| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE4 | transducin-like enhancer of split 4 | 0.113465 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0939062 |
| VCL | vinculin | 0.0739811 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0580565 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0554594 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0542447 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0502488 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0499922 |
| PLPP1 | phospholipid phosphatase 1 | 0.0491049 |
| STK38L | serine/threonine kinase 38 like | 0.047795 |
| LPIN1 | lipin 1 | 0.0465705 |
| SYT1 | synaptotagmin I | 0.0463438 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0451118 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0450894 |
| MRTFA | myocardin related transcription factor A | 0.0442718 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0435318 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0402541 |
| SIK2 | salt-inducible kinase 2 | 0.0395049 |
| FAM107B | family with sequence similarity 107, member B | 0.0389729 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0388097 |
| CADM2 | cell adhesion molecule 2 | 0.0383504 |
| BPTF | bromodomain PHD finger transcription factor | 0.0378523 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0375653 |
| GAB2 | GRB2-associated binding protein 2 | 0.037072 |
| PDE10A | phosphodiesterase 10A | 0.036503 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0364958 |
| KLHL13 | kelch-like family member 13 | 0.0363462 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0361835 |
| SYNPO2 | synaptopodin 2 | 0.0347463 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0340987 |
| SPOP | speckle-type POZ protein | 0.0328713 |
| TRIB2 | tribbles pseudokinase 2 | 0.0328351 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0327648 |
| INTS6 | integrator complex subunit 6 | 0.0325156 |
| RIGI | RNA sensor RIG-I | 0.0322718 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0321405 |
| FHL2 | four and a half LIM domains 2 | 0.0318712 |
| FERMT2 | fermitin family member 2 | 0.0316433 |
| GLCCI1 | glucocorticoid induced 1 | 0.0314718 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0314625 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0308496 |
| AMOTL1 | angiomotin like 1 | 0.0296015 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.029193 |
| CDK6 | cyclin-dependent kinase 6 | 0.0285006 |
| SEPTIN9 | septin 9 | 0.0284654 |
| TCF12 | transcription factor 12 | 0.0283386 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0281123 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0280584 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0278028 |
| MED13 | mediator complex subunit 13 | 0.0276334 |
| ZNF804A | zinc finger protein 804A | 0.0273902 |
| MAP1B | microtubule-associated protein 1B | 0.0269049 |
| RPS2 | ribosomal protein S2 | 0.0268743 |
| VMP1 | vacuole membrane protein 1 | 0.0266236 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0264638 |
| PCDH17 | protocadherin 17 | 0.0258608 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0256659 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0253402 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0253359 |
| DUSP10 | dual specificity phosphatase 10 | 0.0248157 |
| CENPF | centromere protein F, 350/400kDa | 0.0247277 |
| IRS1 | insulin receptor substrate 1 | 0.02468 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0245987 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0245667 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0243761 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0243604 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0242726 |
| MYO6 | myosin VI | 0.0242021 |
| MEIS2 | Meis homeobox 2 | 0.0240099 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0232294 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0226015 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0225787 |
| CPNE8 | copine VIII | 0.0225654 |
| TENM4 | teneurin transmembrane protein 4 | 0.0225099 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.0224781 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0224643 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0223147 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0221038 |
| TPM1 | tropomyosin 1 (alpha) | 0.0220647 |
| ETNK1 | ethanolamine kinase 1 | 0.0218657 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0212742 |
| FOXO3 | forkhead box O3 | 0.0212002 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0211868 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0211058 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.021081 |
| JMJD1C | jumonji domain containing 1C | 0.0208121 |
| PSPC1 | paraspeckle component 1 | 0.0205439 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0204511 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.0204212 |
| THBS1 | thrombospondin 1 | 0.0204187 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0203021 |
| PALLD | palladin, cytoskeletal associated protein | 0.0201971 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0201046 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0200413 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0196537 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0195407 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0194448 |
