| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0786616 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0744671 |
| NLGN1 | neuroligin 1 | 0.0646842 |
| ASPH | aspartate beta-hydroxylase | 0.0514253 |
| CD44 | CD44 molecule (Indian blood group) | 0.0457364 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.042245 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0417943 |
| LDHA | lactate dehydrogenase A | 0.0409197 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0389368 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0384385 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0373027 |
| MYLK | myosin light chain kinase | 0.0370567 |
| VCL | vinculin | 0.0366446 |
| UBC | ubiquitin C | 0.0347296 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0341642 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0336402 |
| PCBP2 | poly(rC) binding protein 2 | 0.0335685 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0327821 |
| CENPF | centromere protein F, 350/400kDa | 0.0318359 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0300149 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0300045 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0299896 |
| ENO1 | enolase 1, (alpha) | 0.0296356 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0292463 |
| WLS | wntless Wnt ligand secretion mediator | 0.0289257 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0286785 |
| FLNA | filamin A, alpha | 0.0286667 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0282831 |
| TPM4 | tropomyosin 4 | 0.0279792 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0273944 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0271335 |
| TPM3 | tropomyosin 3 | 0.0271087 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0270575 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0267313 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02666 |
| RIGI | RNA sensor RIG-I | 0.0263289 |
| ANXA2 | annexin A2 | 0.0261941 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0259945 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0258329 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0252038 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0247458 |
| MCL1 | myeloid cell leukemia 1 | 0.0241382 |
| CLIC4 | chloride intracellular channel 4 | 0.0237764 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0226141 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0225696 |
| CEP128 | centrosomal protein 128kDa | 0.0224581 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0223743 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0221033 |
| SETBP1 | SET binding protein 1 | 0.0218053 |
| MYO10 | myosin X | 0.0216243 |
| SFPQ | splicing factor proline/glutamine-rich | 0.021585 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0211421 |
| HOMER1 | homer scaffolding protein 1 | 0.0210564 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0210256 |
| APP | amyloid beta (A4) precursor protein | 0.0205032 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0204205 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0200709 |
| GANAB | glucosidase, alpha; neutral AB | 0.019921 |
| PDLIM5 | PDZ and LIM domain 5 | 0.019842 |
| CALN1 | calneuron 1 | 0.0195946 |
| FHL2 | four and a half LIM domains 2 | 0.0195473 |
| SATB2 | SATB homeobox 2 | 0.0194389 |
| PTK2 | protein tyrosine kinase 2 | 0.0193348 |
| MSN | moesin | 0.0191872 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0190689 |
| NAV2 | neuron navigator 2 | 0.0190126 |
| PCDH7 | protocadherin 7 | 0.0188933 |
| GLIS3 | GLIS family zinc finger 3 | 0.018529 |
| WWOX | WW domain containing oxidoreductase | 0.0183497 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0181464 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0181033 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0179459 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0178169 |
| FRYL | FRY-like | 0.0176767 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0173941 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0170773 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0168481 |
| FGF13 | fibroblast growth factor 13 | 0.0164848 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0163201 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0162741 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0162544 |
| CANX | calnexin | 0.0161684 |
| ACTN4 | actinin, alpha 4 | 0.0161649 |
| YEATS2 | YEATS domain containing 2 | 0.0161384 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0161203 |
| FLNB | filamin B, beta | 0.0159248 |
| DEK | DEK proto-oncogene | 0.015772 |
| CALU | calumenin | 0.0156763 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0156042 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0156012 |
| SQSTM1 | sequestosome 1 | 0.0155506 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0154802 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0154524 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0152086 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0152069 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0151944 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0151887 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0151459 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0149822 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.014901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156587 |
