PTTG1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description pituitary tumor-transforming 1|The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 9232)
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Genes

590 genes differentially expressed following the PTTG1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.48686
CCDC85A coiled-coil domain containing 85A 2.48686
FAM110C family with sequence similarity 110, member C 2.48686
GJB7 gap junction protein, beta 7, 25kDa 2.48686
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.48686
RUBCNL rubicon like autophagy enhancer 2.48686
CNBD2 cyclic nucleotide binding domain containing 2 2.48686
CCK cholecystokinin 2.48686
PLCB2 phospholipase C, beta 2 2.48686
HARBI1 harbinger transposase derived 1 2.48686
SAPCD1 suppressor APC domain containing 1 2.48686
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.48686
ENG endoglin 2.48686
CDKL4 cyclin-dependent kinase-like 4 2.48686
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.48686
BEST4 bestrophin 4 2.48686
ARID5B AT rich interactive domain 5B (MRF1-like) 2.48686
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.48686
GFRA3 GDNF family receptor alpha 3 2.48686
INSYN2A inhibitory synaptic factor 2A 2.48686
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.48686
ELAC1 elaC ribonuclease Z 1 2.48686
CHRM2 cholinergic receptor, muscarinic 2 2.48686
ZNF304 zinc finger protein 304 2.48686
SPDYE2 speedy/RINGO cell cycle regulator family member E2 2.48686
ENO4 enolase family member 4 2.48686
CRIPTO3 cripto, EGF-CFC family member 3 2.48686
RALGDS ral guanine nucleotide dissociation stimulator 2.48686
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 2.48686
GUCA1B guanylate cyclase activator 1B (retina) 2.48686
TELO2 telomere maintenance 2 2.48686
CIART circadian associated repressor of transcription 2.48686
MYO1H myosin IH 2.48686
SCTR secretin receptor 2.48686
H4C13 H4 clustered histone 13 2.48686
FLNC filamin C, gamma 2.48686
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 2.48686
SCAND3 SCAN domain containing 3 2.48686
PRPF38B pre-mRNA processing factor 38B 2.44844
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 2.44844
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.44844
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.44844
PARP14 poly (ADP-ribose) polymerase family, member 14 2.43217
ADK adenosine kinase 2.38465
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.38465
KMT2C lysine (K)-specific methyltransferase 2C 2.37647
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.35766
TMEM177 transmembrane protein 177 2.33828
TSGA10 testis specific, 10 2.3167
MAP3K7CL MAP3K7 C-terminal like 2.30054
LDHD lactate dehydrogenase D 2.30054
ELF4 E74-like factor 4 (ets domain transcription factor) 2.30054
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 2.30054
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 2.30054
CD99 CD99 molecule 2.30054
ZC3H11A zinc finger CCCH-type containing 11A 2.30054
CRY2 cryptochrome circadian clock 2 2.30054
FGF20 fibroblast growth factor 20 2.30054
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.30054
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 2.30054
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.30054
ZNF503 zinc finger protein 503 2.30054
GPR183 G protein-coupled receptor 183 2.30054
HHEX hematopoietically expressed homeobox 2.30054
FUCA1 fucosidase, alpha-L- 1, tissue 2.30054
MGARP mitochondria-localized glutamic acid-rich protein 2.30054
SPDYE5 speedy/RINGO cell cycle regulator family member E5 2.30054
USP50 ubiquitin specific peptidase 50 2.30054
