| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | protein tyrosine kinase 2|This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5747) |
| External Link | https://ncbi.nlm.nih.gov/gene/5747 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PTK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00998232 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00877132 |
| MAGEA3 | melanoma antigen family A3 | 0.00800473 |
| XIC | X chromosome inactivation center | 0.00776722 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00750335 |
| GOLGA8A | golgin A8 family, member A | 0.00726799 |
| GNAS | GNAS complex locus | 0.00690972 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00683647 |
| BEX1 | brain expressed, X-linked 1 | 0.00657849 |
| TSPAN8 | tetraspanin 8 | 0.00648198 |
| A2M | alpha-2-macroglobulin | 0.00632316 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00620044 |
| CTSA | cathepsin A | 0.00617127 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0058749 |
| RPN2 | ribophorin II | 0.00584991 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00582713 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00577542 |
| GOLGA8H | golgin A8 family, member H | 0.00568741 |
| S100A8 | S100 calcium binding protein A8 | 0.00559517 |
| TAC1 | tachykinin, precursor 1 | 0.00551004 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0054965 |
| LYST | lysosomal trafficking regulator | 0.0054782 |
| SLC38A10 | solute carrier family 38, member 10 | 0.00542834 |
| APOB | apolipoprotein B | 0.00540435 |
| OLFM4 | olfactomedin 4 | 0.00540169 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00540024 |
| CD38 | CD38 molecule | 0.00539686 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00538682 |
| S100A7 | S100 calcium binding protein A7 | 0.00538073 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00536536 |
| C1R | complement component 1, r subcomponent | 0.00535418 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00534111 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.0053354 |
| GUSB | glucuronidase, beta | 0.0052846 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00527226 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.00524271 |
| ATP9A | ATPase, class II, type 9A | 0.00517472 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00517189 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.0051625 |
| SV2C | synaptic vesicle glycoprotein 2C | 0.00514127 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00513686 |
| CP | ceruloplasmin (ferroxidase) | 0.00512176 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00505117 |
| PRAME | preferentially expressed antigen in melanoma | 0.00501695 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00498575 |
| C1S | complement component 1, s subcomponent | 0.00498127 |
| PMP22 | peripheral myelin protein 22 | 0.00497737 |
| CD163 | CD163 molecule | 0.00496714 |
| FGG | fibrinogen gamma chain | 0.00493985 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.004939 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0049178 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00488113 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00483635 |
| GLUL | glutamate-ammonia ligase | 0.00481496 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00481108 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00480273 |
| RND3 | Rho family GTPase 3 | 0.00479735 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00479707 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00478703 |
| ZNF512B | zinc finger protein 512B | 0.00475879 |
| TPP1 | tripeptidyl peptidase I | 0.00472501 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00472408 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00470927 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00469472 |
| SYCP2 | synaptonemal complex protein 2 | 0.00464059 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00458682 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00458311 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00456795 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00455666 |
| C7 | complement component 7 | 0.00451461 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.00447377 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00446347 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00445891 |
| IFI35 | interferon-induced protein 35 | 0.00442679 |
| PLXND1 | plexin D1 | 0.00441386 |
| DENND2D | DENN/MADD domain containing 2D | 0.00440068 |
| TLE4 | transducin-like enhancer of split 4 | 0.00437455 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.00437084 |
| C3 | complement component 3 | 0.00435533 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00435455 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00433107 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00433099 |
| EXOC7 | exocyst complex component 7 | 0.00430681 |
| TSPAN7 | tetraspanin 7 | 0.00430602 |
| ACP2 | acid phosphatase 2, lysosomal | 0.00427223 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00425678 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00424887 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.0042397 |
| COL1A2 | collagen, type I, alpha 2 | 0.00423038 |
| SLC35E2B | solute carrier family 35, member E2B | 0.00421219 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00420954 |
| LTF | lactotransferrin | 0.00420624 |
| INSR | insulin receptor | 0.00418739 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00418418 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 0.00415974 |
| PXDN | peroxidasin | 0.00415448 |
| CFB | complement factor B | 0.00413304 |
