PTPRA Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description protein tyrosine phosphatase, receptor type, A|The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5786)
External Link http://www.ncbi.nlm.nih.gov/gene/5786
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Genes

96 interacting proteins for PTPRA from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BECN1 beclin 1, autophagy related
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTK Bruton agammaglobulinemia tyrosine kinase
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD2AP CD2-associated protein
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNOT1 CCR4-NOT transcription complex, subunit 1
CPNE7 copine VII
CTTN cortactin
DARS aspartyl-tRNA synthetase
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNM2 dynamin 2
DNM3 dynamin 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDARADD EDAR-associated death domain
EGFR epidermal growth factor receptor
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3G eukaryotic translation initiation factor 3, subunit G
ERRFI1 ERBB receptor feedback inhibitor 1
FAM175B family with sequence similarity 175, member B
FUS FUS RNA binding protein
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GABARAPL2 GABA(A) receptor-associated protein-like 2
GRB2 growth factor receptor-bound protein 2
GYG1 glycogenin 1
GYS1 glycogen synthase 1 (muscle)
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPG2 heparan sulfate proteoglycan 2
INS insulin
INSR insulin receptor
IQGAP2 IQ motif containing GTPase activating protein 2
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KIAA0226 KIAA0226
KIAA0226L KIAA0226-like
KIF5B kinesin family member 5B
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT33A keratin 33A, type I
KRT36 keratin 36, type I
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LRRK1 leucine-rich repeat kinase 1
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
NCKIPSD NCK interacting protein with SH3 domain
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NUP160 nucleoporin 160kDa
PASK PAS domain containing serine/threonine kinase
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKCD protein kinase C, delta
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRM protein tyrosine phosphatase, receptor type, M
PTPRS protein tyrosine phosphatase, receptor type, S
PURB purine-rich element binding protein B
RGPD4 RANBP2-like and GRIP domain containing 4
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPS27L ribosomal protein S27-like
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SKAP2 src kinase associated phosphoprotein 2
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFG TRK-fused gene
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TOP2B topoisomerase (DNA) II beta 180kDa
TUBAL3 tubulin, alpha-like 3
UBASH3B ubiquitin associated and SH3 domain containing B
UBC ubiquitin C
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UVRAG UV radiation resistance associated
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR6 WD repeat domain 6
ZNF768 zinc finger protein 768