| Dataset | DEPOD Substrates of Phosphatases |
| Category | physical interactions |
| Type | phosphatase |
| Description | protein tyrosine phosphatase, non-receptor type 3|The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] (NCBI Entrez Gene Database, 5774) |
| External Link | http://www.koehn.embl.de/depod/showp.php?gene=PTPN3 |
| Similar Terms | |
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4 substrates of the phosphatase PTPN3 from the curated DEPOD Substrates of Phosphatases dataset.
