifier 1 0.00478495
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.00477915
TNIP1 TNFAIP3 interacting protein 1 0.00477405
PELI1 pellino E3 ubiquitin protein ligase 1 0.00476964
EIF3D eukaryotic translation initiation factor 3, subunit D 0.00476924
H1-0 H1.0 linker histone 0.0047643
FGF9 fibroblast growth factor 9 0.0047633
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00475676
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.00475384
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00473371
MICU2 mitochondrial calcium uptake 2 0.0047182
BIK BCL2-interacting killer (apoptosis-inducing) 0.00471461
PRDX1 peroxiredoxin 1 0.00470495
PRPF18 pre-mRNA processing factor 18 0.0047049
RADX RPA1 related single stranded DNA binding protein, X-linked 0.00470167
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00469556
MZB1 marginal zone B and B1 cell-specific protein 0.0046855
NTS neurotensin 0.00467158
EIF4B eukaryotic translation initiation factor 4B 0.00466969
RBM39 RNA binding motif protein 39 0.0046684
WNK1 WNK lysine deficient protein kinase 1 0.00465384
TPM4 tropomyosin 4 0.00465316
POU2AF1 POU class 2 associating factor 1 0.00465196
MID1 midline 1 0.00464575
ZBED2 zinc finger, BED-type containing 2 0.00464244
MSRB2 methionine sulfoxide reductase B2 0.00464185
PARD3 par-3 family cell polarity regulator 0.00463401
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00462984
IFI16 interferon, gamma-inducible protein 16 0.0046296
GPX3 glutathione peroxidase 3 0.00462089
USP9X ubiquitin specific peptidase 9, X-linked 0.00460549
RALGDS ral guanine nucleotide dissociation stimulator 0.00460262
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0045941
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00457841
TCL1A T-cell leukemia/lymphoma 1A 0.00457579
ZFP36L2 ZFP36 ring finger protein-like 2 0.0045664
MAL mal, T-cell differentiation protein 0.00455626
MAP1A microtubule-associated protein 1A 0.00455233
CTSH cathepsin H 0.00454724
ZNF395 zinc finger protein 395 0.00454672
SOD2 superoxide dismutase 2, mitochondrial 0.00454074
TTN titin 0.00451844
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00451733
LRRC59 leucine rich repeat containing 59 0.00451528
CTSB cathepsin B 0.00451342
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.00450653
SLC35G2 solute carrier family 35, member G2 0.00450449
RHOH ras homolog family member H 0.00449223
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00448834
RBM26 RNA binding motif protein 26 0.00447706
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.00446607
EIF4A1 eukaryotic translation initiation factor 4A1 0.00446541
SPRY2 sprouty homolog 2 (Drosophila) 0.00446224
TBC1D4 TBC1 domain family, member 4 0.00446151
EPS8L2 EPS8-like 2 0.0044611
ZNF91 zinc finger protein 91 0.00445937
NOP53 NOP53 ribosome biogenesis factor 0.00445328
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.00444555

decreased expression

Symbol Name Standardized Value
THBS1 thrombospondin 1 -0.0134799
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0124371
TXNDC9 thioredoxin domain containing 9 -0.0124297
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0110988
SRGN serglycin -0.01066
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0106199
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0105128
TMSB15A thymosin beta 15a -0.0102811
TMEM45A transmembrane protein 45A -0.00986026
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -0.00960822
MGP matrix Gla protein -0.0093415
TYROBP TYRO protein tyrosine kinase binding protein -0.00930899
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0092513
GLIPR1 GLI pathogenesis-related 1 -0.00906636
TSPAN8 tetraspanin 8 -0.00889672
HOXC6 homeobox C6 -0.00889533
HOPX HOP homeobox -0.00870455
DUSP22 dual specificity phosphatase 22 -0.00865213
KIF20A kinesin family member 20A -0.00844029
CLEC2B C-type lectin domain family 2, member B -0.00840225
AXL AXL receptor tyrosine kinase -0.00834867
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00827509
ALCAM activated leukocyte cell adhesion molecule -0.00822003
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00819981
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -0.00815404
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00811133
LYZ lysozyme -0.00806446
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.0080584
ARHGAP29 Rho GTPase activating protein 29 -0.00794975
ISG15 ISG15 ubiquitin-like modifier -0.0078524
HOXC10 homeobox C10 -0.00774349
GSTM3 glutathione S-transferase mu 3 (brain) -0.00773855
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00771814
CD93 CD93 molecule -0.00766877
PDGFC platelet derived growth factor C -0.00755991
CLGN calmegin -0.00754732
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -0.00752278
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00750279
LRRC17 leucine rich repeat containing 17 -0.00749718
CLCA1 chloride channel accessory 1 -0.00748221
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00734538
RPA3 replication protein A3, 14kDa -0.00733428
IGFBP5 insulin-like growth factor binding protein 5 -0.00726406
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00717417
PEG3 paternally expressed 3 -0.00713063
PRAME preferentially expressed antigen in melanoma -0.00707634
