| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Paclitaxel_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.121121 |
| HMGA2 | high mobility group AT-hook 2 | 0.105386 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0912282 |
| CDH13 | cadherin 13 | 0.0911055 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.085131 |
| HDAC9 | histone deacetylase 9 | 0.0847283 |
| NDRG1 | N-myc downstream regulated 1 | 0.0788099 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0687859 |
| DST | dystonin | 0.0683723 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0669169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0658535 |
| TUBB | tubulin, beta class I | 0.0633393 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0609906 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0606428 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0567723 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0552063 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.055058 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0548217 |
| CALR | calreticulin | 0.0547437 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0544255 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0539023 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.052529 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0510625 |
| NAV2 | neuron navigator 2 | 0.0498098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0481288 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0471778 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0469874 |
| FNIP1 | folliculin interacting protein 1 | 0.0467699 |
| ASPH | aspartate beta-hydroxylase | 0.0465397 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0452712 |
| BRD2 | bromodomain containing 2 | 0.0448134 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0446838 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0440132 |
| CANX | calnexin | 0.0434893 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0429394 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0420725 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0417098 |
| STC1 | stanniocalcin 1 | 0.0409756 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0402671 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.038996 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0389366 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0384015 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0374319 |
| INTS6 | integrator complex subunit 6 | 0.0365021 |
| TMEM132D | transmembrane protein 132D | 0.0357041 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0356396 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0352766 |
| RND3 | Rho family GTPase 3 | 0.0344513 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0332214 |
| HLA-A | major histocompatibility complex, class I, A | 0.0327532 |
| HLA-E | major histocompatibility complex, class I, E | 0.0325344 |
| DUSP10 | dual specificity phosphatase 10 | 0.0324345 |
| FMNL2 | formin-like 2 | 0.0322395 |
| SP100 | SP100 nuclear antigen | 0.0313245 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0312477 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0296613 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0296325 |
| PGM3 | phosphoglucomutase 3 | 0.0294042 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0293 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0290978 |
| ADM | adrenomedullin | 0.0280798 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0280109 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0279788 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0275622 |
| ATXN1 | ataxin 1 | 0.0274253 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0273284 |
| EXOC4 | exocyst complex component 4 | 0.0266071 |
| RPS12 | ribosomal protein S12 | 0.0262957 |
| PRELID2 | PRELI domain containing 2 | 0.0262192 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0261158 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0261124 |
| SQSTM1 | sequestosome 1 | 0.0260816 |
| SFTPA2 | surfactant protein A2 | 0.0258171 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257884 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0253889 |
| PHF3 | PHD finger protein 3 | 0.0252593 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0251825 |
| GPR39 | G protein-coupled receptor 39 | 0.0251511 |
| OPTN | optineurin | 0.0250444 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0246522 |
| MSN | moesin | 0.0243868 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.024336 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0243282 |
| EXOC6B | exocyst complex component 6B | 0.0238551 |
| GOLGB1 | golgin B1 | 0.0236923 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0236446 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0235978 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0233155 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0229242 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0229167 |
| TBC1D19 | TBC1 domain family, member 19 | 0.0228124 |
| PRKCE | protein kinase C, epsilon | 0.0227719 |
| MMP12 | matrix metallopeptidase 12 | 0.0227085 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0226673 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0224989 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0223071 |
| SMYD3 | SET and MYND domain containing 3 | 0.0223 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0222264 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0219957 |
