PYGO2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description pygopus family PHD finger 2| (NCBI Entrez Gene Database, 90780)
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Genes

357 genes differentially expressed following the PYGO2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TRPM5 transient receptor potential cation channel, subfamily M, member 5 2.71315
HMX1 H6 family homeobox 1 2.71315
ARSH arylsulfatase family, member H 2.71315
IL5 interleukin 5 2.71315
NHLRC4 NHL repeat containing 4 2.71315
FGF7 fibroblast growth factor 7 2.71315
VCX3A variable charge, X-linked 3A 2.71315
IL23R interleukin 23 receptor 2.71315
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.71315
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.71315
TMC3 transmembrane channel-like 3 2.71315
UBA7 ubiquitin-like modifier activating enzyme 7 2.71315
PSCA prostate stem cell antigen 2.71315
CPB1 carboxypeptidase B1 (tissue) 2.71315
TMEM235 transmembrane protein 235 2.71315
HIPK4 homeodomain interacting protein kinase 4 2.71315
MUC21 mucin 21, cell surface associated 2.71315
TREML4 triggering receptor expressed on myeloid cells-like 4 2.71315
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.71315
TAS1R2 taste receptor, type 1, member 2 2.71315
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.71315
MMEL1 membrane metallo-endopeptidase-like 1 2.71315
ZPLD1 zona pellucida-like domain containing 1 2.71315
CCDC38 coiled-coil domain containing 38 2.71315
SYTL3 synaptotagmin-like 3 2.71315
GRAP2 GRB2-related adaptor protein 2 2.71315
CSAG2 CSAG family, member 2 2.71315
GATA2 GATA binding protein 2 2.71315
CD8A CD8a molecule 2.71315
SYT15 synaptotagmin XV 2.71315
PRG4 proteoglycan 4 2.71315
NPR3 natriuretic peptide receptor 3 2.71315
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 2.71315
PSD2 pleckstrin and Sec7 domain containing 2 2.71315
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 2.71315
LRRC72 leucine rich repeat containing 72 2.71315
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.71315
ZAR1L zygote arrest 1-like 2.71315
KIF19 kinesin family member 19 2.71315
CCR6 chemokine (C-C motif) receptor 6 2.71315
MS4A18 membrane-spanning 4-domains, subfamily A, member 18 2.71315
PLIN1 perilipin 1 2.71315
USH1G Usher syndrome 1G (autosomal recessive) 2.71315
BTC betacellulin 2.71315
PVRIG poliovirus receptor related immunoglobulin domain containing 2.71315
OR2A5 olfactory receptor, family 2, subfamily A, member 5 2.71315
ATP13A4 ATPase type 13A4 2.71315
PKP1 plakophilin 1 2.71315
HES3 hes family bHLH transcription factor 3 2.71315
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.71315
CELF6 CUGBP, Elav-like family member 6 2.71315
COL20A1 collagen, type XX, alpha 1 2.71315
TMEM225 transmembrane protein 225 2.71315
HLX H2.0-like homeobox 2.71315
CARD18 caspase recruitment domain family, member 18 2.71315
VWA5B2 von Willebrand factor A domain containing 5B2 2.71315
SLC26A7 solute carrier family 26 (anion exchanger), member 7 2.71315
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.71315
PTX3 pentraxin 3, long 2.71315
HORMAD1 HORMA domain containing 1 2.71315
SCRG1 stimulator of chondrogenesis 1 2.71315
MYOM3 myomesin 3 2.71315
PTPRC protein tyrosine phosphatase, receptor type, C 2.71315
LYZL6 lysozyme-like 6 2.71315
ADGB androglobin 2.71315
GADL1 glutamate decarboxylase-like 1 2.71315
CLEC3B C-type lectin domain family 3, member B 2.71315
SNPH syntaphilin 2.71315
C9ORF152 chromosome 9 open reading frame 152 2.71315
ACSL5 acyl-CoA synthetase long-chain family member 5 2.71315
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.71315
PCDHA2 protocadherin alpha 2 2.71315
SLC25A45 solute carrier family 25, member 45 2.71315
SH2D7 SH2 domain containing 7 2.71315
PROB1 proline-rich basic protein 1 2.71315
NPSR1 neuropeptide S receptor 1 2.71315
APOA2 apolipoprotein A-II 2.71315
FAM156B family with sequence similarity 156, member B 2.71315
SSMEM1 serine-rich single-pass membrane protein 1 2.71315
SLFN11 schlafen family member 11 2.71315
HHIPL2 HHIP-like 2 2.71315
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.71315
UTS2R urotensin 2 receptor 2.71315
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.71315
LY96 lymphocyte antigen 96 2.71315
RIPPLY2 ripply transcriptional repressor 2 2.71315
AJM1 apical junction component 1 homolog 2.71315