MANSC1 MANSC domain containing 1 -0.00705509
MDK midkine (neurite growth-promoting factor 2) -0.00701077
NPY1R neuropeptide Y receptor Y1 -0.00695896
OLFM1 olfactomedin 1 -0.00692797
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0067913
TSPAN13 tetraspanin 13 -0.00678921
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.0067853
FGFR3 fibroblast growth factor receptor 3 -0.00678119
SIDT2 SID1 transmembrane family, member 2 -0.0067386
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00672865
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00671254
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00671055
EVI2A ecotropic viral integration site 2A -0.00669345
ZSCAN31 zinc finger and SCAN domain containing 31 -0.00667043
AGR2 anterior gradient 2 -0.00666428
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00665296
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -0.00662618
CRIP2 cysteine-rich protein 2 -0.00662047
SELENOW selenoprotein W -0.0065762
METTL7A methyltransferase like 7A -0.0065648
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.00656471
CYBRD1 cytochrome b reductase 1 -0.00656374
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00645025
FRZB frizzled-related protein -0.00643177
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00643037
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00635889
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00634883
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00631793
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00629907
QKI QKI, KH domain containing, RNA binding -0.00627279
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00622893
ZW10 zw10 kinetochore protein -0.00622498
DACH1 dachshund family transcription factor 1 -0.00622087
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.00614993
CADPS2 Ca++-dependent secretion activator 2 -0.00612962
MPZL2 myelin protein zero-like 2 -0.00609788
COMP cartilage oligomeric matrix protein -0.00609021
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00608181
DLK1 delta-like 1 homolog (Drosophila) -0.00606296
MAPK9 mitogen-activated protein kinase 9 -0.00605974
AHR aryl hydrocarbon receptor -0.00599656
ADGRF5 adhesion G protein-coupled receptor F5 -0.00589004
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00588657
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00582615
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00581935
DOCK4 dedicator of cytokinesis 4 -0.00579965
NEFH neurofilament, heavy polypeptide -0.00579726
KCTD12 potassium channel tetramerization domain containing 12 -0.00577608
ETNK1 ethanolamine kinase 1 -0.00576532
LY86 lymphocyte antigen 86 -0.00576352
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.00575484
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.0057484
TOR1A torsin family 1, member A (torsin A) -0.00572284
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00572224
RHOB ras homolog family member B -0.00571588
ASF1A anti-silencing function 1A histone chaperone -0.00570547
TSPAN7 tetraspanin 7 -0.00568922
LOR loricrin -0.00567464
KRT10 keratin 10, type I -0.00566985
RGS10 regulator of G-protein signaling 10 -0.00565225
CDC42 cell division cycle 42 -0.00565138
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00564489
ARG2 arginase 2 -0.0056267
HYOU1 hypoxia up-regulated 1 -0.00562184
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00560764
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00557819
PLN phospholamban -0.00555277
PEX10 peroxisomal biogenesis factor 10 -0.00554974
TMEM50B transmembrane protein 50B -0.00554834
NRGN neurogranin (protein kinase C substrate, RC3) -0.00553907
KLHL21 kelch-like family member 21 -0.00553379
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00552525
GSTA4 glutathione S-transferase alpha 4 -0.00551685
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -0.00548767
NR3C2 nuclear receptor subfamily 3, group C, member 2 -0.00548604
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00546958
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00545843
COL9A3 collagen, type IX, alpha 3 -0.00545052
MAOA monoamine oxidase A -0.00544607
PLA2G12A phospholipase A2, group XIIA -0.0054363
FABP1 fatty acid binding protein 1, liver -0.00540551
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00539893
KIF1A kinesin family member 1A -0.00537836
MPC1 mitochondrial pyruvate carrier 1 -0.00536388
PRSS8 protease, serine, 8 -0.00536269
CDKN3 cyclin-dependent kinase inhibitor 3 -0.0053509
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00534094
BARD1 BRCA1 associated RING domain 1 -0.00533053
CD1D CD1d molecule -0.00533004
NVL nuclear VCP-like -0.00528871
ADRA2A adrenoceptor alpha 2A -0.00527968
NMU neuromedin U -0.00526427
IFI44 interferon-induced protein 44 -0.00525245
NADK NAD kinase -0.00524523
IL10RA interleukin 10 receptor, alpha -0.00523281
PTS 6-pyruvoyltetrahydropterin synthase -0.00521504
DMAC2L distal membrane arm assembly component 2 like -0.00521477
LIMCH1 LIM and calponin homology domains 1 -0.00520746
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00520475
CALML5 calmodulin-like 5 -0.00517807
LIPT1 lipoyltransferase 1 -0.00513604
PDCD2 programmed cell death 2 -0.00513097
