PUF60 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description poly-U binding splicing factor 60KDa|This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 22827)
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Genes

480 genes differentially expressed following the PUF60 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
HSPB6 heat shock protein, alpha-crystallin-related, B6 3.20862
LTC4S leukotriene C4 synthase 3.20862
HTRA3 HtrA serine peptidase 3 3.20862
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 3.20862
CFHR4 complement factor H-related 4 3.20862
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 3.20862
CRYGA crystallin, gamma A 3.20862
NSG2 neuronal vesicle trafficking associated 2 3.20862
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 3.20862
PLN phospholamban 3.20862
TMEM221 transmembrane protein 221 3.20862
C9ORF43 chromosome 9 open reading frame 43 3.20862
STAC2 SH3 and cysteine rich domain 2 3.20862
PCDHB10 protocadherin beta 10 3.20862
CLIC5 chloride intracellular channel 5 3.20862
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 3.20862
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 3.20862
ANKRD30A ankyrin repeat domain 30A 3.20862
GDA guanine deaminase 3.20862
PCDHA6 protocadherin alpha 6 3.20862
LRRC3 leucine rich repeat containing 3 3.20862
TRPV2 transient receptor potential cation channel, subfamily V, member 2 3.20862
SYCP3 synaptonemal complex protein 3 3.20862
CCDC177 coiled-coil domain containing 177 3.20862
C17ORF113 chromosome 17 open reading frame 113 3.20862
ASB14 ankyrin repeat and SOCS box containing 14 3.20862
CYTIP cytohesin 1 interacting protein 3.20862
XKRX XK, Kell blood group complex subunit-related, X-linked 3.20379
OR4M2 olfactory receptor, family 4, subfamily M, member 2 3.20379
AHSG alpha-2-HS-glycoprotein 3.20379
CLDN2 claudin 2 3.20379
POPDC2 popeye domain containing 2 3.20379
NLRP1 NLR family, pyrin domain containing 1 3.20379
ASCL3 achaete-scute family bHLH transcription factor 3 3.20379
CFAP54 cilia and flagella associated 54 3.20379
NLRP11 NLR family, pyrin domain containing 11 3.20379
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 3.20379
PGBDF plakoglobin binding and degradation factor 3.20379
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.20379
IL5RA interleukin 5 receptor, alpha 3.20379
UMOD uromodulin 3.20379
C8ORF48 chromosome 8 open reading frame 48 3.20379
PROB1 proline-rich basic protein 1 3.20379
IRF4 interferon regulatory factor 4 3.20379
POU5F2 POU domain class 5, transcription factor 2 3.20379
C10ORF67 chromosome 10 open reading frame 67 3.20379
CXCL16 chemokine (C-X-C motif) ligand 16 3.20379
AGBL4 ATP/GTP binding protein-like 4 3.20379
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 3.20379
CLCNKA chloride channel, voltage-sensitive Ka 3.20379
CIB3 calcium and integrin binding family member 3 3.20379
DISP2 dispatched homolog 2 (Drosophila) 3.20379
S1PR1 sphingosine-1-phosphate receptor 1 3.20379
TMPRSS12 transmembrane (C-terminal) protease, serine 12 3.20379
AXDND1 axonemal dynein light chain domain containing 1 3.20379
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 3.20379
PDYN prodynorphin 3.20379
GREM1 gremlin 1, DAN family BMP antagonist 3.20379
TAS2R13 taste receptor, type 2, member 13 3.20379
NELL1 NEL-like 1 (chicken) 3.20379
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.20379
FOSL2 FOS-like antigen 2 3.20379
CCR6 chemokine (C-C motif) receptor 6 3.20379
RTN4RL1 reticulon 4 receptor-like 1 3.20379
CCL5 chemokine (C-C motif) ligand 5 3.20379
NKX3-1 NK3 homeobox 1 3.20379
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 3.20379
HEPHL1 hephaestin-like 1 3.20379
AKR1C2 aldo-keto reductase family 1, member C2 3.20379
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 3.20379
HRH4 histamine receptor H4 3.20379
SELPLG selectin P ligand 3.20379
ALB albumin 3.20379
UBA7 ubiquitin-like modifier activating enzyme 7 3.20379
