| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.26222 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.235373 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.229054 |
| HMGA2 | high mobility group AT-hook 2 | 0.129552 |
| YAP1 | Yes-associated protein 1 | 0.102166 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0982161 |
| DST | dystonin | 0.0969337 |
| MMP12 | matrix metallopeptidase 12 | 0.0901856 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0867746 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0842103 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0821221 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0801166 |
| JMJD1C | jumonji domain containing 1C | 0.0772424 |
| SMC4 | structural maintenance of chromosomes 4 | 0.074187 |
| NHSL1 | NHS-like 1 | 0.0741782 |
| PCDH7 | protocadherin 7 | 0.0732177 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0720186 |
| PDGFC | platelet derived growth factor C | 0.070775 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0660973 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0650417 |
| RRM2 | ribonucleotide reductase M2 | 0.063342 |
| EHBP1 | EH domain binding protein 1 | 0.0594066 |
| ASPH | aspartate beta-hydroxylase | 0.0568395 |
| MTAP | methylthioadenosine phosphorylase | 0.0546163 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0532297 |
| ZNF804A | zinc finger protein 804A | 0.0527584 |
| RASAL2 | RAS protein activator like 2 | 0.0516967 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0513068 |
| ADIPOR2 | adiponectin receptor 2 | 0.0510246 |
| EDARADD | EDAR-associated death domain | 0.0494454 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0487681 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0479245 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0477003 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0476285 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0468252 |
| CANX | calnexin | 0.046467 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0458283 |
| TENM3 | teneurin transmembrane protein 3 | 0.0458018 |
| RTN4 | reticulon 4 | 0.0457286 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0454492 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0452975 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0450683 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0446385 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.044455 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0437509 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0432189 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0428955 |
| CMIP | c-Maf inducing protein | 0.0427907 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0423272 |
| BCHE | butyrylcholinesterase | 0.0423116 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0420514 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0390376 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0389192 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0387559 |
| ERBIN | erbb2 interacting protein | 0.037221 |
| CALR | calreticulin | 0.0372104 |
| NEBL | nebulette | 0.0370201 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.036494 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0364312 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0357501 |
| CLTC | clathrin, heavy chain (Hc) | 0.0354942 |
| INTS6 | integrator complex subunit 6 | 0.0351884 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0346027 |
| MYPN | myopalladin | 0.0345137 |
| VCL | vinculin | 0.0344994 |
| CUX1 | cut-like homeobox 1 | 0.034397 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0340531 |
| TPM3 | tropomyosin 3 | 0.0339747 |
| USP34 | ubiquitin specific peptidase 34 | 0.0337585 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.033439 |
| CENPF | centromere protein F, 350/400kDa | 0.0334178 |
| TMEM41B | transmembrane protein 41B | 0.0333442 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0332863 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0332454 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0330444 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0326957 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0326286 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0325248 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0322304 |
| CEP112 | centrosomal protein 112kDa | 0.0322159 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0318861 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0318814 |
| PRKCE | protein kinase C, epsilon | 0.0317704 |
| MKI67 | marker of proliferation Ki-67 | 0.0313411 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0310365 |
| MAP1B | microtubule-associated protein 1B | 0.0309413 |
| XPOT | exportin, tRNA | 0.0305729 |
| EXOC4 | exocyst complex component 4 | 0.0302459 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0299007 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.029538 |
| NAV3 | neuron navigator 3 | 0.029312 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0292868 |
| SFPQ | splicing factor proline/glutamine-rich | 0.028985 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.028967 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0287916 |
| RAB10 | RAB10, member RAS oncogene family | 0.0287411 |
| SETX | senataxin | 0.0283297 |
| VMP1 | vacuole membrane protein 1 | 0.0283014 |
