PTK6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description protein tyrosine kinase 6|The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 5753)
External Link https://ncbi.nlm.nih.gov/gene/5753
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Genes

498 genes differentially expressed following the PTK6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A 0.0226047
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0156539
S100P S100 calcium binding protein P 0.0155117
GPX3 glutathione peroxidase 3 0.0144729
SLPI secretory leukocyte peptidase inhibitor 0.0144262
IFI27 interferon, alpha-inducible protein 27 0.014383
AKAP12 A kinase (PRKA) anchor protein 12 0.0132301
HSPB8 heat shock 22kDa protein 8 0.0127336
PTK2 protein tyrosine kinase 2 0.0125139
LCN2 lipocalin 2 0.0125029
RRAGD Ras-related GTP binding D 0.0124676
KLK11 kallikrein-related peptidase 11 0.0123845
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0121508
TNNT1 troponin T type 1 (skeletal, slow) 0.0119593
KLK6 kallikrein-related peptidase 6 0.0117431
CXCL8 chemokine (C-X-C motif) ligand 8 0.0116897
KLK10 kallikrein-related peptidase 10 0.0113911
RGS5 regulator of G-protein signaling 5 0.0112665
DEFB1 defensin, beta 1 0.0111917
MAL mal, T-cell differentiation protein 0.0111163
KLF6 Kruppel-like factor 6 0.0110176
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0108444
HSPB1 heat shock 27kDa protein 1 0.010819
ECM1 extracellular matrix protein 1 0.0107914
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0107613
TSPAN8 tetraspanin 8 0.0107547
ATF3 activating transcription factor 3 0.0107468
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0106679
THBS2 thrombospondin 2 0.0105591
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0104848
JUP junction plakoglobin 0.0104658
UGCG UDP-glucose ceramide glucosyltransferase 0.0104378
CSRP2 cysteine and glycine-rich protein 2 0.0102227
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0101625
AEBP1 AE binding protein 1 0.0101382
CRCT1 cysteine-rich C-terminal 1 0.0100985
C3 complement component 3 0.010058
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0100426
MSLN mesothelin 0.0100407
RHCG Rh family, C glycoprotein 0.0100173
TNNC1 troponin C type 1 (slow) 0.0100108
DNTT DNA nucleotidylexotransferase 0.00982561
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00977809
INHBA inhibin, beta A 0.00974222
NDRG1 N-myc downstream regulated 1 0.0097383
PSCA prostate stem cell antigen 0.00971169
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00968095
MID1IP1 MID1 interacting protein 1 0.00965934
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00960937
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00946203
MVP major vault protein 0.00939984
IRS2 insulin receptor substrate 2 0.00935652
CLTB clathrin, light chain B 0.00935145
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00934453
EGR1 early growth response 1 0.00922797
CSTA cystatin A (stefin A) 0.00919608
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.0091941
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00918684
ASCL1 achaete-scute family bHLH transcription factor 1 0.00911155
ANXA3 annexin A3 0.00898647
MAGEA3 melanoma antigen family A3 0.00896617
PERP PERP, TP53 apoptosis effector 0.00895579
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00894011
TRIM29 tripartite motif containing 29 0.00888764
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.008869
MYRF myelin regulatory factor 0.00872918
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00871247
ATF4 activating transcription factor 4 0.00864232
TJP2 tight junction protein 2 0.00855968
ERAP2 endoplasmic reticulum aminopeptidase 2 0.0085412
SPRR3 small proline-rich protein 3 0.00852612
KRT7 keratin 7, type II 0.00851378
SPRR2B small proline-rich protein 2B 0.00851219
JUNB jun B proto-oncogene 0.00851118
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.00849665
MX1 MX dynamin-like GTPase 1 0.00842056
SCEL sciellin 0.00841259
GSTP1 glutathione S-transferase pi 1 0.00838571
GLTP glycolipid transfer protein 0.00837599
BMP2 bone morphogenetic protein 2 0.00836624
BAG3 BCL2-associated athanogene 3 0.00836231
TRIM16 tripartite motif containing 16 0.00832341
