PXK Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description PX domain containing serine/threonine kinase|This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 54899)
External Link https://ncbi.nlm.nih.gov/gene/54899
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Genes

499 genes differentially expressed following the PXK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAS GNAS complex locus 0.0225554
LIMCH1 LIM and calponin homology domains 1 0.0184173
FABP4 fatty acid binding protein 4, adipocyte 0.0180144
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0166772
MECOM MDS1 and EVI1 complex locus 0.0160913
KRT7 keratin 7, type II 0.0150138
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0149818
OXA1L oxidase (cytochrome c) assembly 1-like 0.0144071
PODXL podocalyxin-like 0.0140888
TENT5A terminal nucleotidyltransferase 5A 0.0124872
TGM2 transglutaminase 2 0.0123835
PDZD2 PDZ domain containing 2 0.0114482
PCNA proliferating cell nuclear antigen 0.0113883
FBLN5 fibulin 5 0.0113689
MFAP5 microfibrillar associated protein 5 0.0111656
BTBD3 BTB (POZ) domain containing 3 0.0110803
ASPN asporin 0.0110097
VLDLR very low density lipoprotein receptor 0.0109814
GSTA4 glutathione S-transferase alpha 4 0.0107497
SLPI secretory leukocyte peptidase inhibitor 0.0107179
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.0103405
RGS5 regulator of G-protein signaling 5 0.0103296
MCOLN1 mucolipin 1 0.0103291
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0103228
SFTPD surfactant protein D 0.0102755
MGLL monoglyceride lipase 0.0102587
CFH complement factor H 0.010187
CCP110 centriolar coiled coil protein 110kDa 0.00999199
SLIT2 slit homolog 2 (Drosophila) 0.00996966
UBXN7 UBX domain protein 7 0.00990634
TGFBR3 transforming growth factor, beta receptor III 0.00985384
PTCH1 patched 1 0.0096728
LTBP2 latent transforming growth factor beta binding protein 2 0.00960894
INHBA inhibin, beta A 0.00958183
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00957842
PLS3 plastin 3 0.00957817
ADGRF5 adhesion G protein-coupled receptor F5 0.00956417
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00954434
RET ret proto-oncogene 0.00954034
CHRDL1 chordin-like 1 0.00951773
FMO2 flavin containing monooxygenase 2 (non-functional) 0.0093516
TCF4 transcription factor 4 0.00916061
LAMP5 lysosomal-associated membrane protein family, member 5 0.00914408
DCN decorin 0.00905801
ABLIM1 actin binding LIM protein 1 0.00900039
AQP3 aquaporin 3 (Gill blood group) 0.00897478
ITGA6 integrin, alpha 6 0.00885651
FGF9 fibroblast growth factor 9 0.00885158
TM4SF1 transmembrane 4 L six family member 1 0.0087353
CXADR coxsackie virus and adenovirus receptor 0.00870496
PDHX pyruvate dehydrogenase complex, component X 0.00867703
SLC35G2 solute carrier family 35, member G2 0.00859693
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00857715
KRT6A keratin 6A, type II 0.00850054
KANK1 KN motif and ankyrin repeat domains 1 0.00848908
S100A8 S100 calcium binding protein A8 0.00846754
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.00845541
IFI44L interferon-induced protein 44-like 0.00844252
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00840052
SRSF5 serine/arginine-rich splicing factor 5 0.00838682
ZMYND8 zinc finger, MYND-type containing 8 0.00836076
TRIM29 tripartite motif containing 29 0.00835151
GPM6B glycoprotein M6B 0.00832826
RELN reelin 0.00825649
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00824742
HOPX HOP homeobox 0.00823586
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00821556
TRIM44 tripartite motif containing 44 0.00815242
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00814148
CD34 CD34 molecule 0.00813745
S100A9 S100 calcium binding protein A9 0.00810054
DYNLL1 dynein, light chain, LC8-type 1 0.00808907
ADAMTSL3 ADAMTS-like 3 0.00804124
C3 complement component 3 0.00802265
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00799808
ELP1 elongator acetyltransferase complex subunit 1 0.00798975
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0078082
DPP8 dipeptidyl-peptidase 8 0.00780127
ECPAS Ecm29 proteasome adaptor and scaffold 0.00777022
STK10 serine/threonine kinase 10 0.00772112