ERFE erythroferrone 2.71315
GSTA2 glutathione S-transferase alpha 2 2.71315
SPHKAP SPHK1 interactor, AKAP domain containing 2.71315
FSHR follicle stimulating hormone receptor 2.71315
RTL9 retrotransposon Gag like 9 2.71315
CLEC4C C-type lectin domain family 4, member C 2.71315
FAM237B family with sequence similarity 237 member B 2.71315
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.71315
EMP1 epithelial membrane protein 1 2.71315
CCDC198 coiled-coil domain containing 198 2.71315
IL1A interleukin 1, alpha 2.71315
CHI3L2 chitinase 3-like 2 2.71315
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.71315
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.71315
PRSS38 protease, serine, 38 2.71315
DPEP2NB DPEP2 neighbor 2.71315
ADCY4 adenylate cyclase 4 2.71315
PNMA6F PNMA family member 6F 2.71315
CXORF58 chromosome X open reading frame 58 2.71315
FKBP1C FK506 binding protein 1C 2.71315
CNGB1 cyclic nucleotide gated channel beta 1 2.71315
HSFX3 heat shock transcription factor family, X-linked member 3 2.71315
CIMIP2C ciliary microtubule inner protein 2C 2.71315
OOSP4A oocyte secreted protein family member 4A 2.71315
RASA4 RAS p21 protein activator 4 2.71315
GPR61 G protein-coupled receptor 61 2.71315
PENK proenkephalin 2.71315
H1-8 H1.8 linker histone 2.71315
PEAK3 PEAK family member 3 2.71315
ZNF593OS ZNF593 opposite strand 2.71315
C1ORF105 chromosome 1 open reading frame 105 2.71315
MSMP microseminoprotein, prostate associated 2.71315
TYR tyrosinase 2.71315
MEFV Mediterranean fever 2.71315
CHRM4 cholinergic receptor, muscarinic 4 2.71315
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.71315
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 2.71315
C17ORF107 chromosome 17 open reading frame 107 2.71315
PCDHGB5 protocadherin gamma subfamily B, 5 2.71315
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.71315
LRRC46 leucine rich repeat containing 46 2.71315
GFI1B growth factor independent 1B transcription repressor 2.71315
CCL25 chemokine (C-C motif) ligand 25 2.71315
SLFN12L schlafen family member 12-like 2.71315
DMBT1 deleted in malignant brain tumors 1 2.71315
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2.71315
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.71315
SLC7A4 solute carrier family 7, member 4 2.71315
IMPG2 interphotoreceptor matrix proteoglycan 2 2.71315
ACKR3 atypical chemokine receptor 3 2.71315
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.71315
LIMS1 LIM and senescent cell antigen-like domains 1 2.71315
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.71315
GC group-specific component (vitamin D binding protein) 2.71315
MR1 major histocompatibility complex, class I-related 2.71315
CNTF ciliary neurotrophic factor 2.71315
CPSF4L cleavage and polyadenylation specific factor 4-like 2.71315
CLDN14 claudin 14 2.71315
KLF6 Kruppel-like factor 6 2.71315
NECTIN4 nectin cell adhesion molecule 4 2.71315
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 2.71315
GOLGA6C golgin A6 family, member C 2.71315
ADAM7 ADAM metallopeptidase domain 7 2.71315
CNTNAP1 contactin associated protein 1 2.71315
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 2.71315
AQP7 aquaporin 7 2.71315
TRIM31 tripartite motif containing 31 2.71315
PLCZ1 phospholipase C, zeta 1 2.71315
ZNF703 zinc finger protein 703 2.71315
STMN4 stathmin-like 4 2.71315
EDN1 endothelin 1 2.71315
NXNL1 nucleoredoxin-like 1 2.71315
ADGRG3 adhesion G protein-coupled receptor G3 2.71315
CST1 cystatin SN 2.71315
LZTFL1 leucine zipper transcription factor-like 1 2.64328
SAXO5 stabilizer of axonemal microtubules 5 2.63938
DISP2 dispatched homolog 2 (Drosophila) 2.63938
TIPRL TOR signaling pathway regulator 2.61065
HES1 hes family bHLH transcription factor 1 2.59858
IPO7 importin 7 2.56445
TXLNB taxilin beta 2.5436
MAP3K4-AS1 MAP3K4 antisense RNA 1 2.5436
CCDC86 coiled-coil domain containing 86 2.54196
CCDC74A coiled-coil domain containing 74A 2.51923
NOP53 NOP53 ribosome biogenesis factor 2.51185
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.49893
ANKAR ankyrin and armadillo repeat containing 2.4942
RESF1 retroelement silencing factor 1 2.47433
ADPRH ADP-ribosylarginine hydrolase 2.4454
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.4404
NTS neurotensin 2.38048
WDR45 WD repeat domain 45 2.38048
TMTC4 transmembrane and tetratricopeptide repeat containing 4 2.3761
