| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.117088 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0694397 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0665268 |
| KYNU | kynureninase | 0.0614618 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0549999 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0461186 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0440415 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0437863 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0400535 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0400304 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0362336 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0335799 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0326789 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0307279 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0302912 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0302051 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0281579 |
| STK38L | serine/threonine kinase 38 like | 0.0280326 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0276195 |
| OSMR | oncostatin M receptor | 0.0276164 |
| MX1 | MX dynamin-like GTPase 1 | 0.0274971 |
| AHR | aryl hydrocarbon receptor | 0.0266643 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0263082 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0246624 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0245795 |
| HDAC9 | histone deacetylase 9 | 0.0243192 |
| CD44 | CD44 molecule (Indian blood group) | 0.0242336 |
| VMP1 | vacuole membrane protein 1 | 0.0238042 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0234404 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0233668 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0233414 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0229776 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0227386 |
| FRMD4A | FERM domain containing 4A | 0.0227379 |
| KSR1 | kinase suppressor of ras 1 | 0.0222698 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0220629 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0215854 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0215792 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0215335 |
| PCBP2 | poly(rC) binding protein 2 | 0.0214075 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0208374 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0208235 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0206284 |
| TGM2 | transglutaminase 2 | 0.0204858 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0202636 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0191359 |
| PLSCR1 | phospholipid scramblase 1 | 0.0190084 |
| TBK1 | TANK-binding kinase 1 | 0.0189846 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0188718 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0187099 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0186225 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0185968 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0182958 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0182129 |
| METTL15 | methyltransferase like 15 | 0.0180214 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0179829 |
| NAV2 | neuron navigator 2 | 0.0177517 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0176282 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0174305 |
| ADD3 | adducin 3 (gamma) | 0.0173484 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0172408 |
| OPTN | optineurin | 0.0171398 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0171005 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0170736 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0168479 |
| SMAD3 | SMAD family member 3 | 0.0168428 |
| IL1R1 | interleukin 1 receptor, type I | 0.0167515 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0166658 |
| LRRC49 | leucine rich repeat containing 49 | 0.0165717 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0162661 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0162013 |
| KIAA1217 | KIAA1217 | 0.016185 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0160151 |
| CDCP1 | CUB domain containing protein 1 | 0.0159059 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0157516 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0155743 |
| IL6ST | interleukin 6 signal transducer | 0.0154234 |
| RNF24 | ring finger protein 24 | 0.0153311 |
| FHIT | fragile histidine triad | 0.0151842 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.015182 |
| WWOX | WW domain containing oxidoreductase | 0.0151554 |
| PRELID2 | PRELI domain containing 2 | 0.015082 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0150205 |
| RPL3 | ribosomal protein L3 | 0.0149093 |
| RUNX2 | runt-related transcription factor 2 | 0.0148465 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0147159 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0146718 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0146465 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0146425 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0145462 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0144619 |
| RARB | retinoic acid receptor, beta | 0.0144322 |
| RAD51B | RAD51 paralog B | 0.0143938 |
| SMYD3 | SET and MYND domain containing 3 | 0.0143903 |
| FAM3C | family with sequence similarity 3, member C | 0.0143776 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0143516 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0142619 |
| MSN | moesin | 0.0142108 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0140878 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0139077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.160925 |
| TMSB10 | thymosin beta 10 | -0.153882 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.149815 |
| CDH13 | cadherin 13 | -0.147364 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.138226 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134965 |
| HMGA2 | high mobility group AT-hook 2 | -0.106567 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102266 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0995644 |
| FTL | ferritin, light polypeptide | -0.0986863 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.084437 |
| MTSS1 | metastasis suppressor 1 | -0.0812153 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0810453 |
| PTMA | prothymosin, alpha | -0.0795887 |
| FN1 | fibronectin 1 | -0.0773393 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0735773 |
| STC1 | stanniocalcin 1 | -0.0681192 |
| RPLP1 | ribosomal protein, large, P1 | -0.0637121 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0634135 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0622987 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0617864 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0606767 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0587386 |
| NRG1 | neuregulin 1 | -0.0577401 |
| IER3 | immediate early response 3 | -0.0554111 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0536345 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0512208 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0479336 |
| S100A6 | S100 calcium binding protein A6 | -0.0475111 |
| RPS19 | ribosomal protein S19 | -0.0459272 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0458434 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0455957 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0451294 |
| GOLGA4 | golgin A4 | -0.0448304 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0441866 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0441325 |
| FBN1 | fibrillin 1 | -0.0428362 |
| COL7A1 | collagen, type VII, alpha 1 | -0.042555 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0425291 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0408635 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0406171 |
| RPL35A | ribosomal protein L35a | -0.0400443 |
| RPL34 | ribosomal protein L34 | -0.0392306 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.038866 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0385009 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0382429 |
| GNAS | GNAS complex locus | -0.0381948 |
| RPL32 | ribosomal protein L32 | -0.0381571 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0381245 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0378193 |
| AADAC | arylacetamide deacetylase | -0.0377252 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0375244 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0375022 |
| MEF2A | myocyte enhancer factor 2A | -0.0373553 |
| S100A10 | S100 calcium binding protein A10 | -0.0370488 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0370343 |
| RPS8 | ribosomal protein S8 | -0.0364366 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0364177 |
| MT2A | metallothionein 2A | -0.0363876 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0361395 |
| RIOK3 | RIO kinase 3 | -0.0358616 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0357947 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0357074 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0355909 |
| RBM39 | RNA binding motif protein 39 | -0.0354057 |
| RPS29 | ribosomal protein S29 | -0.0353508 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0351472 |
| RPL23 | ribosomal protein L23 | -0.0351019 |
| HDLBP | high density lipoprotein binding protein | -0.0350142 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0349361 |
| RPS21 | ribosomal protein S21 | -0.0348542 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0348139 |
| FAM20C | family with sequence similarity 20, member C | -0.0348048 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0344232 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0344055 |
| CALU | calumenin | -0.0343964 |
| USP34 | ubiquitin specific peptidase 34 | -0.0342512 |
| EGR1 | early growth response 1 | -0.0341998 |
| CDK14 | cyclin-dependent kinase 14 | -0.0334706 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0332719 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0325843 |
| TMSB4X | thymosin beta 4, X-linked | -0.0325707 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.032275 |
| TGFB1 | transforming growth factor, beta 1 | -0.031966 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0316259 |
| RAB7A | RAB7A, member RAS oncogene family | -0.031288 |
| FAM107B | family with sequence similarity 107, member B | -0.0311737 |
| RPS24 | ribosomal protein S24 | -0.0311148 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0307519 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0305051 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0302113 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300119 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0299664 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0298594 |
| TMEM263 | transmembrane protein 263 | -0.0296146 |
| DPYD | dihydropyrimidine dehydrogenase | -0.029524 |
| RPLP0 | ribosomal protein, large, P0 | -0.0289925 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.028893 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0287152 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0287124 |