CD59 CD59 molecule, complement regulatory protein 0.00768967
EHD3 EH-domain containing 3 0.00768874
TMEM45A transmembrane protein 45A 0.00768701
KRT14 keratin 14, type I 0.00768698
EGFL6 EGF-like-domain, multiple 6 0.00765843
ERMP1 endoplasmic reticulum metallopeptidase 1 0.00765523
KAZN kazrin, periplakin interacting protein 0.00761825
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.00760505
KRT17 keratin 17, type I 0.00758134
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00758016
GPI glucose-6-phosphate isomerase 0.0075771
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.0075677
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.00755749
NOP56 NOP56 ribonucleoprotein 0.00754405
SH3BP4 SH3-domain binding protein 4 0.00753896
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00751176
KRT6B keratin 6B, type II 0.00750898
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00747295
IRS2 insulin receptor substrate 2 0.00744236
PCCB propionyl CoA carboxylase, beta polypeptide 0.00742782
MEOX2 mesenchyme homeobox 2 0.00740382
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00739932
GOLGA8H golgin A8 family, member H 0.00737798
FASN fatty acid synthase 0.00735882
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00735343
MMP10 matrix metallopeptidase 10 0.00733278
PLTP phospholipid transfer protein 0.00732826
KRT13 keratin 13, type I 0.00730476
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00729413
SIK1 salt-inducible kinase 1 0.00729033
TMEM204 transmembrane protein 204 0.007281
MIA melanoma inhibitory activity 0.00721317
CELF2 CUGBP, Elav-like family member 2 0.00720084
EMP1 epithelial membrane protein 1 0.00715944
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.0071533
DCHS1 dachsous cadherin-related 1 0.00714886
CLEC3B C-type lectin domain family 3, member B 0.0071335
CD163 CD163 molecule 0.00713324
SECISBP2L SECIS binding protein 2-like 0.00713278
EMCN endomucin 0.00711845
ITM2A integral membrane protein 2A 0.00710439
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00710075
ZNF281 zinc finger protein 281 0.00709383
TUBB2A tubulin, beta 2A class IIa 0.00708472
KIF14 kinesin family member 14 0.00706584
RUNX3 runt-related transcription factor 3 0.00700876
NRN1 neuritin 1 0.00700678
FNDC3B fibronectin type III domain containing 3B 0.00699662
CYB5R2 cytochrome b5 reductase 2 0.00698499
MFAP4 microfibrillar-associated protein 4 0.00697716
LAMB1 laminin, beta 1 0.00688238
TMEM230 transmembrane protein 230 0.00684731
KLC1 kinesin light chain 1 0.00684387
CXCL8 chemokine (C-X-C motif) ligand 8 0.00684276
SETD5 SET domain containing 5 0.00683851
MACF1 microtubule-actin crosslinking factor 1 0.00682311
TFRC transferrin receptor 0.00680547
ANOS1 anosmin 1 0.00679747
CD93 CD93 molecule 0.00677802
MPDZ multiple PDZ domain protein 0.00677014
VCP valosin containing protein 0.00674933
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00673511
S100A2 S100 calcium binding protein A2 0.00669247
KRT5 keratin 5, type II 0.00665009
TJP2 tight junction protein 2 0.00663604
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.00660472
FPGS folylpolyglutamate synthase 0.00658794
COL9A3 collagen, type IX, alpha 3 0.00657426
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00656784
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.00654944
SOX11 SRY (sex determining region Y)-box 11 0.00654002
MYO5C myosin VC 0.00653683
MAST4 microtubule associated serine/threonine kinase family member 4 0.00653421
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.0065147
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.0065045
MAP7 microtubule-associated protein 7 0.00648078
C8ORF4 chromosome 8 open reading frame 4 0.00647652
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00647496
GPC4 glypican 4 0.00647158
PPL periplakin 0.00645817
NFASC neurofascin 0.00645509
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00644533
PLPP2 phospholipid phosphatase 2 0.00643893
DST dystonin 0.00641415
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00639064
CLIC5 chloride intracellular channel 5 0.00638752
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00636976