EGFLAM EGF-like, fibronectin type III and laminin G domains 3.20379
NOTO notochord homeobox 3.20379
PLIN1 perilipin 1 3.20379
HCST hematopoietic cell signal transducer 3.20379
CHRND cholinergic receptor, nicotinic, delta (muscle) 3.20379
SLC35G5 solute carrier family 35, member G5 3.20379
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 3.20379
RFPL3 ret finger protein-like 3 3.20379
C11ORF86 chromosome 11 open reading frame 86 3.20379
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 3.20379
ATOH1 atonal homolog 1 (Drosophila) 3.20379
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.20379
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.20379
FAM81B family with sequence similarity 81, member B 3.20379
SLC22A10 solute carrier family 22, member 10 3.20379
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 3.20379
DNAH2 dynein, axonemal, heavy chain 2 3.20379
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 3.20379
WEE2 WEE1 homolog 2 (S. pombe) 3.20379
NWD1 NACHT and WD repeat domain containing 1 3.20379
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 3.20379
LOC105378220 macrophage receptor MARCO-like 3.20379
CDRT15 CMT1A duplicated region transcript 15 3.20379
LOX lysyl oxidase 3.20379
CSNK2A3 casein kinase 2, alpha 3 polypeptide 3.20379
OVCH1 ovochymase 1 3.20379
TMC3 transmembrane channel-like 3 3.20379
MRC1 mannose receptor, C type 1 3.20379
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.20379
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 3.20379
AKNAD1 AKNA domain containing 1 3.20379
TEKT1 tektin 1 3.20379
PRDM9 PR domain containing 9 3.20379
CRACDL CRACD like 3.20379
SPATA9 spermatogenesis associated 9 3.20379
MAJIN membrane anchored junction protein 3.20379
MAP6 microtubule-associated protein 6 3.20379
ITGB6 integrin, beta 6 3.20379
ITGB7 integrin, beta 7 3.20379
CRYBA1 crystallin, beta A1 3.20379
TEKT5 tektin 5 3.20379
BCO1 beta-carotene oxygenase 1 3.20379
CFAP65 cilia and flagella associated protein 65 3.20379
CLDN16 claudin 16 3.20379
CLEC4F C-type lectin domain family 4, member F 3.20379
MAMLD1 mastermind-like domain containing 1 3.20379
KY kyphoscoliosis peptidase 3.20379
H3-5 H3.5 histone 3.20379
PCDHGA7 protocadherin gamma subfamily A, 7 3.20379
PCDHGA2 protocadherin gamma subfamily A, 2 3.20379
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase 3.20379
HCLS1 hematopoietic cell-specific Lyn substrate 1 3.20379
MUCL3 mucin like 3 3.20379
CD200R1 CD200 receptor 1 3.20379
TPPP2 tubulin polymerization-promoting protein family member 2 3.20379
PCSK1 proprotein convertase subtilisin/kexin type 1 3.20379
MAP1A microtubule-associated protein 1A 3.20379
PLA2G5 phospholipase A2, group V 3.20379
TTC22 tetratricopeptide repeat domain 22 3.20379
ADRA2A adrenoceptor alpha 2A 3.20379
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 3.20379
OR52N2 olfactory receptor, family 52, subfamily N, member 2 3.20379
NLRP14 NLR family, pyrin domain containing 14 3.20379
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 3.20379
HLA-DMB major histocompatibility complex, class II, DM beta 3.20379
IL26 interleukin 26 3.20379
ESPNL espin-like 3.20379
AGER advanced glycosylation end product-specific receptor 3.20379
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 3.20379
PEAK3 PEAK family member 3 3.20379
HIGD2B HIG1 hypoxia inducible domain family, member 2B 3.20379
PLCD4 phospholipase C, delta 4 3.20379
LYPD5 LY6/PLAUR domain containing 5 3.20379
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.20379
GCGR glucagon receptor 3.20379
H3C13 H3 clustered histone 13 3.20379
PCDHGB4 protocadherin gamma subfamily B, 4 3.20379
TLR1 toll-like receptor 1 3.20379
CALML6 calmodulin-like 6 3.20379
RBM44 RNA binding motif protein 44 3.20379
FAM131C family with sequence similarity 131, member C 3.20379
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 3.20379
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 3.20379
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 3.20379