| PCBP2 | poly(rC) binding protein 2 | 0.0193095 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0188153 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0187889 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.368856 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.104308 |
| PTMA | prothymosin, alpha | -0.103224 |
| VIM | vimentin | -0.0948096 |
| RPL23 | ribosomal protein L23 | -0.0885864 |
| LSAMP | limbic system-associated membrane protein | -0.0821238 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0791994 |
| NRG1 | neuregulin 1 | -0.0723888 |
| COL1A1 | collagen, type I, alpha 1 | -0.0691532 |
| RPL35A | ribosomal protein L35a | -0.0686325 |
| RPS6 | ribosomal protein S6 | -0.065182 |
| COL3A1 | collagen, type III, alpha 1 | -0.0623835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0620903 |
| RPL34 | ribosomal protein L34 | -0.0612198 |
| FTL | ferritin, light polypeptide | -0.0608579 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0603841 |
| FRMD4A | FERM domain containing 4A | -0.0566755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0551926 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0547992 |
| NDRG1 | N-myc downstream regulated 1 | -0.0541198 |
| RPS19 | ribosomal protein S19 | -0.0498627 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0489391 |
| RPLP1 | ribosomal protein, large, P1 | -0.0462087 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0446479 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.043324 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0426916 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0425761 |
| TMSB10 | thymosin beta 10 | -0.0424441 |
| H3-3B | H3.3 histone B | -0.0421917 |
| FMN1 | formin 1 | -0.0414634 |
| GOLGA4 | golgin A4 | -0.0411607 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0402341 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0390592 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0388661 |
| GPC5 | glypican 5 | -0.0384976 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0367936 |
| HIP1 | huntingtin interacting protein 1 | -0.0363324 |
| SCG2 | secretogranin II | -0.0361395 |
| RPS24 | ribosomal protein S24 | -0.0358479 |
| RPL31 | ribosomal protein L31 | -0.0353931 |
| HELZ | helicase with zinc finger | -0.035291 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0352789 |
| RPL37A | ribosomal protein L37a | -0.0350407 |
| NREP | neuronal regeneration related protein | -0.0348528 |
| RPS14 | ribosomal protein S14 | -0.034398 |
| DTNA | dystrobrevin, alpha | -0.0338043 |
| RGS5 | regulator of G-protein signaling 5 | -0.032541 |
| RPS20 | ribosomal protein S20 | -0.032033 |
| MATR3 | matrin 3 | -0.0317405 |
| RPL4 | ribosomal protein L4 | -0.0316965 |
| ZNF292 | zinc finger protein 292 | -0.0312519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0307482 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0307457 |
| WDR45B | WD repeat domain 45B | -0.0307041 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0304703 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0297459 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0294442 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0290964 |
| RPL38 | ribosomal protein L38 | -0.028891 |
| CRH | corticotropin releasing hormone | -0.0288747 |
| DIAPH2 | diaphanous-related formin 2 | -0.0287343 |
| FAM13A | family with sequence similarity 13, member A | -0.0287055 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0285378 |
| CANX | calnexin | -0.028504 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.028077 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0278553 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0274905 |
| RPL19 | ribosomal protein L19 | -0.027219 |
| ACTG1 | actin gamma 1 | -0.0270791 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0270591 |
| GNAS | GNAS complex locus | -0.026837 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0267898 |
| RPS5 | ribosomal protein S5 | -0.0266929 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264139 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0263783 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0262092 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0259976 |
| FAM162A | family with sequence similarity 162, member A | -0.02573 |
| VEGFA | vascular endothelial growth factor A | -0.0255222 |
| ATF4 | activating transcription factor 4 | -0.0252396 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0250877 |
| B2M | beta-2-microglobulin | -0.0249127 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0248743 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0248291 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0248061 |
| ZNF124 | zinc finger protein 124 | -0.0247872 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0246219 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0244783 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0243846 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0242949 |
| RPL11 | ribosomal protein L11 | -0.023883 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0236716 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0235472 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0234688 |
| MSI2 | musashi RNA-binding protein 2 | -0.0233274 |
| CALR | calreticulin | -0.0232707 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0229577 |
| CALD1 | caldesmon 1 | -0.0228647 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.022741 |
| RPS13 | ribosomal protein S13 | -0.0226029 |