PCNA proliferating cell nuclear antigen 0.00832218
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00828442
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00828092
TGM1 transglutaminase 1 0.00824859
CRYAB crystallin, alpha B 0.008248
DDIT3 DNA-damage-inducible transcript 3 0.00821846
CRISP3 cysteine-rich secretory protein 3 0.00820001
PEG10 paternally expressed 10 0.00819665
TTN titin 0.00817465
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00813496
NRCAM neuronal cell adhesion molecule 0.00812939
GADD45B growth arrest and DNA-damage-inducible, beta 0.00812699
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00807875
IL1RN interleukin 1 receptor antagonist 0.00807132
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00804318
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00804043
S100A9 S100 calcium binding protein A9 0.00803864
IL6 interleukin 6 0.00799745
KLK7 kallikrein-related peptidase 7 0.00798716
PDZD2 PDZ domain containing 2 0.00797169
GAB2 GRB2-associated binding protein 2 0.00796172
AK1 adenylate kinase 1 0.00793958
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.00793652
S100A7 S100 calcium binding protein A7 0.00785237
CXCL2 chemokine (C-X-C motif) ligand 2 0.0078396
CALB1 calbindin 1, 28kDa 0.00781302
PLAT plasminogen activator, tissue 0.00781157
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0078008
LPIN1 lipin 1 0.00778565
TNIP1 TNFAIP3 interacting protein 1 0.00777692
RUNX1 runt-related transcription factor 1 0.00777278
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00776383
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00763391
SGCE sarcoglycan, epsilon 0.00763369
TRIB3 tribbles pseudokinase 3 0.00763184
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00761853
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00761819
FOLR1 folate receptor 1 (adult) 0.00759853
HMOX1 heme oxygenase 1 0.00757052
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00756489
SPRR1A small proline-rich protein 1A 0.00755588
PALLD palladin, cytoskeletal associated protein 0.00753702
KLK8 kallikrein-related peptidase 8 0.00753493
TENT5A terminal nucleotidyltransferase 5A 0.00750135
KRT14 keratin 14, type I 0.00749153
SRPX sushi-repeat containing protein, X-linked 0.00748962
PI3 peptidase inhibitor 3, skin-derived 0.00748956
IFRD1 interferon-related developmental regulator 1 0.00748326
KLHL24 kelch-like family member 24 0.00747513
PITX1 paired-like homeodomain 1 0.00747476
KLK5 kallikrein-related peptidase 5 0.0074723
KLHL41 kelch-like family member 41 0.00743416
MUC16 mucin 16, cell surface associated 0.00743394
LOC105375355 uroplakin-3b 0.00738686
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0073742
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.00737123
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00733197
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00732259
FYN FYN proto-oncogene, Src family tyrosine kinase 0.00726942
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00726386
NOP56 NOP56 ribonucleoprotein 0.00725866
CXCL5 chemokine (C-X-C motif) ligand 5 0.00725824
SORBS3 sorbin and SH3 domain containing 3 0.00724808
CLEC11A C-type lectin domain family 11, member A 0.00724693
IRF1 interferon regulatory factor 1 0.0072193
ZBED2 zinc finger, BED-type containing 2 0.00720713
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00719382
FRMD4B FERM domain containing 4B 0.00719154
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00714047
SPRR1B small proline-rich protein 1B 0.007125
FOSL2 FOS-like antigen 2 0.0070943
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.00707875
PNMA2 paraneoplastic Ma antigen 2 0.00706966
MX2 MX dynamin-like GTPase 2 0.00706255
THBS4 thrombospondin 4 0.0070275
TCF4 transcription factor 4 0.00702188
STK24 serine/threonine kinase 24 0.00698153
PXDN peroxidasin 0.00697367
IER3 immediate early response 3 0.00695287
TDRD7 tudor domain containing 7 0.00694414
PODXL podocalyxin-like 0.00693223
ZNF83 zinc finger protein 83 0.00693094
VPREB1 pre-B lymphocyte 1 0.00692432
RFTN1 raftlin, lipid raft linker 1 0.00692063
BAMBI BMP and activin membrane-bound inhibitor 0.00690452
AREG amphiregulin 0.00688675
TMEM176B transmembrane protein 176B 0.00687464