PMP2 peripheral myelin protein 2 3.20379
KL klotho 3.20379
HP haptoglobin 3.20379
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.20379
LEF1 lymphoid enhancer-binding factor 1 3.20379
TFEC transcription factor EC 3.20379
CHAD chondroadherin 3.20379
RHAG Rh-associated glycoprotein 3.20379
APOL1 apolipoprotein L, 1 3.20379
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 3.20379
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 3.20379
NPAS4 neuronal PAS domain protein 4 3.20379
ZNF534 zinc finger protein 534 3.20379
OR2AP1 olfactory receptor, family 2, subfamily AP, member 1 3.20379
C5AR2 complement component 5a receptor 2 3.20379
LEKR1 leucine, glutamate and lysine rich 1 3.20379
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3.20379
WNT16 wingless-type MMTV integration site family, member 16 3.20379
AQP4 aquaporin 4 3.20379
CXCR2 chemokine (C-X-C motif) receptor 2 3.20379
S100Z S100 calcium binding protein Z 3.20379
HSPA1L heat shock 70kDa protein 1-like 3.20379
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 3.20379
CDHR1 cadherin-related family member 1 3.20379
RTBDN retbindin 3.20379
CXCL13 chemokine (C-X-C motif) ligand 13 3.20379
SCEL sciellin 3.20379
THTPA thiamine triphosphatase 3.20379
LYG2 lysozyme G-like 2 3.20379
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 3.20379
TSNAXIP1 translin-associated factor X interacting protein 1 3.20379
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 3.20379
HSPA6 heat shock 70kDa protein 6 (HSP70B') 3.20379
BDKRB2 bradykinin receptor B2 3.20379
SMKR1 small lysine-rich protein 1 3.20379
ASB9 ankyrin repeat and SOCS box containing 9 3.20379
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 3.20379
LCT lactase 3.20379
CALHM3 calcium homeostasis modulator 3 3.20379
PHETA2 PH domain containing endocytic trafficking adaptor 2 3.17313
ARRB1 arrestin, beta 1 3.14125
PNMA6A paraneoplastic Ma antigen family member 6A 3.07877
APC2 adenomatosis polyposis coli 2 3.07877
CD37 CD37 molecule 3.07877
CCDC183 coiled-coil domain containing 183 3.07877
MME membrane metallo-endopeptidase 2.99644
C10ORF90 chromosome 10 open reading frame 90 2.99644
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.90254
CLIC1 chloride intracellular channel 1 2.88855
SEC61B Sec61 beta subunit 2.84777
POM121L2 POM121 transmembrane nucleoporin-like 2 2.76655
SERGEF secretion regulating guanine nucleotide exchange factor 2.76318
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.75053
SMG6 SMG6 nonsense mediated mRNA decay factor 2.75053
MEST mesoderm specific transcript 2.75053
TMEM64 transmembrane protein 64 2.73577
FBXO45 F-box protein 45 2.73243
MAP2K5-DT MAP2K5 divergent transcript 2.7198
PARP10 poly (ADP-ribose) polymerase family, member 10 2.7198
KASH5 KASH domain containing 5 2.7198
WDR5B WD repeat domain 5B 2.7198
TXNL1 thioredoxin-like 1 2.69669
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 2.61317
ZMAT3 zinc finger, matrin-type 3 2.60472
ANAPC16 anaphase promoting complex subunit 16 2.58694
OR4D1 olfactory receptor, family 4, subfamily D, member 1 2.53066
SLC10A4 solute carrier family 10, member 4 2.53066
ZNF85 zinc finger protein 85 2.49572
HPS1 Hermansky-Pudlak syndrome 1 2.48371
MRPL32 mitochondrial ribosomal protein L32 2.45868
ZNF665 zinc finger protein 665 2.44401
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 2.44053
MANBAL mannosidase, beta A, lysosomal-like 2.39617
HYKK hydroxylysine kinase 2.39142
GPNMB glycoprotein (transmembrane) nmb 2.38267
STX1B syntaxin 1B 2.38184
IER2 immediate early response 2 2.35742
CLPTM1L CLPTM1-like 2.33949
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.32879
AMZ1 archaelysin family metallopeptidase 1 2.32833
TCEA2 transcription elongation factor A (SII), 2 2.32551
DDB1 damage-specific DNA binding protein 1, 127kDa 2.32551
TMSB10 thymosin beta 10 2.30853
TPT1 tumor protein, translationally-controlled 1 2.30402
FASN fatty acid synthase 2.30402
NOXRED1 NADP-dependent oxidoreductase domain containing 1 2.30348