NANS N-acetylneuraminic acid synthase -0.0051246
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00511575
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0051139
DMBT1 deleted in malignant brain tumors 1 -0.00511085
AGA aspartylglucosaminidase -0.00509538
ANOS1 anosmin 1 -0.00509217
TKTL1 transketolase-like 1 -0.00508936
BIRC2 baculoviral IAP repeat containing 2 -0.0050843
REPS2 RALBP1 associated Eps domain containing 2 -0.0050523
BMP6 bone morphogenetic protein 6 -0.00504743
CCN2 cellular communication network factor 2 -0.00504401
RTN1 reticulon 1 -0.0050434
NCF2 neutrophil cytosolic factor 2 -0.00503358
GPA33 glycoprotein A33 (transmembrane) -0.00503319
TM7SF2 transmembrane 7 superfamily member 2 -0.00503157
REG1A regenerating islet-derived 1 alpha -0.00502664
KLHL23 kelch-like family member 23 -0.00501719
APMAP adipocyte plasma membrane associated protein -0.00499995
FAT4 FAT atypical cadherin 4 -0.00499149
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00499015
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00498852
ACAT2 acetyl-CoA acetyltransferase 2 -0.00494643
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00494589
CRLF1 cytokine receptor-like factor 1 -0.00494542
C11ORF71 chromosome 11 open reading frame 71 -0.00494096
PTCH1 patched 1 -0.00493672
TSPAN12 tetraspanin 12 -0.00491854
CCL5 chemokine (C-C motif) ligand 5 -0.00491777
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -0.00488847
ZNF226 zinc finger protein 226 -0.00488336
CDCA4 cell division cycle associated 4 -0.00487911
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00487343
KYNU kynureninase -0.00486026
CD86 CD86 molecule -0.00485696
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.0048552
MEX3D mex-3 RNA binding family member D -0.00484974
TGFBI transforming growth factor, beta-induced, 68kDa -0.00484694
FBXO3 F-box protein 3 -0.00484463
TYRP1 tyrosinase-related protein 1 -0.00483466
TRIM36 tripartite motif containing 36 -0.00482776
LYPD1 LY6/PLAUR domain containing 1 -0.00482617
KLHDC2 kelch domain containing 2 -0.00481878
ACYP2 acylphosphatase 2, muscle type -0.00481661
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00480847
C2CD5 C2 calcium-dependent domain containing 5 -0.00479789
HLA-DMB major histocompatibility complex, class II, DM beta -0.00479681
TSPYL5 TSPY-like 5 -0.0047849
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00478466
THBD thrombomodulin -0.00478236
HMG20B high mobility group 20B -0.00477966
CREBL2 cAMP responsive element binding protein-like 2 -0.00476129
HMGN3 high mobility group nucleosomal binding domain 3 -0.00475254
SLC44A4 solute carrier family 44, member 4 -0.00475239
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00475105
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00473779
SOCS5 suppressor of cytokine signaling 5 -0.0047331
SCRG1 stimulator of chondrogenesis 1 -0.00471587
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00471501
FAM13B family with sequence similarity 13, member B -0.00471338
ZNF587 zinc finger protein 587 -0.00470851
PRKCZ protein kinase C, zeta -0.00470655
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00469927
PNKP polynucleotide kinase 3'-phosphatase -0.0046896
CLEC7A C-type lectin domain family 7, member A -0.00467957
C5ORF30 chromosome 5 open reading frame 30 -0.00467467
EVI5 ecotropic viral integration site 5 -0.00466892
CNN3 calponin 3, acidic -0.00466841
ICAM2 intercellular adhesion molecule 2 -0.00466782
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.00466099
KRT17 keratin 17, type I -0.00466077
ABHD6 abhydrolase domain containing 6 -0.00465418
SLC2A4RG SLC2A4 regulator -0.0046511
MYH11 myosin, heavy chain 11, smooth muscle -0.0046503
PER3 period circadian clock 3 -0.004649
OIP5 Opa interacting protein 5 -0.00464536
FASN fatty acid synthase -0.00463057
MINDY1 MINDY lysine 48 deubiquitinase 1 -0.00462292
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00460352
KRT20 keratin 20, type I -0.00459676
WNT5A wingless-type MMTV integration site family, member 5A -0.00459413
GLMN glomulin, FKBP associated protein -0.00459013
SAR1B secretion associated, Ras related GTPase 1B -0.00457599
FGL2 fibrinogen-like 2 -0.00457459
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00457044
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) -0.00456976
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -0.00455889
KIAA0513 KIAA0513 -0.00455577
GIMAP6 GTPase, IMAP family member 6 -0.00454964
TOGARAM1 TOG array regulator of axonemal microtubules 1 -0.00454903
NOTCH2NL notch 2 N-terminal like -0.00454878
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.00454355
THAP1 THAP domain containing, apoptosis associated protein 1 -0.00454209
BGN biglycan -0.00452711
MFAP2 microfibrillar-associated protein 2 -0.00452704
CC2D2B coiled-coil and C2 domain containing 2B -0.00452473
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00450176
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.00450013
HLA-DOB major histocompatibility complex, class II, DO beta -0.00450005
HDAC4 histone deacetylase 4 -0.00449236
DCXR dicarbonyl/L-xylulose reductase -0.00449012
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00448904
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00448617