| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Paclitaxel_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | 0.191781 |
| EXT1 | exostosin glycosyltransferase 1 | 0.154322 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.136501 |
| INTS6 | integrator complex subunit 6 | 0.127854 |
| MACC1 | metastasis associated in colon cancer 1 | 0.124293 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.100851 |
| VCL | vinculin | 0.100601 |
| DST | dystonin | 0.0941903 |
| LMO7 | LIM domain 7 | 0.0867913 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0832029 |
| KYNU | kynureninase | 0.0795163 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0783795 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0742508 |
| MX1 | MX dynamin-like GTPase 1 | 0.0720424 |
| RIGI | RNA sensor RIG-I | 0.0717257 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0702286 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0699397 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0698876 |
| SP100 | SP100 nuclear antigen | 0.0690965 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0682068 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0679914 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.067607 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0670632 |
| DUSP16 | dual specificity phosphatase 16 | 0.0666465 |
| HKDC1 | hexokinase domain containing 1 | 0.0660604 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0649276 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0644768 |
| PLSCR2 | phospholipid scramblase 2 | 0.0631925 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.062712 |
| VMP1 | vacuole membrane protein 1 | 0.0617382 |
| MUC13 | mucin 13, cell surface associated | 0.0591443 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0559719 |
| TJP1 | tight junction protein 1 | 0.0558114 |
| PDZD8 | PDZ domain containing 8 | 0.0550661 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0542252 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0541024 |
| MX2 | MX dynamin-like GTPase 2 | 0.053993 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0528717 |
| LYZ | lysozyme | 0.0522951 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0515682 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0513791 |
| SIK3 | SIK family kinase 3 | 0.0504844 |
| ZNF292 | zinc finger protein 292 | 0.049896 |
| FNIP2 | folliculin interacting protein 2 | 0.0487714 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0482479 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0471337 |
| ETV6 | ets variant 6 | 0.0448434 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0442978 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0439756 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0426968 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0423075 |
| JAK1 | Janus kinase 1 | 0.0411173 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0409662 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0408055 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0404128 |
| MYO5B | myosin VB | 0.039837 |
| MUC20 | mucin 20, cell surface associated | 0.0393864 |
| MYO1E | myosin IE | 0.0387111 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0386272 |
| FNIP1 | folliculin interacting protein 1 | 0.0386015 |
| TOX3 | TOX high mobility group box family member 3 | 0.0383746 |
| UBAP2 | ubiquitin associated protein 2 | 0.0362491 |
| RBM47 | RNA binding motif protein 47 | 0.0361176 |
| SERINC5 | serine incorporator 5 | 0.0360961 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.035718 |
| TRIM2 | tripartite motif containing 2 | 0.0356067 |
| PHF3 | PHD finger protein 3 | 0.035476 |
| SYT1 | synaptotagmin I | 0.0352052 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.035178 |
| MECOM | MDS1 and EVI1 complex locus | 0.0349143 |
| OCLN | occludin | 0.034315 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.034226 |
| PLSCR1 | phospholipid scramblase 1 | 0.0340863 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0337525 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0335448 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0331892 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0323875 |
| TUFT1 | tuftelin 1 | 0.0322592 |
| ITGB8 | integrin, beta 8 | 0.0321775 |
| NABP1 | nucleic acid binding protein 1 | 0.0318405 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0315668 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0312768 |
| POF1B | premature ovarian failure, 1B | 0.0308772 |
| DUSP10 | dual specificity phosphatase 10 | 0.0308548 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0308534 |
| JUN | jun proto-oncogene | 0.0303854 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0303113 |
| CLOCK | clock circadian regulator | 0.0302363 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0298026 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0297604 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | 0.02975 |
| RAD51B | RAD51 paralog B | 0.0294912 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0291621 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0289715 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0286232 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0281187 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0279186 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0277905 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0275809 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0270562 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.148175 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.13735 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125408 |
| B2M | beta-2-microglobulin | -0.102117 |
| ITGA6 | integrin, alpha 6 | -0.0904272 |
| EZR | ezrin | -0.0792702 |
| TXNIP | thioredoxin interacting protein | -0.0707667 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0703329 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0630936 |
| ABHD2 | abhydrolase domain containing 2 | -0.0622617 |
| EGR1 | early growth response 1 | -0.0606836 |
| EFNB2 | ephrin-B2 | -0.0581098 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0571378 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0566787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0551315 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0534778 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0533953 |
| RNF149 | ring finger protein 149 | -0.053251 |
| ASPH | aspartate beta-hydroxylase | -0.0527276 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0525836 |
| NDRG1 | N-myc downstream regulated 1 | -0.0510992 |
| H1-0 | H1.0 linker histone | -0.04996 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0485694 |
| RUNX1 | runt-related transcription factor 1 | -0.0478951 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0446173 |
| SPATA13 | spermatogenesis associated 13 | -0.0444326 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.043627 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0421856 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0413852 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0412925 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0411483 |
| WDR45B | WD repeat domain 45B | -0.0387771 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0370767 |
| TRERF1 | transcriptional regulating factor 1 | -0.0361957 |
| AFF1 | AF4/FMR2 family, member 1 | -0.035573 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0349804 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0349434 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0348258 |
| ATP11A | ATPase, class VI, type 11A | -0.034758 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0347257 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0344607 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.034214 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0342048 |
| ENO1 | enolase 1, (alpha) | -0.0340808 |
| PGK1 | phosphoglycerate kinase 1 | -0.0340092 |
| S100A10 | S100 calcium binding protein A10 | -0.0335115 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0334809 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0331668 |
| MEIS2 | Meis homeobox 2 | -0.0330683 |
| ABLIM1 | actin binding LIM protein 1 | -0.0325264 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0324998 |
| HLA-B | major histocompatibility complex, class I, B | -0.0324295 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0324185 |
| PTMA | prothymosin, alpha | -0.0321687 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.031952 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0317533 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0316238 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.031436 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0305736 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0303008 |
| YBX3 | Y box binding protein 3 | -0.0302976 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0301029 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0295983 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0292505 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.029185 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0289799 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0287249 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0284833 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0283448 |
| PTEN | phosphatase and tensin homolog | -0.0282023 |
| S100A6 | S100 calcium binding protein A6 | -0.0268397 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0266538 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0265971 |
| CCNL1 | cyclin L1 | -0.0265683 |
| PKM | pyruvate kinase, muscle | -0.0264934 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0264667 |
| TJP2 | tight junction protein 2 | -0.0261835 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0259438 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0256455 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0254788 |
| GNAS | GNAS complex locus | -0.0252939 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0247602 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0240384 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239971 |
| CDCP1 | CUB domain containing protein 1 | -0.0239358 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0239296 |
| UBAC2 | UBA domain containing 2 | -0.0238777 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0236064 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0235378 |
| EPHB2 | EPH receptor B2 | -0.0234869 |
| BMP4 | bone morphogenetic protein 4 | -0.0232663 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0230617 |
| IRS2 | insulin receptor substrate 2 | -0.0229705 |
| SDC4 | syndecan 4 | -0.0229011 |
| MT2A | metallothionein 2A | -0.0227004 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0225703 |
| ZNF395 | zinc finger protein 395 | -0.0223254 |
| AHI1 | Abelson helper integration site 1 | -0.0222413 |
| IL20RA | interleukin 20 receptor, alpha | -0.0222099 |
| SLC38A1 | solute carrier family 38, member 1 | -0.02211 |