| NDRG1 | N-myc downstream regulated 1 | -0.154536 |
| TMSB10 | thymosin beta 10 | -0.151287 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.132991 |
| MT2A | metallothionein 2A | -0.117111 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.084813 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0774637 |
| PTMA | prothymosin, alpha | -0.0698286 |
| LOX | lysyl oxidase | -0.0692711 |
| FTL | ferritin, light polypeptide | -0.0692578 |
| GOLGA4 | golgin A4 | -0.0692066 |
| RPL35A | ribosomal protein L35a | -0.0571668 |
| RPS6 | ribosomal protein S6 | -0.056558 |
| INHBA | inhibin, beta A | -0.0563523 |
| GNAS | GNAS complex locus | -0.0537706 |
| TNS3 | tensin 3 | -0.0532247 |
| SBF2 | SET binding factor 2 | -0.0471954 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0454887 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0441435 |
| RRBP1 | ribosome binding protein 1 | -0.0438044 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0436138 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0413771 |
| AHNAK | AHNAK nucleoprotein | -0.041119 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.040505 |
| CALD1 | caldesmon 1 | -0.0403701 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0401134 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.040006 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0398252 |
| IGF2 | insulin-like growth factor 2 | -0.0396625 |
| SEC24D | SEC24 family member D | -0.0393024 |
| HDLBP | high density lipoprotein binding protein | -0.0384358 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0377293 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0372277 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0368012 |
| COG5 | component of oligomeric golgi complex 5 | -0.0363562 |
| GOLGB1 | golgin B1 | -0.0356918 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0356267 |
| TMSB4X | thymosin beta 4, X-linked | -0.0355668 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346489 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0344938 |
| GPR173 | G protein-coupled receptor 173 | -0.0341961 |
| OSMR | oncostatin M receptor | -0.034166 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0337077 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0333895 |
| CLINT1 | clathrin interactor 1 | -0.03318 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0330997 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0330954 |
| CADM1 | cell adhesion molecule 1 | -0.0329529 |
| RPS19 | ribosomal protein S19 | -0.0325595 |
| MT1X | metallothionein 1X | -0.0323763 |
| ATF4 | activating transcription factor 4 | -0.0322178 |
| ASTN2 | astrotactin 2 | -0.0318163 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0310301 |
| RPLP2 | ribosomal protein, large, P2 | -0.030569 |
| RPS13 | ribosomal protein S13 | -0.0300181 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0299725 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0298895 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0296231 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0293167 |
| HLA-B | major histocompatibility complex, class I, B | -0.0292329 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0290262 |
| STC1 | stanniocalcin 1 | -0.0288204 |
| RPS16 | ribosomal protein S16 | -0.0286614 |
| EGFR | epidermal growth factor receptor | -0.028525 |
| RPS24 | ribosomal protein S24 | -0.0284497 |
| RPL28 | ribosomal protein L28 | -0.0280949 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.028059 |
| HMGA1 | high mobility group AT-hook 1 | -0.02788 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.027664 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0273825 |
| FN1 | fibronectin 1 | -0.0270632 |
| MAP1B | microtubule-associated protein 1B | -0.0270356 |
| SERF2 | small EDRK-rich factor 2 | -0.0267254 |
| RPL12 | ribosomal protein L12 | -0.0266416 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.026599 |
| SRP54 | signal recognition particle 54kDa | -0.0264278 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0262479 |
| RSF1 | remodeling and spacing factor 1 | -0.0261734 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0261633 |
| MKI67 | marker of proliferation Ki-67 | -0.0261229 |
| ZNF432 | zinc finger protein 432 | -0.0259411 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0258071 |
| SEPTIN2 | septin 2 | -0.0252791 |
| MMP12 | matrix metallopeptidase 12 | -0.0251788 |
| CAVIN1 | caveolae associated protein 1 | -0.0251703 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0249666 |
| HM13 | histocompatibility (minor) 13 | -0.0247456 |
| WDR45B | WD repeat domain 45B | -0.0247419 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0245549 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0244494 |
| SEC61G | Sec61 gamma subunit | -0.0244415 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0243022 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0242983 |
| RPL26 | ribosomal protein L26 | -0.0241204 |
| SEC24A | SEC24 family member A | -0.0240618 |
| MAP4 | microtubule-associated protein 4 | -0.0240383 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0240195 |
| RPLP1 | ribosomal protein, large, P1 | -0.0238237 |
| RNF216 | ring finger protein 216 | -0.0236944 |
| CDK6 | cyclin-dependent kinase 6 | -0.0236501 |
