PTK6 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description protein tyrosine kinase 6|The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 5753)
External Link http://www.ncbi.nlm.nih.gov/gene/5753
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Genes

10 substrates of the kinase PTK6 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP5 Rho GTPase activating protein 5
BCAR1 breast cancer anti-estrogen resistance 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
PTK6 protein tyrosine kinase 6
PXN paxillin
STAP2 signal transducing adaptor family member 2
STAT5B signal transducer and activator of transcription 5B