| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Paclitaxel perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Paclitaxel_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CENPF | centromere protein F, 350/400kDa | 0.0692979 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0591121 |
| STC2 | stanniocalcin 2 | 0.0426948 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0417177 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0389745 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.03763 |
| DENND5B | DENN/MADD domain containing 5B | 0.0354842 |
| MKI67 | marker of proliferation Ki-67 | 0.0344553 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.031739 |
| ENAH | enabled homolog (Drosophila) | 0.0309339 |
| CANX | calnexin | 0.0306927 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0304973 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0302982 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0301819 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0298236 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295797 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0272801 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0255508 |
| OGA | O-GlcNAcase | 0.025487 |
| SQSTM1 | sequestosome 1 | 0.0254426 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0246314 |
| RPS12 | ribosomal protein S12 | 0.0244115 |
| TMEM178B | transmembrane protein 178B | 0.0243231 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.024295 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0237027 |
| XPO1 | exportin 1 | 0.0230724 |
| TPX2 | TPX2, microtubule-associated | 0.022985 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0225947 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0225665 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0225642 |
| NXN | nucleoredoxin | 0.0223574 |
| CREBRF | CREB3 regulatory factor | 0.0222562 |
| HSPA8 | heat shock 70kDa protein 8 | 0.022253 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0221659 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0218843 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.02182 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0217634 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0216669 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0216628 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0215522 |
| CEP350 | centrosomal protein 350kDa | 0.0214827 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0208172 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0206399 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0204994 |
| ATF6 | activating transcription factor 6 | 0.0204698 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0203609 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0203334 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0201522 |
| TUFT1 | tuftelin 1 | 0.0201014 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0200414 |
| IL6ST | interleukin 6 signal transducer | 0.0199738 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0196216 |
| PUM2 | pumilio RNA-binding family member 2 | 0.019528 |
| PAPOLA | poly(A) polymerase alpha | 0.0194024 |
| TXNRD1 | thioredoxin reductase 1 | 0.0192916 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0191082 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.019103 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0190775 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0190197 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0189116 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0188631 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0188612 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0187697 |
| RHEB | Ras homolog enriched in brain | 0.0186001 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0185481 |
| TUBB | tubulin, beta class I | 0.0185187 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0183657 |
| GPHN | gephyrin | 0.0181955 |
| PDS5A | PDS5 cohesin associated factor A | 0.0181553 |
| RPL26 | ribosomal protein L26 | 0.0180759 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0178537 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0177931 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0177209 |
| UBAP2 | ubiquitin associated protein 2 | 0.0176987 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0175587 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0175102 |
| RPS27A | ribosomal protein S27a | 0.0173365 |
| ANLN | anillin, actin binding protein | 0.017236 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0172193 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0169722 |
| RACK1 | receptor for activated C kinase 1 | 0.0169304 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0166935 |
| RPL37A | ribosomal protein L37a | 0.0165458 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0165091 |
| ENO1 | enolase 1, (alpha) | 0.0164606 |
| USP22 | ubiquitin specific peptidase 22 | 0.0164561 |
| KSR1 | kinase suppressor of ras 1 | 0.016432 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0159028 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0158613 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0158541 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0158386 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0157835 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0157089 |
| PCBP2 | poly(rC) binding protein 2 | 0.0156575 |
| ERBIN | erbb2 interacting protein | 0.0156441 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0153837 |
| RPS2 | ribosomal protein S2 | 0.0153789 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0152508 |
| KIF14 | kinesin family member 14 | 0.015187 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0150443 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | -0.240873 |
| NRG1 | neuregulin 1 | -0.233829 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.204132 |
| FN1 | fibronectin 1 | -0.167555 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.131361 |
| ASPH | aspartate beta-hydroxylase | -0.130064 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114871 |
| EFNA5 | ephrin-A5 | -0.0953392 |
| ITGA1 | integrin, alpha 1 | -0.0913981 |
| GLIS3 | GLIS family zinc finger 3 | -0.0904272 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0893229 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0811717 |
| NDRG1 | N-myc downstream regulated 1 | -0.0746493 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0613796 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0579367 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0570706 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0570057 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0568568 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0557253 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.053107 |
| TMEM156 | transmembrane protein 156 | -0.0518933 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0461334 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0428977 |
| EREG | epiregulin | -0.0421005 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0417591 |
| LOXL2 | lysyl oxidase-like 2 | -0.0415739 |
| HPCAL1 | hippocalcin-like 1 | -0.0412474 |
| DUSP6 | dual specificity phosphatase 6 | -0.0399869 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0399495 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0373292 |
| TMSB10 | thymosin beta 10 | -0.0362974 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0361845 |
| MT2A | metallothionein 2A | -0.0358063 |
| SMAD3 | SMAD family member 3 | -0.0357649 |
| RAI14 | retinoic acid induced 14 | -0.0351616 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0344444 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0338049 |
| CD44 | CD44 molecule (Indian blood group) | -0.033686 |
| NRP1 | neuropilin 1 | -0.0333658 |
| LMNA | lamin A/C | -0.0323625 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0320987 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.032003 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0317694 |
| EGFR | epidermal growth factor receptor | -0.03167 |
| ANKRD28 | ankyrin repeat domain 28 | -0.031391 |
| MTSS1 | metastasis suppressor 1 | -0.030603 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0301548 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0294153 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0290483 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0290125 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0289542 |
| SVIL | supervillin | -0.0288528 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0286729 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0286169 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0282669 |
| OXR1 | oxidation resistance 1 | -0.0281585 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0271104 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0270001 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0269803 |
| ATXN1 | ataxin 1 | -0.0265889 |
| NAV1 | neuron navigator 1 | -0.0264352 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0260085 |
| VEGFC | vascular endothelial growth factor C | -0.0258521 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0251597 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0251067 |
| EGR1 | early growth response 1 | -0.0250216 |
| MCL1 | myeloid cell leukemia 1 | -0.0246207 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0244286 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0243452 |
| HMGA1 | high mobility group AT-hook 1 | -0.0242914 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0241262 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0235767 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0233555 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0232626 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0229066 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.0225949 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.022551 |
| TMEM165 | transmembrane protein 165 | -0.0225182 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0222699 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0222623 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0219534 |
| FLNB | filamin B, beta | -0.0216267 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.021543 |
| PTK2 | protein tyrosine kinase 2 | -0.0215381 |
| MYADM | myeloid-associated differentiation marker | -0.0213696 |
| CDCP1 | CUB domain containing protein 1 | -0.0213319 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0211777 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0211677 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.021023 |
| SYT1 | synaptotagmin I | -0.0210101 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0208792 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0208004 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0204719 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0203488 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0202753 |
| KLF12 | Kruppel-like factor 12 | -0.0202509 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0201532 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0200856 |
| RAD51B | RAD51 paralog B | -0.0199322 |
| PRKCA | protein kinase C, alpha | -0.0193362 |