| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Paclitaxel_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.081969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0787243 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0773857 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0759324 |
| PM20D1 | peptidase M20 domain containing 1 | 0.073114 |
| SPAG9 | sperm associated antigen 9 | 0.0727855 |
| TOP1 | topoisomerase (DNA) I | 0.0710256 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0622761 |
| USP34 | ubiquitin specific peptidase 34 | 0.0582345 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0574055 |
| MCL1 | myeloid cell leukemia 1 | 0.0565836 |
| PCBP2 | poly(rC) binding protein 2 | 0.0544714 |
| MKI67 | marker of proliferation Ki-67 | 0.0534231 |
| BRD2 | bromodomain containing 2 | 0.0526721 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0524791 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0508799 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0499003 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0488202 |
| VMP1 | vacuole membrane protein 1 | 0.0486401 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0483175 |
| HYOU1 | hypoxia up-regulated 1 | 0.0466496 |
| CANX | calnexin | 0.0464931 |
| SLTM | SAFB-like, transcription modulator | 0.0459657 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0432713 |
| NPTN | neuroplastin | 0.0431914 |
| TMEM165 | transmembrane protein 165 | 0.0430555 |
| FAT1 | FAT atypical cadherin 1 | 0.0418636 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0412677 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0402324 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0400374 |
| CCNL1 | cyclin L1 | 0.0392877 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0391926 |
| GOLGA4 | golgin A4 | 0.0385104 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0382086 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.037781 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0375525 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0366468 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0366391 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0366347 |
| PKM | pyruvate kinase, muscle | 0.0356253 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0348746 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0346209 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0346023 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0343478 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0338677 |
| FNIP1 | folliculin interacting protein 1 | 0.0338456 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0338108 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0327419 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0321829 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0319486 |
| HSPA8 | heat shock 70kDa protein 8 | 0.031866 |
| CPE | carboxypeptidase E | 0.0318303 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0318102 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0317833 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0316705 |
| TJP1 | tight junction protein 1 | 0.031663 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0309731 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0308673 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0305112 |
| TXNRD1 | thioredoxin reductase 1 | 0.0303434 |
| TUBA1C | tubulin, alpha 1c | 0.0301235 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0300168 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0300068 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0299603 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.029626 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0288953 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0288039 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0287944 |
| YTHDC1 | YTH domain containing 1 | 0.0287339 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0286608 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.028635 |
| PAPOLA | poly(A) polymerase alpha | 0.0285218 |
| RUNX1 | runt-related transcription factor 1 | 0.0285167 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0283461 |
| NGLY1 | N-glycanase 1 | 0.02818 |
| RBM39 | RNA binding motif protein 39 | 0.0279465 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0278536 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0273085 |
| RTN4 | reticulon 4 | 0.0272294 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0270539 |
| ANXA5 | annexin A5 | 0.0270083 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0269744 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0269286 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0268358 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0268243 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0268142 |
| COPA | coatomer protein complex, subunit alpha | 0.0263694 |
| RNF145 | ring finger protein 145 | 0.0261596 |
| EXOC6B | exocyst complex component 6B | 0.0260806 |
| CD163L1 | CD163 molecule-like 1 | 0.0258515 |
| POTEF | POTE ankyrin domain family, member F | 0.025839 |
| SRP54 | signal recognition particle 54kDa | 0.0257441 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0257405 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0255465 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0253855 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0252766 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0249486 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0248768 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0248294 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0247713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.17089 |
| LMO7 | LIM domain 7 | -0.131468 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.131212 |
| EGFR | epidermal growth factor receptor | -0.107797 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.09062 |
| AHNAK | AHNAK nucleoprotein | -0.0866109 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0801616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0747846 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.07019 |
| LAMC2 | laminin, gamma 2 | -0.06835 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0668904 |
| S100A10 | S100 calcium binding protein A10 | -0.0656693 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0640211 |
| H1-0 | H1.0 linker histone | -0.0607798 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0606755 |
| MYOF | myoferlin | -0.0587175 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0584808 |
| GRAMD1B | GRAM domain containing 1B | -0.0557616 |
| EFNA5 | ephrin-A5 | -0.0549145 |
| MYO1E | myosin IE | -0.0532631 |
| TMSB10 | thymosin beta 10 | -0.0514466 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0504635 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0450273 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0443459 |
| CP | ceruloplasmin (ferroxidase) | -0.0442321 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0442234 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0402733 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.040232 |
| OSMR | oncostatin M receptor | -0.0388862 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.038791 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0380459 |
| LDHA | lactate dehydrogenase A | -0.0358502 |
| RNF213 | ring finger protein 213 | -0.0355947 |
| MYO1D | myosin ID | -0.0355067 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0347287 |
| DSG2 | desmoglein 2 | -0.0345554 |
| GM2A | GM2 ganglioside activator | -0.0342912 |
| KRT18 | keratin 18, type I | -0.0338398 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0338029 |
| DSPP | dentin sialophosphoprotein | -0.0333296 |
| SCEL | sciellin | -0.0321666 |
| ANXA2 | annexin A2 | -0.031649 |
| LAMB3 | laminin, beta 3 | -0.0312971 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.030288 |
| ACTG1 | actin gamma 1 | -0.0302711 |
| INTS6 | integrator complex subunit 6 | -0.0299048 |
| MCU | mitochondrial calcium uniporter | -0.0298428 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0290939 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0287246 |
| FLNB | filamin B, beta | -0.028724 |
| FOXP1 | forkhead box P1 | -0.0285358 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0278741 |
| TNS3 | tensin 3 | -0.0277155 |
| USP53 | ubiquitin specific peptidase 53 | -0.0275982 |
| RPL34 | ribosomal protein L34 | -0.0275039 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0274528 |
| RPS24 | ribosomal protein S24 | -0.0274447 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0265017 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0264149 |
| CUX1 | cut-like homeobox 1 | -0.0261374 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0258982 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0243279 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0241769 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0240992 |
| KRT7 | keratin 7, type II | -0.0239145 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.023645 |
| PATJ | PATJ crumbs cell polarity complex component | -0.023276 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0230091 |
| CMIP | c-Maf inducing protein | -0.0227913 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.02271 |
| ANXA1 | annexin A1 | -0.0225037 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0224707 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0219781 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0215575 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0214094 |
| FAM107B | family with sequence similarity 107, member B | -0.0212631 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0212123 |
| HLA-B | major histocompatibility complex, class I, B | -0.0207512 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0206609 |
| APP | amyloid beta (A4) precursor protein | -0.0204138 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0202738 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0200665 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0199742 |
| S100A6 | S100 calcium binding protein A6 | -0.0198507 |
| GNAS | GNAS complex locus | -0.019782 |
| AGR2 | anterior gradient 2 | -0.0197633 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.019732 |
| SMAD3 | SMAD family member 3 | -0.0196844 |
| PYGL | phosphorylase, glycogen, liver | -0.019546 |
| SBF2 | SET binding factor 2 | -0.0195351 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0195213 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0194666 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.0192476 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0189581 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0186968 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0181857 |
| EHBP1 | EH domain binding protein 1 | -0.0180252 |
| TRIM56 | tripartite motif containing 56 | -0.0178722 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0176285 |
| ITGA6 | integrin, alpha 6 | -0.0170223 |