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 2.30348
TFDP1 transcription factor Dp-1 2.29972
SRM spermidine synthase 2.29493
MYO3A myosin IIIA 2.26582
MED11 mediator complex subunit 11 2.26464
EXOSC4 exosome component 4 2.25873
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.24496
VPS35L VPS35 endosomal protein sorting factor like 2.22668
GLMP glycosylated lysosomal membrane protein 2.22288
PRRT1 proline-rich transmembrane protein 1 2.22155
STBD1 starch binding domain 1 2.22155
RHCE Rh blood group, CcEe antigens 2.22155
DRC10 dynein regulatory complex subunit 10 2.22155
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.22155
MTNR1A melatonin receptor 1A 2.22155
LRRIQ1 leucine-rich repeats and IQ motif containing 1 2.22155
MYCBPAP MYCBP associated protein 2.22155
CLSTN2 calsyntenin 2 2.22155
TRAPPC2 trafficking protein particle complex 2 2.21982
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.21039
FNTB farnesyltransferase, CAAX box, beta 2.21039
XKR5 XK, Kell blood group complex subunit-related family, member 5 2.20233
PDIA6 protein disulfide isomerase family A, member 6 2.19948
RPL27A ribosomal protein L27a 2.19498
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 2.17544
STAG2 stromal antigen 2 2.16701
GRIK2 glutamate receptor, ionotropic, kainate 2 2.16537
SLC19A1 solute carrier family 19 (folate transporter), member 1 2.14533
LSAMP limbic system-associated membrane protein 2.13956
MOCOS molybdenum cofactor sulfurase 2.13807
FAM114A2 family with sequence similarity 114, member A2 2.13807
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) 2.13298
EEF1G eukaryotic translation elongation factor 1 gamma 2.12197
MARVELD1 MARVEL domain containing 1 2.11941
AFG1L AFG1 like ATPase 2.11317
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.10078
FHL3 four and a half LIM domains 3 2.10078
UBE2E3 ubiquitin-conjugating enzyme E2E 3 2.09725
IER3IP1 immediate early response 3 interacting protein 1 2.09274
MRPS25 mitochondrial ribosomal protein S25 2.09274
STK38 serine/threonine kinase 38 2.09219
KIRREL1 kirre like nephrin family adhesion molecule 1 2.09219
CEP131 centrosomal protein 131kDa 2.09219
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.09219
SIAE sialic acid acetylesterase 2.09127
PLAAT5 phospholipase A and acyltransferase 5 2.09127
FBXW9 F-box and WD repeat domain containing 9 2.08991
COL1A1 collagen, type I, alpha 1 2.08991
STX3 syntaxin 3 2.08991
ZBBX zinc finger, B-box domain containing 2.08947
TEAD4 TEA domain family member 4 2.07799
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30 2.07799
VAT1 vesicle amine transport 1 2.07082
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.06679
TET1 tet methylcytosine dioxygenase 1 2.05035
THAP10 THAP domain containing 10 2.04829
IQANK1 IQ motif and ankyrin repeat containing 1 2.04597
RPL22 ribosomal protein L22 2.03592
RPL19 ribosomal protein L19 2.02986
CDC16 cell division cycle 16 2.02986
SLC66A2 solute carrier family 66 member 2 2.02986
MPRIP myosin phosphatase Rho interacting protein 2.02986
IRAK1 interleukin-1 receptor-associated kinase 1 2.02447
MCMBP minichromosome maintenance complex binding protein 2.02447
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.02447
ZNF2 zinc finger protein 2 2.02253
C1ORF74 chromosome 1 open reading frame 74 2.02253
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 2.02213
LIPA lipase A, lysosomal acid, cholesterol esterase 2.01706
CCNH cyclin H 2.01459
TIGD1 tigger transposable element derived 1 2.0089
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.00803
DAZL deleted in azoospermia-like 2.00803
NGRN neugrin, neurite outgrowth associated 2.00385

decreased expression

Symbol Name Standardized Value
ITPKC inositol-trisphosphate 3-kinase C -3.20862
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing -3.20379
EEF2K eukaryotic elongation factor 2 kinase -3.20379
HNRNPM heterogeneous nuclear ribonucleoprotein M -3.20379
RLN2 relaxin 2 -3.20379
