| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.08703 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0764634 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0682978 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0681202 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0626072 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0609164 |
| VCL | vinculin | 0.055049 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0503778 |
| NAV2 | neuron navigator 2 | 0.0499974 |
| RIGI | RNA sensor RIG-I | 0.0493851 |
| KYNU | kynureninase | 0.0484056 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0470392 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0469005 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0464451 |
| FRMD4A | FERM domain containing 4A | 0.0459623 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0458924 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0450959 |
| RNF213 | ring finger protein 213 | 0.0440601 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0434888 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0431529 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0429292 |
| RAI14 | retinoic acid induced 14 | 0.0403246 |
| SMAD3 | SMAD family member 3 | 0.037758 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0363297 |
| FAT1 | FAT atypical cadherin 1 | 0.0350751 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0350231 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0339589 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.033871 |
| CALU | calumenin | 0.0337803 |
| HDAC9 | histone deacetylase 9 | 0.0337167 |
| INTS6 | integrator complex subunit 6 | 0.0331919 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0331572 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0328622 |
| MX1 | MX dynamin-like GTPase 1 | 0.032509 |
| ANXA2 | annexin A2 | 0.0324137 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0320746 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0314557 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0309964 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.030615 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0305697 |
| TGM2 | transglutaminase 2 | 0.0304733 |
| MYOF | myoferlin | 0.0303897 |
| GPC6 | glypican 6 | 0.0300442 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0300001 |
| JAK1 | Janus kinase 1 | 0.0288773 |
| GOLGB1 | golgin B1 | 0.0282372 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0281937 |
| DST | dystonin | 0.0279099 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0272708 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0265029 |
| RRM2 | ribonucleotide reductase M2 | 0.0264848 |
| CTBP2 | C-terminal binding protein 2 | 0.0264632 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0263952 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0263034 |
| EXOC4 | exocyst complex component 4 | 0.0261839 |
| CD44 | CD44 molecule (Indian blood group) | 0.0260115 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0257802 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.025671 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.025297 |
| GLIS3 | GLIS family zinc finger 3 | 0.025006 |
| TUT7 | terminal uridylyl transferase 7 | 0.0247278 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0245819 |
| SP100 | SP100 nuclear antigen | 0.0242932 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0241993 |
| MYO1E | myosin IE | 0.0239288 |
| RAD51B | RAD51 paralog B | 0.0234646 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0234323 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0234233 |
| PAX8 | paired box 8 | 0.0232459 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0231611 |
| DIAPH3 | diaphanous-related formin 3 | 0.0230703 |
| IFI44L | interferon-induced protein 44-like | 0.0229932 |
| RPS2 | ribosomal protein S2 | 0.0223099 |
| ZNF644 | zinc finger protein 644 | 0.0222706 |
| FRMD5 | FERM domain containing 5 | 0.0221604 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0221412 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0217128 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0216216 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0215938 |
| EGFR | epidermal growth factor receptor | 0.0215859 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0212158 |
| UBAP2 | ubiquitin associated protein 2 | 0.0211267 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0210967 |
| PLEC | plectin | 0.0209865 |
| PALLD | palladin, cytoskeletal associated protein | 0.0209737 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.020691 |
| LYST | lysosomal trafficking regulator | 0.0205339 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.020442 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0202588 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0201313 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.01992 |
| CANX | calnexin | 0.0197269 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0196419 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0194257 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0192237 |
| NRP2 | neuropilin 2 | 0.0190938 |
| SLFN5 | schlafen family member 5 | 0.0190616 |
| EFNA5 | ephrin-A5 | 0.0189381 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0188824 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.018731 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.206322 |
