| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/115237 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Paliperidone relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF397 | zinc finger protein 397 | 0.71 |
| TMEM41B | transmembrane protein 41B | 0.7 |
| PLD6 | phospholipase D family, member 6 | 0.67 |
| REPIN1 | replication initiator 1 | 0.65 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.63 |
| ZNF799 | zinc finger protein 799 | 0.6 |
| ZNF669 | zinc finger protein 669 | 0.59 |
| TRIB1 | tribbles pseudokinase 1 | 0.54 |
| FLYWCH1 | FLYWCH-type zinc finger 1 | 0.54 |
| ZNF268 | zinc finger protein 268 | 0.53 |
| ZFP37 | ZFP37 zinc finger protein | 0.52 |
| RCOR2 | REST corepressor 2 | 0.52 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 0.46 |
| NEK4 | NIMA-related kinase 4 | 0.46 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | 0.46 |
| ZCCHC9 | zinc finger, CCHC domain containing 9 | 0.45 |
| CMC1 | C-x(9)-C motif containing 1 | 0.45 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 0.43 |
| TIFA | TRAF-interacting protein with forkhead-associated domain | 0.43 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.43 |
| TMEM192 | transmembrane protein 192 | 0.41 |
| RPL26 | ribosomal protein L26 | 0.41 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 | 0.4 |
| LCMT2 | leucine carboxyl methyltransferase 2 | 0.4 |
| HCFC2 | host cell factor C2 | 0.4 |
| CIAO2A | cytosolic iron-sulfur assembly component 2A | 0.4 |
| ZFP64 | ZFP64 zinc finger protein | 0.4 |
| SGMS2 | sphingomyelin synthase 2 | 0.4 |
| PALB2 | partner and localizer of BRCA2 | 0.39 |
| PRKX | protein kinase, X-linked | 0.39 |
| ZNF267 | zinc finger protein 267 | 0.38 |
| DIXDC1 | DIX domain containing 1 | 0.37 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.37 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 0.37 |
| SHROOM3 | shroom family member 3 | 0.36 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.36 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.35 |
| KLHDC8B | kelch domain containing 8B | 0.35 |
| BPTF | bromodomain PHD finger transcription factor | 0.34 |
| BOK | BCL2-related ovarian killer | 0.34 |
| E2F7 | E2F transcription factor 7 | 0.34 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit | 0.34 |
| WNK2 | WNK lysine deficient protein kinase 2 | 0.33 |
| GRAMD2B | GRAM domain containing 2B | 0.33 |
| TRIM37 | tripartite motif containing 37 | 0.33 |
| SENP7 | SUMO1/sentrin specific peptidase 7 | 0.33 |
| BAD | BCL2-associated agonist of cell death | 0.32 |
| SUSD1 | sushi domain containing 1 | 0.32 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.32 |
| ZNF317 | zinc finger protein 317 | 0.32 |
| ZNF22 | zinc finger protein 22 | 0.32 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.32 |
| ZFP91 | ZFP91 zinc finger protein | 0.32 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.31 |
| CEP290 | centrosomal protein 290kDa | 0.31 |
| DOLPP1 | dolichyldiphosphatase 1 | 0.31 |
| CAPN15 | calpain 15 | 0.31 |
| SRD5A3 | steroid 5 alpha-reductase 3 | 0.31 |
| OBSL1 | obscurin-like 1 | 0.3 |
| GPN3 | GPN-loop GTPase 3 | 0.3 |
| TRERF1 | transcriptional regulating factor 1 | 0.3 |
| NOVA2 | neuro-oncological ventral antigen 2 | 0.3 |
| TOMM40L | translocase of outer mitochondrial membrane 40 homolog (yeast)-like | 0.3 |
| TTC21B | tetratricopeptide repeat domain 21B | 0.29 |
| NLRX1 | NLR family member X1 | 0.29 |
| NPNT | nephronectin | 0.29 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.29 |
| CPE | carboxypeptidase E | 0.29 |
| TMEM9 | transmembrane protein 9 | 0.29 |
| PPP1R14C | protein phosphatase 1, regulatory (inhibitor) subunit 14C | 0.29 |
| ZC4H2 | zinc finger, C4H2 domain containing | 0.29 |
| ZNF264 | zinc finger protein 264 | 0.29 |
| COX11 | COX11 cytochrome c oxidase copper chaperone | 0.29 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 | 0.29 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.29 |
| CENPL | centromere protein L | 0.29 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 0.29 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | 0.29 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.28 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.28 |
| PRKD1 | protein kinase D1 | 0.28 |
| NOP16 | NOP16 nucleolar protein | 0.28 |
| KLHL8 | kelch-like family member 8 | 0.28 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.28 |
| KMT5A | lysine methyltransferase 5A | 0.28 |
| CKM | creatine kinase, muscle | 0.28 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.28 |
| DCLRE1B | DNA cross-link repair 1B | 0.28 |
| SLC2A4RG | SLC2A4 regulator | 0.28 |
| DPP4 | dipeptidyl-peptidase 4 | 0.27 |
| GLUL | glutamate-ammonia ligase | 0.27 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.27 |
| MAT1A | methionine adenosyltransferase I, alpha | 0.27 |
| NCKAP1L | NCK-associated protein 1-like | 0.27 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.26 |
| PUM1 | pumilio RNA-binding family member 1 | 0.26 |
| CYTH3 | cytohesin 3 | 0.26 |
| KLHL13 | kelch-like family member 13 | 0.26 |
| CEP55 | centrosomal protein 55kDa | 0.26 |