MEP1B meprin A, beta 2.30054
AKAP3 A kinase (PRKA) anchor protein 3 2.30054
ZNF517 zinc finger protein 517 2.30054
ZNF556 zinc finger protein 556 2.30054
CD69 CD69 molecule 2.30054
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 2.30054
SLC26A3 solute carrier family 26 (anion exchanger), member 3 2.30054
ANKRD34B ankyrin repeat domain 34B 2.30054
PITPNM3 PITPNM family member 3 2.30054
RSPO2 R-spondin 2 2.30054
C6ORF52 chromosome 6 open reading frame 52 2.30054
GJB3 gap junction protein, beta 3, 31kDa 2.30054
HES4 hes family bHLH transcription factor 4 2.30054
TMEM100 transmembrane protein 100 2.30054
RUNDC3A RUN domain containing 3A 2.30054
DUSP19 dual specificity phosphatase 19 2.30054
ADTRP androgen-dependent TFPI-regulating protein 2.30054
OSGIN1 oxidative stress induced growth inhibitor 1 2.30054
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.30054
FAM86B1 family with sequence similarity 86, member B1 2.30054
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.30054
SERF1A small EDRK-rich factor 1A (telomeric) 2.30054
ARSA arylsulfatase A 2.30054
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.30054
RXFP1 relaxin/insulin-like family peptide receptor 1 2.30054
CTRC chymotrypsin C (caldecrin) 2.30054
CTRL chymotrypsin-like 2.30054
HYKK hydroxylysine kinase 2.30054
PI15 peptidase inhibitor 15 2.30054
ACTG2 actin, gamma 2, smooth muscle, enteric 2.30054
FBXO6 F-box protein 6 2.30054
DDIT4L DNA-damage-inducible transcript 4-like 2.30054
PEAR1 platelet endothelial aggregation receptor 1 2.30054
CATSPERT catsper channel auxiliary subunit tau 2.30054
ACP3 acid phosphatase 3 2.30054
COQ8A coenzyme Q8A 2.30054
ESS2 ess-2 splicing factor homolog 2.30054
CES4A carboxylesterase 4A 2.30054
EFNB1 ephrin-B1 2.30054
CAPN9 calpain 9 2.30054
CC2D1B coiled-coil and C2 domain containing 1B 2.30054
ACTA2 actin, alpha 2, smooth muscle, aorta 2.30054
SCN4B sodium channel, voltage gated, type IV beta subunit 2.30054
DUSP2 dual specificity phosphatase 2 2.30054
FMO1 flavin containing monooxygenase 1 2.30054
TMPRSS5 transmembrane protease, serine 5 2.30054
KLB klotho beta 2.30054
TRIM34 tripartite motif containing 34 2.30054
SAXO6 stabilizer of axonemal microtubules 6 2.30054
NBPF14 neuroblastoma breakpoint family, member 14 2.30054
TEDC1 tubulin epsilon and delta complex 1 2.30054
SMIM36 small integral membrane protein 36 2.30054
H2BC9 H2B clustered histone 9 2.30054
CIMAP2 ciliary microtubule associated protein 2 2.30054
SMIM47 small integral membrane protein 47 2.30054
SYT15B synaptotagmin 15B 2.30054
PNMA8C PNMA family member 8C 2.30054
SHLD3 shieldin complex subunit 3 2.30054
C20ORF204 chromosome 20 open reading frame 204 2.30054
ACP7 acid phosphatase 7, tartrate resistant (putative) 2.30054
SPDYE21 speedy/RINGO cell cycle regulator family member E21 2.30054
CFAP73 cilia and flagella associated protein 73 2.30054
ITPRID1 ITPR interacting domain containing 1 2.30054
ERFE erythroferrone 2.30054
ECRG4 ECRG4 augurin precursor 2.30054
PLPP7 phospholipid phosphatase 7 (inactive) 2.30054
PIERCE2 piercer of microtubule wall 2 2.30054
BLTP3B bridge-like lipid transfer protein family member 3B 2.30054
EOLA1 endothelium and lymphocyte associated ASCH domain 1 2.30054
ZNF600 zinc finger protein 600 2.30054
THBS3 thrombospondin 3 2.30054
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.30054
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.30054
TOR3A torsin family 3, member A 2.30054
MRPL2 mitochondrial ribosomal protein L2 2.30054
COL6A3 collagen, type VI, alpha 3 2.30054
GOLGA6L4 golgin A6 family-like 4 2.30054
GOLGA6L9 golgin A6 family-like 9 2.30054