SLC16A11 solute carrier family 16, member 11 2.37236
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 2.37236
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.37236
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.37236
KLHL36 kelch-like family member 36 2.37236
MUSTN1 musculoskeletal, embryonic nuclear protein 1 2.37236
APEH acylaminoacyl-peptide hydrolase 2.35567
SEC61B Sec61 beta subunit 2.34465
LZTS3 leucine zipper, putative tumor suppressor family member 3 2.33874
ZNF610 zinc finger protein 610 2.3348
ARSJ arylsulfatase family, member J 2.31648
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.29665
WDR25 WD repeat domain 25 2.29665
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.29544
LYRM7 LYR motif containing 7 2.29387
EXOC3 exocyst complex component 3 2.29387
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.29353
SHANK1 SH3 and multiple ankyrin repeat domains 1 2.28983
IGLON5 IgLON family member 5 2.27315
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 2.26104
DTNBP1 dystrobrevin binding protein 1 2.25679
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.23893
UQCRC2 ubiquinol-cytochrome c reductase core protein II 2.23617
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 2.21916
ENG endoglin 2.20326
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.20048
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2.17073
DRAXIN dorsal inhibitory axon guidance protein 2.15343
SOCS1 suppressor of cytokine signaling 1 2.13292
OTUD1 OTU deubiquitinase 1 2.11419
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 2.11136
RASL12 RAS-like, family 12 2.11136
SHOC1 shortage in chiasmata 1 2.11136
MAN1A2 mannosidase, alpha, class 1A, member 2 2.10716
NRIP1 nuclear receptor interacting protein 1 2.10716
HMGB3 high mobility group box 3 2.08299
PHF7 PHD finger protein 7 2.07128
EEF2 eukaryotic translation elongation factor 2 2.06649
UBE3D ubiquitin protein ligase E3D 2.05666
PDE8A phosphodiesterase 8A 2.05149
PDIA3 protein disulfide isomerase family A, member 3 2.04466
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.04191
MOCS2 molybdenum cofactor synthesis 2 2.04191
PFKL phosphofructokinase, liver 2.02652
MED9 mediator complex subunit 9 2.02652
DOCK5 dedicator of cytokinesis 5 2.01772
TRUB2 TruB pseudouridine (psi) synthase family member 2 2.01731
FBXO41 F-box protein 41 2.01701
ADPRS ADP-ribosylserine hydrolase 2.00942
SLC22A15 solute carrier family 22, member 15 2.00625
PCDHB4 protocadherin beta 4 2.00584
ELAC2 elaC ribonuclease Z 2 2.00052
SYNRG synergin, gamma 2.00052

decreased expression

Symbol Name Standardized Value
H2BC8 H2B clustered histone 8 -2.71315
CPT1B carnitine palmitoyltransferase 1B (muscle) -2.71315
FMO2 flavin containing monooxygenase 2 (non-functional) -2.71315
NME5 NME/NM23 family member 5 -2.71315
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -2.71315
MSC musculin -2.71315
MROH6 maestro heat-like repeat family member 6 -2.71315
ATOH7 atonal homolog 7 (Drosophila) -2.71315
NWD2 NACHT and WD repeat domain containing 2 -2.71315
ZMAT2 zinc finger, matrin-type 2 -2.71315
ZNF568 zinc finger protein 568 -2.71315
GPR78 G protein-coupled receptor 78 -2.71315
GLB1L galactosidase, beta 1-like -2.71315
SOX30 SRY (sex determining region Y)-box 30 -2.71315
A1CF APOBEC1 complementation factor -2.71315
RPS6KL1 ribosomal protein S6 kinase-like 1 -2.71315
APLN apelin -2.71315
C8ORF48 chromosome 8 open reading frame 48 -2.71315
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.71315
TTLL13 tubulin tyrosine ligase like 13 -2.71315
SAPCD1 suppressor APC domain containing 1 -2.71315
ADPRHL1 ADP-ribosylhydrolase like 1 -2.71315
AHNAK2 AHNAK nucleoprotein 2 -2.71315
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 -2.71315
WDR64 WD repeat domain 64 -2.71315
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -2.71315
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.71315
GTSF1 gametocyte specific factor 1 -2.71315
GLIPR1L2 GLI pathogenesis-related 1 like 2 -2.71315
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -2.71315
LDHAL6A lactate dehydrogenase A-like 6A -2.71315
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -2.71315
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -2.71315
TMEM229A transmembrane protein 229A -2.71315
