| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.112307 |
| PDE10A | phosphodiesterase 10A | 0.0975118 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0849244 |
| KYNU | kynureninase | 0.0750491 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0697124 |
| DST | dystonin | 0.0664303 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0634416 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0623309 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0582967 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0460024 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0455536 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0390868 |
| SMAD2 | SMAD family member 2 | 0.0388248 |
| FMNL2 | formin-like 2 | 0.038814 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0384145 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0371216 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0369379 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.03637 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0359189 |
| FNIP1 | folliculin interacting protein 1 | 0.0345135 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0345038 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0344961 |
| NTN4 | netrin 4 | 0.0334867 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332983 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0331467 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0313837 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.030533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.030466 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0298379 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.0289655 |
| PTEN | phosphatase and tensin homolog | 0.0285338 |
| XYLT1 | xylosyltransferase I | 0.0285196 |
| DNER | delta/notch-like EGF repeat containing | 0.0283618 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0276992 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0269747 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0266163 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0264065 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0255686 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0252767 |
| PRELID2 | PRELI domain containing 2 | 0.0243054 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0241618 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0232207 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0223898 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0221615 |
| LAMA1 | laminin, alpha 1 | 0.0219603 |
| AUTS2 | autism susceptibility candidate 2 | 0.0217011 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0213638 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0204 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0197694 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0194724 |
| TBXT | T-box transcription factor T | 0.019445 |
| INTS6 | integrator complex subunit 6 | 0.019443 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0192631 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.01923 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0191229 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0189235 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0186862 |
| COPA | coatomer protein complex, subunit alpha | 0.0185592 |
| OXSR1 | oxidative stress responsive 1 | 0.0182555 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0181143 |
| ZNF644 | zinc finger protein 644 | 0.0174518 |
| RPL3 | ribosomal protein L3 | 0.0168187 |
| HDAC4 | histone deacetylase 4 | 0.0168089 |
| COL5A2 | collagen, type V, alpha 2 | 0.0167621 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0167166 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0164334 |
| SVIL | supervillin | 0.016336 |
| CDH13 | cadherin 13 | 0.0161633 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0158848 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0157998 |
| GLCE | glucuronic acid epimerase | 0.0157988 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.015727 |
| RAD51B | RAD51 paralog B | 0.0154987 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0154333 |
| TMEM178B | transmembrane protein 178B | 0.0154018 |
| CHSY3 | chondroitin sulfate synthase 3 | 0.01527 |
| TENM2 | teneurin transmembrane protein 2 | 0.0148862 |
| TUBB | tubulin, beta class I | 0.0147781 |
| FAT1 | FAT atypical cadherin 1 | 0.0145782 |
| ACVR1 | activin A receptor, type I | 0.0143837 |
| ATP9B | ATPase, class II, type 9B | 0.0143814 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.014339 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0142994 |
| EXOC4 | exocyst complex component 4 | 0.0142955 |
| VMP1 | vacuole membrane protein 1 | 0.0141967 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0138754 |
| EXOC6B | exocyst complex component 6B | 0.0137517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0136313 |
| PRR5L | proline rich 5 like | 0.0135129 |
| NRG1 | neuregulin 1 | 0.0134097 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.0134009 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0133603 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0132082 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0131704 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.013117 |
| CDK13 | cyclin-dependent kinase 13 | 0.013117 |