RAB11FIP4 RAB11 family interacting protein 4 (class II) 2.30054
RHOBTB2 Rho-related BTB domain containing 2 2.30054
TMEM179 transmembrane protein 179 2.30054
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.30054
CCDC81 coiled-coil domain containing 81 2.30054
THUMPD2 THUMP domain containing 2 2.30054
HYI hydroxypyruvate isomerase (putative) 2.30054
SCRG1 stimulator of chondrogenesis 1 2.30054
ACTL10 actin-like 10 2.30054
IZUMO1 izumo sperm-egg fusion 1 2.30054
HAPLN1 hyaluronan and proteoglycan link protein 1 2.30054
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.30054
TLR2 toll-like receptor 2 2.30054
PRDM6 PR domain containing 6 2.30054
CLVS1 clavesin 1 2.30054
ZAR1L zygote arrest 1-like 2.30054
MYOCD myocardin 2.30054
SAMD10 sterile alpha motif domain containing 10 2.30054
C9 complement component 9 2.30054
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.30054
NPIPB11 nuclear pore complex interacting protein family, member B11 2.30054
ALKBH6 alkB, alkylation repair homolog 6 (E. coli) 2.30054
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.30054
GJD3 gap junction protein, delta 3, 31.9kDa 2.30054
PRR5 proline rich 5 (renal) 2.30054
RASAL1 RAS protein activator like 1 (GAP1 like) 2.30054
C6ORF118 chromosome 6 open reading frame 118 2.30054
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 2.30054
GZMM granzyme M (lymphocyte met-ase 1) 2.30054
ZNF597 zinc finger protein 597 2.30054
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.30054
DGAT2 diacylglycerol O-acyltransferase 2 2.30054
EFCAB8 EF-hand calcium binding domain 8 2.30054
ZFPL1 zinc finger protein-like 1 2.30054
ADORA1 adenosine A1 receptor 2.30054
PABPC4L poly(A) binding protein, cytoplasmic 4-like 2.30054
CCDC74B coiled-coil domain containing 74B 2.30054
LCN2 lipocalin 2 2.30054
ADNP2 ADNP homeobox 2 2.30054
KLF5 Kruppel-like factor 5 (intestinal) 2.30054
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.30054
ZNF628 zinc finger protein 628 2.30054
OAZ2 ornithine decarboxylase antizyme 2 2.30054
CALHM3 calcium homeostasis modulator 3 2.30054
PLET1 placenta expressed transcript 1 2.30054
THOP1 thimet oligopeptidase 1 2.30054
SHISA8 shisa family member 8 2.30054
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.30054
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.30054
ERICH6 glutamate-rich 6 2.30054
WFDC10B WAP four-disulfide core domain 10B 2.30054
CLPSL2 colipase-like 2 2.30054
POTEJ POTE ankyrin domain family, member J 2.30054
PELO pelota homolog (Drosophila) 2.30054
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 2.30054
LIMS3 LIM and senescent cell antigen-like domains 3 2.30054
TMEM154 transmembrane protein 154 2.30054
PRSS53 protease, serine, 53 2.30054
ZNF471 zinc finger protein 471 2.30054
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 2.30054
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.30054
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.30054
APOD apolipoprotein D 2.30054
SPTBN4 spectrin, beta, non-erythrocytic 4 2.30054
CCL25 chemokine (C-C motif) ligand 25 2.30054
CCL28 chemokine (C-C motif) ligand 28 2.30054
MROH8 maestro heat-like repeat family member 8 2.30054
ABHD12B abhydrolase domain containing 12B 2.30054
IL15 interleukin 15 2.30054
LHX8 LIM homeobox 8 2.30054
CCNI2 cyclin I family, member 2 2.30054
PFN4 profilin family, member 4 2.30054
RIBC1 RIB43A domain with coiled-coils 1 2.30054
LDLRAD2 low density lipoprotein receptor class A domain containing 2 2.30054
CAPSL calcyphosine-like 2.30054
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 2.30054
FAIM2 Fas apoptotic inhibitory molecule 2 2.30054
