| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.150703 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.115844 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.108958 |
| WAC | WW domain containing adaptor with coiled-coil | 0.102559 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.101009 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0968047 |
| FAT1 | FAT atypical cadherin 1 | 0.0960109 |
| PARD3 | par-3 family cell polarity regulator | 0.0959013 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0930095 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0848895 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0778807 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0733811 |
| ENO1 | enolase 1, (alpha) | 0.0731338 |
| KIF5B | kinesin family member 5B | 0.0727504 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0718365 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.071639 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0703681 |
| BPTF | bromodomain PHD finger transcription factor | 0.0679208 |
| FOXO3 | forkhead box O3 | 0.0673185 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0642392 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0636434 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0628593 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0625963 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0624232 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0621947 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0621536 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0608392 |
| EZR | ezrin | 0.0605264 |
| DTNA | dystrobrevin, alpha | 0.0594169 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0569039 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0563242 |
| PMM2 | phosphomannomutase 2 | 0.055866 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0547697 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0545301 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0541973 |
| ASPH | aspartate beta-hydroxylase | 0.0533718 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0510043 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0508114 |
| ERBIN | erbb2 interacting protein | 0.0489821 |
| GNAS | GNAS complex locus | 0.0482863 |
| RPL23 | ribosomal protein L23 | 0.0481935 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0477403 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0470739 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.046612 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0457802 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0449701 |
| PDE8A | phosphodiesterase 8A | 0.0449258 |
| CANX | calnexin | 0.0442114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0441148 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0437093 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.043638 |
| SPAG9 | sperm associated antigen 9 | 0.0426972 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0425567 |
| HDLBP | high density lipoprotein binding protein | 0.041482 |
| RORA | RAR-related orphan receptor A | 0.0402889 |
| LMO7 | LIM domain 7 | 0.0399885 |
| ATXN1 | ataxin 1 | 0.0395624 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0387899 |
| YAP1 | Yes-associated protein 1 | 0.0387045 |
| OGA | O-GlcNAcase | 0.038409 |
| FER | fer (fps/fes related) tyrosine kinase | 0.037506 |
| SQSTM1 | sequestosome 1 | 0.0369807 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0357322 |
| GPC6 | glypican 6 | 0.0352775 |
| MYO6 | myosin VI | 0.0351157 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0349142 |
| RAI14 | retinoic acid induced 14 | 0.0341589 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0336616 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0334609 |
| GOLGA4 | golgin A4 | 0.0323922 |
| SCFD1 | sec1 family domain containing 1 | 0.0322581 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0322319 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0319298 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0308581 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0291825 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0282235 |
| PTK2 | protein tyrosine kinase 2 | 0.0282046 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0281485 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0277681 |
| PRKCA | protein kinase C, alpha | 0.0276324 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0274006 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0268727 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.026572 |
| ACTG1 | actin gamma 1 | 0.0258793 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0257785 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.02528 |
| SBF2 | SET binding factor 2 | 0.0251005 |
| INHBA | inhibin, beta A | 0.0250794 |
| HDAC9 | histone deacetylase 9 | 0.0232002 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0231798 |
| EFNA5 | ephrin-A5 | 0.0231412 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0216788 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0213283 |
| DST | dystonin | 0.0209387 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0201386 |
| RTN4 | reticulon 4 | 0.0191035 |
| RUNX1 | runt-related transcription factor 1 | 0.0180514 |
| ANXA2 | annexin A2 | 0.0178858 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0173384 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0172809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.247928 |
