| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Paclitaxel_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.174685 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0951463 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0646716 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0641157 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0599979 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0576522 |
| ANK2 | ankyrin 2, neuronal | 0.0551097 |
| CENPF | centromere protein F, 350/400kDa | 0.0534835 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0533198 |
| TENM2 | teneurin transmembrane protein 2 | 0.0499761 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0495806 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0494492 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0465774 |
| STAG2 | stromal antigen 2 | 0.0449577 |
| RAD51B | RAD51 paralog B | 0.0444509 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0438575 |
| UBAP2 | ubiquitin associated protein 2 | 0.0436888 |
| DST | dystonin | 0.0433542 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0414227 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0412034 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0407077 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0396803 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.039643 |
| CTBP2 | C-terminal binding protein 2 | 0.0392101 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0392074 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0373186 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0368715 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0364136 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0360464 |
| GPHN | gephyrin | 0.0359883 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0357166 |
| TENM3 | teneurin transmembrane protein 3 | 0.0355698 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0347526 |
| MCL1 | myeloid cell leukemia 1 | 0.0343711 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0337532 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.033717 |
| NEBL | nebulette | 0.0336496 |
| JMJD1C | jumonji domain containing 1C | 0.0334177 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0331309 |
| CDK13 | cyclin-dependent kinase 13 | 0.0327576 |
| ATXN2 | ataxin 2 | 0.032316 |
| APP | amyloid beta (A4) precursor protein | 0.0322073 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0320624 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.032047 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0318871 |
| SYT1 | synaptotagmin I | 0.0318756 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.031873 |
| NXN | nucleoredoxin | 0.0318133 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0318074 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.031414 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0311821 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0310013 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0308762 |
| INTS6 | integrator complex subunit 6 | 0.030732 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0305212 |
| GPC4 | glypican 4 | 0.0300977 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0299092 |
| PRRC2C | proline-rich coiled-coil 2C | 0.029412 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0293535 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0289352 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0288349 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0287722 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0284736 |
| NRG1 | neuregulin 1 | 0.0284416 |
| TCF12 | transcription factor 12 | 0.0283425 |
| MKI67 | marker of proliferation Ki-67 | 0.0282227 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0281827 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0280327 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 0.0278306 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0275923 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0274614 |
| TEX11 | testis expressed 11 | 0.0273308 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.027251 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0269418 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0267881 |
| TUBA1B | tubulin, alpha 1b | 0.0267852 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0267613 |
| MT2A | metallothionein 2A | 0.0267081 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0265842 |
| CEP350 | centrosomal protein 350kDa | 0.0263439 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0262151 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0260053 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0259376 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0257405 |
| MED13 | mediator complex subunit 13 | 0.0256631 |
| HELZ | helicase with zinc finger | 0.0256098 |
| EGFR | epidermal growth factor receptor | 0.0255024 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.025362 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0251739 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0251551 |
| USP25 | ubiquitin specific peptidase 25 | 0.0250137 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0249502 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0248985 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0248895 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0246957 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.024691 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243291 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.024268 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0241153 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0240713 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.203633 |
| COL5A2 | collagen, type V, alpha 2 | -0.155049 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.145354 |
| COL11A1 | collagen, type XI, alpha 1 | -0.109148 |
| VIM | vimentin | -0.0703712 |
| GPC3 | glypican 3 | -0.0624652 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0599181 |
| PCDH9 | protocadherin 9 | -0.0585437 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0583023 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0580074 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0515967 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.050958 |
| COL3A1 | collagen, type III, alpha 1 | -0.0478649 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.046535 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0461844 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0438015 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0432052 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0427783 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0418354 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0413475 |
| PEG10 | paternally expressed 10 | -0.0413103 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0412921 |
| COL1A2 | collagen, type I, alpha 2 | -0.0408877 |
| PFN1 | profilin 1 | -0.0398468 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0397829 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0392422 |
| CADM2 | cell adhesion molecule 2 | -0.0389961 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0362644 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0356936 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0350204 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0338077 |
| METAP2 | methionyl aminopeptidase 2 | -0.0332819 |
| PGK1 | phosphoglycerate kinase 1 | -0.0331485 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0328809 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0324037 |
| FOXG1 | forkhead box G1 | -0.0323601 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0321345 |
| PHIP | pleckstrin homology domain interacting protein | -0.0321238 |
| FIGN | fidgetin | -0.0317967 |
| ANXA1 | annexin A1 | -0.031458 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0309933 |
| MEIS2 | Meis homeobox 2 | -0.0309679 |
| TMSB4X | thymosin beta 4, X-linked | -0.0306802 |
| THBS1 | thrombospondin 1 | -0.0306503 |
| PROS1 | protein S (alpha) | -0.0304801 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.030422 |
| USP3 | ubiquitin specific peptidase 3 | -0.0299415 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0297491 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0293328 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0291864 |
| HMGA1 | high mobility group AT-hook 1 | -0.0287025 |
| RHOH | ras homolog family member H | -0.0283641 |
| NBEAL1 | neurobeachin-like 1 | -0.0282721 |
| CCN2 | cellular communication network factor 2 | -0.028012 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0278903 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0275827 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0274463 |
| RPS8 | ribosomal protein S8 | -0.0272098 |
| CALCR | calcitonin receptor | -0.027102 |
| B2M | beta-2-microglobulin | -0.0267481 |
| RTN4 | reticulon 4 | -0.0265633 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0263177 |
| MEF2C | myocyte enhancer factor 2C | -0.0261169 |
| LYPLA1 | lysophospholipase I | -0.026095 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0260037 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0259653 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0257599 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0257356 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0254896 |
| RFPL4B | ret finger protein-like 4B | -0.0253593 |
| FBXO11 | F-box protein 11 | -0.0248364 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0248255 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0243676 |
| ZNF292 | zinc finger protein 292 | -0.0242527 |
| CAPNS1 | calpain, small subunit 1 | -0.0241096 |
| TNPO3 | transportin 3 | -0.0240181 |
| MACROD2 | MACRO domain containing 2 | -0.0236967 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0227774 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0226983 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0226321 |
| GNAS | GNAS complex locus | -0.0223791 |
| RPL18 | ribosomal protein L18 | -0.022334 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0222689 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0222378 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.022128 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0219495 |
| SPAG9 | sperm associated antigen 9 | -0.0217712 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0217608 |
| CAVIN1 | caveolae associated protein 1 | -0.0215897 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0214926 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0213773 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0212299 |
| QKI | QKI, KH domain containing, RNA binding | -0.0211722 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0210974 |
| YBX1 | Y box binding protein 1 | -0.0209032 |
| ZFR | zinc finger RNA binding protein | -0.0208029 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0207745 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0207661 |
| LRRC4C | leucine rich repeat containing 4C | -0.0206748 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0205573 |
