PSAT1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description phosphoserine aminotransferase 1|This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 29968)
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Genes

320 genes differentially expressed following the PSAT1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PTPRC protein tyrosine phosphatase, receptor type, C 2.25865
RXFP2 relaxin/insulin-like family peptide receptor 2 2.25865
NPPB natriuretic peptide B 2.25865
SPINK6 serine peptidase inhibitor, Kazal type 6 2.25865
HCRTR1 hypocretin (orexin) receptor 1 2.25865
AKR1C4 aldo-keto reductase family 1, member C4 2.25865
MUC6 mucin 6, oligomeric mucus/gel-forming 2.25865
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.25865
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.25865
LBP lipopolysaccharide binding protein 2.25865
SWI5 SWI5 recombination repair homolog (yeast) 2.25865
CARD18 caspase recruitment domain family, member 18 2.25865
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.25865
LRRD1 leucine-rich repeats and death domain containing 1 2.25865
FOXD1 forkhead box D1 2.25865
RLBP1 retinaldehyde binding protein 1 2.25865
TBX20 T-box 20 2.25865
SYCP2 synaptonemal complex protein 2 2.25865
SEC61G Sec61 gamma subunit 2.25865
GPR4 G protein-coupled receptor 4 2.25865
HLF hepatic leukemia factor 2.25865
CD5 CD5 molecule 2.25865
INHBA inhibin, beta A 2.25865
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.25865
MYOM3 myomesin 3 2.25865
SLC9C2 solute carrier family 9, member C2 (putative) 2.25865
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.25865
TRUB1 TruB pseudouridine (psi) synthase family member 1 2.25865
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.25865
IL2RA interleukin 2 receptor, alpha 2.25865
TAS2R13 taste receptor, type 2, member 13 2.25865
TSHZ1 teashirt zinc finger homeobox 1 2.25865
CPLX4 complexin 4 2.25865
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.25865
ACY3 aminoacylase 3 2.25865
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.25865
S100A1 S100 calcium binding protein A1 2.25865
SOWAHB sosondowah ankyrin repeat domain family member B 2.25865
LACTBL1 lactamase, beta-like 1 2.25865
RFPL2 ret finger protein-like 2 2.25865
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.25865
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.25865
BSX brain-specific homeobox 2.25865
C1ORF146 chromosome 1 open reading frame 146 2.25865
OR1L6 olfactory receptor, family 1, subfamily L, member 6 2.25865
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 2.25865
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.25865
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.25865
RLN3 relaxin 3 2.25865
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.25865
ITK IL2-inducible T-cell kinase 2.25865
BKGD beta-keto-L-gulonate decarboxylase 2.25865
TERB2 telomere repeat binding bouquet formation protein 2 2.25865
SHLD1 shieldin complex subunit 1 2.25865
MARCHF8 membrane associated ring-CH-type finger 8 2.25865
HTD2 hydroxyacyl-thioester dehydratase type 2 2.25865
VSIR V-set immunoregulatory receptor 2.25865
NECTIN4 nectin cell adhesion molecule 4 2.25865
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.25865
HAO2 hydroxyacid oxidase 2 (long chain) 2.25865
LINGO4 leucine rich repeat and Ig domain containing 4 2.25865
AVPR1B arginine vasopressin receptor 1B 2.25865
H2AC1 H2A clustered histone 1 2.25865
MEIOSIN meiosis initiator 2.25865
IHO1 interactor of HORMAD1 1 2.25865
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.25865
SPMIP10 sperm microtubule inner protein 10 2.25865
CIMAP1A ciliary microtubule associated protein 1A 2.25865
ZC3H11C zinc finger CCCH-type containing 11C 2.25865
OR8G3 olfactory receptor family 8 subfamily G member 3 (gene/pseudogene) 2.25865
PPIAP39 peptidylprolyl isomerase A pseudogene 39 2.25865
IRF2-DT IRF2 divergent transcript 2.25865
NOTCH2NLB notch 2 N-terminal like B 2.25865
SMIM43 small integral membrane protein 43 2.25865
H2AC4 H2A clustered histone 4 2.25865
