| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.101698 |
| GPC6 | glypican 6 | 0.0970827 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0863078 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0847108 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0804294 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0791293 |
| FMN1 | formin 1 | 0.0718098 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0715047 |
| FN1 | fibronectin 1 | 0.0704456 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0665153 |
| ATXN1 | ataxin 1 | 0.0625778 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0610302 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.058573 |
| EXOC4 | exocyst complex component 4 | 0.05482 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0537743 |
| TLE4 | transducin-like enhancer of split 4 | 0.0519129 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0512344 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0512331 |
| ACTN1 | actinin, alpha 1 | 0.0486167 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0476648 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0465325 |
| DST | dystonin | 0.0465222 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0448786 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0441488 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0438189 |
| PLAT | plasminogen activator, tissue | 0.0434335 |
| ZYX | zyxin | 0.0428567 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0420747 |
| MCL1 | myeloid cell leukemia 1 | 0.0406149 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0400848 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0395016 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0394803 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0391106 |
| FRMD4A | FERM domain containing 4A | 0.0389541 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0384193 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0382481 |
| RAD51B | RAD51 paralog B | 0.038119 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0378764 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.036883 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.034682 |
| TPM4 | tropomyosin 4 | 0.0346497 |
| INTS6 | integrator complex subunit 6 | 0.034385 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0343072 |
| RCAN1 | regulator of calcineurin 1 | 0.0341544 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0340261 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0335661 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0329593 |
| VIM | vimentin | 0.032396 |
| CLIC4 | chloride intracellular channel 4 | 0.0323854 |
| MYO1E | myosin IE | 0.0320575 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0313981 |
| BRD2 | bromodomain containing 2 | 0.029969 |
| SQSTM1 | sequestosome 1 | 0.0294816 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0293756 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.028904 |
| ANK2 | ankyrin 2, neuronal | 0.0285041 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0284425 |
| SFTPA2 | surfactant protein A2 | 0.0282349 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278422 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0276671 |
| SMYD3 | SET and MYND domain containing 3 | 0.0273137 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0272445 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0271741 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0271407 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.026734 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.026725 |
| SHISA5 | shisa family member 5 | 0.0266514 |
| VCL | vinculin | 0.0265842 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0262509 |
| POTEF | POTE ankyrin domain family, member F | 0.0261217 |
| UTRN | utrophin | 0.0257531 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0254944 |
| SETBP1 | SET binding protein 1 | 0.0254208 |
| ADM | adrenomedullin | 0.0249691 |
| LDHA | lactate dehydrogenase A | 0.0245388 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0244638 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0243169 |
| PAX3 | paired box 3 | 0.0240916 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0237831 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0237826 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0237696 |
| SYNM | synemin, intermediate filament protein | 0.0237328 |
| MITF | microphthalmia-associated transcription factor | 0.0236021 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0235513 |
| EXOC6B | exocyst complex component 6B | 0.0234532 |
| GAS7 | growth arrest-specific 7 | 0.0232635 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0232591 |
| CYTH3 | cytohesin 3 | 0.0231274 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0230726 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0227394 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.022709 |
| TPR | translocated promoter region, nuclear basket protein | 0.022406 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0223578 |
| MACROD2 | MACRO domain containing 2 | 0.0221913 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.022006 |
| PI15 | peptidase inhibitor 15 | 0.0219801 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0219462 |
| FERMT2 | fermitin family member 2 | 0.0219349 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0219312 |
| BPTF | bromodomain PHD finger transcription factor | 0.02177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.111292 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109394 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0965179 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0936661 |
| VGF | VGF nerve growth factor inducible | -0.0924642 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0885574 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0883864 |
| TMSB10 | thymosin beta 10 | -0.0736943 |
| CENPF | centromere protein F, 350/400kDa | -0.0722941 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0722261 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0717954 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0704489 |
| ZNF292 | zinc finger protein 292 | -0.069842 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0690184 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0685753 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0664923 |
| NPC1 | Niemann-Pick disease, type C1 | -0.063538 |
| CDC73 | cell division cycle 73 | -0.0611308 |
| GOLGA4 | golgin A4 | -0.0572581 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0570533 |
| NDRG1 | N-myc downstream regulated 1 | -0.0558945 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0549073 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0545252 |
| WDR45B | WD repeat domain 45B | -0.0535932 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0524801 |
| TMEM123 | transmembrane protein 123 | -0.0524452 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0524388 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0522659 |
| RUNX1 | runt-related transcription factor 1 | -0.0521743 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0516111 |
| PGK1 | phosphoglycerate kinase 1 | -0.0511444 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0502633 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0498936 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0496695 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0490128 |
| NAV2 | neuron navigator 2 | -0.0471777 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0436832 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.042253 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0413915 |
| NBAS | neuroblastoma amplified sequence | -0.0401027 |
| SRPK2 | SRSF protein kinase 2 | -0.0390932 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0389528 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0386878 |
| PHF21A | PHD finger protein 21A | -0.0386081 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0384685 |
| MTPN | myotrophin | -0.0377684 |
| TAGLN2 | transgelin 2 | -0.0373965 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0370907 |
| SCFD2 | sec1 family domain containing 2 | -0.0367756 |
| POM121 | POM121 transmembrane nucleoporin | -0.0366844 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0365325 |
| TPD52 | tumor protein D52 | -0.0353573 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0353215 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.035291 |
| CDK14 | cyclin-dependent kinase 14 | -0.0346734 |
| FOXJ3 | forkhead box J3 | -0.0342007 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0331862 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0331715 |
| RHEB | Ras homolog enriched in brain | -0.0326987 |
| GTF2I | general transcription factor IIi | -0.0326858 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0323092 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0319384 |
| MT1X | metallothionein 1X | -0.031866 |
| HELZ | helicase with zinc finger | -0.0318072 |
| GNAS | GNAS complex locus | -0.0317944 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0316706 |
| RBM33 | RNA binding motif protein 33 | -0.0315503 |
| COG5 | component of oligomeric golgi complex 5 | -0.0313431 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0313072 |
| AHNAK | AHNAK nucleoprotein | -0.0309184 |
| EHBP1 | EH domain binding protein 1 | -0.030567 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0303496 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0298779 |
| MKI67 | marker of proliferation Ki-67 | -0.029708 |
| CTSD | cathepsin D | -0.0296605 |
| RNF145 | ring finger protein 145 | -0.029608 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0290731 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0288987 |
| CALD1 | caldesmon 1 | -0.0287973 |
| NAV3 | neuron navigator 3 | -0.0287262 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0276037 |
| OSMR | oncostatin M receptor | -0.0274851 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0272518 |
| AHR | aryl hydrocarbon receptor | -0.026992 |
| IER3 | immediate early response 3 | -0.0269634 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0269012 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0268773 |
| TNPO3 | transportin 3 | -0.0265306 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0263566 |
| CALU | calumenin | -0.0263491 |
| SSH1 | slingshot protein phosphatase 1 | -0.0263407 |
| INSIG1 | insulin induced gene 1 | -0.0262398 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0260896 |
| INSIG2 | insulin induced gene 2 | -0.0259741 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0258984 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | -0.0258464 |
| MEF2A | myocyte enhancer factor 2A | -0.0258243 |
| HMCN1 | hemicentin 1 | -0.025809 |
| SBF2 | SET binding factor 2 | -0.0257903 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0256718 |
