| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.182293 |
| ANXA2 | annexin A2 | 0.106586 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0814713 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0806692 |
| KYNU | kynureninase | 0.0751728 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0729197 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0666591 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0644043 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0643215 |
| RPS2 | ribosomal protein S2 | 0.0617541 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0610794 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0608537 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0591824 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0584855 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0580057 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0576887 |
| STC1 | stanniocalcin 1 | 0.0573939 |
| MCL1 | myeloid cell leukemia 1 | 0.0552009 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0529601 |
| PCBP2 | poly(rC) binding protein 2 | 0.0528327 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.051781 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0512792 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0498697 |
| FAM107B | family with sequence similarity 107, member B | 0.0496657 |
| VCL | vinculin | 0.0487683 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0465406 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0449357 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0432131 |
| WWOX | WW domain containing oxidoreductase | 0.0426451 |
| TGM2 | transglutaminase 2 | 0.04259 |
| PDLIM5 | PDZ and LIM domain 5 | 0.041174 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0400809 |
| AXL | AXL receptor tyrosine kinase | 0.0398097 |
| LDHA | lactate dehydrogenase A | 0.0397788 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0396959 |
| SEPTIN9 | septin 9 | 0.0390714 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0383376 |
| RHCG | Rh family, C glycoprotein | 0.0378621 |
| GRAMD1B | GRAM domain containing 1B | 0.0377665 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0370855 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0366774 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.036232 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0350011 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0344504 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0344028 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0343147 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.033682 |
| CMIP | c-Maf inducing protein | 0.0331581 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0328348 |
| MSN | moesin | 0.0325088 |
| RPL13A | ribosomal protein L13a | 0.0323497 |
| LMO7 | LIM domain 7 | 0.0322847 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0318535 |
| BPTF | bromodomain PHD finger transcription factor | 0.0316228 |
| FAT1 | FAT atypical cadherin 1 | 0.0312711 |
| WWC1 | WW and C2 domain containing 1 | 0.0312137 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0309926 |
| RPL7 | ribosomal protein L7 | 0.0309907 |
| BMP6 | bone morphogenetic protein 6 | 0.0298984 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0298459 |
| FLNA | filamin A, alpha | 0.0296495 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0296299 |
| VMP1 | vacuole membrane protein 1 | 0.0294742 |
| INTS6 | integrator complex subunit 6 | 0.0292923 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0292471 |
| PDE10A | phosphodiesterase 10A | 0.0287116 |
| RPS8 | ribosomal protein S8 | 0.0285814 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0283468 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0279938 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0278378 |
| RPLP0 | ribosomal protein, large, P0 | 0.0277957 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0276231 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0275588 |
| TJP1 | tight junction protein 1 | 0.0265099 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0263928 |
| BRD2 | bromodomain containing 2 | 0.0263175 |
| POTEF | POTE ankyrin domain family, member F | 0.0259183 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0257273 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0255086 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024703 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0246971 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0246848 |
| SQSTM1 | sequestosome 1 | 0.0246221 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0244497 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0243554 |
| TPM3 | tropomyosin 3 | 0.0240438 |
| FERMT2 | fermitin family member 2 | 0.0238081 |
| GPATCH2L | G patch domain containing 2-like | 0.0237826 |
| CENPF | centromere protein F, 350/400kDa | 0.0235072 |
| SMYD3 | SET and MYND domain containing 3 | 0.0232777 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0232251 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0231673 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0229733 |
| ENO1 | enolase 1, (alpha) | 0.0227539 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0225542 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0225363 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.022512 |
| RTN4 | reticulon 4 | 0.0224025 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0223471 |
| SET | SET nuclear proto-oncogene | 0.0221633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.241908 |
| NDRG1 | N-myc downstream regulated 1 | -0.201112 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.190397 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.175535 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.103842 |
| CA12 | carbonic anhydrase XII | -0.0860903 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0808086 |
| RIN2 | Ras and Rab interactor 2 | -0.0733411 |
| AHNAK | AHNAK nucleoprotein | -0.0684568 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0683243 |
| RNF213 | ring finger protein 213 | -0.0661197 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0647994 |
| EHBP1 | EH domain binding protein 1 | -0.0643797 |
| MT1X | metallothionein 1X | -0.0635686 |
| ANXA4 | annexin A4 | -0.0610225 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0607919 |
| TNS3 | tensin 3 | -0.0599149 |
| USP3 | ubiquitin specific peptidase 3 | -0.0593003 |
| RPS19 | ribosomal protein S19 | -0.0577057 |
| FLNB | filamin B, beta | -0.0562333 |
| AUTS2 | autism susceptibility candidate 2 | -0.054849 |
| RRBP1 | ribosome binding protein 1 | -0.0502804 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0491045 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0488927 |
| DAPK1 | death-associated protein kinase 1 | -0.0485265 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0481708 |
| EFNA5 | ephrin-A5 | -0.046375 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0463579 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0461031 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0453567 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0452889 |
| RAI14 | retinoic acid induced 14 | -0.0451296 |
| H1-0 | H1.0 linker histone | -0.0447075 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0444374 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0441166 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0429509 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0429011 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0407394 |
| FTL | ferritin, light polypeptide | -0.0404338 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0399746 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0394718 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0390181 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0371778 |
| TMSB4X | thymosin beta 4, X-linked | -0.0368958 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0368835 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.035556 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0350325 |
| CP | ceruloplasmin (ferroxidase) | -0.0350228 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0338918 |
| PRKCA | protein kinase C, alpha | -0.0338076 |
| S100A10 | S100 calcium binding protein A10 | -0.032547 |
| FAM13A | family with sequence similarity 13, member A | -0.0325028 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0323475 |
| PCED1B | PC-esterase domain containing 1B | -0.0321738 |
| PHF21A | PHD finger protein 21A | -0.0316598 |
| PTMA | prothymosin, alpha | -0.0315162 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0314843 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0305187 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0302807 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0299373 |
| MAP1B | microtubule-associated protein 1B | -0.0296357 |
| KLF6 | Kruppel-like factor 6 | -0.0294915 |
| TCF12 | transcription factor 12 | -0.0289071 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0288468 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0288294 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0288213 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0285933 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0285024 |
| RGS17 | regulator of G-protein signaling 17 | -0.0282541 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0281855 |
| SBF2 | SET binding factor 2 | -0.0281611 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0274805 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0273932 |
| RPL32 | ribosomal protein L32 | -0.0272863 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0272321 |
| DENND4C | DENN/MADD domain containing 4C | -0.0272057 |
| RPS24 | ribosomal protein S24 | -0.0266096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0261406 |
| DENND5B | DENN/MADD domain containing 5B | -0.0258602 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0256403 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0253077 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0252972 |
| TPM1 | tropomyosin 1 (alpha) | -0.025116 |
| LAMB3 | laminin, beta 3 | -0.0248721 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0247424 |
| FMNL2 | formin-like 2 | -0.0246533 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0246209 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0244711 |
| NRP1 | neuropilin 1 | -0.0244556 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0237047 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0236452 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.023478 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0233477 |
| TKT | transketolase | -0.0230325 |
| ETV6 | ets variant 6 | -0.0228321 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0227125 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0224702 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0224594 |
| RIGI | RNA sensor RIG-I | -0.0223812 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0223364 |
