PTN Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description pleiotrophin| (NCBI Entrez Gene Database, 5764)
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Genes

366 genes differentially expressed following the PTN gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
HBA2 hemoglobin, alpha 2 2.87933
PRODH2 proline dehydrogenase (oxidase) 2 2.87933
RIMBP2 RIMS binding protein 2 2.87933
CCNB3 cyclin B3 2.87933
MYBPC3 myosin binding protein C, cardiac 2.87933
DRICH1 aspartate-rich 1 2.87933
CCDC68 coiled-coil domain containing 68 2.87933
GJB3 gap junction protein, beta 3, 31kDa 2.87933
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.87933
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.87933
CD300A CD300a molecule 2.87933
OLIG1 oligodendrocyte transcription factor 1 2.87933
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.87933
PRICKLE4 prickle homolog 4 (Drosophila) 2.87933
IGFL3 IGF-like family member 3 2.87933
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.87933
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.87933
GJA5 gap junction protein, alpha 5, 40kDa 2.87933
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 2.87933
CCKAR cholecystokinin A receptor 2.87933
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.87933
INHBC inhibin, beta C 2.87933
TXLNB taxilin beta 2.87933
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.87933
NPAP1 nuclear pore associated protein 1 2.87933
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.87933
CTRC chymotrypsin C (caldecrin) 2.87933
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.87933
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.87933
SPMIP11 sperm microtubule inner protein 11 2.87933
LONRF2 LON peptidase N-terminal domain and ring finger 2 2.87933
TMCO5A transmembrane and coiled-coil domains 5A 2.87933
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.87933
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.87933
MYO1A myosin IA 2.87933
CLCN1 chloride channel, voltage-sensitive 1 2.87933
CPLX3 complexin 3 2.87933
HMX3 H6 family homeobox 3 2.87933
TPPP tubulin polymerization promoting protein 2.87933
LOC105378220 macrophage receptor MARCO-like 2.87933
NWD2 NACHT and WD repeat domain containing 2 2.87933
RLN1 relaxin 1 2.87933
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.87933
SSTR3 somatostatin receptor 3 2.87933
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 2.87933
PBOV1 prostate and breast cancer overexpressed 1 2.87933
HCRTR2 hypocretin (orexin) receptor 2 2.87933
SP7 Sp7 transcription factor 2.87933
ADGB androglobin 2.87933
FSCN2 fascin actin-bundling protein 2, retinal 2.87933
TMEM72 transmembrane protein 72 2.87933
TNS4 tensin 4 2.87933
LCN10 lipocalin 10 2.87933
SPNS2 spinster homolog 2 (Drosophila) 2.87933
UMODL1 uromodulin-like 1 2.87933
NWD1 NACHT and WD repeat domain containing 1 2.87933
SPEM3 SPEM family member 3 2.87933
CCDC187 coiled-coil domain containing 187 2.87933
NIBAN3 niban apoptosis regulator 3 2.87933
ANGPTL8 angiopoietin like 8 2.87933
CCDC9B coiled-coil domain containing 9B 2.87933
PNMA8B PNMA family member 8B 2.87933
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.87933
HDGFL2 HDGF like 2 2.87933
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.87933
GIPC3 GIPC PDZ domain containing family, member 3 2.87933
GBP6 guanylate binding protein family, member 6 2.87933
C3AR1 complement component 3a receptor 1 2.87933
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.87933
TAFA3 TAFA chemokine like family member 3 2.87933
SOFU1 sperm-oocyte fusion factor 1 2.87933
STRIT1 small transmembrane regulator of ion transport 1 2.87933
LINC02268 long intergenic non-protein coding RNA 2268 2.87933
LRRC8C-DT LRRC8C divergent transcript 2.87933
CPNE8-AS1 CPNE8 antisense RNA 1 2.87933
REELD1 reeler domain containing 1 2.87933
TMDD1 transmembrane and death domain 1 2.87933
H3C3 H3 clustered histone 3 2.87933
TMEM272 transmembrane protein 272 2.87933
IQCN IQ motif containing N 2.87933
SEPTIN12 septin 12 2.87933
DEFB131B defensin beta 131B 2.87933
GARIN1A golgi associated RAB2 interactor 1A 2.87933
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.87933
C9ORF43 chromosome 9 open reading frame 43 2.87933
ZIC4 Zic family member 4 2.87933
CXCL16 chemokine (C-X-C motif) ligand 16 2.87933
MSX2 msh homeobox 2 2.87933
CATSPER3 cation channel, sperm associated 3 2.87933
LDHAL6B lactate dehydrogenase A-like 6B 2.87933
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.87933