RPL36AL ribosomal protein L36a-like 0.00635859
XYLT1 xylosyltransferase I 0.0063481
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00633861
ANXA3 annexin A3 0.00633191
PALMD palmdelphin 0.00631686
PDLIM2 PDZ and LIM domain 2 (mystique) 0.00630461
RGCC regulator of cell cycle 0.0062987
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00629408
FZD10 frizzled class receptor 10 0.00629126
LEPR leptin receptor 0.00628493
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00628401
DHCR24 24-dehydrocholesterol reductase 0.00626149
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00625746
HMG20B high mobility group 20B 0.00622432
MARCO macrophage receptor with collagenous structure 0.00620207
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00617966
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00616181
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00615849
FASTKD5 FAST kinase domains 5 0.00615324
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00614645
CLEC2B C-type lectin domain family 2, member B 0.00613133
LYPD3 LY6/PLAUR domain containing 3 0.00610792
ADIPOR2 adiponectin receptor 2 0.00608675
BCAP31 B-cell receptor-associated protein 31 0.00607326
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00606516
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.0060552
MFGE8 milk fat globule-EGF factor 8 protein 0.00604802
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00604547
KIAA0125 KIAA0125 0.00604486
AOC3 amine oxidase, copper containing 3 0.00604367
PUM1 pumilio RNA-binding family member 1 0.00604201
MELK maternal embryonic leucine zipper kinase 0.00603103
THBS2 thrombospondin 2 0.00603077
TNXB tenascin XB 0.00602797
EMP2 epithelial membrane protein 2 0.00598957
GPX3 glutathione peroxidase 3 0.0059865
CCN3 cellular communication network factor 3 0.00598124
LUM lumican 0.0059778
MEIS1 Meis homeobox 1 0.00596732
PGC progastricsin (pepsinogen C) 0.00596539
CXCL14 chemokine (C-X-C motif) ligand 14 0.00596168
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00595101
PLIN1 perilipin 1 0.00594583
CXCL12 chemokine (C-X-C motif) ligand 12 0.00594157
FOXD1 forkhead box D1 0.00593636
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.00593071
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00592535
LONP1 lon peptidase 1, mitochondrial 0.0059238
L1CAM L1 cell adhesion molecule 0.00592275
PHACTR2 phosphatase and actin regulator 2 0.00591001
WISP2 WNT1 inducible signaling pathway protein 2 0.00590592
DDRGK1 DDRGK domain containing 1 0.00590572
SYT11 synaptotagmin XI 0.00589223
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.00589039
MPPED2 metallophosphoesterase domain containing 2 0.00588927
IL33R interleukin 33 receptor 0.005889
FZD2 frizzled class receptor 2 0.0058882
QDPR quinoid dihydropteridine reductase 0.00588043
MSLN mesothelin 0.00587845
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00587049
ETV5 ets variant 5 0.00586868
NXN nucleoredoxin 0.00584146
MPO myeloperoxidase 0.00583929
SFRP4 secreted frizzled-related protein 4 0.00582812
COPS7A COP9 signalosome subunit 7A 0.00581781
TSPAN13 tetraspanin 13 0.00581634
CCN2 cellular communication network factor 2 0.00581268
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00581107
JADE1 jade family PHD finger 1 0.00580842
CRABP2 cellular retinoic acid binding protein 2 0.00579261
TP63 tumor protein p63 0.00577665
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00577062
GLTP glycolipid transfer protein 0.00576985
PMP22 peripheral myelin protein 22 0.00576129
OXTR oxytocin receptor 0.00575413
MTA1 metastasis associated 1 0.00575126
AOX1 aldehyde oxidase 1 0.00573865
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00573257
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.00572388
LPIN1 lipin 1 0.00572174
PRRC2C proline-rich coiled-coil 2C 0.00571878
MYLIP myosin regulatory light chain interacting protein 0.00571064
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00571055

decreased expression

Symbol Name Standardized Value
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.014533
LGALS2 lectin, galactoside-binding, soluble, 2 -0.0133549
MDK midkine (neurite growth-promoting factor 2) -0.0133244
