| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0894797 |
| EGFR | epidermal growth factor receptor | 0.0706102 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0685828 |
| FNDC3B | fibronectin type III domain containing 3B | 0.061186 |
| SMAD3 | SMAD family member 3 | 0.061011 |
| EFNA5 | ephrin-A5 | 0.0560683 |
| MYOF | myoferlin | 0.0548697 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0541657 |
| LAMA4 | laminin, alpha 4 | 0.0539738 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0495947 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0493442 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0490138 |
| VCL | vinculin | 0.0458965 |
| ITGA6 | integrin, alpha 6 | 0.0454433 |
| HMGA2 | high mobility group AT-hook 2 | 0.0445992 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0440355 |
| BCL2L1 | BCL2-like 1 | 0.0440183 |
| FLNB | filamin B, beta | 0.0425136 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0423478 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0421032 |
| RASAL2 | RAS protein activator like 2 | 0.0420188 |
| TGM2 | transglutaminase 2 | 0.041611 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0415774 |
| EHBP1 | EH domain binding protein 1 | 0.041541 |
| VCAN | versican | 0.0399684 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0398003 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0390445 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0373188 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0364108 |
| ERBIN | erbb2 interacting protein | 0.0359959 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0357037 |
| INTS6 | integrator complex subunit 6 | 0.0351049 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0349222 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0346111 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0345243 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0341693 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0339427 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0333452 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0331132 |
| MED13L | mediator complex subunit 13-like | 0.0330847 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0327303 |
| RCOR1 | REST corepressor 1 | 0.0321749 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321749 |
| MYO1E | myosin IE | 0.0316369 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0314735 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0310833 |
| TMEM164 | transmembrane protein 164 | 0.0309078 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.030778 |
| PRELID2 | PRELI domain containing 2 | 0.0303055 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.030112 |
| SEPTIN9 | septin 9 | 0.0287061 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0282171 |
| FAT1 | FAT atypical cadherin 1 | 0.0279603 |
| DSPP | dentin sialophosphoprotein | 0.0278912 |
| FBXO11 | F-box protein 11 | 0.0277528 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0268667 |
| CAB39 | calcium binding protein 39 | 0.0263646 |
| SLC38A2 | solute carrier family 38, member 2 | 0.026111 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0259899 |
| WWC1 | WW and C2 domain containing 1 | 0.0259582 |
| CD44 | CD44 molecule (Indian blood group) | 0.0259098 |
| PTK2 | protein tyrosine kinase 2 | 0.0250738 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0248448 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0245391 |
| CAPRIN2 | caprin family member 2 | 0.0242992 |
| PLEC | plectin | 0.0242577 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0240181 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0239642 |
| TJP1 | tight junction protein 1 | 0.0238877 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0236048 |
| CORO1C | coronin, actin binding protein, 1C | 0.0233252 |
| ANXA11 | annexin A11 | 0.0232457 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0230655 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0230635 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0229708 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.02279 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0226233 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0224722 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0223797 |
| SERTAD2 | SERTA domain containing 2 | 0.0222249 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0222126 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0221837 |
| ACTN4 | actinin, alpha 4 | 0.0217463 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0216338 |
| DST | dystonin | 0.0214149 |
| MCL1 | myeloid cell leukemia 1 | 0.0213964 |
| FOXO1 | forkhead box O1 | 0.021124 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.020974 |
| AHNAK | AHNAK nucleoprotein | 0.0204215 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0203897 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0202001 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0201964 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0201627 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0199725 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0196066 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0193897 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0190485 |
| AREG | amphiregulin | 0.018827 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0187669 |
| CCNY | cyclin Y | 0.0184974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.301626 |
| TMSB10 | thymosin beta 10 | -0.25765 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.177755 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.162148 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.139824 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.122376 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.116567 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.116272 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.11584 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0997158 |
| TXNRD1 | thioredoxin reductase 1 | -0.0992744 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0989987 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0978581 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0970609 |
| FTL | ferritin, light polypeptide | -0.0948549 |
| VIM | vimentin | -0.0873922 |
| NDRG1 | N-myc downstream regulated 1 | -0.0855638 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0808629 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0803598 |
| RPL35A | ribosomal protein L35a | -0.0713466 |
| MXD1 | MAX dimerization protein 1 | -0.0674894 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0665556 |
| B2M | beta-2-microglobulin | -0.066157 |
| KLK10 | kallikrein-related peptidase 10 | -0.0659286 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0592561 |
| GOLGA4 | golgin A4 | -0.0587962 |
| TPM4 | tropomyosin 4 | -0.0570062 |
| PGK1 | phosphoglycerate kinase 1 | -0.0552051 |
| PTMA | prothymosin, alpha | -0.0551575 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0550898 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0530786 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0517742 |
| RRBP1 | ribosome binding protein 1 | -0.0511509 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0507544 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0499629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.049888 |
| GNAS | GNAS complex locus | -0.0494804 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0487336 |
| RPL34 | ribosomal protein L34 | -0.0486534 |
| LMO7 | LIM domain 7 | -0.0486097 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0464143 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0461027 |
| EGR1 | early growth response 1 | -0.0460087 |
| TXNIP | thioredoxin interacting protein | -0.045204 |
| RIOK3 | RIO kinase 3 | -0.0450382 |
| RPL31 | ribosomal protein L31 | -0.043064 |
| RPS6 | ribosomal protein S6 | -0.0423365 |
| MORF4L2 | mortality factor 4 like 2 | -0.0416671 |
| RPLP1 | ribosomal protein, large, P1 | -0.0411083 |
| UPP1 | uridine phosphorylase 1 | -0.0410282 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.040511 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0396906 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0380555 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0380314 |
| S100A6 | S100 calcium binding protein A6 | -0.0380216 |
| RPL23 | ribosomal protein L23 | -0.0377963 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0375573 |
| RPS8 | ribosomal protein S8 | -0.0373729 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0368029 |
| RPL37A | ribosomal protein L37a | -0.0366867 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0366688 |
| S100A10 | S100 calcium binding protein A10 | -0.0364054 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0361787 |
| RPLP2 | ribosomal protein, large, P2 | -0.0355838 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0354516 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0354404 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0351206 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0349857 |
| THBD | thrombomodulin | -0.0348171 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0346532 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0346532 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0346123 |
| CALU | calumenin | -0.0338623 |
| HMGA1 | high mobility group AT-hook 1 | -0.0335761 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0334354 |
| CLMP | CXADR-like membrane protein | -0.0332214 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0330874 |
| RPS24 | ribosomal protein S24 | -0.0329381 |
| RPL37 | ribosomal protein L37 | -0.0328894 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0325828 |
| PRRC2C | proline-rich coiled-coil 2C | -0.032308 |
| RPL26 | ribosomal protein L26 | -0.0321666 |
| RPS20 | ribosomal protein S20 | -0.0316325 |
| MTDH | metadherin | -0.0313036 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0312367 |
| FAM107B | family with sequence similarity 107, member B | -0.0310161 |
| RPL8 | ribosomal protein L8 | -0.0308535 |
| RPS13 | ribosomal protein S13 | -0.0308196 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0307921 |
| IER3 | immediate early response 3 | -0.0304077 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0302569 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0298301 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0294238 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0293931 |
| RPL12 | ribosomal protein L12 | -0.0293131 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0292746 |
| RPS27 | ribosomal protein S27 | -0.0290741 |
| RPL11 | ribosomal protein L11 | -0.028602 |
| SDC4 | syndecan 4 | -0.0283058 |
| UBC | ubiquitin C | -0.0283049 |