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 -2.71315
CXCR4 chemokine (C-X-C motif) receptor 4 -2.71315
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 -2.71315
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 -2.71315
WFDC1 WAP four-disulfide core domain 1 -2.71315
TCAP titin-cap -2.71315
LHX8 LIM homeobox 8 -2.71315
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -2.71315
CPXM1 carboxypeptidase X (M14 family), member 1 -2.71315
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -2.71315
INPP1 inositol polyphosphate-1-phosphatase -2.71315
ULK4 unc-51 like kinase 4 -2.71315
CDCA7 cell division cycle associated 7 -2.71315
SCNN1B sodium channel, non voltage gated 1 beta subunit -2.71315
TMEM200B transmembrane protein 200B -2.71315
CRYBA4 crystallin, beta A4 -2.71315
ITGA11 integrin, alpha 11 -2.71315
SNX31 sorting nexin 31 -2.71315
ZNF594 zinc finger protein 594 -2.71122
ZNF207 zinc finger protein 207 -2.69263
ADGRG6 adhesion G protein-coupled receptor G6 -2.68943
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -2.68221
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.63681
KCTD19 potassium channel tetramerization domain containing 19 -2.60263
CCDC183 coiled-coil domain containing 183 -2.60263
SACK1A scaffolding CK1 anchoring protein A -2.57198
SOX10 SRY (sex determining region Y)-box 10 -2.57198
NOXA1 NADPH oxidase activator 1 -2.57198
MXRA5 matrix-remodelling associated 5 -2.57198
TRIM47 tripartite motif containing 47 -2.57198
SCT secretin -2.57198
ZNF418 zinc finger protein 418 -2.56568
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.56292
ELOVL4 ELOVL fatty acid elongase 4 -2.55313
TMEM115 transmembrane protein 115 -2.5436
ALDOC aldolase C, fructose-bisphosphate -2.51335
CRYZ crystallin, zeta (quinone reductase) -2.51185
ZNF395 zinc finger protein 395 -2.49893
FCSK fucose kinase -2.48043
RBM4B RNA binding motif protein 4B -2.47433
ATM ATM serine/threonine kinase -2.46841
BCAS2 breast carcinoma amplified sequence 2 -2.4292
PLXNA2 plexin A2 -2.42675
MMP26 matrix metallopeptidase 26 -2.42675
NUTM1 NUT midline carcinoma, family member 1 -2.42675
EGR1 early growth response 1 -2.41615
FAM50B family with sequence similarity 50, member B -2.41615
TTPAL tocopherol (alpha) transfer protein-like -2.4144
PLP1 proteolipid protein 1 -2.40021
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 -2.35567
PNMA6A paraneoplastic Ma antigen family member 6A -2.34959
FBXW4 F-box and WD repeat domain containing 4 -2.29544
STON2 stonin 2 -2.29482
NOVA1 neuro-oncological ventral antigen 1 -2.29051
PARP8 poly (ADP-ribose) polymerase family, member 8 -2.2523
KDR kinase insert domain receptor -2.24257
H4C13 H4 clustered histone 13 -2.23665
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.23665
CEP290 centrosomal protein 290kDa -2.21477
DRC10 dynein regulatory complex subunit 10 -2.16269
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -2.15156
OAZ2 ornithine decarboxylase antizyme 2 -2.1459
GMPR guanosine monophosphate reductase -2.13595
FRAS1 Fraser extracellular matrix complex subunit 1 -2.13292
DPY19L1 dpy-19-like 1 (C. elegans) -2.12697
MPZL3 myelin protein zero-like 3 -2.12381
NUCB2 nucleobindin 2 -2.12105
ZSWIM7 zinc finger, SWIM-type containing 7 -2.11812
MSRB2 methionine sulfoxide reductase B2 -2.11812
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -2.11136
TEX11 testis expressed 11 -2.10916
RIGI RNA sensor RIG-I -2.10716
FASTKD5 FAST kinase domains 5 -2.09708
FAM234B family with sequence similarity 234 member B -2.09296
ADGRV1 adhesion G protein-coupled receptor V1 -2.092
RPL13 ribosomal protein L13 -2.08299
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.07623
CRTC2 CREB regulated transcription coactivator 2 -2.0726
RPSA ribosomal protein SA -2.07242
MAP3K21 mitogen-activated protein kinase kinase kinase 21 -2.06649
MAP2K1 mitogen-activated protein kinase kinase 1 -2.04466
TRIM56 tripartite motif containing 56 -2.03593
CHERP calcium homeostasis endoplasmic reticulum protein -2.02652
RGS17 regulator of G-protein signaling 17 -2.02652
ZBTB5 zinc finger and BTB domain containing 5 -2.02652
NFRKB nuclear factor related to kappaB binding protein -2.02222
FRMD5 FERM domain containing 5 -2.01772
TMEM208 transmembrane protein 208 -2.01752
C12ORF56 chromosome 12 open reading frame 56 -2.01731
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -2.00052