ANPEP alanyl (membrane) aminopeptidase -0.012505
CDC20 cell division cycle 20 -0.0122483
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0121415
IGFBP5 insulin-like growth factor binding protein 5 -0.0117101
CPE carboxypeptidase E -0.0115907
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0110962
ZBTB18 zinc finger and BTB domain containing 18 -0.0107756
TMEM14B transmembrane protein 14B -0.0107194
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.0105681
KRAS Kirsten rat sarcoma viral oncogene homolog -0.0104358
NUSAP1 nucleolar and spindle associated protein 1 -0.0104352
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0104272
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.0100918
CHN2 chimerin 2 -0.0100116
HNMT histamine N-methyltransferase -0.00996339
H1-2 H1.2 linker histone, cluster member -0.00993288
CLCA1 chloride channel accessory 1 -0.00990551
RAP2A RAP2A, member of RAS oncogene family -0.00981493
CAPG capping protein (actin filament), gelsolin-like -0.00960205
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00956358
VNN1 vanin 1 -0.00952331
FCGBP Fc fragment of IgG binding protein -0.00952148
NLRP2 NLR family, pyrin domain containing 2 -0.00946134
COL6A3 collagen, type VI, alpha 3 -0.00945819
TNNT1 troponin T type 1 (skeletal, slow) -0.00941882
ITGAV integrin, alpha V -0.00939084
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00899406
PBLD phenazine biosynthesis-like protein domain containing -0.00894034
SIRT3 sirtuin 3 -0.00890075
SLC25A46 solute carrier family 25, member 46 -0.00879764
E2F2 E2F transcription factor 2 -0.0087913
FUCA1 fucosidase, alpha-L- 1, tissue -0.00875159
IL1R1 interleukin 1 receptor, type I -0.00873235
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00873086
BIK BCL2-interacting killer (apoptosis-inducing) -0.00857065
HIST1H2AC histone cluster 1, H2ac -0.00853712
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00852738
ADAMDEC1 ADAM-like, decysin 1 -0.00852067
HMGB2 high mobility group box 2 -0.00851135
MB myoglobin -0.00847377
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00844413
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00843845
MGAM maltase-glucoamylase -0.00843519
MMP9 matrix metallopeptidase 9 -0.00843222
TMEM106B transmembrane protein 106B -0.00841724
REG3A regenerating islet-derived 3 alpha -0.0084034
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0083651
REG1A regenerating islet-derived 1 alpha -0.00836018
SOCS1 suppressor of cytokine signaling 1 -0.00834946
UPP1 uridine phosphorylase 1 -0.00834467
GMPR guanosine monophosphate reductase -0.00830458
H1-0 H1.0 linker histone -0.00826687
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00817687
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00816964
WSB1 WD repeat and SOCS box containing 1 -0.00805489
FABP1 fatty acid binding protein 1, liver -0.0079794
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00796716
IRS1 insulin receptor substrate 1 -0.00794025
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00793875
ODC1 ornithine decarboxylase 1 -0.0079028
TFPI2 tissue factor pathway inhibitor 2 -0.00784373
BIRC3 baculoviral IAP repeat containing 3 -0.00779916
LYZ lysozyme -0.00775626
CTSH cathepsin H -0.00775066
HEPH hephaestin -0.00774154
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00772471
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00766692
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00765694
ALDOB aldolase B, fructose-bisphosphate -0.00764546
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00763918
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00762629
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -0.00761265
NPY neuropeptide Y -0.00757467
SLN sarcolipin -0.00757362
TSPAN5 tetraspanin 5 -0.00747572
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00745784
AZF1 azoospermia factor 1 -0.00741383
RGS2 regulator of G-protein signaling 2 -0.00741168
PCP4 Purkinje cell protein 4 -0.00739967
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00738854
PARM1 prostate androgen-regulated mucin-like protein 1 -0.00737966
RANBP1 RAN binding protein 1 -0.00735084