HLA-G major histocompatibility complex, class I, G 2.30054
ABI1 abl-interactor 1 2.30054
GPRC6A G protein-coupled receptor, class C, group 6, member A 2.30054
TMC5 transmembrane channel-like 5 2.30054
BOC BOC cell adhesion associated, oncogene regulated 2.30054
SYT3 synaptotagmin III 2.30054
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.30054
NPM2 nucleophosmin/nucleoplasmin 2 2.30054
DAW1 dynein assembly factor with WDR repeat domains 1 2.30054
FUT2 fucosyltransferase 2 (secretor status included) 2.30054
CHI3L2 chitinase 3-like 2 2.30054
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 2.30054
PCDHA11 protocadherin alpha 11 2.30054
IGF1 insulin-like growth factor 1 (somatomedin C) 2.30054
UTS2B urotensin 2B 2.30054
MAP6 microtubule-associated protein 6 2.30054
HLA-DOA major histocompatibility complex, class II, DO alpha 2.30054
LRP1 low density lipoprotein receptor-related protein 1 2.30054
LRP2 low density lipoprotein receptor-related protein 2 2.30054
PRR35 proline rich 35 2.30054
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 2.30054
LSMEM1 leucine-rich single-pass membrane protein 1 2.30054
SMIM10 small integral membrane protein 10 2.30054
SCUBE3 signal peptide, CUB domain, EGF-like 3 2.30054
TP63 tumor protein p63 2.30054
DLX2 distal-less homeobox 2 2.30054
TMEM200B transmembrane protein 200B 2.30054
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.30054
SNAI3 snail family zinc finger 3 2.30054
MICB MHC class I polypeptide-related sequence B 2.30054
TWIST1 twist family bHLH transcription factor 1 2.30054
ATOH8 atonal homolog 8 (Drosophila) 2.30054
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 2.30054
HIGD1B HIG1 hypoxia inducible domain family, member 1B 2.30054
HYDIN HYDIN, axonemal central pair apparatus protein 2.30054
FXYD3 FXYD domain containing ion transport regulator 3 2.30054
AOAH acyloxyacyl hydrolase (neutrophil) 2.30054
DEF6 differentially expressed in FDCP 6 homolog (mouse) 2.30054
PROM2 prominin 2 2.30054
RDH10 retinol dehydrogenase 10 (all-trans) 2.30054
GPRASP2 G protein-coupled receptor associated sorting protein 2 2.30054
SSPN sarcospan 2.30054
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.30054
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.30054
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.30054
KISS1R KISS1 receptor 2.30054
BEGAIN brain-enriched guanylate kinase-associated 2.30054
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.30054
DCHS2 dachsous cadherin-related 2 2.30054
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 2.30054
NPB neuropeptide B 2.30054
CLCN2 chloride channel, voltage-sensitive 2 2.30054
MYO16 myosin XVI 2.30054
CNTN2 contactin 2 (axonal) 2.30054
FGF8 fibroblast growth factor 8 (androgen-induced) 2.30054
SAXO2 stabilizer of axonemal microtubules 2 2.30054
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.30054
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 2.30054
TPRX1 tetra-peptide repeat homeobox 1 2.30054
HYPK huntingtin interacting protein K 2.30054
SLC25A27 solute carrier family 25, member 27 2.30054
IL10RB interleukin 10 receptor, beta 2.30054
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.30054
ZPLD1 zona pellucida-like domain containing 1 2.30054
ZNF165 zinc finger protein 165 2.30054
ANPEP alanyl (membrane) aminopeptidase 2.30054
DPPA2 developmental pluripotency associated 2 2.30054
CDAN1 codanin 1 2.30054
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.30054
SYCE3 synaptonemal complex central element protein 3 2.30054
PLA2G10 phospholipase A2, group X 2.30054
NLRP1 NLR family, pyrin domain containing 1 2.30054