SLC71A1 solute carrier family 71 member 1 -3.20379
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -3.20379
EFCAB5 EF-hand calcium binding domain 5 -3.20379
DNAAF3 dynein, axonemal, assembly factor 3 -3.20379
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -3.20379
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF -3.20379
GMPR2 guanosine monophosphate reductase 2 -3.14123
TMEM229B transmembrane protein 229B -3.07877
PCDHGA1 protocadherin gamma subfamily A, 1 -3.07877
PCDHA7 protocadherin alpha 7 -3.07877
SPDYE16 speedy/RINGO cell cycle regulator family member E16 -3.07877
PEBP4 phosphatidylethanolamine-binding protein 4 -3.07877
MFSD6L major facilitator superfamily domain containing 6-like -3.07877
AKAP14 A kinase (PRKA) anchor protein 14 -3.07877
ZNF182 zinc finger protein 182 -3.07877
DGAT2 diacylglycerol O-acyltransferase 2 -3.07877
COL16A1 collagen, type XVI, alpha 1 -3.07877
FAM133A family with sequence similarity 133, member A -3.07877
ACAN aggrecan -3.07877
DUSP9 dual specificity phosphatase 9 -3.07877
CCDC68 coiled-coil domain containing 68 -3.07877
PCDH9 protocadherin 9 -3.07877
ANKRD37 ankyrin repeat domain 37 -3.07877
RIPOR1 RHO family interacting cell polarization regulator 1 -3.07877
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 -3.07877
MEOX2 mesenchyme homeobox 2 -3.07877
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -3.07877
C2CD4D C2 calcium-dependent domain containing 4D -3.07877
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -3.07877
MSR1 macrophage scavenger receptor 1 -3.07877
ZEB1 zinc finger E-box binding homeobox 1 -3.07877
ANKDD1B ankyrin repeat and death domain containing 1B -3.07877
RAB27B RAB27B, member RAS oncogene family -3.07877
ZNF256 zinc finger protein 256 -3.0316
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -3.0316
DOC2A double C2-like domains, alpha -3.0099
WDR11 WD repeat domain 11 -2.98894
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.96314
DACT1 dishevelled-binding antagonist of beta-catenin 1 -2.91219
PCDH10 protocadherin 10 -2.87815
ANAPC7 anaphase promoting complex subunit 7 -2.85682
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -2.80685
PGPEP1 pyroglutamyl-peptidase I -2.80217
SUSD4 sushi domain containing 4 -2.77269
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.75053
APAF1 apoptotic peptidase activating factor 1 -2.75053
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.72215
REEP6 receptor accessory protein 6 -2.72178
C8ORF82 chromosome 8 open reading frame 82 -2.7198
GRID2 glutamate receptor, ionotropic, delta 2 -2.7176
PYGO1 pygopus family PHD finger 1 -2.6798
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.6798
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.67062
SAXO6 stabilizer of axonemal microtubules 6 -2.65935
CUL3 cullin 3 -2.61276
LNPEP leucyl/cystinyl aminopeptidase -2.61254
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -2.5861
MAPK8 mitogen-activated protein kinase 8 -2.57846
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) -2.5027
DKK3 dickkopf WNT signaling pathway inhibitor 3 -2.49572
SRC SRC proto-oncogene, non-receptor tyrosine kinase -2.47901
MRPL40 mitochondrial ribosomal protein L40 -2.46906
SHLD3 shieldin complex subunit 3 -2.46191
ZNF628 zinc finger protein 628 -2.46191
NPIPB12 nuclear pore complex interacting protein family member B12 -2.46191
SMN1 survival of motor neuron 1, telomeric -2.45868
EML6 echinoderm microtubule associated protein like 6 -2.44855
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.44123
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -2.42441
TBC1D24 TBC1 domain family, member 24 -2.39696
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 -2.39617
MYH11 myosin, heavy chain 11, smooth muscle -2.39617
HRH3 histamine receptor H3 -2.39617
RORA RAR-related orphan receptor A -2.39617
LIPI lipase, member I -2.39617
ELOVL2 ELOVL fatty acid elongase 2 -2.39617
VCL vinculin -2.3935
SETD3 SET domain containing 3 -2.39145