ANO6 anoctamin 6 2.25865
IQCF1 IQ motif containing F1 2.25865
IL1R2 interleukin 1 receptor, type II 2.25865
PP2D1 protein phosphatase 2C-like domain containing 1 2.25865
C9 complement component 9 2.25865
PRR4 proline rich 4 (lacrimal) 2.25865
NPFF neuropeptide FF-amide peptide precursor 2.25865
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.25865
RUNX3 runt-related transcription factor 3 2.25865
SLC22A25 solute carrier family 22, member 25 2.25865
CBLN3 cerebellin 3 precursor 2.25865
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.25865
STARD6 StAR-related lipid transfer (START) domain containing 6 2.25865
LRRC71 leucine rich repeat containing 71 2.25865
COX8C cytochrome c oxidase subunit VIIIC 2.25865
FOXC1 forkhead box C1 2.25865
TTR transthyretin 2.25865
RAB3C RAB3C, member RAS oncogene family 2.25865
CMKLR1 chemerin chemokine-like receptor 1 2.25865
GPR37L1 G protein-coupled receptor 37 like 1 2.25865
CD70 CD70 molecule 2.25865
TBX10 T-box 10 2.25865
GATA2 GATA binding protein 2 2.25865
PRDM7 PR domain containing 7 2.25865
PRG4 proteoglycan 4 2.25865
SERTAD1 SERTA domain containing 1 2.25865
FXYD2 FXYD domain containing ion transport regulator 2 2.25865
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.25865
TREH trehalase (brush-border membrane glycoprotein) 2.25865
DOCK11 dedicator of cytokinesis 11 2.25865
APOC2 apolipoprotein C-II 2.25865
POU2AF1 POU class 2 associating factor 1 2.25865
C2CD4D C2 calcium-dependent domain containing 4D 2.25865
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 2.25865
HOPX HOP homeobox 2.25865
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 2.25865
RAB40AL RAB40A, member RAS oncogene family-like 2.25865
C8ORF88 chromosome 8 open reading frame 88 2.25865
AHCTF1 AT hook containing transcription factor 1 2.25865
TRADD TNFRSF1A-associated via death domain 2.25865
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.25865
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.25865
LCNL1 lipocalin-like 1 2.25865
GP5 glycoprotein V (platelet) 2.25865
ZNF541 zinc finger protein 541 2.25865
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.25865
IFITM5 interferon induced transmembrane protein 5 2.25865
SCML4 sex comb on midleg-like 4 (Drosophila) 2.25865
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.25865
UGT8 UDP glycosyltransferase 8 2.25865
CALHM1 calcium homeostasis modulator 1 2.25865
ZFP92 ZFP92 zinc finger protein 2.25865
EPHA10 EPH receptor A10 2.25865
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.25865
SLA Src-like-adaptor 2.25865
GPR150 G protein-coupled receptor 150 2.25865
SRCIN1 SRC kinase signaling inhibitor 1 2.25865
KRT39 keratin 39, type I 2.25865
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.25865
ZNF835 zinc finger protein 835 2.25865
GOLGA8M golgin A8 family, member M 2.25865
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.25865
CFH complement factor H 2.25865
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.25865
CAPSL calcyphosine-like 2.25865
CSF1R colony stimulating factor 1 receptor 2.25865
PSG3 pregnancy specific beta-1-glycoprotein 3 2.25865
C18ORF63 chromosome 18 open reading frame 63 2.25865
NT5DC4 5'-nucleotidase domain containing 4 2.25865
SMIM17 small integral membrane protein 17 2.25865
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.25865
BCL2A1 BCL2-related protein A1 2.25865
IP6K3 inositol hexakisphosphate kinase 3 2.25865
DAW1 dynein assembly factor with WDR repeat domains 1 2.25865
HIGD2B HIG1 hypoxia inducible domain family, member 2B 2.25865
SLC38A8 solute carrier family 38, member 8 2.25865
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.25865
SLC36A3 solute carrier family 36, member 3 2.25865
ACADL acyl-CoA dehydrogenase, long chain 2.25865
TEX35 testis expressed 35 2.25865
C6ORF58 chromosome 6 open reading frame 58 2.25865
SNTN sentan, cilia apical structure protein 2.25865
TEX38 testis expressed 38 2.25865
CD80 CD80 molecule 2.25865
OR11G2 olfactory receptor, family 11, subfamily G, member 2 2.25865
COL22A1 collagen, type XXII, alpha 1 2.25865
