Pain, Postoperative Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010149
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Genes

220 genes/proteins associated with the disease Pain, Postoperative from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.88009
TNF tumor necrosis factor 2.23944
OPRM1 opioid receptor, mu 1 2.20399
IL6 interleukin 6 2.16131
IL1B interleukin 1, beta 2.12599
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.12414
CALCA calcitonin-related polypeptide alpha 2.09167
REN renin 2.0562
FOS FBJ murine osteosarcoma viral oncogene homolog 1.99523
NOS2 nitric oxide synthase 2, inducible 1.95661
IL10 interleukin 10 1.95465
CCL2 chemokine (C-C motif) ligand 2 1.93937
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.93582
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.9346
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.90771
MAPK1 mitogen-activated protein kinase 1 1.88589
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.87344
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.85992
MAPK3 mitogen-activated protein kinase 3 1.84782
GSK3B glycogen synthase kinase 3 beta 1.84499
CXCL8 chemokine (C-X-C motif) ligand 8 1.82849
OPRK1 opioid receptor, kappa 1 1.81593
SELL selectin L 1.79981
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.79637
POMC proopiomelanocortin 1.79044
TAC1 tachykinin, precursor 1 1.78416
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.77413
NGF nerve growth factor (beta polypeptide) 1.76385
CAT catalase 1.75915
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.73353
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.73332
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.72717
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.72571
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.7224
IL4 interleukin 4 1.71296
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.70927
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.70306
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.67268
CCND1 cyclin D1 1.66878
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.66533
SOD2 superoxide dismutase 2, mitochondrial 1.66274
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.64663
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.63586
ICAM1 intercellular adhesion molecule 1 1.63294
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.62624
OPRD1 opioid receptor, delta 1 1.61851
EDN1 endothelin 1 1.60221
MPO myeloperoxidase 1.59521
ALB albumin 1.59427
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.58279
BDNF brain-derived neurotrophic factor 1.56923
BAX BCL2-associated X protein 1.55995
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.55304
KNG1 kininogen 1 1.53892
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.52889
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.51734
CCL3 chemokine (C-C motif) ligand 3 1.51607
NPY neuropeptide Y 1.51105
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.50398
BCL2 B-cell CLL/lymphoma 2 1.49278
TLR4 toll-like receptor 4 1.48608
IFNG interferon, gamma 1.48402
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.48248
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.46595
CES2 carboxylesterase 2 1.46568
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.45458
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 1.45378
FAS Fas cell surface death receptor 1.45352
IL2 interleukin 2 1.44517
EPHX2 epoxide hydrolase 2, cytoplasmic 1.44001
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.43974
CXCL10 chemokine (C-X-C motif) ligand 10 1.43919
TGFA transforming growth factor, alpha 1.4332
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.42129
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.40595
MAPK14 mitogen-activated protein kinase 14 1.40176
EGFR epidermal growth factor receptor 1.40148
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.39507
CNR1 cannabinoid receptor 1 (brain) 1.39507
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.39282
PLAT plasminogen activator, tissue 1.39282
JUN jun proto-oncogene 1.38185
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.37705
TP53 tumor protein p53 1.3682
HMOX1 heme oxygenase 1 1.36706
EGR1 early growth response 1 1.36677
MMP9 matrix metallopeptidase 9 1.36476
IL1A interleukin 1, alpha 1.36047
NGFR nerve growth factor receptor 1.35531
PPARD peroxisome proliferator-activated receptor delta 1.35473
SPP1 secreted phosphoprotein 1 1.35069
TIMP1 TIMP metallopeptidase inhibitor 1 1.34955
BCL2L1 BCL2-like 1 1.3385
PRKCB protein kinase C, beta 1.33612
NOS1 nitric oxide synthase 1 (neuronal) 1.33464
DDIT3 DNA-damage-inducible transcript 3 1.3311
PPARA peroxisome proliferator-activated receptor alpha 1.32816
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.3231
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.31476
MMP2 matrix metallopeptidase 2 1.31059
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.30941
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.30512
VEGFA vascular endothelial growth factor A 1.30056
EDNRB endothelin receptor type B 1.29657
APP amyloid beta (A4) precursor protein 1.28518
APOE apolipoprotein E 1.28395