TIGD3 tigger transposable element derived 3 2.30054
SELENBP1 selenium binding protein 1 2.30054
CD101 CD101 molecule 2.30054
SPDYE11 speedy/RINGO cell cycle regulator family member E11 2.30054
SYTL4 synaptotagmin-like 4 2.30054
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.30054
ELK1 ELK1, member of ETS oncogene family 2.26408
LRRN1 leucine rich repeat neuronal 1 2.2573
WBP1 WW domain binding protein 1 2.25648
RNF43 ring finger protein 43 2.25648
F2R coagulation factor II (thrombin) receptor 2.25648
SP2 Sp2 transcription factor 2.25648
EEF2 eukaryotic translation elongation factor 2 2.25648
SPINK5 serine peptidase inhibitor, Kazal type 5 2.25648
MPPED2 metallophosphoesterase domain containing 2 2.25648
TROAP trophinin associated protein 2.25648
ACSL1 acyl-CoA synthetase long-chain family member 1 2.21681
CA10 carbonic anhydrase X 2.21681
PGAP3 post-GPI attachment to proteins 3 2.21681
C1QTNF3 C1q and tumor necrosis factor related protein 3 2.21681
LRRC8E leucine rich repeat containing 8 family, member E 2.21681
BTN2A1 butyrophilin, subfamily 2, member A1 2.21681
RIPK4 receptor-interacting serine-threonine kinase 4 2.21681
SGMS2 sphingomyelin synthase 2 2.21681
PRR16 proline rich 16 2.21681
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.21681
ACRV1 acrosomal vesicle protein 1 2.21681
LY75 lymphocyte antigen 75 2.21681
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 2.21681
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 2.21681
KHNYN KH and NYN domain containing 2.21681
PGAM2 phosphoglycerate mutase 2 (muscle) 2.21681
TCF25 transcription factor 25 (basic helix-loop-helix) 2.19362
PRRC2A proline-rich coiled-coil 2A 2.18086
RBM47 RNA binding motif protein 47 2.17382
NANOG Nanog homeobox 2.15955
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2.14954
PHF21B PHD finger protein 21B 2.14815
WBP2 WW domain binding protein 2 2.13575
METAP1D methionyl aminopeptidase type 1D (mitochondrial) 2.13575
SAYSD1 SAYSVFN motif domain containing 1 2.13575
CCDC160 coiled-coil domain containing 160 2.13575
ANKRD24 ankyrin repeat domain 24 2.13575
ZNF613 zinc finger protein 613 2.13575
GPATCH1 G patch domain containing 1 2.13575
CHPT1 choline phosphotransferase 1 2.13433
METTL5 methyltransferase like 5 2.11997
MRPL47 mitochondrial ribosomal protein L47 2.1172
TENT5B terminal nucleotidyltransferase 5B 2.10654
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.10476
IFI27L2 interferon, alpha-inducible protein 27-like 2 2.10448
RAB21 RAB21, member RAS oncogene family 2.09575
SNX17 sorting nexin 17 2.09344
CSMD1 CUB and Sushi multiple domains 1 2.09317
ZNHIT1 zinc finger, HIT-type containing 1 2.08031
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.07837
MRPS10 mitochondrial ribosomal protein S10 2.0727
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) 2.05876
PFDN2 prefoldin subunit 2 2.05549
MPC2 mitochondrial pyruvate carrier 2 2.05317
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 2.04646
RHOXF1 Rhox homeobox family, member 1 2.0452
RAE1 ribonucleic acid export 1 2.03893
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 2.03411
RPAP2 RNA polymerase II associated protein 2 2.00508
CTIF CBP80/20-dependent translation initiation factor 2.0001

decreased expression

Symbol Name Standardized Value
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -2.55738
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 -2.48686
NEFM neurofilament, medium polypeptide -2.48686
USP19 ubiquitin specific peptidase 19 -2.48686
DCP1B decapping mRNA 1B -2.48686
ISG15 ISG15 ubiquitin-like modifier -2.48686
