PSG1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description pregnancy specific beta-1-glycoprotein 1|The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009] (NCBI Entrez Gene Database, 5669)
External Link https://ncbi.nlm.nih.gov/gene/5669
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Genes

498 genes differentially expressed following the PSG1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0224053
GNAS GNAS complex locus 0.0141837
SSBP2 single-stranded DNA binding protein 2 0.0137737
KRT16 keratin 16, type I 0.0120328
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.0109077
PERP PERP, TP53 apoptosis effector 0.0106127
COG7 component of oligomeric golgi complex 7 0.0105825
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0101557
S100A9 S100 calcium binding protein A9 0.010109
TACSTD2 tumor-associated calcium signal transducer 2 0.0100959
TENT5A terminal nucleotidyltransferase 5A 0.00984826
TM4SF1 transmembrane 4 L six family member 1 0.00970778
AMDHD2 amidohydrolase domain containing 2 0.00952929
SPRR1B small proline-rich protein 1B 0.0094224
KLF4 Kruppel-like factor 4 (gut) 0.00933141
CRABP2 cellular retinoic acid binding protein 2 0.00930599
CALML3 calmodulin-like 3 0.00919934
CRISP3 cysteine-rich secretory protein 3 0.00900159
S100A8 S100 calcium binding protein A8 0.00896433
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00883717
DSP desmoplakin 0.00873528
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00873278
CXADR coxsackie virus and adenovirus receptor 0.00863213
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00860536
KRT6A keratin 6A, type II 0.0085918
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00834031
NPR3 natriuretic peptide receptor 3 0.0082684
CA2 carbonic anhydrase II 0.00823682
TPD52L1 tumor protein D52-like 1 0.00814773
S100A7 S100 calcium binding protein A7 0.00810379
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00806809
POSTN periostin, osteoblast specific factor 0.00800124
MAGEA3 melanoma antigen family A3 0.00797352
SGK1 serum/glucocorticoid regulated kinase 1 0.00796837
KLK5 kallikrein-related peptidase 5 0.00788542
MAGEA12 melanoma antigen family A12 0.00786476
PEG10 paternally expressed 10 0.00771944
CSTA cystatin A (stefin A) 0.0076368
EMX2 empty spiracles homeobox 2 0.00758644
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00757272
LGALS2 lectin, galactoside-binding, soluble, 2 0.00749752
CD59 CD59 molecule, complement regulatory protein 0.00741927
CD34 CD34 molecule 0.00737354
KRT6B keratin 6B, type II 0.00732673
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00728864
KRT17 keratin 17, type I 0.00728623
EPCAM epithelial cell adhesion molecule 0.00719975
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00718465
CLEC2B C-type lectin domain family 2, member B 0.00707938
KRT14 keratin 14, type I 0.00706759
CTSC cathepsin C 0.00704906
S100A10 S100 calcium binding protein A10 0.00702795
IFI44L interferon-induced protein 44-like 0.00698739
ZDHHC6 zinc finger, DHHC-type containing 6 0.00698676
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00696028
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00693743
QPCT glutaminyl-peptide cyclotransferase 0.0069282
DCLRE1C DNA cross-link repair 1C 0.00687757
CLCA4 chloride channel accessory 4 0.0068744
ZNF750 zinc finger protein 750 0.00686697
SPRR1A small proline-rich protein 1A 0.00685095
LAPTM4B lysosomal protein transmembrane 4 beta 0.00681461
ZDHHC11 zinc finger, DHHC-type containing 11 0.00679876
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00678408
RALB v-ral simian leukemia viral oncogene homolog B 0.00658469
CXCL10 chemokine (C-X-C motif) ligand 10 0.00654951
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00652893
DSC2 desmocollin 2 0.00651798
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00651536
KLK7 kallikrein-related peptidase 7 0.00642948
CAPRIN1 cell cycle associated protein 1 0.00639913
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00633285
CLCA2 chloride channel accessory 2 0.00632814
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.0063061
ADM adrenomedullin 0.00627527
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00626819