| COL3A1 | collagen, type III, alpha 1 | 0.00412362 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00411399 |
| NRCAM | neuronal cell adhesion molecule | 0.00411203 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00409672 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00409295 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00405908 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00405676 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0040491 |
| C4BPA | complement component 4 binding protein, alpha | 0.00404363 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00403443 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00403134 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.0040213 |
| MT1G | metallothionein 1G | 0.00402055 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00401703 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00400462 |
| CRP | C-reactive protein, pentraxin-related | 0.00398172 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00397962 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0039792 |
| C9 | complement component 9 | 0.0039653 |
| FSTL1 | follistatin-like 1 | 0.00396452 |
| NNMT | nicotinamide N-methyltransferase | 0.00396443 |
| OPHN1 | oligophrenin 1 | 0.00396225 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00395934 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00394981 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00394598 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00394411 |
| LUM | lumican | 0.00394083 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | 0.00393612 |
| PLIN2 | perilipin 2 | 0.00393209 |
| PLA1A | phospholipase A1 member A | 0.00391612 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00391495 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0039111 |
| WDR13 | WD repeat domain 13 | 0.00389002 |
| ADD3 | adducin 3 (gamma) | 0.0038833 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00387953 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00387275 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 | 0.00386445 |
| CANX | calnexin | 0.00384339 |
| NID1 | nidogen 1 | 0.0038428 |
| KRT5 | keratin 5, type II | 0.00384001 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00383135 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00382481 |
| ENGASE | endo-beta-N-acetylglucosaminidase | 0.00382353 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00381799 |
| MGP | matrix Gla protein | 0.00380803 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00380015 |
| TNS3 | tensin 3 | 0.00378477 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00378047 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00377979 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00376352 |
| TTR | transthyretin | 0.00376055 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00375462 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00375439 |
| RHOB | ras homolog family member B | 0.0037519 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00374802 |
| ENAH | enabled homolog (Drosophila) | 0.0037375 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00373263 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00373216 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00372875 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00372838 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.00372306 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00372285 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00371769 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00370473 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.00369714 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 0.00368657 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 0.00368511 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00367775 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00367706 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00365957 |
| XAF1 | XIAP associated factor 1 | 0.00365254 |
| C1RL | complement component 1, r subcomponent-like | 0.00365139 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00364629 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0036422 |
| STX16 | syntaxin 16 | 0.00363261 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00363247 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00362205 |
| CFD | complement factor D (adipsin) | 0.00361655 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00361468 |
| STMN2 | stathmin 2 | 0.00361198 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00360627 |
| L1CAM | L1 cell adhesion molecule | 0.00360368 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 0.00360164 |
| DMXL2 | Dmx-like 2 | 0.00360013 |
| TARP | TCR gamma alternate reading frame protein | 0.00359693 |
| CPQ | carboxypeptidase Q | 0.00359432 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00358236 |
| CYBC1 | cytochrome b-245 chaperone 1 | 0.00358111 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00357908 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.0035661 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.0035601 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.0035548 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00354746 |
| SYNM | synemin, intermediate filament protein | 0.00354493 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00352768 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | 0.00351244 |
| ORC1 | origin recognition complex, subunit 1 | 0.00351158 |
| CLCA2 | chloride channel accessory 2 | 0.00351045 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00350288 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00350232 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00349279 |