IRF8 interferon regulatory factor 8 2.87933
PRB3 proline-rich protein BstNI subfamily 3 2.87933
KLHL33 kelch-like family member 33 2.87933
ZNF436 zinc finger protein 436 2.87933
CPED1 cadherin-like and PC-esterase domain containing 1 2.87933
FPR2 formyl peptide receptor 2 2.87933
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.87933
SCRT2 scratch family zinc finger 2 2.87933
FCMR Fc fragment of IgM receptor 2.87933
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.87933
TBX10 T-box 10 2.87933
CSAG3 CSAG family, member 3 2.87933
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.87933
PNPLA1 patatin-like phospholipase domain containing 1 2.87933
ARMC12 armadillo repeat containing 12 2.87933
TACR2 tachykinin receptor 2 2.87933
EXOC3L1 exocyst complex component 3-like 1 2.87933
NPFF neuropeptide FF-amide peptide precursor 2.87933
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 2.87933
IL5 interleukin 5 2.87933
PRB1 proline-rich protein BstNI subfamily 1 2.87933
TRIM29 tripartite motif containing 29 2.87933
CST1 cystatin SN 2.87933
MAMDC4 MAM domain containing 4 2.87933
ADORA3 adenosine A3 receptor 2.87933
HHLA2 HERV-H LTR-associating 2 2.87933
C9ORF64 chromosome 9 open reading frame 64 2.87933
SCML4 sex comb on midleg-like 4 (Drosophila) 2.87933
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.87933
WFDC6 WAP four-disulfide core domain 6 2.87933
FBP1 fructose-1,6-bisphosphatase 1 2.87933
NPFFR1 neuropeptide FF receptor 1 2.87933
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.87933
CDC20B cell division cycle 20B 2.87933
C18ORF63 chromosome 18 open reading frame 63 2.87933
PDCD1 programmed cell death 1 2.87933
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.87933
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.87933
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 2.87933
LRRC32 leucine rich repeat containing 32 2.87933
KLHL1 kelch-like family member 1 2.87933
EBF2 early B-cell factor 2 2.87933
TMEM132D transmembrane protein 132D 2.87933
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.87933
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.87933
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.87933
MAB21L2 mab-21-like 2 (C. elegans) 2.87933
MAB21L1 mab-21-like 1 (C. elegans) 2.87933
BCL2L15 BCL2-like 15 2.87933
IGSF10 immunoglobulin superfamily, member 10 2.87933
NMBR neuromedin B receptor 2.87933
KLHDC1 kelch domain containing 1 2.87933
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.87933
CLEC18B C-type lectin domain family 18, member B 2.87933
CXORF58 chromosome X open reading frame 58 2.87933
SFTA2 surfactant associated 2 2.87933
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.87933
GOLGA8N golgin A8 family, member N 2.87933
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.87933
DLX5 distal-less homeobox 5 2.87933
DMRT1 doublesex and mab-3 related transcription factor 1 2.87933
CYS1 cystin 1 2.87933
TRIM50 tripartite motif containing 50 2.87933
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.87933
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.87933
HRCT1 histidine rich carboxyl terminus 1 2.87933
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.87933
ZNF843 zinc finger protein 843 2.87933
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.87933
HK3 hexokinase 3 (white cell) 2.87933
EPHA10 EPH receptor A10 2.87933
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.87933
ANKRD62 ankyrin repeat domain 62 2.87933
FZD1 frizzled class receptor 1 2.87933
PADI1 peptidyl arginine deiminase, type I 2.87933
MEIG1 meiosis/spermiogenesis associated 1 2.87933
TSKS testis-specific serine kinase substrate 2.87933
GRAP2 GRB2-related adaptor protein 2 2.87933
OTX1 orthodenticle homeobox 1 2.87933
IL33 interleukin 33 2.87933
FOXP3 forkhead box P3 2.87933
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2.87933
PF4V1 platelet factor 4 variant 1 2.87933
TMEM156 transmembrane protein 156 2.87933
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 2.87933
ZC2HC1B zinc finger, C2HC-type containing 1B 2.87933
SDSL serine dehydratase-like 2.87933
TSSK1B testis-specific serine kinase 1B 2.87933
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.87933
NRGN neurogranin (protein kinase C substrate, RC3) 2.87933
SLC51B solute carrier family 51, beta subunit 2.87933
C5ORF47 chromosome 5 open reading frame 47 2.87933
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.87933
