| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.113371 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0817843 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0813564 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0582365 |
| HLA-E | major histocompatibility complex, class I, E | 0.0545397 |
| B2M | beta-2-microglobulin | 0.0494161 |
| HLA-B | major histocompatibility complex, class I, B | 0.0487564 |
| SP100 | SP100 nuclear antigen | 0.0474585 |
| IFI44L | interferon-induced protein 44-like | 0.0470684 |
| PALLD | palladin, cytoskeletal associated protein | 0.0451558 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.044135 |
| DOK5 | docking protein 5 | 0.04392 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.042538 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0417286 |
| PLPP1 | phospholipid phosphatase 1 | 0.041377 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0411425 |
| FTL | ferritin, light polypeptide | 0.0405093 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0402725 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0384768 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.037307 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0362378 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0359954 |
| SQSTM1 | sequestosome 1 | 0.0356832 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0355964 |
| MT1E | metallothionein 1E | 0.0345093 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0343724 |
| RPS8 | ribosomal protein S8 | 0.0342945 |
| AOPEP | aminopeptidase O (putative) | 0.0342694 |
| ITGB8 | integrin, beta 8 | 0.0336638 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0325108 |
| HLA-A | major histocompatibility complex, class I, A | 0.0322145 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0320221 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0318951 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0318395 |
| INTS6 | integrator complex subunit 6 | 0.0318181 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0312494 |
| RPL37 | ribosomal protein L37 | 0.0308664 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0307817 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.030713 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0294484 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0288547 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0274608 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0272824 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0272328 |
| RPL35A | ribosomal protein L35a | 0.0272224 |
| ATF4 | activating transcription factor 4 | 0.0271967 |
| RPS25 | ribosomal protein S25 | 0.0269217 |
| KYNU | kynureninase | 0.0265406 |
| RPS12 | ribosomal protein S12 | 0.0265251 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.026179 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0258927 |
| TGM2 | transglutaminase 2 | 0.0250903 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0244251 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0241456 |
| RPL4 | ribosomal protein L4 | 0.0240217 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0238132 |
| RPS13 | ribosomal protein S13 | 0.0237834 |
| RPL12 | ribosomal protein L12 | 0.0237168 |
| HDAC9 | histone deacetylase 9 | 0.0235694 |
| FNIP1 | folliculin interacting protein 1 | 0.0235178 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.023214 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0230999 |
| MXRA5 | matrix-remodelling associated 5 | 0.0229029 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0224918 |
| TAPBP | TAP binding protein (tapasin) | 0.0221712 |
| NBEA | neurobeachin | 0.0217925 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0212543 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0211459 |
| RPL31 | ribosomal protein L31 | 0.0210672 |
| MX1 | MX dynamin-like GTPase 1 | 0.021016 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0210125 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0209322 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0206907 |
| DSPP | dentin sialophosphoprotein | 0.0204775 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0204625 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0203831 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0201924 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.020031 |
| BRD2 | bromodomain containing 2 | 0.0197689 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0195 |
| TUBB | tubulin, beta class I | 0.0193361 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0192308 |
| RPL26 | ribosomal protein L26 | 0.0192186 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0190182 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0189612 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0189103 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0187279 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0187154 |
| MT2A | metallothionein 2A | 0.0186998 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0186887 |
| CLIC4 | chloride intracellular channel 4 | 0.0184993 |
| APOL6 | apolipoprotein L, 6 | 0.0184334 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0183767 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0183436 |
| LYST | lysosomal trafficking regulator | 0.0183267 |
| OPTN | optineurin | 0.0183053 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0182082 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0180591 |
| MYO1E | myosin IE | 0.0180532 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0179372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.279111 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.201027 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.17448 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.136108 |
| DPYD | dihydropyrimidine dehydrogenase | -0.121606 |
| NDRG1 | N-myc downstream regulated 1 | -0.120894 |
| MYO10 | myosin X | -0.0994188 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0917894 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0885608 |
| MYOF | myoferlin | -0.0881724 |
| EMP1 | epithelial membrane protein 1 | -0.085996 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0846653 |
| ASPH | aspartate beta-hydroxylase | -0.0844406 |
| SULF1 | sulfatase 1 | -0.080002 |
| ITGA6 | integrin, alpha 6 | -0.0779981 |
| MSN | moesin | -0.0772515 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0741019 |
| ANLN | anillin, actin binding protein | -0.0739677 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0699876 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0681998 |
| HMGA2 | high mobility group AT-hook 2 | -0.0681509 |
| CD44 | CD44 molecule (Indian blood group) | -0.0674583 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0653127 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0652001 |
| CUL4B | cullin 4B | -0.0644876 |
| EZR | ezrin | -0.0640087 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0635903 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0621824 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0606648 |
| BCL2L1 | BCL2-like 1 | -0.0590778 |
| FN1 | fibronectin 1 | -0.0581378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0575259 |
| AHNAK | AHNAK nucleoprotein | -0.0569782 |
| LMNA | lamin A/C | -0.0559349 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0558489 |
| SBF2 | SET binding factor 2 | -0.055829 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0546024 |
| CDK6 | cyclin-dependent kinase 6 | -0.0544607 |
| ACTN4 | actinin, alpha 4 | -0.0527253 |
| RBM39 | RNA binding motif protein 39 | -0.0526762 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0516761 |
| POTEF | POTE ankyrin domain family, member F | -0.0512608 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.051105 |
| TMSB4X | thymosin beta 4, X-linked | -0.0509387 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.050584 |
| RIN2 | Ras and Rab interactor 2 | -0.0497057 |
| CAPRIN2 | caprin family member 2 | -0.0490001 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0489639 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0487791 |
| DIAPH3 | diaphanous-related formin 3 | -0.0486219 |
| SMAD3 | SMAD family member 3 | -0.0484733 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0478859 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0477202 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0456118 |
| CRACDL | CRACD like | -0.0444754 |
| TPX2 | TPX2, microtubule-associated | -0.0443588 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.044222 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0437705 |
| C4BPB | complement component 4 binding protein, beta | -0.0435632 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0427428 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0413366 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.040903 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0399353 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.039298 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0389946 |
| ZNF292 | zinc finger protein 292 | -0.038427 |
| FLNA | filamin A, alpha | -0.0383236 |
| PLS3 | plastin 3 | -0.0383033 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0381057 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0380048 |
| RASAL2 | RAS protein activator like 2 | -0.0379273 |
| PKM | pyruvate kinase, muscle | -0.0372531 |
| STC1 | stanniocalcin 1 | -0.0372344 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0368862 |
| NRG1 | neuregulin 1 | -0.0365189 |
| JMJD1C | jumonji domain containing 1C | -0.0364976 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0359065 |
| EFHD2 | EF-hand domain family, member D2 | -0.0355427 |
| DOCK9 | dedicator of cytokinesis 9 | -0.035435 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.035251 |
| CENPF | centromere protein F, 350/400kDa | -0.0348358 |
| LAMC2 | laminin, gamma 2 | -0.0347575 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0346242 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0343043 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0340779 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0340293 |
| SPAG9 | sperm associated antigen 9 | -0.0339971 |
| PLEC | plectin | -0.0339234 |
| GOLGA4 | golgin A4 | -0.0331741 |
| PRSS23 | protease, serine, 23 | -0.033083 |
| TOP1 | topoisomerase (DNA) I | -0.0329951 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.032919 |
| OGA | O-GlcNAcase | -0.0327952 |
| KIAA0040 | KIAA0040 | -0.0327464 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0319955 |
| ACTN1 | actinin, alpha 1 | -0.0319734 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0319163 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0316005 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.031585 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0314615 |