FOXO1 forkhead box O1 0.00684047
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00681292
SOX4 SRY (sex determining region Y)-box 4 0.00680151
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00680104
C1S complement component 1, s subcomponent 0.00679281
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.0067443
IL1A interleukin 1, alpha 0.00673651
GRWD1 glutamate-rich WD repeat containing 1 0.00672679
IFI44L interferon-induced protein 44-like 0.00671671
CKM creatine kinase, muscle 0.00671207
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00667242
STK10 serine/threonine kinase 10 0.00666748
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00666568
TACSTD2 tumor-associated calcium signal transducer 2 0.00665536
AMDHD2 amidohydrolase domain containing 2 0.00661588
MN1 meningioma (disrupted in balanced translocation) 1 0.00660482
PYCARD PYD and CARD domain containing 0.0065607
RCAN1 regulator of calcineurin 1 0.00653606
KLF4 Kruppel-like factor 4 (gut) 0.00653144
ABLIM1 actin binding LIM protein 1 0.00651882
ANKRD10 ankyrin repeat domain 10 0.00651525
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.00650613
FASTKD5 FAST kinase domains 5 0.00648856
PEG3 paternally expressed 3 0.00648316
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00648274
EFNA1 ephrin-A1 0.00646827
DMTF1 cyclin D binding myb-like transcription factor 1 0.00645416
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00645202
STON1 stonin 1 0.00645104
ISG15 ISG15 ubiquitin-like modifier 0.00643583
DCN decorin 0.00641913
FN1 fibronectin 1 0.00641264
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00639221
TCTA T-cell leukemia translocation altered 0.00639179
MYOF myoferlin 0.00638759
HLX H2.0-like homeobox 0.00638462
C10ORF10 chromosome 10 open reading frame 10 0.00638043
DPYSL2 dihydropyrimidinase-like 2 0.00637344
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00636544
LMCD1 LIM and cysteine-rich domains 1 0.00636179
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00635463
HIST1H2BD histone cluster 1, H2bd 0.00635185
GRN granulin 0.00634943
GYPC glycophorin C (Gerbich blood group) 0.00634934
RHOF ras homolog family member F (in filopodia) 0.00634409
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00633282
LAMA2 laminin, alpha 2 0.00631371
SMPX small muscle protein, X-linked 0.0062431
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00623445
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00621688
HIST1H2BK histone cluster 1, H2bk 0.0062148
SIK1 salt-inducible kinase 1 0.00620475
DDIT4 DNA-damage-inducible transcript 4 0.0061931
MAGEA4 melanoma antigen family A4 0.00616729
TPPP3 tubulin polymerization-promoting protein family member 3 0.00616042
ISG20 interferon stimulated exonuclease gene 20kDa 0.0061455
JAM3 junctional adhesion molecule 3 0.0061135
STX3 syntaxin 3 0.0061078
MELK maternal embryonic leucine zipper kinase 0.00608157
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00607837
KLK13 kallikrein-related peptidase 13 0.00607824
BEX4 brain expressed, X-linked 4 0.00606804
DAPK1 death-associated protein kinase 1 0.00605449
MYOT myotilin 0.00605346
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00603883
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00603812
IL15 interleukin 15 0.00603604
FILIP1L filamin A interacting protein 1-like 0.00601887
ARG1 arginase 1 0.00600895
PDE4DIP phosphodiesterase 4D interacting protein 0.00599872
SINHCAF SIN3-HDAC complex associated factor 0.00599377
GCH1 GTP cyclohydrolase 1 0.00598984
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00598055
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 0.00597587
RABAC1 Rab acceptor 1 (prenylated) 0.005975
PLLP plasmolipin 0.00597316
TUFT1 tuftelin 1 0.00597035
TPST1 tyrosylprotein sulfotransferase 1 0.00596453
ESRP1 epithelial splicing regulatory protein 1 0.00595103
HEATR1 HEAT repeat containing 1 0.00595046

decreased expression

Symbol Name Standardized Value
OLFM4 olfactomedin 4 -0.0156364
TXNDC9 thioredoxin domain containing 9 -0.0151395
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0146069
CHKB choline kinase beta -0.0133149
CD320 CD320 molecule -0.0132983
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0121988