DSG1 desmoglein 1 0.00620627
RFTN1 raftlin, lipid raft linker 1 0.0061849
PGAM1 phosphoglycerate mutase 1 (brain) 0.00613259
LY6D lymphocyte antigen 6 complex, locus D 0.00611565
RHOBTB3 Rho-related BTB domain containing 3 0.00611362
CRCT1 cysteine-rich C-terminal 1 0.00609276
NPEPL1 aminopeptidase-like 1 0.00608547
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00606991
ATP5F1C ATP synthase F1 subunit gamma 0.00606414
CADM1 cell adhesion molecule 1 0.00606392
EXOC5 exocyst complex component 5 0.00602878
FKBP1A FK506 binding protein 1A, 12kDa 0.00602331
DUSP1 dual specificity phosphatase 1 0.00602085
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00601586
KRT15 keratin 15, type I 0.00594901
SEPP1 selenoprotein P, plasma, 1 0.00592745
CALML5 calmodulin-like 5 0.00591127
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00590262
KIAA0125 KIAA0125 0.00589011
ESRP1 epithelial splicing regulatory protein 1 0.00586955
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00586827
KLF6 Kruppel-like factor 6 0.00585753
RHCG Rh family, C glycoprotein 0.00584999
PFKP phosphofructokinase, platelet 0.00583753
RPL10 ribosomal protein L10 0.00582611
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00581468
CCNG1 cyclin G1 0.00578474
FAM198B family with sequence similarity 198, member B 0.00575948
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00575795
AHCYL1 adenosylhomocysteinase-like 1 0.00573344
FOLR1 folate receptor 1 (adult) 0.0057222
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00571398
KRT81 keratin 81, type II 0.00571142
KRT5 keratin 5, type II 0.00568711
MGAM maltase-glucoamylase 0.00567532
KYNU kynureninase 0.00565586
RANBP9 RAN binding protein 9 0.00565512
GARS1 glycyl-tRNA synthetase 1 0.00563723
CD79B CD79b molecule, immunoglobulin-associated beta 0.00563427
SYCP2 synaptonemal complex protein 2 0.00562564
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00561689
ELL2 elongation factor, RNA polymerase II, 2 0.00561484
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00561363
HIST1H2BD histone cluster 1, H2bd 0.00561234
NMD3 NMD3 ribosome export adaptor 0.00560281
EHF ets homologous factor 0.00556042
ZFP36 ZFP36 ring finger protein 0.00553981
SCEL sciellin 0.00553934
MAGEA1 melanoma antigen family A1 0.00553647
PRPF18 pre-mRNA processing factor 18 0.00553507
OXA1L oxidase (cytochrome c) assembly 1-like 0.00552016
S100A2 S100 calcium binding protein A2 0.00549573
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00549111
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00548696
RAN RAN, member RAS oncogene family 0.00548311
HBD hemoglobin, delta 0.00545951
KRT1 keratin 1, type II 0.00542798
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.00541925
CHPT1 choline phosphotransferase 1 0.00541535
LRP2 low density lipoprotein receptor-related protein 2 0.00538534
VLDLR very low density lipoprotein receptor 0.00535807
FGFR1 fibroblast growth factor receptor 1 0.00534001
SLC38A1 solute carrier family 38, member 1 0.00533531
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00532665
TMEM185B transmembrane protein 185B 0.0053186
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.00530995
YME1L1 YME1-like 1 ATPase 0.00529652
RNFT1 ring finger protein, transmembrane 1 0.00529183
E2F5 E2F transcription factor 5, p130-binding 0.00529165
EXPH5 exophilin 5 0.00528423
IVNS1ABP influenza virus NS1A binding protein 0.00523346
PODXL podocalyxin-like 0.0052298
RRAGD Ras-related GTP binding D 0.00522345
HOPX HOP homeobox 0.00521097
ABLIM1 actin binding LIM protein 1 0.00520371
GPNMB glycoprotein (transmembrane) nmb 0.00518788
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00517865
CPE carboxypeptidase E 0.00517612
RAB1A RAB1A, member RAS oncogene family 0.00517078
EIF3M eukaryotic translation initiation factor 3, subunit M 0.00512873
MUC16 mucin 16, cell surface associated 0.00512323
KIF1C kinesin family member 1C 0.00509723
FGF9 fibroblast growth factor 9 0.00507683
SPRR2B small proline-rich protein 2B 0.00507436
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00507337
PNN pinin, desmosome associated protein 0.00506438
OR7E14P olfactory receptor, family 7, subfamily E, member 14 pseudogene 0.00506217