| NEGR1 | neuronal growth regulator 1 | 0.0281664 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0281247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.123246 |
| VIM | vimentin | -0.0857351 |
| FTL | ferritin, light polypeptide | -0.066125 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0652863 |
| AREG | amphiregulin | -0.0650077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0564502 |
| RPS6 | ribosomal protein S6 | -0.0528305 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.044963 |
| RPS19 | ribosomal protein S19 | -0.0407676 |
| RPL23 | ribosomal protein L23 | -0.0406098 |
| PFN1 | profilin 1 | -0.0383947 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.036342 |
| RPL12 | ribosomal protein L12 | -0.0345641 |
| RPL35A | ribosomal protein L35a | -0.0339278 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0329965 |
| HSPB1 | heat shock 27kDa protein 1 | -0.029229 |
| RPL19 | ribosomal protein L19 | -0.0285118 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0284256 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0276552 |
| RPS3 | ribosomal protein S3 | -0.0269737 |
| EDN1 | endothelin 1 | -0.0257081 |
| RPL8 | ribosomal protein L8 | -0.0254663 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0253801 |
| HMGA1 | high mobility group AT-hook 1 | -0.0244891 |
| MGAT4C | MGAT4 family, member C | -0.0243196 |
| RPLP1 | ribosomal protein, large, P1 | -0.0243058 |
| KLHL24 | kelch-like family member 24 | -0.0229805 |
| RPL36 | ribosomal protein L36 | -0.0228785 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0221613 |
| RPS16 | ribosomal protein S16 | -0.0220498 |
| PTMS | parathymosin | -0.0220419 |
| RPL26 | ribosomal protein L26 | -0.021953 |
| PTMA | prothymosin, alpha | -0.0219276 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0218167 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0216806 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0215871 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0213415 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0208151 |
| RPS23 | ribosomal protein S23 | -0.0207196 |
| RPL34 | ribosomal protein L34 | -0.0205896 |
| RPL28 | ribosomal protein L28 | -0.0200617 |
| RPS25 | ribosomal protein S25 | -0.019887 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0195886 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0192457 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0190524 |
| RPL32 | ribosomal protein L32 | -0.0187499 |
| RPS24 | ribosomal protein S24 | -0.0186764 |
| MATR3 | matrin 3 | -0.0182644 |
| BTG3 | BTG family, member 3 | -0.0182333 |
| RPL31 | ribosomal protein L31 | -0.0182119 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0181538 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0180886 |
| RACK1 | receptor for activated C kinase 1 | -0.0180009 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0179614 |
| S100A6 | S100 calcium binding protein A6 | -0.0179191 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0176936 |
| YBX1 | Y box binding protein 1 | -0.0174213 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0173949 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0170482 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0168527 |
| RPL37 | ribosomal protein L37 | -0.0164463 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0160101 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0159035 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0157696 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0156025 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0155987 |
| RPS21 | ribosomal protein S21 | -0.0154298 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0153501 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0152374 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0151582 |
| RPS5 | ribosomal protein S5 | -0.0147424 |
| RPL27A | ribosomal protein L27a | -0.0144939 |
| RPS8 | ribosomal protein S8 | -0.0144903 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0144721 |
| RPL11 | ribosomal protein L11 | -0.014276 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0141972 |
| RPL36A | ribosomal protein L36a | -0.0141732 |
| RPS14 | ribosomal protein S14 | -0.0140039 |
| RPL38 | ribosomal protein L38 | -0.0137911 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0135062 |
| ASTN2 | astrotactin 2 | -0.0131889 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0130937 |
| CPOX | coproporphyrinogen oxidase | -0.0129557 |
| RPL18 | ribosomal protein L18 | -0.0129529 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0129381 |
| RPS4X | ribosomal protein S4, X-linked | -0.0129129 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0128017 |
| ZNF292 | zinc finger protein 292 | -0.0127434 |
| H1-0 | H1.0 linker histone | -0.0127354 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0125599 |
| RPL5 | ribosomal protein L5 | -0.0125059 |
| RPL3 | ribosomal protein L3 | -0.0122775 |
| THOC1 | THO complex 1 | -0.0122114 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0121889 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0120153 |
| HLA-A | major histocompatibility complex, class I, A | -0.0119871 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0118977 |
| RPS11 | ribosomal protein S11 | -0.01176 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.0117137 |
| VAT1 | vesicle amine transport 1 | -0.0115376 |