| EGFR | epidermal growth factor receptor | -0.199519 |
| VIM | vimentin | -0.194807 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.192466 |
| TMSB10 | thymosin beta 10 | -0.157745 |
| PKM | pyruvate kinase, muscle | -0.126487 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.103449 |
| NAV1 | neuron navigator 1 | -0.0898555 |
| B2M | beta-2-microglobulin | -0.0889211 |
| RPS8 | ribosomal protein S8 | -0.0885752 |
| HMGA2 | high mobility group AT-hook 2 | -0.0828357 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0825284 |
| CCNI | cyclin I | -0.0815485 |
| FN1 | fibronectin 1 | -0.0751819 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0730126 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0717 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0704301 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0701769 |
| S100A9 | S100 calcium binding protein A9 | -0.0701136 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0697922 |
| NF1 | neurofibromin 1 | -0.0679162 |
| RPL11 | ribosomal protein L11 | -0.0677737 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0671971 |
| FLNB | filamin B, beta | -0.0671796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0667143 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0652658 |
| POTEF | POTE ankyrin domain family, member F | -0.0586882 |
| PTMA | prothymosin, alpha | -0.0574791 |
| TXNRD1 | thioredoxin reductase 1 | -0.0572507 |
| CDCP1 | CUB domain containing protein 1 | -0.0541354 |
| HLA-B | major histocompatibility complex, class I, B | -0.0533931 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0529877 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0517241 |
| S100A6 | S100 calcium binding protein A6 | -0.0505998 |
| LOXL2 | lysyl oxidase-like 2 | -0.0503573 |
| MYO1E | myosin IE | -0.0500227 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0482437 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0466572 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0459288 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0445179 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0441464 |
| MAP1B | microtubule-associated protein 1B | -0.0440008 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0424983 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.042412 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0420365 |
| TAOK3 | TAO kinase 3 | -0.0414005 |
| VEGFA | vascular endothelial growth factor A | -0.0409757 |
| VCL | vinculin | -0.0407773 |
| OSMR | oncostatin M receptor | -0.0404537 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0397708 |
| UBC | ubiquitin C | -0.0397435 |
| FMNL2 | formin-like 2 | -0.0396982 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0395187 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0392976 |
| SNX14 | sorting nexin 14 | -0.039187 |
| LMNA | lamin A/C | -0.0387438 |
| RPLP1 | ribosomal protein, large, P1 | -0.0381258 |
| STC1 | stanniocalcin 1 | -0.0369614 |
| AHNAK | AHNAK nucleoprotein | -0.0364042 |
| RPL31 | ribosomal protein L31 | -0.0355544 |
| ANO6 | anoctamin 6 | -0.0351477 |
| MAP4 | microtubule-associated protein 4 | -0.0351239 |
| PRELID2 | PRELI domain containing 2 | -0.0349639 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0349288 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0344413 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0340024 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.033945 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0337362 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0336201 |
| GANAB | glucosidase, alpha; neutral AB | -0.0326191 |
| RPL32 | ribosomal protein L32 | -0.0326015 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0319322 |
| ARRDC3 | arrestin domain containing 3 | -0.0316904 |
| RACK1 | receptor for activated C kinase 1 | -0.0312507 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0296568 |
| RNF149 | ring finger protein 149 | -0.0294804 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0291582 |
| SMYD3 | SET and MYND domain containing 3 | -0.0291225 |
| PGK1 | phosphoglycerate kinase 1 | -0.0288349 |
| LDHA | lactate dehydrogenase A | -0.0285312 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0275811 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0275756 |
| YBX3 | Y box binding protein 3 | -0.0274639 |
| RPL35A | ribosomal protein L35a | -0.0272438 |
| RPL13A | ribosomal protein L13a | -0.0269039 |
| RNF213 | ring finger protein 213 | -0.0258882 |
| CD44 | CD44 molecule (Indian blood group) | -0.0257724 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0256166 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0248323 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0241239 |
| RPS12 | ribosomal protein S12 | -0.0230484 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0228532 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0221831 |
| PRSS23 | protease, serine, 23 | -0.0218272 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0205828 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0199655 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0199136 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0199071 |
| RPS13 | ribosomal protein S13 | -0.0194735 |
| RPL26 | ribosomal protein L26 | -0.0193877 |