FLG2 filaggrin family member 2 2.25865
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.25865
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.25865
ST18 suppression of tumorigenicity 18, zinc finger 2.25865
ERVV-1 endogenous retrovirus group V, member 1 2.25865
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.25865
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 2.25865
CLEC2B C-type lectin domain family 2, member B 2.25865
NRGN neurogranin (protein kinase C substrate, RC3) 2.25865
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.25865
RAB7B RAB7B, member RAS oncogene family 2.25865
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 2.25865
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 2.25865
ASCL3 achaete-scute family bHLH transcription factor 3 2.25865
PDE10A phosphodiesterase 10A 2.25865
NR2E1 nuclear receptor subfamily 2, group E, member 1 2.25865
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2.25865
KRT3 keratin 3, type II 2.25865
DUSP26 dual specificity phosphatase 26 (putative) 2.25865
FZD5 frizzled class receptor 5 2.25865
SMIM22 small integral membrane protein 22 2.25865
CCL27 chemokine (C-C motif) ligand 27 2.25865
GLYATL2 glycine-N-acyltransferase-like 2 2.25865
MORC1 MORC family CW-type zinc finger 1 2.25865
PRF1 perforin 1 (pore forming protein) 2.25865
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.25865
NUTM2F NUT family member 2F 2.25865
CT55 cancer/testis antigen 55 2.25865
NOG noggin 2.25865
ZNF724 zinc finger protein 724 2.23963
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 2.23935
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 2.22791
ZNF154 zinc finger protein 154 2.21511
ANAPC7 anaphase promoting complex subunit 7 2.21482
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.20457
MRFAP1L1 Morf4 family associated protein 1-like 1 2.20457
SRPK1 SRSF protein kinase 1 2.16624
TEAD3 TEA domain family member 3 2.1596
FRMPD1 FERM and PDZ domain containing 1 2.1596
SPMIP2 sperm microtubule inner protein 2 2.1596
SIRT6 sirtuin 6 2.15533
TMEM47 transmembrane protein 47 2.15358
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.14761
DPP7 dipeptidyl-peptidase 7 2.14761
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.14761
OLFM2 olfactomedin 2 2.13937
ZMIZ2 zinc finger, MIZ-type containing 2 2.13937
DZIP1L DAZ interacting zinc finger protein 1-like 2.12959
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.11632
CNN1 calponin 1, basic, smooth muscle 2.10532
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 2.09373
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 2.08337
LRRC4B leucine rich repeat containing 4B 2.06561
PARD3B par-3 family cell polarity regulator beta 2.06561
SLF2 SMC5-SMC6 complex localization factor 2 2.04956
EPM2AIP1 EPM2A (laforin) interacting protein 1 2.02957
CAAP1 caspase activity and apoptosis inhibitor 1 2.02423
SMIM10L1 small integral membrane protein 10 like 1 2.02365
TMEM255B transmembrane protein 255B 2.00549

decreased expression

Symbol Name Standardized Value
ERFE erythroferrone -2.25865
A4GALT alpha 1,4-galactosyltransferase -2.25865
IZUMO3 IZUMO family member 3 -2.25865
E2F7 E2F transcription factor 7 -2.25865
SPINK1 serine peptidase inhibitor, Kazal type 1 -2.25865
ZDHHC7 zinc finger, DHHC-type containing 7 -2.25865
LMO3 LIM domain only 3 (rhombotin-like 2) -2.25865
SNPH syntaphilin -2.25865
SENP8 SUMO/sentrin specific peptidase family member 8 -2.25865
C9ORF152 chromosome 9 open reading frame 152 -2.25865
SH3RF3 SH3 domain containing ring finger 3 -2.25865
RGPD6 RANBP2-like and GRIP domain containing 6 -2.25865
SRP68 signal recognition particle 68kDa -2.25865
TTLL9 tubulin tyrosine ligase-like family member 9 -2.25865
TTLL1 tubulin tyrosine ligase-like family member 1 -2.25865
MCPH1 microcephalin 1 -2.25865
KCNU1 potassium channel, subfamily U, member 1 -2.25865
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -2.25865
ACOT1 acyl-CoA thioesterase 1 -2.25865
SCRG1 stimulator of chondrogenesis 1 -2.25865
ARC activity-regulated cytoskeleton-associated protein -2.25865
