PTK2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description protein tyrosine kinase 2|This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5747)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GCM_PTK2
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Genes

145 co-expressed genes for PTK2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABHD6 abhydrolase domain containing 6
ABI2 abl-interactor 2
ACTRT1 actin-related protein T1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AHCYL1 adenosylhomocysteinase-like 1
ANKRD17 ankyrin repeat domain 17
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGAP21 Rho GTPase activating protein 21
ARHGAP26 Rho GTPase activating protein 26
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATRN attractin
BACE1 beta-site APP-cleaving enzyme 1
BBS2 Bardet-Biedl syndrome 2
BTBD3 BTB (POZ) domain containing 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF198 chromosome 1 open reading frame 198
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC82 coiled-coil domain containing 82
CCDC88A coiled-coil domain containing 88A
CCDC92 coiled-coil domain containing 92
CIPC CLOCK-interacting pacemaker
CLASP2 cytoplasmic linker associated protein 2
CLCN3 chloride channel, voltage-sensitive 3
CLDND1 claudin domain containing 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDHD2 DDHD domain containing 2
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DLG1 discs, large homolog 1 (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK9 dedicator of cytokinesis 9
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DZIP3 DAZ interacting zinc finger protein 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FADS1 fatty acid desaturase 1
FAM168B family with sequence similarity 168, member B
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
FAM213A family with sequence similarity 213, member A
FAM219A family with sequence similarity 219, member A
FAM8A1 family with sequence similarity 8, member A1
FAXDC2 fatty acid hydroxylase domain containing 2
FBXO21 F-box protein 21
FBXW11 F-box and WD repeat domain containing 11
FMNL2 formin-like 2
FNIP2 folliculin interacting protein 2
FRYL FRY-like
GBA2 glucosidase, beta (bile acid) 2
GLTP glycolipid transfer protein
GOLGA7 golgin A7
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPR107 G protein-coupled receptor 107
GPRC5B G protein-coupled receptor, class C, group 5, member B
GZF1 GDNF-inducible zinc finger protein 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
KIAA0430 KIAA0430
KIAA1109 KIAA1109
KIAA1598
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1B kinesin family member 1B
KIF5C kinesin family member 5C
KLHL21 kelch-like family member 21
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LARGE like-glycosyltransferase
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEGF9 multiple EGF-like-domains 9
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MOAP1 modulator of apoptosis 1
MTMR2 myotubularin related protein 2
MYO10 myosin X
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCS1 neuronal calcium sensor 1
NDRG3 NDRG family member 3
NGRN neugrin, neurite outgrowth associated
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NLK nemo-like kinase
NOL6 nucleolar protein 6 (RNA-associated)
NPTN neuroplastin
OCIAD1 OCIA domain containing 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEG3 paternally expressed 3
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like
PKP4 plakophilin 4
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMT2 protein-O-mannosyltransferase 2
PPIG peptidylprolyl isomerase G (cyclophilin G)
PREPL prolyl endopeptidase-like
PTK2 protein tyrosine kinase 2
PTPRD protein tyrosine phosphatase, receptor type, D
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RABL2B RAB, member of RAS oncogene family-like 2B
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAN RAN, member RAS oncogene family
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RNF13 ring finger protein 13
RTN4 reticulon 4
SAP30L SAP30-like
SESN3 sestrin 3
SIK3 SIK family kinase 3
SLAIN1 SLAIN motif family, member 1
SNX27 sorting nexin family member 27
SPIRE1 spire-type actin nucleation factor 1
STAMBP STAM binding protein
TEX2 testis expressed 2
TJAP1 tight junction associated protein 1 (peripheral)
TMEM184B transmembrane protein 184B
TMEM30A transmembrane protein 30A
TMOD2 tropomodulin 2 (neuronal)
TNS2 tensin 2
TP53INP2 tumor protein p53 inducible nuclear protein 2
TRIM37 tripartite motif containing 37
TRIM8 tripartite motif containing 8
TSNAX translin-associated factor X
TTL tubulin tyrosine ligase
TTYH2 tweety family member 2
TULP4 tubby like protein 4
UBE2H ubiquitin-conjugating enzyme E2H
UFSP2 UFM1-specific peptidase 2
ULK2 unc-51 like autophagy activating kinase 2
USP32 ubiquitin specific peptidase 32
USP33 ubiquitin specific peptidase 33
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
WSB1 WD repeat and SOCS box containing 1
WSB2 WD repeat and SOCS box containing 2
YIPF5 Yip1 domain family, member 5
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZEB2 zinc finger E-box binding homeobox 2
ZER1 zyg-11 related, cell cycle regulator
ZFP14 ZFP14 zinc finger protein
ZNF536 zinc finger protein 536
ZNF565 zinc finger protein 565
ZNF710 zinc finger protein 710
ZNF84 zinc finger protein 84