| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.178711 |
| COL5A2 | collagen, type V, alpha 2 | 0.163448 |
| ZNF608 | zinc finger protein 608 | 0.12761 |
| VCL | vinculin | 0.125045 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.118081 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.113855 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.108361 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.104232 |
| RIGI | RNA sensor RIG-I | 0.0928294 |
| TOX | thymocyte selection-associated high mobility group box | 0.0886404 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0779697 |
| TENM3 | teneurin transmembrane protein 3 | 0.0767209 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0713471 |
| RAD51B | RAD51 paralog B | 0.0713054 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0710695 |
| BNC2 | basonuclin 2 | 0.0678119 |
| JMJD1C | jumonji domain containing 1C | 0.0666186 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0641209 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0638927 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.062898 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0623566 |
| CDH18 | cadherin 18, type 2 | 0.0613505 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0572568 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0566302 |
| VMP1 | vacuole membrane protein 1 | 0.0493879 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0490355 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0483486 |
| CENPF | centromere protein F, 350/400kDa | 0.0472964 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0467382 |
| RRM2 | ribonucleotide reductase M2 | 0.0458002 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0437705 |
| WLS | wntless Wnt ligand secretion mediator | 0.0436242 |
| YBX1 | Y box binding protein 1 | 0.0435735 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0434736 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0432288 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0423574 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0421914 |
| ASPH | aspartate beta-hydroxylase | 0.0418594 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0418237 |
| MLIP | muscular LMNA-interacting protein | 0.0418055 |
| ENO1 | enolase 1, (alpha) | 0.041418 |
| EXOC4 | exocyst complex component 4 | 0.0407483 |
| NRDC | nardilysin convertase | 0.0404399 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0400783 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0398601 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.039555 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0378961 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0372344 |
| MCL1 | myeloid cell leukemia 1 | 0.036987 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0365864 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0363596 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0355463 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0353569 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0353006 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342808 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0342553 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0338489 |
| BPTF | bromodomain PHD finger transcription factor | 0.0338227 |
| ATG10 | autophagy related 10 | 0.0337526 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0336649 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0335994 |
| SIK3 | SIK family kinase 3 | 0.0334434 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0328245 |
| PCM1 | pericentriolar material 1 | 0.032613 |
| CCDC88A | coiled-coil domain containing 88A | 0.0325164 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0324973 |
| NFIB | nuclear factor I/B | 0.0324422 |
| CENPE | centromere protein E, 312kDa | 0.0319451 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.031661 |
| RPS2 | ribosomal protein S2 | 0.0314529 |
| PMP22 | peripheral myelin protein 22 | 0.0313526 |
| YAP1 | Yes-associated protein 1 | 0.031235 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0311423 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0309694 |
| WWOX | WW domain containing oxidoreductase | 0.0309077 |
| TPM4 | tropomyosin 4 | 0.0305499 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0303255 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0303224 |
| USP34 | ubiquitin specific peptidase 34 | 0.0300573 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0299624 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0293864 |
| CEP250 | centrosomal protein 250kDa | 0.028777 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0285869 |
| ZNF644 | zinc finger protein 644 | 0.028512 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0283937 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0283191 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0282147 |
| FERMT2 | fermitin family member 2 | 0.0281545 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0279541 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0278063 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0277484 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0277186 |
| SETX | senataxin | 0.0276872 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.027612 |
| ADAR | adenosine deaminase, RNA-specific | 0.0275278 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0275232 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0274248 |
| NBEA | neurobeachin | 0.0270788 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0269388 |
| CADM2 | cell adhesion molecule 2 | 0.0267928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.165052 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0694889 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0590366 |
| RPS6 | ribosomal protein S6 | -0.0539239 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0532698 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.052121 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.050808 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0487997 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0481749 |
| PTMA | prothymosin, alpha | -0.0461536 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0456008 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0454495 |
| TMSB10 | thymosin beta 10 | -0.044404 |
| EFNA5 | ephrin-A5 | -0.0444035 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0426971 |
| RPL4 | ribosomal protein L4 | -0.0421092 |
| RPS24 | ribosomal protein S24 | -0.04006 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0389679 |
| FMNL2 | formin-like 2 | -0.0381841 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0363293 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.035608 |
| RPS21 | ribosomal protein S21 | -0.0350138 |
| RPL35A | ribosomal protein L35a | -0.0348192 |
| RPL34 | ribosomal protein L34 | -0.0338482 |
| NGLY1 | N-glycanase 1 | -0.0332962 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0311969 |
| ZNF544 | zinc finger protein 544 | -0.0310159 |
| WDR45B | WD repeat domain 45B | -0.0309436 |
| MAP4 | microtubule-associated protein 4 | -0.0299353 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0296379 |
| RPL23 | ribosomal protein L23 | -0.0292081 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.029008 |
| RPL11 | ribosomal protein L11 | -0.0288079 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0287515 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0262268 |
| ACTG1 | actin gamma 1 | -0.025585 |
| KIAA1958 | KIAA1958 | -0.0253021 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.024846 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0248317 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0246987 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0237633 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0234604 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0231606 |
| INSIG2 | insulin induced gene 2 | -0.0230873 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0230336 |
| RPS19 | ribosomal protein S19 | -0.0226263 |
| RPL6 | ribosomal protein L6 | -0.0225672 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0224884 |
| FBL | fibrillarin | -0.0224856 |
| RPL37A | ribosomal protein L37a | -0.0224324 |
| ATRN | attractin | -0.0215581 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.021436 |
| ZFP64 | ZFP64 zinc finger protein | -0.0214089 |
| CAVIN1 | caveolae associated protein 1 | -0.020704 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0204916 |
| EMP1 | epithelial membrane protein 1 | -0.0204374 |
| RPL26 | ribosomal protein L26 | -0.0204015 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0203142 |
| RPL31 | ribosomal protein L31 | -0.0203126 |
| HMGA1 | high mobility group AT-hook 1 | -0.0202178 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0201829 |
| RPS11 | ribosomal protein S11 | -0.0200184 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0197441 |
| RPS13 | ribosomal protein S13 | -0.0197226 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0196672 |
| FOXK2 | forkhead box K2 | -0.0196381 |
| TPD52 | tumor protein D52 | -0.0195458 |
| TENM2 | teneurin transmembrane protein 2 | -0.019457 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.019403 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0193374 |
| RPL14 | ribosomal protein L14 | -0.0192643 |
| FASN | fatty acid synthase | -0.0189793 |
| RPL32 | ribosomal protein L32 | -0.0189352 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0187127 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0186828 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0185609 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0184796 |
| RPS17 | ribosomal protein S17 | -0.0183021 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0182402 |
| RPS5 | ribosomal protein S5 | -0.0181464 |
| RNF145 | ring finger protein 145 | -0.0180648 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0178993 |
| FOXO3 | forkhead box O3 | -0.0178683 |
| RPL19 | ribosomal protein L19 | -0.0176291 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0174408 |
| RPL36 | ribosomal protein L36 | -0.0174038 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0171797 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0171298 |
| ZNF217 | zinc finger protein 217 | -0.0170318 |
| RNF130 | ring finger protein 130 | -0.0169483 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | -0.0169266 |
| GOLGA4 | golgin A4 | -0.0169118 |
| RPS28 | ribosomal protein S28 | -0.0168874 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0168674 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.016815 |
| RPS8 | ribosomal protein S8 | -0.0166492 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0166116 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0166041 |
| ARF1 | ADP-ribosylation factor 1 | -0.0165289 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0165249 |