C2ORF72 chromosome 2 open reading frame 72 -2.25865
XKRX XK, Kell blood group complex subunit-related, X-linked -2.25865
OR52E5 olfactory receptor, family 52, subfamily E, member 5 -2.25865
AGA-DT AGA divergent transcript -2.25865
GPR83 G protein-coupled receptor 83 -2.25865
HID1 HID1 domain containing -2.25865
ALG10B ALG10B, alpha-1,2-glucosyltransferase -2.25865
CYB5A cytochrome b5 type A (microsomal) -2.25865
HSF2BP heat shock transcription factor 2 binding protein -2.25865
IVNS1ABP influenza virus NS1A binding protein -2.25865
TPTE transmembrane phosphatase with tensin homology -2.25865
ACP1 acid phosphatase 1, soluble -2.25865
CBLN1 cerebellin 1 precursor -2.25865
ERI3 ERI1 exoribonuclease family member 3 -2.25865
PCDHB10 protocadherin beta 10 -2.25865
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -2.25865
EMCN endomucin -2.25865
FGF9 fibroblast growth factor 9 -2.25865
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -2.25865
NYX nyctalopin -2.25865
FIBIN fin bud initiation factor homolog (zebrafish) -2.25865
EPX eosinophil peroxidase -2.25865
SERP2 stress-associated endoplasmic reticulum protein family member 2 -2.25865
PTGDS prostaglandin D2 synthase 21kDa (brain) -2.25865
PIANP PILR alpha associated neural protein -2.25865
EPHA7 EPH receptor A7 -2.25865
IGFBP3 insulin-like growth factor binding protein 3 -2.25865
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.25865
SMIM20 small integral membrane protein 20 -2.25865
TNNI3K TNNI3 interacting kinase -2.25865
NOTCH1 notch 1 -2.25865
PSAT1 phosphoserine aminotransferase 1 -2.25865
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) -2.25865
C22ORF31 chromosome 22 open reading frame 31 -2.25865
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.25865
ZBTB7C zinc finger and BTB domain containing 7C -2.25865
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.25865
TGM4 transglutaminase 4 -2.25865
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 -2.25865
QKI QKI, KH domain containing, RNA binding -2.24965
SMIM29 small integral membrane protein 29 -2.24282
CPNE8 copine VIII -2.23935
KIFC2 kinesin family member C2 -2.22203
PUS3 pseudouridylate synthase 3 -2.21511
MAP6D1 MAP6 domain containing 1 -2.20457
LAG3 lymphocyte-activation gene 3 -2.20457
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -2.16436
TUBB2B tubulin, beta 2B class IIb -2.1596
VAV2 vav 2 guanine nucleotide exchange factor -2.1596
SAE1 SUMO1 activating enzyme subunit 1 -2.1596
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -2.1596
MNMIP1 manchette microtubule inner protein 1 -2.1596
RBM12B RNA binding motif protein 12B -2.15599
RASL11B RAS-like, family 11, member B -2.13937
TENM2 teneurin transmembrane protein 2 -2.13525
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) -2.13456
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -2.12959
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.12867
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.12867
ECRG4 ECRG4 augurin precursor -2.11518
PIP4P2 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 -2.11383
TTLL11 tubulin tyrosine ligase-like family member 11 -2.09409
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -2.09102
ZNF226 zinc finger protein 226 -2.07959
NGEF neuronal guanine nucleotide exchange factor -2.07837
IGSF23 immunoglobulin superfamily, member 23 -2.07837
PAIP2B poly(A) binding protein interacting protein 2B -2.07544
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.07338
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -2.07174
C4ORF50 chromosome 4 open reading frame 50 -2.06561
ANKRD37 ankyrin repeat domain 37 -2.0644
C16ORF86 chromosome 16 open reading frame 86 -2.06371
BBIP1 BBSome interacting protein 1 -2.06051
DPYSL4 dihydropyrimidinase-like 4 -2.04956
APOH apolipoprotein H (beta-2-glycoprotein I) -2.03109
LRRC37A3 leucine rich repeat containing 37, member A3 -2.01062
CHRM2 cholinergic receptor, muscarinic 2 -2.00985
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -2.00549
TENM1 teneurin transmembrane protein 1 -2.00227