| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.05292 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0136648 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0108739 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0107211 |
| SPAG9 | sperm associated antigen 9 | 0.0101622 |
| NTN4 | netrin 4 | 0.00948501 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00921688 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00904768 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0085688 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00794042 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.00780698 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.00762135 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00751941 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00744432 |
| PHF3 | PHD finger protein 3 | 0.00728034 |
| KYNU | kynureninase | 0.00705109 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.00696301 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00693656 |
| FGA | fibrinogen alpha chain | 0.00682509 |
| MATR3 | matrin 3 | 0.00674178 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00672366 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00667969 |
| NEK7 | NIMA-related kinase 7 | 0.00665159 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0066 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.00658843 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0063648 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00632701 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00628411 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00586893 |
| RPL4 | ribosomal protein L4 | 0.00567801 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0056534 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0052834 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.00527198 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00525093 |
| TUBB | tubulin, beta class I | 0.0051873 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00504368 |
| RPL3 | ribosomal protein L3 | 0.00499502 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00489723 |
| AURKA | aurora kinase A | 0.00472402 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.00464901 |
| TXNDC16 | thioredoxin domain containing 16 | 0.00462591 |
| NCKAP1 | NCK-associated protein 1 | 0.00458488 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00452015 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00449324 |
| JAK1 | Janus kinase 1 | 0.00445672 |
| PAPOLA | poly(A) polymerase alpha | 0.00443502 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00439469 |
| FGG | fibrinogen gamma chain | 0.00430445 |
| RBM33 | RNA binding motif protein 33 | 0.004262 |
| ATF6 | activating transcription factor 6 | 0.00424443 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00421617 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.00415613 |
| SAFB | scaffold attachment factor B | 0.00411797 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00411677 |
| BRD2 | bromodomain containing 2 | 0.00409324 |
| NPTN | neuroplastin | 0.00406938 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00406828 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0040355 |
| KIAA1217 | KIAA1217 | 0.0040283 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0040214 |
| NUP153 | nucleoporin 153kDa | 0.00397894 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00396459 |
| PDE10A | phosphodiesterase 10A | 0.0039478 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0038933 |
| KIAA0319 | KIAA0319 | 0.003866 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.00385668 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00382357 |
| RPS2 | ribosomal protein S2 | 0.00381541 |
| OGA | O-GlcNAcase | 0.00378407 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.00373717 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.003718 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00362046 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00356861 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00355096 |
| CUL3 | cullin 3 | 0.00350025 |
| RNF145 | ring finger protein 145 | 0.00348632 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00348616 |
| ABI1 | abl-interactor 1 | 0.00347838 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00347367 |
| TUBA1A | tubulin, alpha 1a | 0.00346181 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0033786 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00336668 |
| MRTFA | myocardin related transcription factor A | 0.00334851 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00334137 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.00331459 |
| HBP1 | HMG-box transcription factor 1 | 0.00331002 |
| SMAD2 | SMAD family member 2 | 0.00330161 |
| ATOSA | atos homolog A | 0.00330013 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00329048 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00327936 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.00327282 |
| H2AC6 | H2A clustered histone 6 | 0.00327195 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.00326625 |
| SERINC1 | serine incorporator 1 | 0.00326619 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0032361 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00322887 |
| CREBRF | CREB3 regulatory factor | 0.00322756 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00322036 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0031806 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.00317547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.303555 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167763 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.122475 |
| VIM | vimentin | -0.118252 |
| TMSB10 | thymosin beta 10 | -0.115541 |
| GRAMD1B | GRAM domain containing 1B | -0.101627 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0736632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0687787 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0668259 |
| FTL | ferritin, light polypeptide | -0.0644378 |
| ACTG1 | actin gamma 1 | -0.0628316 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0609939 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0598139 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0585685 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0580069 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0572505 |
| CMIP | c-Maf inducing protein | -0.0543917 |
| IGF2 | insulin-like growth factor 2 | -0.051073 |
| MCL1 | myeloid cell leukemia 1 | -0.0466761 |
| IER3 | immediate early response 3 | -0.0411796 |
| S100A6 | S100 calcium binding protein A6 | -0.0395467 |
| STC1 | stanniocalcin 1 | -0.0379746 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0376364 |
| RPL23 | ribosomal protein L23 | -0.0371665 |
| PYGL | phosphorylase, glycogen, liver | -0.0356038 |
| RPL19 | ribosomal protein L19 | -0.0341823 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.03376 |
| PTMA | prothymosin, alpha | -0.0331438 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0323968 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0323366 |
| PKM | pyruvate kinase, muscle | -0.0312039 |
| FLNB | filamin B, beta | -0.0310374 |
| DOCK5 | dedicator of cytokinesis 5 | -0.030595 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.029848 |
| EGR1 | early growth response 1 | -0.0294472 |
| RPS8 | ribosomal protein S8 | -0.0293223 |
| RPLP1 | ribosomal protein, large, P1 | -0.0292086 |
| RPL35A | ribosomal protein L35a | -0.0290419 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0289233 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0286058 |
| LDHA | lactate dehydrogenase A | -0.0284064 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0275556 |
| PFN1 | profilin 1 | -0.0269182 |
| EGFR | epidermal growth factor receptor | -0.0268953 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.026592 |
| FAM107B | family with sequence similarity 107, member B | -0.0262457 |
| TPM4 | tropomyosin 4 | -0.0254023 |
| S100A10 | S100 calcium binding protein A10 | -0.0251538 |
| FMNL2 | formin-like 2 | -0.0250985 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0250336 |
| RPS6 | ribosomal protein S6 | -0.0248837 |
| NAV3 | neuron navigator 3 | -0.0247997 |
| RPS29 | ribosomal protein S29 | -0.0245652 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0245539 |
| RPL31 | ribosomal protein L31 | -0.0243793 |
| POTEF | POTE ankyrin domain family, member F | -0.0243351 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0241456 |
| RPS19 | ribosomal protein S19 | -0.0240695 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0238716 |
| RPL37A | ribosomal protein L37a | -0.0237969 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0235625 |
| ACTN1 | actinin, alpha 1 | -0.0234213 |
| NRG1 | neuregulin 1 | -0.0233467 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0229102 |
| RPS21 | ribosomal protein S21 | -0.0228574 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0228402 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0218649 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0218085 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.021638 |
| RPL36 | ribosomal protein L36 | -0.021461 |
| ASPH | aspartate beta-hydroxylase | -0.0212689 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0210354 |
| HMGA1 | high mobility group AT-hook 1 | -0.0200533 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0199526 |
| S100A11 | S100 calcium binding protein A11 | -0.0196138 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0195589 |
| RPS25 | ribosomal protein S25 | -0.0194873 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0193775 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0191747 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0188022 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0186135 |
| BICC1 | BicC family RNA binding protein 1 | -0.0185921 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0182873 |
| AK1 | adenylate kinase 1 | -0.0181479 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0180175 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0178948 |
| OSMR | oncostatin M receptor | -0.0177739 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0177561 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0177503 |
| TXNRD1 | thioredoxin reductase 1 | -0.0176824 |
| SVIL | supervillin | -0.0176544 |
| HLA-B | major histocompatibility complex, class I, B | -0.0175763 |
| PRDX1 | peroxiredoxin 1 | -0.0173988 |
| ERBIN | erbb2 interacting protein | -0.0171126 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0168734 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0168508 |
| GLIS3 | GLIS family zinc finger 3 | -0.0167824 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0167285 |
| RPS23 | ribosomal protein S23 | -0.016643 |
| RPS16 | ribosomal protein S16 | -0.0165807 |
