| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0998835 |
| HDAC9 | histone deacetylase 9 | 0.0833154 |
| CDH13 | cadherin 13 | 0.063569 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0626862 |
| SUCNR1 | succinate receptor 1 | 0.0548044 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0514612 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0491637 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0454456 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0451777 |
| PODXL | podocalyxin-like | 0.0430745 |
| SP100 | SP100 nuclear antigen | 0.0394872 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0394334 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0391554 |
| CALR | calreticulin | 0.0374975 |
| RND3 | Rho family GTPase 3 | 0.0362722 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0362329 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.033857 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0324639 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0318291 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0304448 |
| AHNAK | AHNAK nucleoprotein | 0.028958 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0288712 |
| INTS6 | integrator complex subunit 6 | 0.0283676 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0281109 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0275574 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0265165 |
| MSI2 | musashi RNA-binding protein 2 | 0.0253519 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0252053 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0230803 |
| VEGFC | vascular endothelial growth factor C | 0.022785 |
| TUBB | tubulin, beta class I | 0.0213749 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0212181 |
| SQSTM1 | sequestosome 1 | 0.0211909 |
| ANXA1 | annexin A1 | 0.0211341 |
| POTEF | POTE ankyrin domain family, member F | 0.0210791 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0206544 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0203837 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0202017 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0198268 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0194396 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0193407 |
| PCDH7 | protocadherin 7 | 0.0190515 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0190224 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0189018 |
| GOLGB1 | golgin B1 | 0.0187637 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0186654 |
| CLIC1 | chloride intracellular channel 1 | 0.0179604 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0178439 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0176805 |
| ENO1 | enolase 1, (alpha) | 0.0175639 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0173247 |
| CSTB | cystatin B (stefin B) | 0.0167528 |
| NAV3 | neuron navigator 3 | 0.0163163 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0162768 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0161806 |
| TLE4 | transducin-like enhancer of split 4 | 0.0160616 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0159678 |
| ACTG1 | actin gamma 1 | 0.0159622 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.01584 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0158167 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.014968 |
| PTCHD4 | patched domain containing 4 | 0.014875 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0148734 |
| PMP22 | peripheral myelin protein 22 | 0.0147947 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0147216 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0146929 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0146413 |
| GLRX | glutaredoxin (thioltransferase) | 0.0145463 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0145243 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0144845 |
| FTL | ferritin, light polypeptide | 0.0144798 |
| GPR176 | G protein-coupled receptor 176 | 0.0143968 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0142816 |
| CCND1 | cyclin D1 | 0.0141778 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0140654 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0140623 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0140382 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0140145 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0139921 |
| FMN2 | formin 2 | 0.0139064 |
| BRD2 | bromodomain containing 2 | 0.013824 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.013769 |
| RAB31 | RAB31, member RAS oncogene family | 0.0135115 |
| DST | dystonin | 0.013433 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0134183 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 0.0134147 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0134042 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0133755 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.013362 |
| FOXP1 | forkhead box P1 | 0.0133315 |
| JUN | jun proto-oncogene | 0.0132678 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0131911 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0131646 |
| TOX | thymocyte selection-associated high mobility group box | 0.013011 |
| VCL | vinculin | 0.0130007 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0127266 |
| GDF15 | growth differentiation factor 15 | 0.0126484 |
| RASAL2 | RAS protein activator like 2 | 0.0126035 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0125034 |
| TUBA1A | tubulin, alpha 1a | 0.0121454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.219736 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.158296 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.132981 |
| MT2A | metallothionein 2A | -0.113203 |
| FBN1 | fibrillin 1 | -0.111447 |
| PLAT | plasminogen activator, tissue | -0.0905063 |
| LOXL2 | lysyl oxidase-like 2 | -0.0887127 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0812687 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0804972 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0790398 |
| FLNB | filamin B, beta | -0.0751759 |
| CD44 | CD44 molecule (Indian blood group) | -0.0728767 |
| NAV1 | neuron navigator 1 | -0.0675507 |
| TMSB10 | thymosin beta 10 | -0.0647658 |
| SBF2 | SET binding factor 2 | -0.0644579 |
| MYOF | myoferlin | -0.0613005 |
| COL1A2 | collagen, type I, alpha 2 | -0.0603459 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0583963 |
| COL5A2 | collagen, type V, alpha 2 | -0.0561937 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0516654 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0504243 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0503042 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0449708 |
| GPC6 | glypican 6 | -0.0442443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0441713 |
| RUNX1 | runt-related transcription factor 1 | -0.0441325 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.044054 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0440389 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0418219 |
| NDRG1 | N-myc downstream regulated 1 | -0.0416997 |
| COL3A1 | collagen, type III, alpha 1 | -0.0411148 |
| SETD5 | SET domain containing 5 | -0.0408799 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0407786 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0405494 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0401505 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0400859 |
| VIM | vimentin | -0.0392224 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0388949 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0388575 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0387592 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0387555 |
| ATP13A3 | ATPase type 13A3 | -0.0374178 |
| B2M | beta-2-microglobulin | -0.0354583 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0353102 |
| ZNF292 | zinc finger protein 292 | -0.0350908 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.034974 |
| RAI14 | retinoic acid induced 14 | -0.0347845 |
| SP3 | Sp3 transcription factor | -0.0347806 |
| UBC | ubiquitin C | -0.0339894 |
| SVIL | supervillin | -0.0337065 |
| SEPTIN9 | septin 9 | -0.0335705 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0334276 |
| MAP4 | microtubule-associated protein 4 | -0.0331843 |
| OGA | O-GlcNAcase | -0.0327498 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0324379 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0324114 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0322218 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0320702 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0304957 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0304632 |
| MB21D2 | Mab-21 domain containing 2 | -0.0294785 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0287965 |
| RASA2 | RAS p21 protein activator 2 | -0.0284409 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.028002 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0278029 |
| GLIS3 | GLIS family zinc finger 3 | -0.0277245 |
| RTN4 | reticulon 4 | -0.0272841 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0269754 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0266329 |
| YEATS2 | YEATS domain containing 2 | -0.0266247 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0266227 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0265933 |
| PRKD3 | protein kinase D3 | -0.0261209 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0259745 |
| CLU | clusterin | -0.0255724 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0250603 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0250207 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0250109 |
| RBM25 | RNA binding motif protein 25 | -0.0247717 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0247481 |
| AFAP1 | actin filament associated protein 1 | -0.0247437 |
| XPO1 | exportin 1 | -0.024689 |
| TMOD1 | tropomodulin 1 | -0.0245777 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0244559 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0240937 |
| ANO6 | anoctamin 6 | -0.0237584 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0234601 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0232493 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0232221 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0231172 |
| RNF24 | ring finger protein 24 | -0.0230944 |
| MT1X | metallothionein 1X | -0.0228989 |
| HELZ | helicase with zinc finger | -0.0228336 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0228029 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0226204 |
| USP34 | ubiquitin specific peptidase 34 | -0.0226062 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0224129 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0223292 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0223195 |
| NKTR | natural killer cell triggering receptor | -0.0222215 |