ZFHX2 zinc finger homeobox 2 -2.48686
MARF1 meiosis regulator and mRNA stability factor 1 -2.48686
PSMC3IP PSMC3 interacting protein -2.48686
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like -2.48686
HOMER3 homer scaffolding protein 3 -2.48686
PRSS48 protease, serine, 48 -2.48686
THBS4 thrombospondin 4 -2.48686
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -2.48686
OGFR opioid growth factor receptor -2.48686
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D -2.44844
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -2.44844
TMEM234 transmembrane protein 234 -2.44844
RIOX2 ribosomal oxygenase 2 -2.44844
CNIH2 cornichon family AMPA receptor auxiliary protein 2 -2.44844
HPCAL1 hippocalcin-like 1 -2.44844
PRKCE protein kinase C, epsilon -2.44844
FBXW9 F-box and WD repeat domain containing 9 -2.44844
USP51 ubiquitin specific peptidase 51 -2.44844
RIMKLB ribosomal modification protein rimK-like family member B -2.44844
VGLL3 vestigial-like family member 3 -2.44844
C1ORF198 chromosome 1 open reading frame 198 -2.44844
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 -2.44844
C2ORF42 chromosome 2 open reading frame 42 -2.44844
M1AP meiosis 1 associated protein -2.44844
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -2.44422
PLPPR5 phospholipid phosphatase related 5 -2.43217
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -2.43217
TLCD4 TLC domain containing 4 -2.43217
NPW neuropeptide W -2.43217
BCL2L11 BCL2-like 11 (apoptosis facilitator) -2.43217
DMD dystrophin -2.43217
TAPBP TAP binding protein (tapasin) -2.43217
CAVIN3 caveolae associated protein 3 -2.43217
GRK3 G protein-coupled receptor kinase 3 -2.37647
TTI1 TELO2 interacting protein 1 -2.34832
DMC1 DNA meiotic recombinase 1 -2.30054
ICA1L islet cell autoantigen 1,69kDa-like -2.30054
POU2F2 POU class 2 homeobox 2 -2.30054
TIAM1 T-cell lymphoma invasion and metastasis 1 -2.30054
KIAA1671 KIAA1671 -2.30054
SHLD1 shieldin complex subunit 1 -2.30054
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -2.30054
USP49 ubiquitin specific peptidase 49 -2.30054
NVL nuclear VCP-like -2.30054
TANGO2 transport and golgi organization 2 homolog (Drosophila) -2.30054
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -2.30054
GPR158 G protein-coupled receptor 158 -2.30054
SLIT2 slit homolog 2 (Drosophila) -2.30054
TLK2 tousled-like kinase 2 -2.30054
CMTR2 cap methyltransferase 2 -2.30054
HERPUD2 HERPUD family member 2 -2.30054
GPR27 G protein-coupled receptor 27 -2.30054
ASB13 ankyrin repeat and SOCS box containing 13 -2.30054
IFT20 intraflagellar transport 20 -2.30054
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -2.30054
MRAP2 melanocortin 2 receptor accessory protein 2 -2.30054
AXIN2 axin 2 -2.30054
GXYLT2 glucoside xylosyltransferase 2 -2.30054
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -2.30054
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.30054
TPRA1 transmembrane protein, adipocyte asscociated 1 -2.30054
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -2.30054
YIPF3 Yip1 domain family, member 3 -2.30054
STOM stomatin -2.30054
PPA2 pyrophosphatase (inorganic) 2 -2.30054
SLC38A12 solute carrier family 38 member 12 -2.30054
FBXL5 F-box and leucine-rich repeat protein 5 -2.30054
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -2.30054
BIVM basic, immunoglobulin-like variable motif containing -2.30054
GSTZ1 glutathione S-transferase zeta 1 -2.30054
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.30054
FBXO10 F-box protein 10 -2.30054
SLAIN1 SLAIN motif family, member 1 -2.30054
FZD2 frizzled class receptor 2 -2.30054