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00502999
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00501328
CA12 carbonic anhydrase XII 0.00501261
SPAG6 sperm associated antigen 6 0.00500023
PRSS21 protease, serine, 21 (testisin) 0.00497586
SRSF1 serine/arginine-rich splicing factor 1 0.00497143
BIRC7 baculoviral IAP repeat containing 7 0.00496052
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00495631
LYPD3 LY6/PLAUR domain containing 3 0.00495384
NOP10 NOP10 ribonucleoprotein 0.00494314
MYO1B myosin IB 0.0049405
MALL mal, T-cell differentiation protein-like 0.00493449
HEBP2 heme binding protein 2 0.00491772
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa 0.00489169
ITGA6 integrin, alpha 6 0.00488637
TCTA T-cell leukemia translocation altered 0.00488446
SORT1 sortilin 1 0.00487391
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.0048647
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00486285
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00483371
UBASH3A ubiquitin associated and SH3 domain containing A 0.00483313
CXCL11 chemokine (C-X-C motif) ligand 11 0.00482892
STX7 syntaxin 7 0.0048161
SSX1 synovial sarcoma, X breakpoint 1 0.0047961
CAPN3 calpain 3, (p94) 0.00479315
MARCHF7 membrane associated ring-CH-type finger 7 0.00478927
MXI1 MAX interactor 1, dimerization protein 0.00478167
GDI2 GDP dissociation inhibitor 2 0.00478135
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00477352
APOA1 apolipoprotein A-I 0.00476286
WT1 Wilms tumor 1 0.00474312
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00472861
KL klotho 0.00472705
TLK2 tousled-like kinase 2 0.00472385
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.0047184
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.00471817
STAG3 stromal antigen 3 0.00470687
STK26 serine/threonine protein kinase 26 0.00469814
PPL periplakin 0.00468306
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.00466758
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.00466333
GSTA4 glutathione S-transferase alpha 4 0.0046577
TCL1A T-cell leukemia/lymphoma 1A 0.00465657
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00462797
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00462304
GLS glutaminase 0.00461696
EGR1 early growth response 1 0.00460619
CCN2 cellular communication network factor 2 0.00460005
COL4A5 collagen, type IV, alpha 5 0.00459337
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00459164
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0045882
MAPK6 mitogen-activated protein kinase 6 0.00458585
PKP2 plakophilin 2 0.00458389
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.00458387
C21ORF91 chromosome 21 open reading frame 91 0.00457281
PRSS23 protease, serine, 23 0.00456846
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.00456549
RUNX3 runt-related transcription factor 3 0.00456022
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00455306
ANXA3 annexin A3 0.00455262
WAC WW domain containing adaptor with coiled-coil 0.00454755
ADAM10 ADAM metallopeptidase domain 10 0.00453014
MAGEA4 melanoma antigen family A4 0.0045202
S100A14 S100 calcium binding protein A14 0.00451739
MBD4 methyl-CpG binding domain protein 4 0.00450654
RNF7 ring finger protein 7 0.00449858
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00449663
TPM4 tropomyosin 4 0.00449146
NFE2 nuclear factor, erythroid 2 0.00448528
SLC16A6 solute carrier family 16, member 6 0.00447982
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00447479
FOXE1 forkhead box E1 0.00446657
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.00446023
NELFCD negative elongation factor complex member C/D 0.00445877
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.0044525
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00445035
PON3 paraoxonase 3 0.00444447
CLDN3 claudin 3 0.00444356
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00443681
BTBD3 BTB (POZ) domain containing 3 0.00443576
AIM2 absent in melanoma 2 0.00443569
PRELID3B PRELI domain containing 3B 0.00442542
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00442231
CCL14 chemokine (C-C motif) ligand 14 0.00442178
INAVA innate immunity activator 0.00441535