TTC36 tetratricopeptide repeat domain 36 2.87933
METTL21C methyltransferase like 21C 2.87933
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.87933
ACVRL1 activin A receptor type II-like 1 2.87933
DEFB134 defensin, beta 134 2.87933
SOST sclerostin 2.87933
LPAR5 lysophosphatidic acid receptor 5 2.87933
NLRP9 NLR family, pyrin domain containing 9 2.87933
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.87933
TMEM86A transmembrane protein 86A 2.87933
POU5F1 POU class 5 homeobox 1 2.86155
TOR1A torsin family 1, member A (torsin A) 2.84527
ATXN1 ataxin 1 2.83772
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 2.81182
INHBE inhibin, beta E 2.81182
RAP1B RAP1B, member of RAS oncogene family 2.80599
ELOVL1 ELOVL fatty acid elongase 1 2.80419
SENP1 SUMO1/sentrin specific peptidase 1 2.75645
ACD adrenocortical dysplasia homolog (mouse) 2.72292
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 2.70643
NOVA1 neuro-oncological ventral antigen 1 2.68813
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.638
TESK2 testis-specific kinase 2 2.54937
NME9 NME/NM23 family member 9 2.52956
NRSN1 neurensin 1 2.51722
PRELP proline/arginine-rich end leucine-rich repeat protein 2.51722
FLNB filamin B, beta 2.46945
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) 2.46569
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 2.45
PAPLN papilin, proteoglycan-like sulfated glycoprotein 2.44765
ELOVL6 ELOVL fatty acid elongase 6 2.4475
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.356
KRT7 keratin 7, type II 2.33507
VIPR1 vasoactive intestinal peptide receptor 1 2.31754
KLF6 Kruppel-like factor 6 2.31303
AASS aminoadipate-semialdehyde synthase 2.28806
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 2.28493
APOO apolipoprotein O 2.28218
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.27226
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.24672
OTX2 orthodenticle homeobox 2 2.23488
PGAP3 post-GPI attachment to proteins 3 2.23488
RP9 retinitis pigmentosa 9 (autosomal dominant) 2.23055
ABHD2 abhydrolase domain containing 2 2.21861
TK2 thymidine kinase 2, mitochondrial 2.20805
RREB1 ras responsive element binding protein 1 2.19642
RNF149 ring finger protein 149 2.19642
SNX18 sorting nexin 18 2.19464
RPL36AL ribosomal protein L36a-like 2.18334
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.18268
SIX4 SIX homeobox 4 2.17466
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 2.14433
EEF1AKMT2 EEF1A lysine methyltransferase 2 2.1277
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.0891
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) 2.07596
TRIM25 tripartite motif containing 25 2.06485
RLF rearranged L-myc fusion 2.05543
LINGO1 leucine rich repeat and Ig domain containing 1 2.0504
MYCBP MYC binding protein 2.01994
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.01927
TMTC2 transmembrane and tetratricopeptide repeat containing 2 2.01927
MRPL48 mitochondrial ribosomal protein L48 2.01054
DBF4 DBF4 zinc finger 2.00852
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 2.00814
BAG1 BCL2-associated athanogene 2.00814
KDR kinase insert domain receptor 2.00814
YEATS4 YEATS domain containing 4 2.002

decreased expression

Symbol Name Standardized Value
TBC1D3L TBC1 domain family, member 3L -2.87933
CCL2 chemokine (C-C motif) ligand 2 -2.87933
MUC5B mucin 5B, oligomeric mucus/gel-forming -2.87933
GFAP glial fibrillary acidic protein -2.87933
FAM156A family with sequence similarity 156, member A -2.87933
CRYGB crystallin, gamma B -2.87933
PGBD4 piggyBac transposable element derived 4 -2.87933
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -2.87933
CLTRN collectrin, amino acid transport regulator -2.87933
SPON2 spondin 2, extracellular matrix protein -2.87933
TECTA tectorin alpha -2.87933
WAS Wiskott-Aldrich syndrome -2.87933
IRX4 iroquois homeobox 4 -2.87933
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.87933
NXPH3 neurexophilin 3 -2.87933
TBC1D25 TBC1 domain family, member 25 -2.87933
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 -2.87933
COLEC10 collectin sub-family member 10 (C-type lectin) -2.87933
NEURL2 neuralized E3 ubiquitin protein ligase 2 -2.87933
MLANA melan-A -2.87933
TUBA4B tubulin, alpha 4b -2.87933
PTN pleiotrophin -2.87933
SBSN suprabasin -2.87933
PRR4 proline rich 4 (lacrimal) -2.87933
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -2.87933
GHRHR growth hormone releasing hormone receptor -2.87933
BRSK2 BR serine/threonine kinase 2 -2.87933