TMEM101 transmembrane protein 101 -2.38184
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -2.37675
DMWD dystrophia myotonica, WD repeat containing -2.35445
TRIM35 tripartite motif containing 35 -2.34276
IQSEC2 IQ motif and Sec7 domain 2 -2.33949
AKAP19 A-kinase anchoring protein 19 -2.33374
SNX18 sorting nexin 18 -2.32879
CELF2 CUGBP, Elav-like family member 2 -2.32835
AIF1L allograft inflammatory factor 1-like -2.32833
ZNF451 zinc finger protein 451 -2.32833
CABIN1 calcineurin binding protein 1 -2.32824
AK6 adenylate kinase 6 -2.32551
PRKCE protein kinase C, epsilon -2.3107
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.30853
KRAS Kirsten rat sarcoma viral oncogene homolog -2.30853
ANO6 anoctamin 6 -2.30853
PLXNB2 plexin B2 -2.30571
CCDC142 coiled-coil domain containing 142 -2.29956
TUSC3 tumor suppressor candidate 3 -2.28367
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.27738
TGIF2 TGFB-induced factor homeobox 2 -2.26999
ILF3 interleukin enhancer binding factor 3, 90kDa -2.26986
OIP5 Opa interacting protein 5 -2.26986
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.26986
GXYLT1 glucoside xylosyltransferase 1 -2.26986
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.26658
TRMO tRNA methyltransferase O -2.26582
STK33 serine/threonine kinase 33 -2.26582
POLRMT polymerase (RNA) mitochondrial (DNA directed) -2.26464
ACSM6 acyl-CoA synthetase medium-chain family member 6 -2.23375
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.22668
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.22288
TMEM130 transmembrane protein 130 -2.22288
ELOVL7 ELOVL fatty acid elongase 7 -2.22288
NUTM1 NUT midline carcinoma, family member 1 -2.22288
ASIC1 acid sensing (proton gated) ion channel 1 -2.22288
PGAM5 phosphoglycerate mutase family member 5 -2.22288
TYRO3 TYRO3 protein tyrosine kinase -2.22288
GRM8 glutamate receptor, metabotropic 8 -2.22155
MIF4GD MIF4G domain containing -2.21562
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -2.21502
ESPN espin -2.21502
PLBD2 phospholipase B domain containing 2 -2.2134
ELOF1 elongation factor 1 homolog (S. cerevisiae) -2.21039
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B -2.20475
CALCOCO1 calcium binding and coiled-coil domain 1 -2.19498
PARP8 poly (ADP-ribose) polymerase family, member 8 -2.19498
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.18139
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.17544
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) -2.17527
OPCML opioid binding protein/cell adhesion molecule-like -2.16408
EIF2D eukaryotic translation initiation factor 2D -2.13893
MFN2 mitofusin 2 -2.12687
MEGF10 multiple EGF-like-domains 10 -2.09791
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -2.09274
TDRP testis development related protein -2.09219
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -2.08991
SYAP1 synapse associated protein 1 -2.08991
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -2.08475
COL4A4 collagen, type IV, alpha 4 -2.0748
USP40 ubiquitin specific peptidase 40 -2.06878
IGSF3 immunoglobulin superfamily, member 3 -2.06826
MRPL58 mitochondrial ribosomal protein L58 -2.06737
MRPS9 mitochondrial ribosomal protein S9 -2.05625
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -2.04554
ATF6 activating transcription factor 6 -2.036
PARP2 poly (ADP-ribose) polymerase 2 -2.03592
STRA6 stimulated by retinoic acid 6 -2.03178
TMED4 transmembrane emp24 protein transport domain containing 4 -2.03127
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.03127
ARCN1 archain 1 -2.03076
MIS18BP1 MIS18 binding protein 1 -2.02986
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -2.01963
RAE1 ribonucleic acid export 1 -2.01963
CAV2 caveolin 2 -2.01963
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.01623
RAB30 RAB30, member RAS oncogene family -2.01623
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 -2.01623
PRMT6 protein arginine methyltransferase 6 -2.01623