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.28088
CLU clusterin 1.27751
FGF2 fibroblast growth factor 2 (basic) 1.27595
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.27347
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.26083
TGFB1 transforming growth factor, beta 1 1.25494
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.25059
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.24997
IGF1 insulin-like growth factor 1 (somatomedin C) 1.24655
HSPA1A heat shock 70kDa protein 1A 1.24433
SDC4 syndecan 4 1.2368
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.21984
PRL prolactin 1.21887
ADRB2 adrenoceptor beta 2, surface 1.21695
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.20913
CDK2 cyclin-dependent kinase 2 1.20654
GUSB glucuronidase, beta 1.199
PDYN prodynorphin 1.19607
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.19542
PARP1 poly (ADP-ribose) polymerase 1 1.19509
CYCS cytochrome c, somatic 1.19379
CRH corticotropin releasing hormone 1.19345
MMP1 matrix metallopeptidase 1 1.18685
CTGF connective tissue growth factor 1.18685
PCNA proliferating cell nuclear antigen 1.1862
GCLC glutamate-cysteine ligase, catalytic subunit 1.18293
CREB1 cAMP responsive element binding protein 1 1.17993
GDF15 growth differentiation factor 15 1.1786
APOA1 apolipoprotein A-I 1.1786
GPX1 glutathione peroxidase 1 1.17761
BAK1 BCL2-antagonist/killer 1 1.17464
NQO1 NAD(P)H dehydrogenase, quinone 1 1.17464
PPARG peroxisome proliferator-activated receptor gamma 1.17366
CCL5 chemokine (C-C motif) ligand 5 1.17366
NCF1 neutrophil cytosolic factor 1 1.16666
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.16467
CRYAB crystallin, alpha B 1.16467
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.15899
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.15865
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.15865
VIP vasoactive intestinal peptide 1.15492
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.15492
TRIB3 tribbles pseudokinase 3 1.15458
DUSP1 dual specificity phosphatase 1 1.14644
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.14644
CAV1 caveolin 1, caveolae protein, 22kDa 1.14302
SARS seryl-tRNA synthetase 1.13758
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.13655
FASN fatty acid synthase 1.13621
FABP4 fatty acid binding protein 4, adipocyte 1.13552
MMP3 matrix metallopeptidase 3 1.13381
TRH thyrotropin-releasing hormone 1.13279
PYGL phosphorylase, glycogen, liver 1.13279
AKR1C3 aldo-keto reductase family 1, member C3 1.13211
GADD45A growth arrest and DNA-damage-inducible, alpha 1.13007
AKR1C1 aldo-keto reductase family 1, member C1 1.12461
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.12323
AVP arginine vasopressin 1.12185
GFAP glial fibrillary acidic protein 1.11606
S100A9 S100 calcium binding protein A9 1.11466
PDGFA platelet-derived growth factor alpha polypeptide 1.11466
EGF epidermal growth factor 1.1136
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.10527
ASIC3 acid sensing (proton gated) ion channel 3 1.10459
HDC histidine decarboxylase 1.10246
RB1 retinoblastoma 1 1.10069
GAST gastrin 1.09927
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.09611
PRKCE protein kinase C, epsilon 1.09401
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.09401
PENK proenkephalin 1.0919
CYP3A cytochrome P450, family 3, subfamily A 1.08975
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.08655
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.08442
TUBA1A tubulin, alpha 1a 1.08337
CYBB cytochrome b-245, beta polypeptide 1.08091
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 1.08055
ADRA2A adrenoceptor alpha 2A 1.08019
DUSP6 dual specificity phosphatase 6 1.0766
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.0766
HSPA8 heat shock 70kDa protein 8 1.07234
SAT1 spermidine/spermine N1-acetyltransferase 1 1.06844
ANGPTL4 angiopoietin-like 4 1.06588
PHGDH phosphoglycerate dehydrogenase 1.06515
PKLR pyruvate kinase, liver and RBC 1.06515
CDC42 cell division cycle 42 1.06225
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.06225
ANXA1 annexin A1 1.06188
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.05757
SOD1 superoxide dismutase 1, soluble 1.05648
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.05349
VIM vimentin 1.05163
ACO2 aconitase 2, mitochondrial 1.05089
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.04611
SELE selectin E 1.04352
CHRM3 cholinergic receptor, muscarinic 3 1.04276
CXCL2 chemokine (C-X-C motif) ligand 2 1.04276
HSF1 heat shock transcription factor 1 1.03976
TGFB3 transforming growth factor, beta 3 1.03976
THRSP thyroid hormone responsive 1.03976
BIRC5 baculoviral IAP repeat containing 5 1.03197
ADRA2B adrenoceptor alpha 2B 1.03159
PLIN2 perilipin 2 1.02634
FOXO1 forkhead box O1 1.02596
GSTM3 glutathione S-transferase mu 3 (brain) 1.02596
NKX2-1 NK2 homeobox 1 1.02447
CDK4 cyclin-dependent kinase 4 1.02188
TH tyrosine hydroxylase 1.0204
B2M beta-2-microglobulin 1.01852
HSPB1 heat shock 27kDa protein 1 1.01739
MSMO1 methylsterol monooxygenase 1 1.01587
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.01324
BACE1 beta-site APP-cleaving enzyme 1 1.01249
TIMP2 TIMP metallopeptidase inhibitor 2 1.01099