| VIM | vimentin | -0.15341 |
| FTL | ferritin, light polypeptide | -0.148302 |
| RPS6 | ribosomal protein S6 | -0.111721 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.106402 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0975028 |
| POTEF | POTE ankyrin domain family, member F | -0.0876419 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0839464 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0731471 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0698374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0682705 |
| PTMA | prothymosin, alpha | -0.0678122 |
| RPL35A | ribosomal protein L35a | -0.0654416 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0634292 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0631224 |
| RPS19 | ribosomal protein S19 | -0.0605725 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0586779 |
| NDRG1 | N-myc downstream regulated 1 | -0.0565934 |
| RPL23 | ribosomal protein L23 | -0.0562058 |
| PFN1 | profilin 1 | -0.055759 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0543047 |
| MT2A | metallothionein 2A | -0.050728 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0492094 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0479215 |
| RPS4X | ribosomal protein S4, X-linked | -0.0473885 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0469419 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0459695 |
| RPLP2 | ribosomal protein, large, P2 | -0.0449978 |
| RPS24 | ribosomal protein S24 | -0.0445472 |
| GDF15 | growth differentiation factor 15 | -0.0443701 |
| CTSD | cathepsin D | -0.0441479 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0429779 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0426847 |
| RPL34 | ribosomal protein L34 | -0.042653 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0420924 |
| RPS8 | ribosomal protein S8 | -0.0412841 |
| RPS5 | ribosomal protein S5 | -0.0410156 |
| RPL8 | ribosomal protein L8 | -0.0394851 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394733 |
| RPS21 | ribosomal protein S21 | -0.0387765 |
| RPL28 | ribosomal protein L28 | -0.0386269 |
| RPLP1 | ribosomal protein, large, P1 | -0.038345 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0372423 |
| RPL31 | ribosomal protein L31 | -0.0366481 |
| ACTG1 | actin gamma 1 | -0.0350278 |
| IRS2 | insulin receptor substrate 2 | -0.034868 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0347556 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0346311 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0343319 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0342327 |
| RPL19 | ribosomal protein L19 | -0.0338583 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0335546 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0333454 |
| INSIG1 | insulin induced gene 1 | -0.0325553 |
| CBX3 | chromobox homolog 3 | -0.0320962 |
| DSTN | destrin (actin depolymerizing factor) | -0.0320569 |
| TKT | transketolase | -0.0318235 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0307417 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0306718 |
| RPS13 | ribosomal protein S13 | -0.0306345 |
| GNAS | GNAS complex locus | -0.0301592 |
| RPS14 | ribosomal protein S14 | -0.0299317 |
| RPL37A | ribosomal protein L37a | -0.0291963 |
| RPL5 | ribosomal protein L5 | -0.0286827 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0286226 |
| CP | ceruloplasmin (ferroxidase) | -0.0283853 |
| ANKRD10 | ankyrin repeat domain 10 | -0.028138 |
| RPS23 | ribosomal protein S23 | -0.0277741 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0276698 |
| CADM1 | cell adhesion molecule 1 | -0.0276474 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0275036 |
| RPL36A | ribosomal protein L36a | -0.027441 |
| SERF2 | small EDRK-rich factor 2 | -0.0273302 |
| RPS11 | ribosomal protein S11 | -0.0270967 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0270345 |
| CXXC1 | CXXC finger protein 1 | -0.0268962 |
| GOLGA4 | golgin A4 | -0.0268503 |
| RPL32 | ribosomal protein L32 | -0.0265481 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.026435 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.026352 |
| G0S2 | G0/G1 switch 2 | -0.0262838 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0262562 |
| SP3 | Sp3 transcription factor | -0.0260525 |
| RPS16 | ribosomal protein S16 | -0.0259086 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0258458 |
| USP3 | ubiquitin specific peptidase 3 | -0.0256609 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0251499 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0251439 |
| S100A6 | S100 calcium binding protein A6 | -0.0249527 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.024746 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0247458 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.024562 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0245035 |
| PKM | pyruvate kinase, muscle | -0.0244364 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0244024 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.02439 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.024374 |
| RPS27A | ribosomal protein S27a | -0.0243401 |
| HLA-B | major histocompatibility complex, class I, B | -0.0243399 |
| DENND2B | DENN domain containing 2B | -0.0242346 |