CPA3 carboxypeptidase A3 (mast cell) -0.0119886
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0118809
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0115891
ANPEP alanyl (membrane) aminopeptidase -0.0114745
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0114237
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.0113968
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0112138
KIF20A kinesin family member 20A -0.0111157
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.0108852
FABP1 fatty acid binding protein 1, liver -0.01069
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0106881
SELENBP1 selenium binding protein 1 -0.010548
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.0104702
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0104589
JCHAIN joining chain of multimeric IgA and IgM -0.0102721
TRPS1 trichorhinophalangeal syndrome I -0.010257
DEFA5 defensin, alpha 5, Paneth cell-specific -0.0100592
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.010038
PCP4 Purkinje cell protein 4 -0.00997316
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00982707
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00981005
CLCA1 chloride channel accessory 1 -0.00972188
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0095973
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.00945787
NTS neurotensin -0.0094343
C1ORF115 chromosome 1 open reading frame 115 -0.00939505
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00938462
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.00918588
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00917741
NAV2 neuron navigator 2 -0.00896843
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00895295
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00894385
FGFR2 fibroblast growth factor receptor 2 -0.00889184
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00885276
CCNE2 cyclin E2 -0.00872089
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.0087066
HAT1 histone acetyltransferase 1 -0.00856686
SFTPA2 surfactant protein A2 -0.00854972
SUB1 SUB1 homolog (S. cerevisiae) -0.00849561
MMP12 matrix metallopeptidase 12 -0.00843996
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.00840821
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00835347
PID1 phosphotyrosine interaction domain containing 1 -0.00834366
DUOX2 dual oxidase 2 -0.00829461
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00825085
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00822782
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00820323
SFTPB surfactant protein B -0.00816849
SLC2A4RG SLC2A4 regulator -0.00815625
MCOLN1 mucolipin 1 -0.00812831
NMU neuromedin U -0.00803563
GPA33 glycoprotein A33 (transmembrane) -0.00800595
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00794895
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00794722
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00794061
A2M alpha-2-macroglobulin -0.00790843
TNC tenascin C -0.00789881
IGFBP5 insulin-like growth factor binding protein 5 -0.00789658
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00787982
C4BPA complement component 4 binding protein, alpha -0.00785905
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00784034
CADPS2 Ca++-dependent secretion activator 2 -0.0077412
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -0.00772204
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -0.00768925
ADORA2B adenosine A2b receptor -0.00766545
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00766112
ELOVL5 ELOVL fatty acid elongase 5 -0.00761208
FCGBP Fc fragment of IgG binding protein -0.007594
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00758865
MAOA monoamine oxidase A -0.00757919
HMGB3 high mobility group box 3 -0.0075669
METTL7A methyltransferase like 7A -0.00755245
DCXR dicarbonyl/L-xylulose reductase -0.0075422
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00751631
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00751616
PBX1 pre-B-cell leukemia homeobox 1 -0.00749376
NRGN neurogranin (protein kinase C substrate, RC3) -0.00748841
TMEM14B transmembrane protein 14B -0.00746173
ZG16 zymogen granule protein 16 -0.00739689