ARF4 ADP-ribosylation factor 4 0.00440854

decreased expression

Symbol Name Standardized Value
METRN meteorin, glial cell differentiation regulator -0.0171123
EIF5A eukaryotic translation initiation factor 5A -0.0138814
IL7R interleukin 7 receptor -0.0126846
WDR7 WD repeat domain 7 -0.011714
ADIRF adipogenesis regulatory factor -0.0111551
TFF3 trefoil factor 3 (intestinal) -0.01057
LTBP2 latent transforming growth factor beta binding protein 2 -0.0102427
G0S2 G0/G1 switch 2 -0.0100449
CFD complement factor D (adipsin) -0.0100254
FBLN1 fibulin 1 -0.00947375
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00930413
ZBTB18 zinc finger and BTB domain containing 18 -0.00928131
GPX2 glutathione peroxidase 2 -0.00909043
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00896384
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00887795
OLFM4 olfactomedin 4 -0.00880747
C1R complement component 1, r subcomponent -0.0087753
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0086418
ZNF423 zinc finger protein 423 -0.00851293
FADS1 fatty acid desaturase 1 -0.00850122
NEFH neurofilament, heavy polypeptide -0.00840367
TXNIP thioredoxin interacting protein -0.00825542
COL14A1 collagen, type XIV, alpha 1 -0.00822145
GPX1 glutathione peroxidase 1 -0.00820488
LPAR1 lysophosphatidic acid receptor 1 -0.00818949
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00816698
MMD monocyte to macrophage differentiation-associated -0.0080358
CST3 cystatin C -0.00794177
AGR2 anterior gradient 2 -0.00792596
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00789194
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00783608
PRPF4 pre-mRNA processing factor 4 -0.00770731
CHRDL1 chordin-like 1 -0.00766583
CTSK cathepsin K -0.00766272
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00764557
NLGN4X neuroligin 4, X-linked -0.00759236
MYH11 myosin, heavy chain 11, smooth muscle -0.00751998
SRGN serglycin -0.00749683
DCXR dicarbonyl/L-xylulose reductase -0.00746184
MT1E metallothionein 1E -0.00741019
MMP1 matrix metallopeptidase 1 -0.00734658
MT1X metallothionein 1X -0.00729524
MT1M metallothionein 1M -0.00728783
SRPX sushi-repeat containing protein, X-linked -0.00726601
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00724778
AREG amphiregulin -0.00712583
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00710581
SFRP4 secreted frizzled-related protein 4 -0.00705764
RAPSN receptor-associated protein of the synapse -0.00705723
SORBS1 sorbin and SH3 domain containing 1 -0.00701674
CD93 CD93 molecule -0.00693815
THBS4 thrombospondin 4 -0.00691037
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.0068332
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00683309
SLIT2 slit homolog 2 (Drosophila) -0.00682779
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00674429
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00671616
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00671337
APOD apolipoprotein D -0.00669815
MT1H metallothionein 1H -0.00669455
ANXA6 annexin A6 -0.00667162
TMSB15A thymosin beta 15a -0.00665684
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00665641
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00663921
SYBU syntabulin (syntaxin-interacting) -0.00661402
AXL AXL receptor tyrosine kinase -0.00660301
C1ORF54 chromosome 1 open reading frame 54 -0.00653832
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -0.00652714
C4BPA complement component 4 binding protein, alpha -0.00652565
PDGFRL platelet-derived growth factor receptor-like -0.00651926
CHEK2 checkpoint kinase 2 -0.00650556
PENK proenkephalin -0.00650381
COL6A2 collagen, type VI, alpha 2 -0.00649356
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00648827
PLTP phospholipid transfer protein -0.00648347
TSPO translocator protein (18kDa) -0.00642013
AKAP12 A kinase (PRKA) anchor protein 12 -0.00641373
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00639754
SELENOW selenoprotein W -0.00639369
TOB1 transducer of ERBB2, 1 -0.00639271
STEAP3 STEAP family member 3, metalloreductase -0.00638299
OLFM1 olfactomedin 1 -0.00633231
ISYNA1 inositol-3-phosphate synthase 1 -0.00632658
PTPRD protein tyrosine phosphatase, receptor type, D -0.00627776
