| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Paclitaxel_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.148095 |
| FN1 | fibronectin 1 | 0.0824699 |
| KYNU | kynureninase | 0.0651481 |
| HIP1 | huntingtin interacting protein 1 | 0.0581953 |
| CDH13 | cadherin 13 | 0.0579661 |
| FNIP1 | folliculin interacting protein 1 | 0.0471742 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0451832 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0449998 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0390366 |
| VEGFC | vascular endothelial growth factor C | 0.0364363 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0361158 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0347526 |
| GOLGB1 | golgin B1 | 0.0345319 |
| NRXN3 | neurexin 3 | 0.034194 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0335201 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0334461 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0331969 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0327188 |
| SQSTM1 | sequestosome 1 | 0.0307365 |
| INTS6 | integrator complex subunit 6 | 0.0301587 |
| EFNA5 | ephrin-A5 | 0.029394 |
| HMGA2 | high mobility group AT-hook 2 | 0.0289257 |
| UBAP2 | ubiquitin associated protein 2 | 0.0288082 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0288041 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0286775 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0286152 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0282081 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0275611 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0274246 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0271901 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0269849 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0267494 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0263696 |
| VCL | vinculin | 0.0261227 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0259315 |
| MKI67 | marker of proliferation Ki-67 | 0.0258652 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0255429 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0253012 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0247152 |
| CLIC4 | chloride intracellular channel 4 | 0.0244778 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0241081 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.023883 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0237238 |
| RND3 | Rho family GTPase 3 | 0.0235306 |
| FTO | fat mass and obesity associated | 0.0232674 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0224017 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0221095 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0219711 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0218401 |
| RAD51B | RAD51 paralog B | 0.0217004 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0215937 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.0214696 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.021213 |
| CDK6 | cyclin-dependent kinase 6 | 0.0212022 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0209334 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0208486 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0207943 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0207555 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0205791 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0202589 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0200555 |
| TPM1 | tropomyosin 1 (alpha) | 0.0200405 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0200218 |
| CDK13 | cyclin-dependent kinase 13 | 0.01998 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0199787 |
| WWOX | WW domain containing oxidoreductase | 0.0199708 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0198125 |
| WLS | wntless Wnt ligand secretion mediator | 0.0197817 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0197222 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0196472 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0196075 |
| EXOC4 | exocyst complex component 4 | 0.0193129 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.019039 |
| DMXL1 | Dmx-like 1 | 0.0189183 |
| KRIT1 | KRIT1, ankyrin repeat containing | 0.0187797 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0187186 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0186775 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0184618 |
| AHR | aryl hydrocarbon receptor | 0.0184519 |
| OPTN | optineurin | 0.0184101 |
| COPA | coatomer protein complex, subunit alpha | 0.0183964 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0183666 |
| CCND1 | cyclin D1 | 0.0180718 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0180661 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0180635 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0180034 |
| ATM | ATM serine/threonine kinase | 0.0179549 |
| TPR | translocated promoter region, nuclear basket protein | 0.0178987 |
| PHF14 | PHD finger protein 14 | 0.0178459 |
| VMP1 | vacuole membrane protein 1 | 0.017776 |
| COG6 | component of oligomeric golgi complex 6 | 0.0176881 |
| UBE3C | ubiquitin protein ligase E3C | 0.0176639 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0175511 |
| RAB31 | RAB31, member RAS oncogene family | 0.0174558 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0174181 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0173423 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0173213 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0173003 |
| GSE1 | Gse1 coiled-coil protein | 0.0171016 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.016996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233827 |
| TMSB10 | thymosin beta 10 | -0.203912 |
| MT2A | metallothionein 2A | -0.140223 |
| VIM | vimentin | -0.131361 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110983 |
| COL1A2 | collagen, type I, alpha 2 | -0.0896374 |
| B2M | beta-2-microglobulin | -0.0741749 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0703303 |
| HLA-B | major histocompatibility complex, class I, B | -0.0683794 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0671662 |
| CALU | calumenin | -0.066298 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.063697 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0616711 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0598601 |
| UBC | ubiquitin C | -0.0597896 |
| FTL | ferritin, light polypeptide | -0.0570245 |
| MT1X | metallothionein 1X | -0.0522851 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0517231 |
| PTMA | prothymosin, alpha | -0.0513012 |
| LDHA | lactate dehydrogenase A | -0.0506868 |
| ATP13A3 | ATPase type 13A3 | -0.0452438 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.043944 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0431983 |
| LOX | lysyl oxidase | -0.043162 |
| S100A10 | S100 calcium binding protein A10 | -0.0414637 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0407041 |
| ZNF292 | zinc finger protein 292 | -0.0389822 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0386966 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0385968 |
| S100A9 | S100 calcium binding protein A9 | -0.0372313 |
| TXNIP | thioredoxin interacting protein | -0.0367111 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0360078 |
| FAM13A | family with sequence similarity 13, member A | -0.0358299 |
| LMNA | lamin A/C | -0.0346831 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0345155 |
| RPL34 | ribosomal protein L34 | -0.0344828 |
| CALD1 | caldesmon 1 | -0.0342335 |
| S100A6 | S100 calcium binding protein A6 | -0.0341302 |
| EGFR | epidermal growth factor receptor | -0.0336776 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0328315 |
| PGK1 | phosphoglycerate kinase 1 | -0.0324573 |
| NDRG1 | N-myc downstream regulated 1 | -0.0319794 |
| CADM1 | cell adhesion molecule 1 | -0.0318105 |
| WTAP | Wilms tumor 1 associated protein | -0.0309493 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0299153 |
| COL1A1 | collagen, type I, alpha 1 | -0.0295505 |
| HLA-C | major histocompatibility complex, class I, C | -0.0291316 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0291163 |
| CCNI | cyclin I | -0.0287753 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0286938 |
| GOLGA4 | golgin A4 | -0.0283974 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0278974 |
| ENO1 | enolase 1, (alpha) | -0.0278813 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0278258 |
| NOP58 | NOP58 ribonucleoprotein | -0.0274122 |
| EGR1 | early growth response 1 | -0.0271456 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0271424 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0271067 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0268197 |
| RPL36 | ribosomal protein L36 | -0.0264831 |
| RTN4 | reticulon 4 | -0.0262928 |
| ARRDC3 | arrestin domain containing 3 | -0.0262915 |
| ITM2B | integral membrane protein 2B | -0.0258713 |
| RPS24 | ribosomal protein S24 | -0.0253255 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0251877 |
| TMEM41B | transmembrane protein 41B | -0.0251687 |
| RPL23 | ribosomal protein L23 | -0.0247112 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.024475 |
| RACK1 | receptor for activated C kinase 1 | -0.0244413 |
| ANXA2 | annexin A2 | -0.0243276 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0241045 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0240852 |
| PHF21A | PHD finger protein 21A | -0.0238076 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0237613 |
| FAM162A | family with sequence similarity 162, member A | -0.0237205 |
| ZNF395 | zinc finger protein 395 | -0.0236189 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0233271 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0231159 |
| RPL28 | ribosomal protein L28 | -0.0230903 |
| GANAB | glucosidase, alpha; neutral AB | -0.023073 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0229992 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0229866 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0228226 |
| RRBP1 | ribosome binding protein 1 | -0.0227485 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0226652 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0225224 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0223235 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.021989 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0218998 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.021707 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0216588 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.021616 |
| GNAS | GNAS complex locus | -0.0215889 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0214278 |
| PFN1 | profilin 1 | -0.0212951 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0212764 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.021042 |
| SEPTIN7 | septin 7 | -0.0208661 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0206449 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0206256 |