FKBP9 FK506 binding protein 9, 63 kDa -0.00733096
HMGN4 high mobility group nucleosomal binding domain 4 -0.00730375
CDC45 cell division cycle 45 -0.00728154
KRT20 keratin 20, type I -0.00727545
TMEM106C transmembrane protein 106C -0.00727137
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00726097
CPVL carboxypeptidase, vitellogenic-like -0.00725628
SI sucrase-isomaltase (alpha-glucosidase) -0.00722055
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00719238
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -0.00718375
MRPL57 mitochondrial ribosomal protein L57 -0.00716892
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.00715959
PDZK1IP1 PDZK1 interacting protein 1 -0.00715324
PCLO piccolo presynaptic cytomatrix protein -0.00714317
KCTD12 potassium channel tetramerization domain containing 12 -0.00713164
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00707869
LST1 leukocyte specific transcript 1 -0.00707484
EFNB2 ephrin-B2 -0.00706957
HAMP hepcidin antimicrobial peptide -0.00698906
EPHA4 EPH receptor A4 -0.0069793
COA3 cytochrome c oxidase assembly factor 3 -0.00697887
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00696541
RGS10 regulator of G-protein signaling 10 -0.00696129
ZNF124 zinc finger protein 124 -0.0069447
TFF1 trefoil factor 1 -0.00693444
DCXR dicarbonyl/L-xylulose reductase -0.00691787
APOB apolipoprotein B -0.00689966
CTSB cathepsin B -0.00689847
TBL1X transducin (beta)-like 1X-linked -0.0068969
AOC1 amine oxidase, copper containing 1 -0.00688864
ACE2 angiotensin I converting enzyme 2 -0.00687506
AMH anti-Mullerian hormone -0.00687422
AP1AR adaptor-related protein complex 1 associated regulatory protein -0.00686581
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00685594
VEGFA vascular endothelial growth factor A -0.00685203
BRCA1 breast cancer 1, early onset -0.00681952
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.0068189
FXYD2 FXYD domain containing ion transport regulator 2 -0.00681441
SYNDIG1 synapse differentiation inducing 1 -0.00681426
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -0.00680906
HSPB11 heat shock protein family B (small), member 11 -0.00679638
RBM47 RNA binding motif protein 47 -0.00678928
SLC22A18 solute carrier family 22, member 18 -0.00678258
INTS6 integrator complex subunit 6 -0.00678044
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00674283
IL17RB interleukin 17 receptor B -0.00672129
MMP12 matrix metallopeptidase 12 -0.00670484
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00668905
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00668671
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.00668289
CLEC7A C-type lectin domain family 7, member A -0.00667867
EVI2A ecotropic viral integration site 2A -0.00667636
AIM2 absent in melanoma 2 -0.0066675
CCL20 chemokine (C-C motif) ligand 20 -0.00663337
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00663168
CKM creatine kinase, muscle -0.00662882
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00660773
HIST1H2BD histone cluster 1, H2bd -0.00659653
PAGE4 P antigen family, member 4 (prostate associated) -0.0065936
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00657871
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00657509
CCNE2 cyclin E2 -0.00656784
STC2 stanniocalcin 2 -0.00655558
KAT2B K(lysine) acetyltransferase 2B -0.00654475
CALB1 calbindin 1, 28kDa -0.00653178
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00652664
SNAP29 synaptosomal-associated protein, 29kDa -0.00652044
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00651703
HTRA1 HtrA serine peptidase 1 -0.00650228
MT1X metallothionein 1X -0.00648422
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00645982
MED7 mediator complex subunit 7 -0.00644888
OSBPL8 oxysterol binding protein-like 8 -0.00643492
PDGFC platelet derived growth factor C -0.00640521
CLDN3 claudin 3 -0.00638419
KLF5 Kruppel-like factor 5 (intestinal) -0.00637671
HSPA1A heat shock 70kDa protein 1A -0.00636693
CNN1 calponin 1, basic, smooth muscle -0.00635506
DPP4 dipeptidyl-peptidase 4 -0.00635339
MME membrane metallo-endopeptidase -0.00635222
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -0.00634588