NTS neurotensin -0.00627221
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0062657
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00625812
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00624518
SACS sacsin molecular chaperone -0.00623253
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.006215
MDK midkine (neurite growth-promoting factor 2) -0.00620622
LPIN2 lipin 2 -0.00616382
C9ORF16 chromosome 9 open reading frame 16 -0.00616103
PDE4A phosphodiesterase 4A, cAMP-specific -0.00614708
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00613858
DIXDC1 DIX domain containing 1 -0.0060832
KDSR 3-ketodihydrosphingosine reductase -0.00607779
SPARCL1 SPARC-like 1 (hevin) -0.00605637
NFIB nuclear factor I/B -0.00603311
MAOA monoamine oxidase A -0.00602604
ICAM2 intercellular adhesion molecule 2 -0.00598922
ZBTB20 zinc finger and BTB domain containing 20 -0.0059757
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00595751
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00595532
GSPT2 G1 to S phase transition 2 -0.00594932
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.00593181
WDTC1 WD and tetratricopeptide repeats 1 -0.00591457
LEPR leptin receptor -0.00588939
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00583841
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00581792
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00578638
WDR13 WD repeat domain 13 -0.00577555
HMGB3 high mobility group box 3 -0.00575059
NANOG Nanog homeobox -0.00574905
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00574066
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00572068
PQBP1 polyglutamine binding protein 1 -0.00566759
SPON2 spondin 2, extracellular matrix protein -0.00566125
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00565794
LZTFL1 leucine zipper transcription factor-like 1 -0.00563439
PTCH1 patched 1 -0.00562904
ERLIN2 ER lipid raft associated 2 -0.00560442
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00560163
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00557901
SMC1A structural maintenance of chromosomes 1A -0.00557338
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00557023
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00556957
ADD3 adducin 3 (gamma) -0.00555209
RUNX1 runt-related transcription factor 1 -0.00554473
ZNF264 zinc finger protein 264 -0.00552685
BRD3 bromodomain containing 3 -0.00552053
CYBA cytochrome b-245, alpha polypeptide -0.00550651
SIDT2 SID1 transmembrane family, member 2 -0.00550217
FECH ferrochelatase -0.00549959
GUSB glucuronidase, beta -0.00548635
NNMT nicotinamide N-methyltransferase -0.00548343
AKAP7 A kinase (PRKA) anchor protein 7 -0.00547721
THYN1 thymocyte nuclear protein 1 -0.00547702
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00546231
LEFTY1 left-right determination factor 1 -0.00545979
REX1BD required for excision 1-B domain containing -0.00545727
CYRIA CYFIP related Rac1 interactor A -0.00544107
IL1R1 interleukin 1 receptor, type I -0.0054177
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00540967
QKI QKI, KH domain containing, RNA binding -0.00540902
CCNF cyclin F -0.00540431
MT1HL1 metallothionein 1H-like 1 -0.00539652
PRDX2 peroxiredoxin 2 -0.00539016
TECR trans-2,3-enoyl-CoA reductase -0.00538259
METTL7A methyltransferase like 7A -0.00537986
ADAM9 ADAM metallopeptidase domain 9 -0.00536961
ETV5 ets variant 5 -0.00534742
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.00532537
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00531989
KIAA0232 KIAA0232 -0.0053014
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00530096
IFI6 interferon, alpha-inducible protein 6 -0.00529512
VWF von Willebrand factor -0.00529056
PDLIM4 PDZ and LIM domain 4 -0.00527383
MT1F metallothionein 1F -0.00525716
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00523968
FLOT2 flotillin 2 -0.00522404
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00522072
NRIP3 nuclear receptor interacting protein 3 -0.00520878
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.00518546
AFF1 AF4/FMR2 family, member 1 -0.00518453
RGS5 regulator of G-protein signaling 5 -0.00512903
ZNF532 zinc finger protein 532 -0.00511928