| HLA-B | major histocompatibility complex, class I, B | 0.0217988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.133404 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111858 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.109217 |
| VIM | vimentin | -0.105762 |
| BICC1 | BicC family RNA binding protein 1 | -0.0847316 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0790962 |
| VCL | vinculin | -0.0745201 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0726964 |
| TMSB10 | thymosin beta 10 | -0.0721051 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0656091 |
| THBS1 | thrombospondin 1 | -0.062361 |
| EGR1 | early growth response 1 | -0.0528976 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0516568 |
| MYOF | myoferlin | -0.0491903 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0483997 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0461599 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0429848 |
| ANXA2 | annexin A2 | -0.0428994 |
| SBF2 | SET binding factor 2 | -0.0413105 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.040321 |
| SMAD3 | SMAD family member 3 | -0.0402811 |
| VCAN | versican | -0.0383138 |
| OSMR | oncostatin M receptor | -0.0373278 |
| FN1 | fibronectin 1 | -0.0370089 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0362818 |
| KLF6 | Kruppel-like factor 6 | -0.0338514 |
| RPL23 | ribosomal protein L23 | -0.0333025 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0316584 |
| RTN4 | reticulon 4 | -0.0315949 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0305713 |
| GNAS | GNAS complex locus | -0.0305495 |
| RPL32 | ribosomal protein L32 | -0.0293511 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0293125 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0290372 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0289674 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0288274 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0286851 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0284049 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0281194 |
| TNS3 | tensin 3 | -0.0276181 |
| PALLD | palladin, cytoskeletal associated protein | -0.0257638 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0251326 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0250923 |
| FTL | ferritin, light polypeptide | -0.0245649 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0245471 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0244203 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0240065 |
| UBC | ubiquitin C | -0.0239302 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0235446 |
| RPLP0 | ribosomal protein, large, P0 | -0.0233818 |
| RPS24 | ribosomal protein S24 | -0.0224747 |
| RUNX2 | runt-related transcription factor 2 | -0.0222886 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0222569 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0220423 |
| RPLP1 | ribosomal protein, large, P1 | -0.0212933 |
| YBX3 | Y box binding protein 3 | -0.0206502 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.020414 |
| ASTN2 | astrotactin 2 | -0.0203984 |
| TENM2 | teneurin transmembrane protein 2 | -0.0203206 |
| IER3 | immediate early response 3 | -0.0199447 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0195563 |
| TMSB4X | thymosin beta 4, X-linked | -0.0192657 |
| KRT19 | keratin 19, type I | -0.0189717 |
| CRY1 | cryptochrome circadian clock 1 | -0.0189429 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0189249 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.018773 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0187043 |
| CENPF | centromere protein F, 350/400kDa | -0.0185377 |
| LRRC7 | leucine rich repeat containing 7 | -0.0184717 |
| ZNF292 | zinc finger protein 292 | -0.0184654 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0184558 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0184057 |
| ANLN | anillin, actin binding protein | -0.0182105 |
| RPL19 | ribosomal protein L19 | -0.0180581 |
| IL6 | interleukin 6 | -0.017789 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0175573 |
| S100A9 | S100 calcium binding protein A9 | -0.0174863 |
| TNNC1 | troponin C type 1 (slow) | -0.0174551 |
| TMEM123 | transmembrane protein 123 | -0.0173356 |
| RNF24 | ring finger protein 24 | -0.0173299 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.017276 |
| AFDN | afadin, adherens junction formation factor | -0.017244 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0171846 |
| QKI | QKI, KH domain containing, RNA binding | -0.0170735 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0170696 |
| RPS4X | ribosomal protein S4, X-linked | -0.016962 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0169242 |
| LMNA | lamin A/C | -0.0169114 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0166771 |
| RPS19 | ribosomal protein S19 | -0.0164646 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0164161 |
| RPS21 | ribosomal protein S21 | -0.0164127 |
| EZR | ezrin | -0.0162255 |
| CTSD | cathepsin D | -0.0162186 |
| RASAL2 | RAS protein activator like 2 | -0.0160158 |
| NAV1 | neuron navigator 1 | -0.0156457 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0154569 |
| CADM1 | cell adhesion molecule 1 | -0.0154417 |
| RPL35 | ribosomal protein L35 | -0.0153612 |
| RPL12 | ribosomal protein L12 | -0.0152948 |
