| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0814476 |
| GPHN | gephyrin | 0.0792585 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0547867 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0530188 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0510011 |
| NEBL | nebulette | 0.0474469 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0468527 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.046257 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0435613 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0428611 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0386736 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0351681 |
| HSPA8 | heat shock 70kDa protein 8 | 0.034567 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0331805 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.032907 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0317514 |
| PHF3 | PHD finger protein 3 | 0.0310005 |
| GOLGA4 | golgin A4 | 0.0301643 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0299622 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0297251 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0296001 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0290147 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0286618 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0283685 |
| FOXP2 | forkhead box P2 | 0.0282109 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0280273 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0276506 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0275003 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0274936 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0273361 |
| RBM39 | RNA binding motif protein 39 | 0.0273161 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0272681 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0270403 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0268888 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0264256 |
| CANX | calnexin | 0.0262606 |
| TRIM2 | tripartite motif containing 2 | 0.0250324 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0249696 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0248656 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0247502 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0245775 |
| DSCAM | Down syndrome cell adhesion molecule | 0.024574 |
| JAK1 | Janus kinase 1 | 0.0244312 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0239526 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.023503 |
| PIGR | polymeric immunoglobulin receptor | 0.0234747 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.023429 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0234118 |
| AEBP2 | AE binding protein 2 | 0.0232782 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0231102 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0230096 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0229069 |
| MLEC | malectin | 0.022904 |
| OGA | O-GlcNAcase | 0.0227825 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0224514 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0223835 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0222747 |
| CALR | calreticulin | 0.0220679 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0220557 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0220192 |
| MECOM | MDS1 and EVI1 complex locus | 0.0220083 |
| PAPOLA | poly(A) polymerase alpha | 0.0217561 |
| RPL4 | ribosomal protein L4 | 0.0215296 |
| ZNRF3 | zinc and ring finger 3 | 0.0215216 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0213095 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0212948 |
| CTBP2 | C-terminal binding protein 2 | 0.0212487 |
| FOXP1 | forkhead box P1 | 0.0210706 |
| FNIP1 | folliculin interacting protein 1 | 0.0210693 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0209458 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0208933 |
| XPOT | exportin, tRNA | 0.0208574 |
| COG5 | component of oligomeric golgi complex 5 | 0.0206131 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.020535 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0203694 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0203437 |
| TOX | thymocyte selection-associated high mobility group box | 0.020306 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.020253 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0200889 |
| POF1B | premature ovarian failure, 1B | 0.0200533 |
| RPS2 | ribosomal protein S2 | 0.019925 |
| PTEN | phosphatase and tensin homolog | 0.0198778 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0195946 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0195205 |
| BRD2 | bromodomain containing 2 | 0.0194948 |
| SMAD2 | SMAD family member 2 | 0.0193935 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0193637 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0192211 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0191001 |
| SQSTM1 | sequestosome 1 | 0.0190903 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0190339 |
| TPR | translocated promoter region, nuclear basket protein | 0.0189504 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0189407 |
| GOLGB1 | golgin B1 | 0.0188763 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0187475 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0185689 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.018555 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0185123 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0185086 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0183438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.131837 |
| FLNB | filamin B, beta | -0.131193 |
| NPSR1 | neuropeptide S receptor 1 | -0.13044 |
| TMSB10 | thymosin beta 10 | -0.129625 |
| EZR | ezrin | -0.117399 |
| ANXA2 | annexin A2 | -0.110613 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.103069 |
| PTMA | prothymosin, alpha | -0.100322 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.096141 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0929058 |
| KRT18 | keratin 18, type I | -0.0927599 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0905471 |
| TPM4 | tropomyosin 4 | -0.0821738 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0814271 |
| ITGA6 | integrin, alpha 6 | -0.0783605 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0760517 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0685049 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0659627 |
| KRT8 | keratin 8, type II | -0.0645915 |
| LMO7 | LIM domain 7 | -0.0621171 |
| LAMA4 | laminin, alpha 4 | -0.0616686 |
| S100A6 | S100 calcium binding protein A6 | -0.0615791 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0612809 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0612192 |
| FAT1 | FAT atypical cadherin 1 | -0.0607032 |
| ACTN4 | actinin, alpha 4 | -0.0583438 |
| ONECUT3 | one cut homeobox 3 | -0.057942 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0578729 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0552998 |
| CALB1 | calbindin 1, 28kDa | -0.0548105 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0535694 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0517479 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0516327 |
| TNS4 | tensin 4 | -0.0512818 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0508302 |
| ACTG1 | actin gamma 1 | -0.0498229 |
| RNF217 | ring finger protein 217 | -0.0494936 |
| NDRG1 | N-myc downstream regulated 1 | -0.04924 |
| EMP1 | epithelial membrane protein 1 | -0.0490955 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0489711 |
| KRT19 | keratin 19, type I | -0.0473178 |
| S100A10 | S100 calcium binding protein A10 | -0.0470038 |
| POTEF | POTE ankyrin domain family, member F | -0.0466698 |
| FERMT1 | fermitin family member 1 | -0.0451734 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0451029 |
| MT2A | metallothionein 2A | -0.0450086 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0445072 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0443318 |
| ITGB4 | integrin, beta 4 | -0.0442053 |
| MUC17 | mucin 17, cell surface associated | -0.0427271 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.042555 |
| EGFR | epidermal growth factor receptor | -0.0419219 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0417574 |
| PRSS3 | protease, serine, 3 | -0.0413661 |
| LAMC2 | laminin, gamma 2 | -0.0411572 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.040968 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0408451 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0399976 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0390653 |
| CDCP1 | CUB domain containing protein 1 | -0.0388643 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0386455 |
| EHBP1 | EH domain binding protein 1 | -0.03864 |
| FOSL1 | FOS-like antigen 1 | -0.0383578 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0381337 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0380601 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0372316 |
| SVIL | supervillin | -0.0359696 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.035005 |
| SH3D19 | SH3 domain containing 19 | -0.0349412 |
| LMNA | lamin A/C | -0.0348831 |
| HMGA1 | high mobility group AT-hook 1 | -0.0348045 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0345124 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0344966 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.034165 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0338017 |
| PGK1 | phosphoglycerate kinase 1 | -0.0337967 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0332625 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0328592 |
| KLK10 | kallikrein-related peptidase 10 | -0.0328267 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0326936 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0323709 |
| AHNAK | AHNAK nucleoprotein | -0.0315385 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0310723 |
| RPS19 | ribosomal protein S19 | -0.030949 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0307276 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0302517 |
| DSPP | dentin sialophosphoprotein | -0.0299321 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0291455 |
| DIAPH1 | diaphanous-related formin 1 | -0.029104 |
| ANXA1 | annexin A1 | -0.0290646 |
| PERP | PERP, TP53 apoptosis effector | -0.029047 |
| PKM | pyruvate kinase, muscle | -0.0287839 |
| RCOR1 | REST corepressor 1 | -0.0283608 |
| TFF1 | trefoil factor 1 | -0.0283005 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0282858 |
| RPS6 | ribosomal protein S6 | -0.028182 |
| H1-0 | H1.0 linker histone | -0.0277762 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0274799 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.027376 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0273508 |
