| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.182528 |
| AREG | amphiregulin | 0.157774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.144096 |
| NLGN1 | neuroligin 1 | 0.0925595 |
| PCDH7 | protocadherin 7 | 0.0839482 |
| DST | dystonin | 0.0835391 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0810686 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0655758 |
| HMGA2 | high mobility group AT-hook 2 | 0.0610838 |
| PCBP2 | poly(rC) binding protein 2 | 0.0594926 |
| RTN4 | reticulon 4 | 0.0583249 |
| FTL | ferritin, light polypeptide | 0.0532012 |
| DENND5A | DENN/MADD domain containing 5A | 0.0524394 |
| TUBA1B | tubulin, alpha 1b | 0.0513058 |
| POTEF | POTE ankyrin domain family, member F | 0.0484133 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0478882 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0474922 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0464702 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.045171 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0439475 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0434893 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.043143 |
| BRD2 | bromodomain containing 2 | 0.0430537 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0427955 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0418423 |
| INTS6 | integrator complex subunit 6 | 0.041483 |
| RPS12 | ribosomal protein S12 | 0.040977 |
| CCN2 | cellular communication network factor 2 | 0.0406284 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0403982 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0400907 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0395695 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0391808 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0391739 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0391681 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0390958 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0388873 |
| USP53 | ubiquitin specific peptidase 53 | 0.0387184 |
| MATR3 | matrin 3 | 0.038592 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0381494 |
| YAP1 | Yes-associated protein 1 | 0.0380771 |
| RPL37A | ribosomal protein L37a | 0.0376913 |
| CPOX | coproporphyrinogen oxidase | 0.0375996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0371813 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0370606 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0367627 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.036477 |
| RPL9 | ribosomal protein L9 | 0.0362928 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0354481 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0352589 |
| TXNRD1 | thioredoxin reductase 1 | 0.0350748 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0349032 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0344658 |
| CANX | calnexin | 0.0343636 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0336844 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0336089 |
| IPO7 | importin 7 | 0.0333396 |
| EXOC6B | exocyst complex component 6B | 0.0322622 |
| TUBA1A | tubulin, alpha 1a | 0.0320593 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0319686 |
| CALR | calreticulin | 0.0316406 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0316262 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0313021 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0310165 |
| DTNA | dystrobrevin, alpha | 0.0307334 |
| RCC1 | regulator of chromosome condensation 1 | 0.0307268 |
| HLA-A | major histocompatibility complex, class I, A | 0.0301542 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0295504 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0294836 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0294202 |
| EDN1 | endothelin 1 | 0.0293551 |
| ZNF407 | zinc finger protein 407 | 0.0290925 |
| XPOT | exportin, tRNA | 0.0281154 |
| TUBB6 | tubulin, beta 6 class V | 0.0279858 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0279641 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0276068 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0275932 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270126 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0261555 |
| LDHB | lactate dehydrogenase B | 0.0255622 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0255469 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0254539 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0252681 |
| RPL3 | ribosomal protein L3 | 0.0252035 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0250362 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0248524 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.024817 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0247835 |
| RLF | rearranged L-myc fusion | 0.024673 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0246608 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0246451 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0246045 |
| DENND5B | DENN/MADD domain containing 5B | 0.0244463 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0241568 |
| USP47 | ubiquitin specific peptidase 47 | 0.024156 |
| PRKCE | protein kinase C, epsilon | 0.0240968 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0240217 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0239171 |
| RYK | receptor-like tyrosine kinase | 0.0238891 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0238779 |
| RPS2 | ribosomal protein S2 | 0.023784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0934545 |
| VCL | vinculin | -0.0780082 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0755519 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0703127 |
| MMP12 | matrix metallopeptidase 12 | -0.0655095 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0584821 |
| EGR1 | early growth response 1 | -0.056601 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0561948 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0552896 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.053315 |
| ZNF217 | zinc finger protein 217 | -0.0522314 |
| BCHE | butyrylcholinesterase | -0.0485138 |
| ECT2 | epithelial cell transforming 2 | -0.0484639 |
| TMSB10 | thymosin beta 10 | -0.047756 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0475877 |
| EDARADD | EDAR-associated death domain | -0.0468573 |
| H1-0 | H1.0 linker histone | -0.0465009 |
| TMEM123 | transmembrane protein 123 | -0.044616 |
| PTMA | prothymosin, alpha | -0.044259 |
| MTAP | methylthioadenosine phosphorylase | -0.0441738 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.042728 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0423726 |
| EHBP1 | EH domain binding protein 1 | -0.0421939 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0421202 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0418416 |
| HDLBP | high density lipoprotein binding protein | -0.0414523 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0407882 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0388457 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0385032 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0359888 |
| CDK17 | cyclin-dependent kinase 17 | -0.0351776 |
| SYT1 | synaptotagmin I | -0.0342914 |
| JMJD1C | jumonji domain containing 1C | -0.0342351 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0341237 |
| ATG12 | autophagy related 12 | -0.0326494 |
| FBXO11 | F-box protein 11 | -0.0320358 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0320269 |
| MGAT4C | MGAT4 family, member C | -0.0318852 |
| PCNX4 | pecanex 4 | -0.0314147 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0311679 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0311379 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0310403 |
| CEP95 | centrosomal protein 95kDa | -0.0307243 |
| CLTC | clathrin, heavy chain (Hc) | -0.0306762 |
| OXR1 | oxidation resistance 1 | -0.0299454 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0297409 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0293762 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0292311 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0292163 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.0282465 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028088 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0276315 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275498 |
| KIF18A | kinesin family member 18A | -0.027333 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0272728 |
| RBL1 | retinoblastoma-like 1 | -0.0271395 |
| PREPL | prolyl endopeptidase-like | -0.0269924 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0269532 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0268072 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0266871 |
| KIAA1328 | KIAA1328 | -0.026474 |
| VMP1 | vacuole membrane protein 1 | -0.026461 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0264096 |
| PTMS | parathymosin | -0.0263697 |
| KLF6 | Kruppel-like factor 6 | -0.0261801 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.0259633 |
| POU2F1 | POU class 2 homeobox 1 | -0.0258269 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0257002 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0255439 |
| RRM2 | ribonucleotide reductase M2 | -0.0254905 |
| SMYD3 | SET and MYND domain containing 3 | -0.0253429 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0253146 |
| DIAPH3 | diaphanous-related formin 3 | -0.02525 |
| TMEM41B | transmembrane protein 41B | -0.0249876 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0249569 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0249182 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0248857 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245624 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0245319 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0243581 |
| EPHA5 | EPH receptor A5 | -0.0243145 |
| BRCA1 | breast cancer 1, early onset | -0.024166 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0241332 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0237482 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0237305 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0235817 |
| STIL | SCL/TAL1 interrupting locus | -0.0235199 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0233326 |
| RAD51B | RAD51 paralog B | -0.0231169 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0230799 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0224373 |
| GASK1B | golgi associated kinase 1B | -0.0223033 |
| RPL26 | ribosomal protein L26 | -0.0222643 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0220165 |
| ATF6 | activating transcription factor 6 | -0.0215826 |
| RPL6 | ribosomal protein L6 | -0.0214945 |
| RPL23 | ribosomal protein L23 | -0.0213226 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0213151 |
| WASF2 | WAS protein family, member 2 | -0.0213108 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.021143 |