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00633438
TNNI2 troponin I type 2 (skeletal, fast) -0.00632927
ALB albumin -0.00632715
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00631927
PDLIM3 PDZ and LIM domain 3 -0.00631442
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.00630637
ACTA1 actin, alpha 1, skeletal muscle -0.00630634
S100A10 S100 calcium binding protein A10 -0.00628015
MAPK1 mitogen-activated protein kinase 1 -0.00627894
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.00627709
GREB1 growth regulation by estrogen in breast cancer 1 -0.00626714
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -0.0062647
TCL1B T-cell leukemia/lymphoma 1B -0.00624975
HIC2 hypermethylated in cancer 2 -0.00624788
CA2 carbonic anhydrase II -0.00624103
ZNF593 zinc finger protein 593 -0.00623754
WT1 Wilms tumor 1 -0.00623588
ZG16 zymogen granule protein 16 -0.00623208
LTB lymphotoxin beta (TNF superfamily, member 3) -0.006201
FLNC filamin C, gamma -0.0061914
TMEM14A transmembrane protein 14A -0.00617695
ERBIN erbb2 interacting protein -0.00617279
DES desmin -0.00617165
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00616989
MCUR1 mitochondrial calcium uniporter regulator 1 -0.00616685
TNNC2 troponin C type 2 (fast) -0.0061644
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00615835
MEA1 male-enhanced antigen 1 -0.00613952
SAR1B secretion associated, Ras related GTPase 1B -0.00613071
STAG3 stromal antigen 3 -0.00609868
PAK1IP1 PAK1 interacting protein 1 -0.00608638
CHKB choline kinase beta -0.00606618
TMEM38B transmembrane protein 38B -0.00606364
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00604877
ARF3 ADP-ribosylation factor 3 -0.00604233
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.0060258
GPATCH2 G patch domain containing 2 -0.00602296
ATOX1 antioxidant 1 copper chaperone -0.0060214
TWF1 twinfilin actin binding protein 1 -0.00602072
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00601968
UBE2C ubiquitin-conjugating enzyme E2C -0.00600764
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00599826
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00598504
PSPH phosphoserine phosphatase -0.00597793
GLIPR1 GLI pathogenesis-related 1 -0.00596303
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.00595907
CCK cholecystokinin -0.005956
CD86 CD86 molecule -0.00594577
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00590862
FGFR2 fibroblast growth factor receptor 2 -0.00590043
TCEAL4 transcription elongation factor A (SII)-like 4 -0.0058932
IGSF6 immunoglobulin superfamily, member 6 -0.00589245
SNX7 sorting nexin 7 -0.00589231
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00588483
KLF10 Kruppel-like factor 10 -0.00588336
MARCHF1 membrane associated ring-CH-type finger 1 -0.00588033
SPON2 spondin 2, extracellular matrix protein -0.00586656
HLA-DOB major histocompatibility complex, class II, DO beta -0.00586431
JAG1 jagged 1 -0.00585382
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D -0.00584697
APOA1 apolipoprotein A-I -0.00584512
YAP1 Yes-associated protein 1 -0.00583684
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00583109
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.0058035
ABHD6 abhydrolase domain containing 6 -0.00579655
NECTIN3 nectin cell adhesion molecule 3 -0.0057855
JPT1 Jupiter microtubule associated homolog 1 -0.00578226
OSTM1 osteopetrosis associated transmembrane protein 1 -0.00577518
CLEC10A C-type lectin domain family 10, member A -0.00577161
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00577044
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00575709
MAOB monoamine oxidase B -0.00575668
MINK1 misshapen-like kinase 1 -0.00575183
NRXN2 neurexin 2 -0.00574568
NDFIP1 Nedd4 family interacting protein 1 -0.00574433
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00574367
DERL2 derlin 2 -0.00574098
F13A1 coagulation factor XIII, A1 polypeptide -0.0057189
MICU2 mitochondrial calcium uptake 2 -0.00571577
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0057012
CPB1 carboxypeptidase B1 (tissue) -0.00569795
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0056893
APOC2 apolipoprotein C-II -0.00568514