| RGS4 | regulator of G-protein signaling 4 | 0.00349197 |
| C1QA | complement component 1, q subcomponent, A chain | 0.0034899 |
| SDC1 | syndecan 1 | 0.00348661 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00348167 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00348052 |
| ANXA10 | annexin A10 | 0.00348049 |
| HLA-B | major histocompatibility complex, class I, B | 0.00347757 |
| MAGEA12 | melanoma antigen family A12 | 0.00346909 |
| NUP85 | nucleoporin 85kDa | 0.00346641 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0034563 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00345329 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0034508 |
| TRIM14 | tripartite motif containing 14 | 0.00344327 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00344242 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00343868 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00342882 |
| UBQLN2 | ubiquilin 2 | 0.0034217 |
| C1ORF216 | chromosome 1 open reading frame 216 | 0.00341933 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00340738 |
| PRAF2 | PRA1 domain family, member 2 | 0.00338969 |
| MAGED1 | melanoma antigen family D1 | 0.00338832 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00338569 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.00337879 |
| HARS2 | histidyl-tRNA synthetase 2, mitochondrial | 0.00337635 |
| KIFAP3 | kinesin-associated protein 3 | 0.00337379 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00337229 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00336911 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00336324 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00336128 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00335507 |
| VSNL1 | visinin-like 1 | 0.00335482 |
| MST1 | macrophage stimulating 1 | 0.00335325 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00335217 |
| PLPP2 | phospholipid phosphatase 2 | 0.00334777 |
| MLPH | melanophilin | 0.00334607 |
| TCTN2 | tectonic family member 2 | 0.00334537 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00334489 |
| ITGA8 | integrin, alpha 8 | 0.00332808 |
| FGF9 | fibroblast growth factor 9 | 0.00332774 |
| FMOD | fibromodulin | 0.00332769 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00332752 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00332358 |
| AHSG | alpha-2-HS-glycoprotein | 0.00331743 |
| LY75 | lymphocyte antigen 75 | 0.00330634 |
| GANAB | glucosidase, alpha; neutral AB | 0.00330399 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00330001 |
| GPI | glucose-6-phosphate isomerase | 0.003295 |
| TUBB2B | tubulin, beta 2B class IIb | 0.003276 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00327333 |
| PRPF6 | pre-mRNA processing factor 6 | 0.00327048 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00325934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTK2 | protein tyrosine kinase 2 | -0.0137169 |
| TUBB6 | tubulin, beta 6 class V | -0.0101824 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.006774 |
| E2F2 | E2F transcription factor 2 | -0.00648225 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00646238 |
| RPA3 | replication protein A3, 14kDa | -0.00645899 |
| ITM2A | integral membrane protein 2A | -0.00627641 |
| TMEM14B | transmembrane protein 14B | -0.00590542 |
| RGCC | regulator of cell cycle | -0.00572821 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00568039 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00567022 |
| TPM4 | tropomyosin 4 | -0.00564823 |
| DUSP2 | dual specificity phosphatase 2 | -0.00563359 |
| ZNF331 | zinc finger protein 331 | -0.00547185 |
| CSTA | cystatin A (stefin A) | -0.00538876 |
| SELENOT | selenoprotein T | -0.00535261 |
| ZNF586 | zinc finger protein 586 | -0.00514923 |
| MIR22HG | MIR22 host gene | -0.00500494 |
| ODC1 | ornithine decarboxylase 1 | -0.0049562 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00491374 |
| RGS10 | regulator of G-protein signaling 10 | -0.00491017 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.0048818 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00487546 |
| CREM | cAMP responsive element modulator | -0.00484778 |
| ATF3 | activating transcription factor 3 | -0.00481152 |
| RGS2 | regulator of G-protein signaling 2 | -0.00476849 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.0047501 |
| CST6 | cystatin E/M | -0.00467981 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.0046772 |
| BTG2 | BTG family, member 2 | -0.00466462 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00466028 |
| CORO1C | coronin, actin binding protein, 1C | -0.00464756 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00463064 |
| CCDC59 | coiled-coil domain containing 59 | -0.00459863 |
| COG7 | component of oligomeric golgi complex 7 | -0.00455913 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00455806 |
| SIK1 | salt-inducible kinase 1 | -0.00448865 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00447285 |
| CDCA4 | cell division cycle associated 4 | -0.00445291 |
| ESR1 | estrogen receptor 1 | -0.00444666 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00443011 |
| GOLT1B | golgi transport 1B | -0.00439838 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00439359 |
| HSPA14 | heat shock 70kDa protein 14 | -0.00439297 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00439278 |
| THBS1 | thrombospondin 1 | -0.00435951 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00433226 |
| MRPS10 | mitochondrial ribosomal protein S10 | -0.00431816 |
| ORC4 | origin recognition complex, subunit 4 | -0.00429668 |
