| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.159098 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0981869 |
| NAV1 | neuron navigator 1 | 0.0924895 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0924198 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0903484 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.087228 |
| FN1 | fibronectin 1 | 0.0835249 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0815808 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.080104 |
| EFNA5 | ephrin-A5 | 0.0788776 |
| COL5A1 | collagen, type V, alpha 1 | 0.0772711 |
| MAP1B | microtubule-associated protein 1B | 0.074062 |
| ASPH | aspartate beta-hydroxylase | 0.0736846 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0621221 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0606614 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0605127 |
| VCL | vinculin | 0.0589608 |
| DST | dystonin | 0.0586723 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0583565 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0568847 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0561842 |
| CANX | calnexin | 0.0560572 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0557021 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0553049 |
| HDAC9 | histone deacetylase 9 | 0.0536027 |
| VEGFC | vascular endothelial growth factor C | 0.0525637 |
| PLXNA2 | plexin A2 | 0.0515338 |
| RIGI | RNA sensor RIG-I | 0.0513007 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0507559 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.050063 |
| TPM4 | tropomyosin 4 | 0.0496482 |
| FLNA | filamin A, alpha | 0.0491887 |
| EGFR | epidermal growth factor receptor | 0.0484652 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0476243 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0474839 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0467977 |
| SEPTIN9 | septin 9 | 0.0460732 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0456435 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0455905 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.045134 |
| FSTL1 | follistatin-like 1 | 0.044127 |
| TPM3 | tropomyosin 3 | 0.0435505 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.043433 |
| CYTH3 | cytohesin 3 | 0.0419835 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0414643 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0410957 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0410926 |
| CD44 | CD44 molecule (Indian blood group) | 0.0408308 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0407952 |
| ANXA2 | annexin A2 | 0.0407439 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0403036 |
| DCLK2 | doublecortin-like kinase 2 | 0.0402417 |
| SP100 | SP100 nuclear antigen | 0.0400649 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0391716 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.038721 |
| INTS6 | integrator complex subunit 6 | 0.0387033 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0382773 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0381314 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.038125 |
| GLIS3 | GLIS family zinc finger 3 | 0.0375347 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0374207 |
| PCDH7 | protocadherin 7 | 0.0372606 |
| MCL1 | myeloid cell leukemia 1 | 0.036963 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0362005 |
| RASAL2 | RAS protein activator like 2 | 0.0361929 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0355597 |
| CUX1 | cut-like homeobox 1 | 0.0354677 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0349211 |
| KIAA1549L | KIAA1549-like | 0.0346459 |
| NEK7 | NIMA-related kinase 7 | 0.0330322 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0329342 |
| PRSS23 | protease, serine, 23 | 0.0325411 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0322693 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0320954 |
| DIAPH3 | diaphanous-related formin 3 | 0.0320421 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0319344 |
| LRRC17 | leucine rich repeat containing 17 | 0.031403 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0309996 |
| MSN | moesin | 0.0309954 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0306862 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0305088 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0302702 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0300158 |
| DSPP | dentin sialophosphoprotein | 0.0295305 |
| FMN2 | formin 2 | 0.0293097 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0287729 |
| DNMBP | dynamin binding protein | 0.0285988 |
| SMAD3 | SMAD family member 3 | 0.0279924 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0277664 |
| RRM2 | ribonucleotide reductase M2 | 0.0277348 |
| ERBIN | erbb2 interacting protein | 0.0275415 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0266786 |
| TRABD2B | TraB domain containing 2B | 0.026226 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0259835 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0259196 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0259053 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0257039 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0252502 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0250553 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0250541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.243307 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.20784 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.142585 |
| NDRG1 | N-myc downstream regulated 1 | -0.14075 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.135606 |
| FBN1 | fibrillin 1 | -0.112329 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.111989 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.110112 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0941103 |
| LOXL2 | lysyl oxidase-like 2 | -0.0883094 |
| COL1A2 | collagen, type I, alpha 2 | -0.0814715 |
| COL3A1 | collagen, type III, alpha 1 | -0.0684693 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0655581 |
| VIM | vimentin | -0.0619995 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.056096 |
| PTMA | prothymosin, alpha | -0.055445 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0550755 |
| GPC6 | glypican 6 | -0.0534295 |
| MT2A | metallothionein 2A | -0.0528246 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527353 |
| SBF2 | SET binding factor 2 | -0.0523694 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0517738 |
| GOLGA4 | golgin A4 | -0.0498728 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0458986 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0455851 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0449257 |
| TMSB4X | thymosin beta 4, X-linked | -0.0444927 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0429708 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.040231 |
| LOX | lysyl oxidase | -0.0400175 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.039842 |
| UBC | ubiquitin C | -0.0388701 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0387742 |
| HLA-B | major histocompatibility complex, class I, B | -0.0371015 |
| STC1 | stanniocalcin 1 | -0.0356696 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0355909 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0355102 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0350544 |
| RPS6 | ribosomal protein S6 | -0.0340579 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0337364 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0335486 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0334759 |
| RPL35A | ribosomal protein L35a | -0.0332183 |
| OPTN | optineurin | -0.0325315 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0320017 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0318995 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0312738 |
| INSIG1 | insulin induced gene 1 | -0.0312128 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.03105 |
| S100A6 | S100 calcium binding protein A6 | -0.0307877 |
| THBS2 | thrombospondin 2 | -0.0306222 |
| CD109 | CD109 molecule | -0.0305284 |
| AUTS2 | autism susceptibility candidate 2 | -0.0294963 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0294033 |
| GNAS | GNAS complex locus | -0.0288583 |
| LRRC49 | leucine rich repeat containing 49 | -0.0287245 |
| RPS24 | ribosomal protein S24 | -0.0285735 |
| ATP13A3 | ATPase type 13A3 | -0.0285401 |
| CSTB | cystatin B (stefin B) | -0.0284193 |
| SQSTM1 | sequestosome 1 | -0.0283704 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282925 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0278748 |
| LMNA | lamin A/C | -0.0278521 |
| OGA | O-GlcNAcase | -0.0278211 |
| S100A10 | S100 calcium binding protein A10 | -0.0276497 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0276266 |
| FTL | ferritin, light polypeptide | -0.0273299 |
| FNIP1 | folliculin interacting protein 1 | -0.0271707 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0265266 |
| RPS19 | ribosomal protein S19 | -0.0262432 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0262077 |
| WTAP | Wilms tumor 1 associated protein | -0.0262071 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0260766 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0260598 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0253925 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0250529 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0248997 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0248262 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0246604 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0245087 |
| C1D | C1D nuclear receptor corepressor | -0.0243946 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0243222 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0236287 |
| CD99 | CD99 molecule | -0.0233095 |
| ZNF292 | zinc finger protein 292 | -0.0233045 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.023287 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0231916 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0231675 |
| FRMD5 | FERM domain containing 5 | -0.023085 |
| TMOD1 | tropomodulin 1 | -0.0229202 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0227701 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0226858 |
| RHOQ | ras homolog family member Q | -0.0224446 |
| CLU | clusterin | -0.0221938 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0220306 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0218843 |
| HLA-E | major histocompatibility complex, class I, E | -0.021821 |
| MMP12 | matrix metallopeptidase 12 | -0.0214958 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0214883 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0211879 |