COL3A1 collagen, type III, alpha 1 -0.00736741
GCLC glutamate-cysteine ligase, catalytic subunit -0.00734864
COL1A2 collagen, type I, alpha 2 -0.00733572
ADAMDEC1 ADAM-like, decysin 1 -0.00732402
HNMT histamine N-methyltransferase -0.00732004
RTN1 reticulon 1 -0.00730498
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00728167
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) -0.00725121
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00724737
REG3A regenerating islet-derived 3 alpha -0.00724417
WFDC1 WAP four-disulfide core domain 1 -0.00723499
TPSAB1 tryptase alpha/beta 1 -0.00720671
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00718562
TMEM131 transmembrane protein 131 -0.00717576
SRGN serglycin -0.00716774
HCRT hypocretin (orexin) neuropeptide precursor -0.00713927
FASN fatty acid synthase -0.00708168
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00706596
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00704805
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00702683
NELL2 NEL-like 2 (chicken) -0.00702616
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00701681
GLUL glutamate-ammonia ligase -0.00701082
BTBD2 BTB (POZ) domain containing 2 -0.00700556
MMP7 matrix metallopeptidase 7 -0.00697899
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00696686
ACAT2 acetyl-CoA acetyltransferase 2 -0.00695596
ATP11B ATPase, class VI, type 11B -0.00693637
OIP5 Opa interacting protein 5 -0.00692875
IL2RB interleukin 2 receptor, beta -0.00691907
REG1B regenerating islet-derived 1 beta -0.00691156
MEX3D mex-3 RNA binding family member D -0.00690987
ADAM9 ADAM metallopeptidase domain 9 -0.00689865
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00685859
NDUFA4 NDUFA4, mitochondrial complex associated -0.00684728
CNN3 calponin 3, acidic -0.00682501
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -0.00681676
KYAT3 kynurenine aminotransferase 3 -0.00681101
XCL1 chemokine (C motif) ligand 1 -0.00680708
DMBT1 deleted in malignant brain tumors 1 -0.0067631
RBM8A RNA binding motif protein 8A -0.00673706
NEK2 NIMA-related kinase 2 -0.00672118
DNASE1L3 deoxyribonuclease I-like 3 -0.00670395
POSTN periostin, osteoblast specific factor -0.00669397
ZMIZ2 zinc finger, MIZ-type containing 2 -0.00669188
MEST mesoderm specific transcript -0.00668408
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00661955
SIRT3 sirtuin 3 -0.00661786
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00661394
SRP9 signal recognition particle 9kDa -0.00660869
HYOU1 hypoxia up-regulated 1 -0.00660017
PIGR polymeric immunoglobulin receptor -0.00659844
MSH2 mutS homolog 2 -0.00657708
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00654791
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00654284
CD38 CD38 molecule -0.00652118
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00652044
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00652028
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00651432
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00651088
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.00650732
ANGEL2 angel homolog 2 (Drosophila) -0.00648082
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00647851
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -0.00645744
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -0.00645448
SEC23A Sec23 homolog A (S. cerevisiae) -0.00644964
COL4A5 collagen, type IV, alpha 5 -0.00644891
LYZ lysozyme -0.00644469
PARM1 prostate androgen-regulated mucin-like protein 1 -0.00644403
MT1F metallothionein 1F -0.00643181
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00642858
PRF1 perforin 1 (pore forming protein) -0.00640256
CADM1 cell adhesion molecule 1 -0.00639844
LEFTY1 left-right determination factor 1 -0.0063774
TBX3 T-box 3 -0.0063503
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00632365
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.0063152
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00630459
EXPH5 exophilin 5 -0.00630354
PDZRN3 PDZ domain containing ring finger 3 -0.00629905
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00629471
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00627523
