PTPN7 Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description protein tyrosine phosphatase, non-receptor type 7|The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5778)
External Link http://www.koehn.embl.de/depod/showp.php?gene=PTPN7
Similar Terms
Downloads & Tools

Genes

3 substrates of the phosphatase PTPN7 from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3