| RIT1 | Ras-like without CAAX 1 | -0.0042901 |
| CD48 | CD48 molecule | -0.004262 |
| RNF139 | ring finger protein 139 | -0.00425371 |
| WBP5 | WW domain binding protein 5 | -0.00422346 |
| ABHD4 | abhydrolase domain containing 4 | -0.00420568 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00420355 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00419906 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.00419637 |
| TSPAN12 | tetraspanin 12 | -0.00417239 |
| ASNSD1 | asparagine synthetase domain containing 1 | -0.00416936 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00414907 |
| DSE | dermatan sulfate epimerase | -0.00414264 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00412689 |
| SUMO1 | small ubiquitin-like modifier 1 | -0.00411887 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | -0.00410372 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00409653 |
| MED21 | mediator complex subunit 21 | -0.00406272 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00405787 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00405109 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00404378 |
| CMC2 | C-x(9)-C motif containing 2 | -0.00403219 |
| MMP9 | matrix metallopeptidase 9 | -0.00399949 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00396344 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00395634 |
| LYRM4 | LYR motif containing 4 | -0.00394541 |
| STK17A | serine/threonine kinase 17a | -0.0039133 |
| MED28 | mediator complex subunit 28 | -0.00388956 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.00387563 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.00386587 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00386383 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00386283 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00386248 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00386032 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | -0.00385378 |
| LCN2 | lipocalin 2 | -0.00384599 |
| THBD | thrombomodulin | -0.0038427 |
| BTG3 | BTG family, member 3 | -0.0038393 |
| NUP54 | nucleoporin 54kDa | -0.00381359 |
| DNM1L | dynamin 1-like | -0.0038122 |
| PKP2 | plakophilin 2 | -0.00381052 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -0.00380995 |
| MAP7 | microtubule-associated protein 7 | -0.00380772 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00380346 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00379406 |
| CDC42 | cell division cycle 42 | -0.00378783 |
| CRIPT | cysteine-rich PDZ-binding protein | -0.00375952 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0037342 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00373241 |
| TSPAN6 | tetraspanin 6 | -0.00372773 |
| H2AFV | H2A histone family, member V | -0.00371408 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00370727 |
| ELOC | elongin C | -0.00370233 |
| PPP6C | protein phosphatase 6, catalytic subunit | -0.0036971 |
| WDR61 | WD repeat domain 61 | -0.00368954 |
| ZNF410 | zinc finger protein 410 | -0.00368388 |
| EVI2A | ecotropic viral integration site 2A | -0.00368352 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00368228 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0036729 |
| KLF10 | Kruppel-like factor 10 | -0.00366959 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0036692 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00366655 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.00366296 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00364998 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00363045 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00362175 |
| CLTB | clathrin, light chain B | -0.00362005 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.00361663 |
| SS18L2 | synovial sarcoma translocation gene on chromosome 18-like 2 | -0.00361633 |
| CD4 | CD4 molecule | -0.00361495 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00361463 |
| TMEM126B | transmembrane protein 126B | -0.00358691 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00358599 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00358065 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00357971 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00357219 |
| CD34 | CD34 molecule | -0.00356629 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -0.00356274 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.00356133 |
| TRAF4 | TNF receptor-associated factor 4 | -0.00356117 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00355885 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00355643 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00354937 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00354755 |
| SPP1 | secreted phosphoprotein 1 | -0.00354704 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00352845 |
| CNTN1 | contactin 1 | -0.00351918 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -0.00351878 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00351246 |
| FAM107A | family with sequence similarity 107, member A | -0.00351234 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -0.00350834 |
| KLK6 | kallikrein-related peptidase 6 | -0.00349989 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00348892 |
| CD52 | CD52 molecule | -0.00348686 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.0034842 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00348209 |
| AGO2 | argonaute RISC catalytic component 2 | -0.00347644 |
| RWDD1 | RWD domain containing 1 | -0.00347406 |
| CD83 | CD83 molecule | -0.00344872 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -0.00344756 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00344721 |