| KIAA0825 | KIAA0825 | 0.0131062 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0130049 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0129725 |
| RCOR1 | REST corepressor 1 | 0.012959 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.246945 |
| VIM | vimentin | -0.161504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.157222 |
| TMSB10 | thymosin beta 10 | -0.118474 |
| PTMA | prothymosin, alpha | -0.105023 |
| ASPH | aspartate beta-hydroxylase | -0.0925563 |
| RPS6 | ribosomal protein S6 | -0.0906429 |
| RPLP1 | ribosomal protein, large, P1 | -0.0864544 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0850085 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0832027 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0819824 |
| EFNA5 | ephrin-A5 | -0.0807609 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0802749 |
| NRCAM | neuronal cell adhesion molecule | -0.0792001 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0728896 |
| RPS8 | ribosomal protein S8 | -0.0721872 |
| FTL | ferritin, light polypeptide | -0.0711324 |
| RPS24 | ribosomal protein S24 | -0.0649133 |
| FN1 | fibronectin 1 | -0.0636972 |
| S100A6 | S100 calcium binding protein A6 | -0.062433 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0623408 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0564877 |
| RPL23 | ribosomal protein L23 | -0.0564369 |
| RPL12 | ribosomal protein L12 | -0.0560662 |
| S100A10 | S100 calcium binding protein A10 | -0.0555111 |
| STC1 | stanniocalcin 1 | -0.055439 |
| RPS19 | ribosomal protein S19 | -0.0539394 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0538329 |
| RPL19 | ribosomal protein L19 | -0.0537603 |
| RPL35A | ribosomal protein L35a | -0.0530458 |
| RPL26 | ribosomal protein L26 | -0.0530345 |
| PGK1 | phosphoglycerate kinase 1 | -0.0529693 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0511287 |
| RPLP0 | ribosomal protein, large, P0 | -0.0509872 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0505301 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0503146 |
| RPL34 | ribosomal protein L34 | -0.0494454 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.049078 |
| RPL31 | ribosomal protein L31 | -0.0490692 |
| RPL37A | ribosomal protein L37a | -0.0469716 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0465258 |
| SRGN | serglycin | -0.0459878 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0452931 |
| GNAS | GNAS complex locus | -0.0431997 |
| RACK1 | receptor for activated C kinase 1 | -0.0429798 |
| ENO1 | enolase 1, (alpha) | -0.0423916 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0418426 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0411912 |
| RPS14 | ribosomal protein S14 | -0.0405926 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0403934 |
| PCBP3 | poly(rC) binding protein 3 | -0.0400256 |
| RPS23 | ribosomal protein S23 | -0.0399615 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0396318 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0391694 |
| LMNA | lamin A/C | -0.0391117 |
| RPS27A | ribosomal protein S27a | -0.0389454 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0388114 |
| RPS12 | ribosomal protein S12 | -0.0387115 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0386785 |
| LDHA | lactate dehydrogenase A | -0.0384744 |
| B2M | beta-2-microglobulin | -0.0381205 |
| INHBA | inhibin, beta A | -0.037973 |
| RPL9 | ribosomal protein L9 | -0.0377457 |
| MT2A | metallothionein 2A | -0.0374511 |
| RPS3 | ribosomal protein S3 | -0.0374466 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.037251 |
| RPL32 | ribosomal protein L32 | -0.0371737 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0366578 |
| HLA-B | major histocompatibility complex, class I, B | -0.0365323 |
| GRAMD1B | GRAM domain containing 1B | -0.0362367 |
| RPL7A | ribosomal protein L7a | -0.0347427 |
| RPLP2 | ribosomal protein, large, P2 | -0.0342019 |
| RPS4X | ribosomal protein S4, X-linked | -0.0341389 |
| RPL36A | ribosomal protein L36a | -0.0341304 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.033751 |
| RPS21 | ribosomal protein S21 | -0.0336436 |
| RPS27 | ribosomal protein S27 | -0.0324793 |
| CANX | calnexin | -0.0322153 |
| RPL36 | ribosomal protein L36 | -0.0314127 |
| RPL37 | ribosomal protein L37 | -0.0311957 |
| RPS29 | ribosomal protein S29 | -0.031025 |
| RPL11 | ribosomal protein L11 | -0.0305171 |
| RPS25 | ribosomal protein S25 | -0.0300403 |
| RPL18 | ribosomal protein L18 | -0.0299912 |
| TMSB4X | thymosin beta 4, X-linked | -0.0296339 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.029569 |
| RPS16 | ribosomal protein S16 | -0.0295574 |
| RPL35 | ribosomal protein L35 | -0.0289828 |
| LAMB1 | laminin, beta 1 | -0.028697 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0286677 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0286605 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.028512 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0280014 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0279513 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0276365 |
| RTN1 | reticulon 1 | -0.0274596 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0272085 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.02717 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.027098 |
| RPS13 | ribosomal protein S13 | -0.026731 |
