Paclitaxel Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark. (Chemical Entities of Biological Interest Ontology, CHEBI_45863)
External Link http://www.drugbank.ca/drugs/DB01229
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Genes

15 interacting proteins for the Paclitaxel drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
BCL2 B-cell CLL/lymphoma 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
MAP2 microtubule-associated protein 2
MAP4 microtubule-associated protein 4
MAPT microtubule-associated protein tau
NR1I2 nuclear receptor subfamily 1, group I, member 2
SLCO1B3 solute carrier organic anion transporter family, member 1B3
TUBB1 tubulin, beta 1 class VI