| IPO13 | importin 13 | -0.00344382 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00344032 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00342181 |
| NEBL | nebulette | -0.00341636 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00341009 |
| GPN3 | GPN-loop GTPase 3 | -0.00340993 |
| PBK | PDZ binding kinase | -0.00340381 |
| TRAPPC2L | trafficking protein particle complex 2-like | -0.0034001 |
| COMMD10 | COMM domain containing 10 | -0.00339654 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00339488 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00339276 |
| PER2 | period circadian clock 2 | -0.00338692 |
| PODXL | podocalyxin-like | -0.00338191 |
| ING3 | inhibitor of growth family, member 3 | -0.00336881 |
| FBN2 | fibrillin 2 | -0.00336731 |
| MLF1 | myeloid leukemia factor 1 | -0.00336592 |
| RPS5 | ribosomal protein S5 | -0.00336415 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00335997 |
| GLRX5 | glutaredoxin 5 | -0.00335587 |
| CA12 | carbonic anhydrase XII | -0.00333504 |
| SEPTIN10 | septin 10 | -0.00333202 |
| YEATS4 | YEATS domain containing 4 | -0.00333192 |
| VEGFA | vascular endothelial growth factor A | -0.00332821 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00332743 |
| COPS4 | COP9 signalosome subunit 4 | -0.00332243 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00331963 |
| TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | -0.0033181 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00331103 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00331026 |
| ENOPH1 | enolase-phosphatase 1 | -0.00330003 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00329535 |
| NTAQ1 | N-terminal glutamine amidase 1 | -0.00329472 |
| KRT81 | keratin 81, type II | -0.00329384 |
| IFT20 | intraflagellar transport 20 | -0.00329373 |
| NOTCH1 | notch 1 | -0.00329117 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00328429 |
| TMEM38B | transmembrane protein 38B | -0.00328128 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00327811 |
| G0S2 | G0/G1 switch 2 | -0.0032642 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00325837 |
| LGALSL | lectin, galactoside-binding-like | -0.00325748 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00325717 |
| ZNF195 | zinc finger protein 195 | -0.00325633 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | -0.00324372 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00324239 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00324211 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | -0.00323667 |
| NMB | neuromedin B | -0.00323617 |
| ISCA1 | iron-sulfur cluster assembly 1 | -0.00322574 |
| UFM1 | ubiquitin-fold modifier 1 | -0.00322331 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.00322155 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -0.00321424 |
| CYRIB | CYFIP related Rac1 interactor B | -0.00321271 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00321107 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00320959 |
| FOSL1 | FOS-like antigen 1 | -0.00320805 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.00320665 |
| DBF4 | DBF4 zinc finger | -0.00320655 |
| NPR3 | natriuretic peptide receptor 3 | -0.00320453 |
| GPX1 | glutathione peroxidase 1 | -0.00320428 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00320137 |
| FST | follistatin | -0.00319816 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00319606 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00319409 |
| PDCD10 | programmed cell death 10 | -0.00319085 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00318953 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.0031858 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00316803 |
| FERMT2 | fermitin family member 2 | -0.00316567 |
| MRPS18A | mitochondrial ribosomal protein S18A | -0.00316335 |
| IPO5 | importin 5 | -0.00316304 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | -0.00316106 |
| GUK1 | guanylate kinase 1 | -0.00315698 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00315126 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00314709 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00314619 |
| POMC | proopiomelanocortin | -0.00314193 |
| C1QBP | complement component 1, q subcomponent binding protein | -0.00314181 |
| PLEK2 | pleckstrin 2 | -0.00314004 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00313885 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.00313675 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00313449 |
| EMC8 | ER membrane protein complex subunit 8 | -0.00313446 |
| MRPL48 | mitochondrial ribosomal protein L48 | -0.00312836 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.00312778 |
| CRYL1 | crystallin, lambda 1 | -0.00312497 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00311523 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0031141 |
| TRAM1 | translocation associated membrane protein 1 | -0.00310896 |
| ARL1 | ADP-ribosylation factor-like 1 | -0.00310886 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00310637 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 | -0.00309684 |
| MDFIC | MyoD family inhibitor domain containing | -0.0030928 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00309127 |
| OSER1 | oxidative stress responsive serine-rich 1 | -0.00308747 |
| HSBP1 | heat shock factor binding protein 1 | -0.00308678 |
| STK3 | serine/threonine kinase 3 | -0.00308266 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | -0.00307759 |
| ACTL6A | actin-like 6A | -0.0030756 |
| COPS2 | COP9 signalosome subunit 2 | -0.00307286 |
| METRN | meteorin, glial cell differentiation regulator | -0.00307155 |