RIPK2 receptor-interacting serine-threonine kinase 2 -2.30054
KLF8 Kruppel-like factor 8 -2.30054
FHOD3 formin homology 2 domain containing 3 -2.30054
ARL10 ADP-ribosylation factor-like 10 -2.30054
FSAF1 40S small subunit processome assembly factor 1 -2.30054
KRI1 KRI1 homolog (S. cerevisiae) -2.28345
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -2.26496
SORT1 sortilin 1 -2.2573
RELL2 RELT-like 2 -2.25648
ZBTB17 zinc finger and BTB domain containing 17 -2.25648
CPA6 carboxypeptidase A6 -2.25648
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.25648
MED18 mediator complex subunit 18 -2.25648
PRMT2IP PRMT2 interacting protein -2.25648
CDK2 cyclin-dependent kinase 2 -2.25648
BRPF1 bromodomain and PHD finger containing, 1 -2.25648
IL20RB interleukin 20 receptor beta -2.25648
CCDC12 coiled-coil domain containing 12 -2.25648
GPR156 G protein-coupled receptor 156 -2.25648
CFAP210 cilia and flagella associated protein 210 -2.25648
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.25648
ENHO energy homeostasis associated -2.25648
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 -2.25648
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -2.25648
SPICP3 Spi-C transcription factor pseudogene 3 -2.25648
FERMT3 fermitin family member 3 -2.25648
CHD9NB CHD9 neighbor -2.25648
THBS1 thrombospondin 1 -2.25648
RCSD1 RCSD domain containing 1 -2.25648
GALNS galactosamine (N-acetyl)-6-sulfatase -2.25648
PALS1 protein associated with LIN7 1, MAGUK p55 family member -2.25648
H2AC13 H2A clustered histone 13 -2.25648
UBXN6 UBX domain protein 6 -2.25648
EVA1B eva-1 homolog B (C. elegans) -2.25648
METTL18 methyltransferase like 18 -2.25648
FRZB frizzled-related protein -2.25648
CNTNAP3B contactin associated protein-like 3B -2.25648
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.25648
C8ORF58 chromosome 8 open reading frame 58 -2.25648
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 -2.25648
TXK TXK tyrosine kinase -2.25648
ZNF226 zinc finger protein 226 -2.25648
PPP1R37 protein phosphatase 1, regulatory subunit 37 -2.25648
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.25648
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.25648
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -2.25648
SZT2 seizure threshold 2 homolog (mouse) -2.25648
SMIM1 small integral membrane protein 1 (Vel blood group) -2.25648
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -2.25648
CARD9 caspase recruitment domain family, member 9 -2.25648
SLITRK4 SLIT and NTRK-like family, member 4 -2.25648
ADORA2A adenosine A2a receptor -2.25648
MELTF melanotransferrin -2.25648
GLYATL1 glycine-N-acyltransferase-like 1 -2.25648
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit -2.25648
LZTR1 leucine-zipper-like transcription regulator 1 -2.25648
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 -2.25648
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -2.25648
GLI1 GLI family zinc finger 1 -2.25648
ENGASE endo-beta-N-acetylglucosaminidase -2.25648
CRYGS crystallin, gamma S -2.25648
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -2.25648
SPEG SPEG complex locus -2.25648
DNAL4 dynein, axonemal, light chain 4 -2.25648
ZNF57 zinc finger protein 57 -2.25648
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 -2.25648
TOE1 target of EGR1, member 1 (nuclear) -2.25648
BCAN brevican -2.25648
PLPBP pyridoxal phosphate binding protein -2.25648
GPA33 glycoprotein A33 (transmembrane) -2.25648
ANKRD45 ankyrin repeat domain 45 -2.25648
TRIM38 tripartite motif containing 38 -2.25648
AAGAB alpha- and gamma-adaptin binding protein -2.25176
NECTIN1 nectin cell adhesion molecule 1 -2.24392