MIA3 melanoma inhibitory activity family, member 3 -0.00627119
NPM3 nucleophosmin/nucleoplasmin 3 -0.00625857
THAP12 THAP domain containing 12 -0.00624741
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00624707
OLFM1 olfactomedin 1 -0.00624598
PBLD phenazine biosynthesis-like protein domain containing -0.00623627
XK X-linked Kx blood group -0.00623426
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -0.00622147
NIPSNAP2 nipsnap homolog 2 -0.00621958
GPM6B glycoprotein M6B -0.00620994
CYBRD1 cytochrome b reductase 1 -0.00619593
HLA-DOB major histocompatibility complex, class II, DO beta -0.0061707
FAM189A2 family with sequence similarity 189, member A2 -0.00615744
SV2A synaptic vesicle glycoprotein 2A -0.00614917
TYROBP TYRO protein tyrosine kinase binding protein -0.00614611
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.00614449
EFHD1 EF-hand domain family, member D1 -0.00613743
SDC2 syndecan 2 -0.00613372
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00613363
SPTSSA serine palmitoyltransferase, small subunit A -0.0061318
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00609651
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00609326
CALML4 calmodulin-like 4 -0.00609216
TTC19 tetratricopeptide repeat domain 19 -0.00606517
ACP5 acid phosphatase 5, tartrate resistant -0.00606088
NBPF10 neuroblastoma breakpoint family, member 10 -0.00602838
MT1M metallothionein 1M -0.006017
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.0060012
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -0.00599603
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00598534
LRRC8B leucine rich repeat containing 8 family, member B -0.00596514
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.00596401
ZNF239 zinc finger protein 239 -0.00596052
SFTPC surfactant protein C -0.0059588
NDNF neuron-derived neurotrophic factor -0.00594632
FZD5 frizzled class receptor 5 -0.00593365
TMSB15A thymosin beta 15a -0.0059212
VSNL1 visinin-like 1 -0.00591992
CD96 CD96 molecule -0.00591108
MTCH2 mitochondrial carrier 2 -0.00590869
PIMREG PICALM interacting mitotic regulator -0.00590614
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00589525
SELENOF selenoprotein F -0.00589355
MPZL2 myelin protein zero-like 2 -0.00588742
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.00588483
TGFBI transforming growth factor, beta-induced, 68kDa -0.00587916
NUSAP1 nucleolar and spindle associated protein 1 -0.00587747
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00586735
PRC1 protein regulator of cytokinesis 1 -0.00586293
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -0.00585784
GTSE1 G-2 and S-phase expressed 1 -0.00585711
NCAN neurocan -0.0058391
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00583269
HSPB11 heat shock protein family B (small), member 11 -0.00582836
GSTT1 glutathione S-transferase theta 1 -0.00582705
GPM6A glycoprotein M6A -0.00581936
CD8A CD8a molecule -0.00581915
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00581596
MT1G metallothionein 1G -0.00581502
SGSM2 small G protein signaling modulator 2 -0.0057937
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00579157
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00579082
MDFIC MyoD family inhibitor domain containing -0.00578693
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00578049
TTC38 tetratricopeptide repeat domain 38 -0.00577203
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00575697
DEAF1 DEAF1 transcription factor -0.00575665
FRZB frizzled-related protein -0.00575452
ENO2 enolase 2 (gamma, neuronal) -0.00575173
TENT4A terminal nucleotidyltransferase 4A -0.00574375
UGDH UDP-glucose 6-dehydrogenase -0.00574187
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.00573483
VEGFA vascular endothelial growth factor A -0.00572437
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -0.00571644
XYLT1 xylosyltransferase I -0.00571087
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0057098
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00570037
SDF4 stromal cell derived factor 4 -0.00570026
CDC7 cell division cycle 7 -0.0056984
FOXA1 forkhead box A1 -0.00568348
TIPRL TOR signaling pathway regulator -0.00567366
EPHA4 EPH receptor A4 -0.00566075