PLAT plasminogen activator, tissue -0.00511463
SYNM synemin, intermediate filament protein -0.00510414
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.0050964
RAB29 RAB29, member RAS oncogene family -0.00509235
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.00509159
CALCA calcitonin-related polypeptide alpha -0.00508836
KIAA0930 KIAA0930 -0.00508243
SCG5 secretogranin V -0.00507926
SORD sorbitol dehydrogenase -0.00506032
F3 coagulation factor III (thromboplastin, tissue factor) -0.00503956
PLLP plasmolipin -0.0050363
CSRP1 cysteine and glycine-rich protein 1 -0.00503338
GCHFR GTP cyclohydrolase I feedback regulator -0.00502074
GPX4 glutathione peroxidase 4 -0.00501825
ANXA10 annexin A10 -0.00501522
CFI complement factor I -0.0049953
C3 complement component 3 -0.00497313
GSDME gasdermin E -0.00495709
C7 complement component 7 -0.00495707
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00494328
ATG2A autophagy related 2A -0.00493235
HELLS helicase, lymphoid-specific -0.00492443
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00491808
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -0.00489839
TMEM47 transmembrane protein 47 -0.00488505
BST2 bone marrow stromal cell antigen 2 -0.00488004
GPM6B glycoprotein M6B -0.00485766
TYROBP TYRO protein tyrosine kinase binding protein -0.00485059
CD9 CD9 molecule -0.00485035
DPYSL2 dihydropyrimidinase-like 2 -0.00484488
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00482966
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00482866
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00482695
DLG5 discs, large homolog 5 (Drosophila) -0.00482664
SMAD2 SMAD family member 2 -0.00480853
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00480822
TXNL1 thioredoxin-like 1 -0.00479774
NLRP2 NLR family, pyrin domain containing 2 -0.00479703
HCLS1 hematopoietic cell-specific Lyn substrate 1 -0.00477149
PLSCR4 phospholipid scramblase 4 -0.00476635
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00476544
EMILIN1 elastin microfibril interfacer 1 -0.00476232
PRR5 proline rich 5 (renal) -0.0047605
CNTNAP2 contactin associated protein-like 2 -0.00475029
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00475005
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.00474731
FXYD3 FXYD domain containing ion transport regulator 3 -0.00474017
GPR137B G protein-coupled receptor 137B -0.00473308
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.0047293
CARD10 caspase recruitment domain family, member 10 -0.00472715
FGL1 fibrinogen-like 1 -0.00471654
LTBP1 latent transforming growth factor beta binding protein 1 -0.00470571
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -0.00470302
PDE1A phosphodiesterase 1A, calmodulin-dependent -0.00470261
DHCR24 24-dehydrocholesterol reductase -0.00469896
FBP1 fructose-1,6-bisphosphatase 1 -0.00468168
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00467866
CFH complement factor H -0.0046747
SEC24B SEC24 family member B -0.00467151
RTN1 reticulon 1 -0.00467085
CIAPIN1 cytokine induced apoptosis inhibitor 1 -0.00466598
ALCAM activated leukocyte cell adhesion molecule -0.00466559
KIF1A kinesin family member 1A -0.00466108
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase -0.00465819
ELOVL6 ELOVL fatty acid elongase 6 -0.00465307
MAPT microtubule-associated protein tau -0.00464649
IFI30 interferon, gamma-inducible protein 30 -0.00464552
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00463518
JAG2 jagged 2 -0.00463159
GAS1 growth arrest-specific 1 -0.00462868
CLEC11A C-type lectin domain family 11, member A -0.00461843
C2CD5 C2 calcium-dependent domain containing 5 -0.00460415
COLEC12 collectin sub-family member 12 -0.00459008
C12ORF29 chromosome 12 open reading frame 29 -0.00458515
F12 coagulation factor XII (Hageman factor) -0.0045835
CEP170 centrosomal protein 170kDa -0.00457675
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00456581
PID1 phosphotyrosine interaction domain containing 1 -0.00455992
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -0.00455358
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00455313
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00454991