CCNT2 cyclin T2 -2.21681
PARD6B par-6 family cell polarity regulator beta -2.206
NLGN3 neuroligin 3 -2.19076
ARRB1 arrestin, beta 1 -2.19076
FAM20C family with sequence similarity 20, member C -2.19076
MLH1 mutL homolog 1 -2.17382
ZNF704 zinc finger protein 704 -2.17373
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -2.17241
PRPF3 pre-mRNA processing factor 3 -2.17241
MLX MLX, MAX dimerization protein -2.16597
KLHL28 kelch-like family member 28 -2.15856
ZNF711 zinc finger protein 711 -2.14524
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.13941
CPT1C carnitine palmitoyltransferase 1C -2.13941
ACIN1 apoptotic chromatin condensation inducer 1 -2.13941
TAOK3 TAO kinase 3 -2.12849
MAP2K6 mitogen-activated protein kinase kinase 6 -2.11947
ZNF347 zinc finger protein 347 -2.11718
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -2.11098
PPP1R21 protein phosphatase 1, regulatory subunit 21 -2.09344
PM20D1 peptidase M20 domain containing 1 -2.0727
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 -2.0727
ANGPTL2 angiopoietin-like 2 -2.0727
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -2.0727
LPAR4 lysophosphatidic acid receptor 4 -2.0727
DCC DCC netrin 1 receptor -2.0727
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.0727
H2AC8 H2A clustered histone 8 -2.0727
LRRK1 leucine-rich repeat kinase 1 -2.0727
SNTA1 syntrophin, alpha 1 -2.0727
CCDC7 coiled-coil domain containing 7 -2.0727
FBXL3 F-box and leucine-rich repeat protein 3 -2.0727
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.0727
F3 coagulation factor III (thromboplastin, tissue factor) -2.0727
ESR2 estrogen receptor 2 (ER beta) -2.0727
ZNF75A zinc finger protein 75a -2.0727
TMEM214 transmembrane protein 214 -2.0727
DTX3L deltex 3 like, E3 ubiquitin ligase -2.0727
CCBE1 collagen and calcium binding EGF domains 1 -2.0727
NANOS1 nanos homolog 1 (Drosophila) -2.0727
GNPDA2 glucosamine-6-phosphate deaminase 2 -2.0727
SENP8 SUMO/sentrin specific peptidase family member 8 -2.0727
GLI4 GLI family zinc finger 4 -2.0727
NPTX1 neuronal pentraxin I -2.0727
EFNA3 ephrin-A3 -2.0727
STK17B serine/threonine kinase 17b -2.0727
DCHS1 dachsous cadherin-related 1 -2.0727
RALYL RALY RNA binding protein-like -2.0727
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -2.0605
ATP13A1 ATPase type 13A1 -2.05876
AADAT aminoadipate aminotransferase -2.05876
COL1A2 collagen, type I, alpha 2 -2.05876
FHIP2A FHF complex subunit HOOK interacting protein 2A -2.05876
PABIR3 PABIR family member 3 -2.05876
SMIM11 small integral membrane protein 11 -2.05876
HEXIM2 hexamethylene bis-acetamide inducible 2 -2.05876
RAB32 RAB32, member RAS oncogene family -2.05876
ZBTB21 zinc finger and BTB domain containing 21 -2.05876
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -2.05876
STK11IP serine/threonine kinase 11 interacting protein -2.05876
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.05482
LMTK2 lemur tyrosine kinase 2 -2.04792
PCM1 pericentriolar material 1 -2.04646
TASP1 taspase, threonine aspartase, 1 -2.03893
H2BC5 H2B clustered histone 5 -2.03727
ZNG1B Zn regulated GTPase metalloprotein activator 1B -2.03727
FAM193A family with sequence similarity 193, member A -2.03727
STON1 stonin 1 -2.03597
SPDYA speedy/RINGO cell cycle regulator family member A -2.03597
SRPRB signal recognition particle receptor, B subunit -2.03597
IGFBP4 insulin-like growth factor binding protein 4 -2.03597
MFGE8 milk fat globule-EGF factor 8 protein -2.03576
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 -2.03533
PRDX2 peroxiredoxin 2 -2.02511
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -2.0001