HAPLN2 hyaluronan and proteoglycan link protein 2 -2.87933
CD79B CD79b molecule, immunoglobulin-associated beta -2.87933
KLHL31 kelch-like family member 31 -2.87933
ACOT6 acyl-CoA thioesterase 6 -2.87933
ATP13A4 ATPase type 13A4 -2.87933
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator -2.87933
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 -2.87933
C17ORF107 chromosome 17 open reading frame 107 -2.87933
EXTL1 exostosin-like glycosyltransferase 1 -2.87933
SPEF1 sperm flagellar 1 -2.87933
FBXO48 F-box protein 48 -2.87933
KISS1 KiSS-1 metastasis-suppressor -2.87933
TBXA2R thromboxane A2 receptor -2.87933
AQP4 aquaporin 4 -2.87933
CBX8 chromobox homolog 8 -2.87933
CDH10 cadherin 10, type 2 (T2-cadherin) -2.87933
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -2.87933
RBM20 RNA binding motif protein 20 -2.87933
GTF2A1L general transcription factor IIA, 1-like -2.87933
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.87933
SYT3 synaptotagmin III -2.87933
LRRIQ3 leucine-rich repeats and IQ motif containing 3 -2.87933
KLHL10 kelch-like family member 10 -2.87933
LDLRAD2 low density lipoprotein receptor class A domain containing 2 -2.87933
SCUBE1 signal peptide, CUB domain, EGF-like 1 -2.87933
CERCAM cerebral endothelial cell adhesion molecule -2.86239
DNAL4 dynein, axonemal, light chain 4 -2.85841
FAM8A1 family with sequence similarity 8, member A1 -2.85841
KLHDC4 kelch domain containing 4 -2.85841
CREB5 cAMP responsive element binding protein 5 -2.83772
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.83772
TTC33 tetratricopeptide repeat domain 33 -2.82035
ZDHHC16 zinc finger, DHHC-type containing 16 -2.79997
C18ORF32 chromosome 18 open reading frame 32 -2.79814
TBC1D14 TBC1 domain family, member 14 -2.79595
MRPS31 mitochondrial ribosomal protein S31 -2.78958
IFT52 intraflagellar transport 52 -2.7697
RERG RAS-like, estrogen-regulated, growth inhibitor -2.73036
EXD3 exonuclease 3'-5' domain containing 3 -2.70643
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -2.70643
PCDHA4 protocadherin alpha 4 -2.68534
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.68534
NRXN3 neurexin 3 -2.65929
TBC1D7-LOC100130357 TBC1D7-LOC100130357 readthrough -2.65929
ZSWIM7 zinc finger, SWIM-type containing 7 -2.65929
DGKZ diacylglycerol kinase, zeta -2.65929
SYVN1 synovial apoptosis inhibitor 1, synoviolin -2.51844
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 -2.51722
HELZ2 helicase with zinc finger 2, transcriptional coactivator -2.49442
FBXL15 F-box and leucine-rich repeat protein 15 -2.47355
SRSF6 serine/arginine-rich splicing factor 6 -2.46211
SH2D5 SH2 domain containing 5 -2.27226
EMILIN3 elastin microfibril interfacer 3 -2.24672
SMN2 survival of motor neuron 2, centromeric -2.22444
CHEK2 checkpoint kinase 2 -2.22444
YLPM1 YLP motif containing 1 -2.22357
ZNF570 zinc finger protein 570 -2.20092
NSD2 nuclear receptor binding SET domain protein 2 -2.19642
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.19394
PAH phenylalanine hydroxylase -2.15567
BCL2L11 BCL2-like 11 (apoptosis facilitator) -2.15567
FAM162B family with sequence similarity 162, member B -2.15567
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -2.15516
LHCGR luteinizing hormone/choriogonadotropin receptor -2.15516
GPATCH2L G patch domain containing 2-like -2.13169
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -2.13169
PBX4 pre-B-cell leukemia homeobox 4 -2.1277
MX2 MX dynamin-like GTPase 2 -2.12386
TSPO translocator protein (18kDa) -2.12386
STK40 serine/threonine kinase 40 -2.115
FAM32A family with sequence similarity 32, member A -2.11357
PRPF31 pre-mRNA processing factor 31 -2.08078
PMF1 polyamine-modulated factor 1 -2.08078
TGS1 trimethylguanosine synthase 1 -2.07764
MTBP MDM2 binding protein -2.07596
BICRA BRD4 interacting chromatin remodeling complex associated protein -2.06485
ARMCX5 armadillo repeat containing, X-linked 5 -2.06307
OBI1 ORC ubiquitin ligase 1 -2.05113
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -2.04039
MYOCD myocardin -2.04039
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -2.02226
DEXI Dexi homolog (mouse) -2.02226
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 -2.01927
PEX11B peroxisomal biogenesis factor 11 beta -2.01927
TRIB2 tribbles pseudokinase 2 -2.00814
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 -2.00814
TCF7 transcription factor 7 (T-cell specific, HMG-box) -2.00597
NOP53 NOP53 ribosome biogenesis factor -2.00446