| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.217269 |
| FN1 | fibronectin 1 | 0.175284 |
| CDH13 | cadherin 13 | 0.110294 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0722632 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0700143 |
| STC1 | stanniocalcin 1 | 0.0675043 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0606099 |
| HMGA2 | high mobility group AT-hook 2 | 0.0528306 |
| RND3 | Rho family GTPase 3 | 0.0510607 |
| SP100 | SP100 nuclear antigen | 0.0484033 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0440965 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.043935 |
| RIGI | RNA sensor RIG-I | 0.0432182 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0426132 |
| CLMP | CXADR-like membrane protein | 0.0420722 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0384899 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0384043 |
| FNIP1 | folliculin interacting protein 1 | 0.0382957 |
| APP | amyloid beta (A4) precursor protein | 0.0368191 |
| TUBB | tubulin, beta class I | 0.0358397 |
| IL6ST | interleukin 6 signal transducer | 0.035311 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0348895 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0319375 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0314914 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0313041 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0311315 |
| BRD2 | bromodomain containing 2 | 0.0304765 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0296301 |
| NAV2 | neuron navigator 2 | 0.0292916 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0292265 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0283721 |
| GOLGB1 | golgin B1 | 0.0282913 |
| CLIC4 | chloride intracellular channel 4 | 0.0282403 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0282369 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0282022 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0278125 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0275125 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0274592 |
| VCL | vinculin | 0.0274293 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0273103 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0268535 |
| VMP1 | vacuole membrane protein 1 | 0.0266583 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0258363 |
| FBN1 | fibrillin 1 | 0.0254081 |
| PLSCR1 | phospholipid scramblase 1 | 0.024864 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0248422 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0238512 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0233566 |
| CTSB | cathepsin B | 0.0228337 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0228077 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0223446 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0211826 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0206662 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0205798 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0205393 |
| HLA-E | major histocompatibility complex, class I, E | 0.0199419 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0197132 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0194735 |
| HLA-A | major histocompatibility complex, class I, A | 0.0191924 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0191474 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0188902 |
| CMIP | c-Maf inducing protein | 0.0188492 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0185184 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0184835 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0184314 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0183629 |
| XYLT1 | xylosyltransferase I | 0.0179749 |
| ATL1 | atlastin GTPase 1 | 0.0178916 |
| EFNA5 | ephrin-A5 | 0.0176896 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0175662 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0175127 |
| RPS2 | ribosomal protein S2 | 0.0175073 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0174692 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0173699 |
| IFI44L | interferon-induced protein 44-like | 0.0173012 |
| PGM3 | phosphoglucomutase 3 | 0.0169981 |
| IFI44 | interferon-induced protein 44 | 0.0169129 |
| ANO10 | anoctamin 10 | 0.0168797 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.016818 |
| ZNF644 | zinc finger protein 644 | 0.0167921 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0167599 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0167028 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0166242 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0165833 |
| ASPH | aspartate beta-hydroxylase | 0.0165041 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.016438 |
| NRP1 | neuropilin 1 | 0.016327 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0161607 |
| NUMB | numb homolog (Drosophila) | 0.01616 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0160677 |
| TAPBP | TAP binding protein (tapasin) | 0.0160529 |
| CDK13 | cyclin-dependent kinase 13 | 0.0158374 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.015789 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0156926 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0156667 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0155218 |
| TRIM22 | tripartite motif containing 22 | 0.0154369 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0154255 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0152196 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0150493 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.206582 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.142258 |