| LAMA5 | laminin, alpha 5 | 0.26 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARG2 | arginase 2 | -0.86 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.68 |
| PLEKHA8 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 | -0.68 |
| PXN | paxillin | -0.67 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | -0.64 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C | -0.63 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.57 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.56 |
| ABAT | 4-aminobutyrate aminotransferase | -0.55 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.55 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.55 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.54 |
| HSBP1 | heat shock factor binding protein 1 | -0.48 |
| CFAP36 | cilia and flagella associated protein 36 | -0.48 |
| MCRIP1 | MAPK regulated corepressor interacting protein 1 | -0.48 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.47 |
| PRMT2IP | PRMT2 interacting protein | -0.45 |
| JUN | jun proto-oncogene | -0.45 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.45 |
| HSP90AA4P | heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene | -0.45 |
| ANKRD26 | ankyrin repeat domain 26 | -0.44 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.43 |
| PYGO2 | pygopus family PHD finger 2 | -0.43 |
| RPS25 | ribosomal protein S25 | -0.43 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -0.42 |
| CCDC158 | coiled-coil domain containing 158 | -0.42 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.41 |
| DERPC | DERPC proline and glycine rich nuclear protein | -0.41 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.41 |
| HMOX1 | heme oxygenase 1 | -0.41 |
| ZNF428 | zinc finger protein 428 | -0.41 |
| ZYX | zyxin | -0.39 |
| ZNF823 | zinc finger protein 823 | -0.39 |
| F8 | coagulation factor VIII, procoagulant component | -0.39 |
| TMEM161A | transmembrane protein 161A | -0.39 |
| ACTBL2 | actin, beta-like 2 | -0.39 |
| ACTN4 | actinin, alpha 4 | -0.39 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.38 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.38 |
| ANKRD39 | ankyrin repeat domain 39 | -0.38 |
| PSAP | prosaposin | -0.37 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase | -0.37 |
| C1ORF52 | chromosome 1 open reading frame 52 | -0.37 |
| TSC22D4 | TSC22 domain family, member 4 | -0.36 |
| TPM4 | tropomyosin 4 | -0.36 |
| RGS19 | regulator of G-protein signaling 19 | -0.36 |
| DEAF1 | DEAF1 transcription factor | -0.36 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.35 |
| WTAP | Wilms tumor 1 associated protein | -0.35 |
| POLH | polymerase (DNA directed), eta | -0.35 |
| ZNF431 | zinc finger protein 431 | -0.35 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | -0.35 |
| CCDC117 | coiled-coil domain containing 117 | -0.35 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -0.34 |
| VTN | vitronectin | -0.34 |
| FBRSL1 | fibrosin-like 1 | -0.34 |
| TRAPPC6B | trafficking protein particle complex 6B | -0.34 |
| ZNF729 | zinc finger protein 729 | -0.34 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.34 |
| CPN1 | carboxypeptidase N, polypeptide 1 | -0.34 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | -0.33 |
| PRMT2 | protein arginine methyltransferase 2 | -0.33 |
| UBXN1 | UBX domain protein 1 | -0.33 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | -0.33 |
| ATXN1L | ataxin 1-like | -0.32 |
| RND3 | Rho family GTPase 3 | -0.32 |
| KIAA1191 | KIAA1191 | -0.32 |
| SLC44A2 | solute carrier family 44 (choline transporter), member 2 | -0.32 |
| HDGF | hepatoma-derived growth factor | -0.31 |
| METTL9 | methyltransferase like 9 | -0.31 |
| GDF15 | growth differentiation factor 15 | -0.31 |
| BCL9L | B-cell CLL/lymphoma 9-like | -0.31 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.31 |
| HBA1 | hemoglobin, alpha 1 | -0.31 |
| CARD19 | caspase recruitment domain family member 19 | -0.3 |
| CCDC85C | coiled-coil domain containing 85C | -0.3 |
| TET3 | tet methylcytosine dioxygenase 3 | -0.3 |
| CIR1 | corepressor interacting with RBPJ, 1 | -0.3 |
| MTF1 | metal-regulatory transcription factor 1 | -0.3 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.29 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | -0.29 |
| KIAA0753 | KIAA0753 | -0.29 |
| NOMO1 | NODAL modulator 1 | -0.29 |
| ENO1 | enolase 1, (alpha) | -0.29 |
| FAM89A | family with sequence similarity 89, member A | -0.29 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | -0.29 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -0.29 |
| EMD | emerin | -0.29 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.29 |
| TMEM183B | transmembrane protein 183B | -0.28 |
| ALPK3 | alpha-kinase 3 | -0.28 |
| RNASET2 | ribonuclease T2 | -0.28 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -0.28 |
| TSSC4 | tumor suppressing subtransferable candidate 4 | -0.28 |
| ANO10 | anoctamin 10 | -0.28 |
| PLCD1 | phospholipase C, delta 1 | -0.28 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.28 |
| CHURC1 | churchill domain containing 1 | -0.28 |
| MRPL50 | mitochondrial ribosomal protein L50 | -0.28 |
