| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.111161 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.105479 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0979358 |
| CLTC | clathrin, heavy chain (Hc) | 0.0888195 |
| INTS6 | integrator complex subunit 6 | 0.0864018 |
| CDK12 | cyclin-dependent kinase 12 | 0.0842794 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0823548 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0800882 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0772052 |
| CEP250 | centrosomal protein 250kDa | 0.0746188 |
| FNDC3A | fibronectin type III domain containing 3A | 0.074284 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0639958 |
| MCL1 | myeloid cell leukemia 1 | 0.0634485 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0632841 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0597847 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0595572 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0576826 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0570617 |
| SMYD3 | SET and MYND domain containing 3 | 0.0567664 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0563317 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0543968 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0540075 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.053249 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0516595 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0512479 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0497352 |
| PTK2 | protein tyrosine kinase 2 | 0.0497273 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.049622 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0493414 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0493278 |
| VCL | vinculin | 0.0474834 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0466471 |
| ATXN1 | ataxin 1 | 0.0466106 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0462494 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0462341 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0459717 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0458163 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0453941 |
| VCP | valosin containing protein | 0.0447223 |
| YAP1 | Yes-associated protein 1 | 0.0441117 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0433886 |
| ENAH | enabled homolog (Drosophila) | 0.0429868 |
| SP100 | SP100 nuclear antigen | 0.041824 |
| PARD3 | par-3 family cell polarity regulator | 0.040835 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0404895 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0404154 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0394334 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0392442 |
| SEPTIN9 | septin 9 | 0.0388951 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0380923 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0379711 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0377482 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0366291 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0366181 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0363946 |
| RAD51B | RAD51 paralog B | 0.036032 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0358312 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0357956 |
| ADIPOR2 | adiponectin receptor 2 | 0.0357177 |
| RPL19 | ribosomal protein L19 | 0.0356351 |
| EFNA5 | ephrin-A5 | 0.0354976 |
| KRT86 | keratin 86, type II | 0.035395 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0353827 |
| SBF2 | SET binding factor 2 | 0.035 |
| MED13 | mediator complex subunit 13 | 0.0348682 |
| PLSCR1 | phospholipid scramblase 1 | 0.0342742 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.03388 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0338692 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0336586 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0333693 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0332644 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0332463 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0331321 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0330469 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0330085 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0321207 |
| RCOR1 | REST corepressor 1 | 0.0319487 |
| SRPK2 | SRSF protein kinase 2 | 0.0318415 |
| CDK13 | cyclin-dependent kinase 13 | 0.031473 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0311748 |
| SLFN5 | schlafen family member 5 | 0.0311398 |
| USO1 | USO1 vesicle transport factor | 0.0306191 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0305381 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0303357 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0302963 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0301376 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0300988 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0299715 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0296034 |
| STXBP4 | syntaxin binding protein 4 | 0.0292566 |
| SET | SET nuclear proto-oncogene | 0.0292296 |
| ADAR | adenosine deaminase, RNA-specific | 0.0291559 |
| ASPH | aspartate beta-hydroxylase | 0.0290227 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0290001 |
| DENND1A | DENN/MADD domain containing 1A | 0.0288069 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | 0.0287401 |
| FAM168A | family with sequence similarity 168, member A | 0.0287068 |
| STK4 | serine/threonine kinase 4 | 0.0286497 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0286416 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0285643 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.105891 |
| PTMA | prothymosin, alpha | -0.0758843 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0658747 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0569795 |
| TMSB4X | thymosin beta 4, X-linked | -0.052731 |
| TMSB10 | thymosin beta 10 | -0.0497334 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0469243 |
| RPL23 | ribosomal protein L23 | -0.043481 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0422261 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0419059 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0386985 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0381089 |
| RPL35A | ribosomal protein L35a | -0.0363389 |
| NDRG1 | N-myc downstream regulated 1 | -0.031475 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0313478 |
| LASP1 | LIM and SH3 protein 1 | -0.0310055 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0294827 |
| ACTG1 | actin gamma 1 | -0.0289736 |
| CCND1 | cyclin D1 | -0.0282867 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0281024 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.027479 |
| S100A6 | S100 calcium binding protein A6 | -0.0252359 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0251777 |
| SDC4 | syndecan 4 | -0.0246655 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0244715 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0244525 |
| AHNAK | AHNAK nucleoprotein | -0.0244323 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0237571 |
| RPS6 | ribosomal protein S6 | -0.0234463 |
| KAZN | kazrin, periplakin interacting protein | -0.023268 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0229626 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0222266 |
| FASN | fatty acid synthase | -0.0214855 |
| KLF6 | Kruppel-like factor 6 | -0.0213913 |
| RPL34 | ribosomal protein L34 | -0.0213799 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0207978 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0205763 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0202019 |
| RPS24 | ribosomal protein S24 | -0.0200975 |
| OSMR | oncostatin M receptor | -0.0200812 |
| RPS19 | ribosomal protein S19 | -0.0200206 |
| TMEM123 | transmembrane protein 123 | -0.0199931 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0199409 |
| S100A8 | S100 calcium binding protein A8 | -0.0197594 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0196469 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0191784 |
| S100A9 | S100 calcium binding protein A9 | -0.0190898 |
| FTL | ferritin, light polypeptide | -0.0190406 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0183287 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0182111 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0181972 |
| RESF1 | retroelement silencing factor 1 | -0.0180722 |
| RPL8 | ribosomal protein L8 | -0.01762 |
| IER3 | immediate early response 3 | -0.0173347 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0173127 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0168264 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0166175 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0164302 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0164112 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0161014 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0159782 |
| TXNRD1 | thioredoxin reductase 1 | -0.015937 |
| RPL36 | ribosomal protein L36 | -0.0155638 |
| S100A14 | S100 calcium binding protein A14 | -0.015405 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0152797 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0151071 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.015075 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0150694 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0149522 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0148811 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0148049 |
| S100A10 | S100 calcium binding protein A10 | -0.0147028 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0146922 |
| SQLE | squalene epoxidase | -0.0144901 |
| CCNI | cyclin I | -0.0143235 |
| CD63 | CD63 molecule | -0.0142804 |
| WDR45B | WD repeat domain 45B | -0.0142148 |
| ICAM1 | intercellular adhesion molecule 1 | -0.014158 |
| GNAS | GNAS complex locus | -0.0140918 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.014053 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0139296 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0137831 |
| ARF1 | ADP-ribosylation factor 1 | -0.0137591 |
| SERF2 | small EDRK-rich factor 2 | -0.0137551 |
| MT2A | metallothionein 2A | -0.0136972 |
| INSIG1 | insulin induced gene 1 | -0.0135046 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0133687 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0131805 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0131297 |
| NRCAM | neuronal cell adhesion molecule | -0.0130519 |
| HMGB1 | high mobility group box 1 | -0.0130232 |
| VIM | vimentin | -0.0128916 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0128768 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.012721 |
| CBX3 | chromobox homolog 3 | -0.0126785 |
| TMEM165 | transmembrane protein 165 | -0.0125927 |
| PFN1 | profilin 1 | -0.0124883 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0123798 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0123796 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0123703 |