| VIM | vimentin | -0.137471 |
| NDRG1 | N-myc downstream regulated 1 | -0.12823 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.123409 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120506 |
| TMSB10 | thymosin beta 10 | -0.112453 |
| COL1A1 | collagen, type I, alpha 1 | -0.0983607 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0859881 |
| MT2A | metallothionein 2A | -0.0808344 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.075908 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0698932 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0648361 |
| IER3 | immediate early response 3 | -0.0644806 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0636029 |
| PTMA | prothymosin, alpha | -0.0550875 |
| FTL | ferritin, light polypeptide | -0.0503417 |
| ZNF292 | zinc finger protein 292 | -0.0457878 |
| MAP1B | microtubule-associated protein 1B | -0.0447682 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0447467 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0441617 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.043713 |
| S100A9 | S100 calcium binding protein A9 | -0.0424546 |
| ATP13A3 | ATPase type 13A3 | -0.0418895 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0404916 |
| MT1X | metallothionein 1X | -0.0397305 |
| RRBP1 | ribosome binding protein 1 | -0.0393935 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0383877 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0370869 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0358448 |
| ANXA2 | annexin A2 | -0.0343564 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.034129 |
| QKI | QKI, KH domain containing, RNA binding | -0.0336818 |
| RUNX1 | runt-related transcription factor 1 | -0.0322844 |
| RLF | rearranged L-myc fusion | -0.031118 |
| COL5A1 | collagen, type V, alpha 1 | -0.030704 |
| S100A10 | S100 calcium binding protein A10 | -0.0306471 |
| USP3 | ubiquitin specific peptidase 3 | -0.0305516 |
| TMSB4X | thymosin beta 4, X-linked | -0.0302248 |
| RPL35A | ribosomal protein L35a | -0.0301074 |
| PFN1 | profilin 1 | -0.0295492 |
| PGK1 | phosphoglycerate kinase 1 | -0.0291823 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0290474 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0290265 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0280106 |
| LMNA | lamin A/C | -0.0276856 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0276174 |
| RPL23 | ribosomal protein L23 | -0.0275938 |
| S100A6 | S100 calcium binding protein A6 | -0.0272705 |
| RPL8 | ribosomal protein L8 | -0.0263857 |
| RPS8 | ribosomal protein S8 | -0.0263355 |
| CD44 | CD44 molecule (Indian blood group) | -0.0258855 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0257786 |
| DSTN | destrin (actin depolymerizing factor) | -0.0257518 |
| ANKRD28 | ankyrin repeat domain 28 | -0.025678 |
| SMAD3 | SMAD family member 3 | -0.0253937 |
| RPS19 | ribosomal protein S19 | -0.0250174 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0248309 |
| EGR1 | early growth response 1 | -0.0245538 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0240481 |
| MYOF | myoferlin | -0.0238407 |
| SEPTIN7 | septin 7 | -0.0238196 |
| SBF2 | SET binding factor 2 | -0.0237122 |
| RPL18 | ribosomal protein L18 | -0.0235918 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0232635 |
| ACTN4 | actinin, alpha 4 | -0.0232441 |
| FAM162A | family with sequence similarity 162, member A | -0.0230182 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0229084 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0222474 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0222304 |
| KLF6 | Kruppel-like factor 6 | -0.0221922 |
| RPL19 | ribosomal protein L19 | -0.0220854 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0219702 |
| GOLGA4 | golgin A4 | -0.0218835 |
| RPL32 | ribosomal protein L32 | -0.0218089 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0215532 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0212528 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0211759 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0210137 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0202613 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0202519 |
| CAVIN1 | caveolae associated protein 1 | -0.0202113 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0200021 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0198883 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.019871 |
| RPL12 | ribosomal protein L12 | -0.0198066 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0197769 |
| TGFB1 | transforming growth factor, beta 1 | -0.0196786 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0196479 |
| WASF2 | WAS protein family, member 2 | -0.019556 |
| B2M | beta-2-microglobulin | -0.0195062 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0193722 |
| GNAS | GNAS complex locus | -0.0191372 |
| MLF1 | myeloid leukemia factor 1 | -0.0190688 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0189939 |
| BBX | bobby sox homolog (Drosophila) | -0.0189713 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0188878 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0188286 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0187942 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0187778 |
