| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.13307 |
| ASPH | aspartate beta-hydroxylase | 0.132241 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.100521 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0991142 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.093316 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0891219 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0884743 |
| SVIL | supervillin | 0.0867154 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0827063 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0785458 |
| MACROD2 | MACRO domain containing 2 | 0.0757375 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.075439 |
| TPM4 | tropomyosin 4 | 0.0724795 |
| VCL | vinculin | 0.0708079 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0664296 |
| LAMC2 | laminin, gamma 2 | 0.0653908 |
| HMGA2 | high mobility group AT-hook 2 | 0.0627456 |
| PAX8 | paired box 8 | 0.0627247 |
| WWC1 | WW and C2 domain containing 1 | 0.0626496 |
| CD44 | CD44 molecule (Indian blood group) | 0.0620953 |
| FLNA | filamin A, alpha | 0.0594772 |
| RAD51B | RAD51 paralog B | 0.0588554 |
| ITGB8 | integrin, beta 8 | 0.0588292 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0533972 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.053209 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0524216 |
| WWOX | WW domain containing oxidoreductase | 0.0515789 |
| ANXA3 | annexin A3 | 0.0510474 |
| PRELID2 | PRELI domain containing 2 | 0.0504897 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0499541 |
| ITGA6 | integrin, alpha 6 | 0.0491033 |
| ERBIN | erbb2 interacting protein | 0.0478071 |
| SEPTIN9 | septin 9 | 0.0457243 |
| ATXN1 | ataxin 1 | 0.0454532 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0442841 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0442528 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0438665 |
| LAMA4 | laminin, alpha 4 | 0.0436213 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0433266 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0426912 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0426356 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0411174 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0406976 |
| MT2A | metallothionein 2A | 0.0403557 |
| SMAD3 | SMAD family member 3 | 0.0399468 |
| ECT2 | epithelial cell transforming 2 | 0.039588 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0393371 |
| EGFR | epidermal growth factor receptor | 0.0392153 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0389594 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0388083 |
| AXL | AXL receptor tyrosine kinase | 0.0385608 |
| SMYD3 | SET and MYND domain containing 3 | 0.0385564 |
| DIAPH3 | diaphanous-related formin 3 | 0.0385171 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0383994 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0380393 |
| ACTG1 | actin gamma 1 | 0.0374773 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0374705 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0365861 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0365684 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0364008 |
| INTS6 | integrator complex subunit 6 | 0.0363233 |
| MKI67 | marker of proliferation Ki-67 | 0.0358897 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0358664 |
| ANXA2 | annexin A2 | 0.0358299 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0357321 |
| AEBP2 | AE binding protein 2 | 0.03567 |
| EZR | ezrin | 0.0353851 |
| ACTN4 | actinin, alpha 4 | 0.0353213 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0351843 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0351787 |
| FHIT | fragile histidine triad | 0.0351484 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0350328 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0343866 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0343604 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0337512 |
| CEP128 | centrosomal protein 128kDa | 0.033706 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0336405 |
| SSH2 | slingshot protein phosphatase 2 | 0.0330718 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.03287 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | 0.0328554 |
| MMS22L | MMS22-like, DNA repair protein | 0.0327172 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0324935 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0322714 |
| POTEF | POTE ankyrin domain family, member F | 0.0317657 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0314678 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.031092 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0310335 |
| ENO1 | enolase 1, (alpha) | 0.0309823 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0307425 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0305476 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0302538 |
| ANLN | anillin, actin binding protein | 0.0299735 |
| RUNX1 | runt-related transcription factor 1 | 0.0297161 |
| DIAPH1 | diaphanous-related formin 1 | 0.029647 |
| PCNX4 | pecanex 4 | 0.0294278 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.029406 |
| BPTF | bromodomain PHD finger transcription factor | 0.0293559 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0292186 |
| UTRN | utrophin | 0.0289833 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0287415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124225 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0797181 |
| RPS6 | ribosomal protein S6 | -0.0723573 |
| GOLGA4 | golgin A4 | -0.062397 |
| TMSB4X | thymosin beta 4, X-linked | -0.0547055 |
| RPL23 | ribosomal protein L23 | -0.046012 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0442834 |
| MATR3 | matrin 3 | -0.0434369 |
| ZNF292 | zinc finger protein 292 | -0.0423043 |
| NDRG1 | N-myc downstream regulated 1 | -0.0342177 |
| SEC24D | SEC24 family member D | -0.0336428 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0311537 |
| ANKRD10 | ankyrin repeat domain 10 | -0.03089 |
| RPL19 | ribosomal protein L19 | -0.0305849 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0301934 |
| RPS19 | ribosomal protein S19 | -0.0296384 |
| RPL26 | ribosomal protein L26 | -0.0295754 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0290889 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0284119 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0283561 |
| RPL35 | ribosomal protein L35 | -0.0278849 |
| CLINT1 | clathrin interactor 1 | -0.0277833 |
| PTMA | prothymosin, alpha | -0.025962 |
| RPL13A | ribosomal protein L13a | -0.0259046 |
| RPS27 | ribosomal protein S27 | -0.0258139 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0247928 |
| RPL34 | ribosomal protein L34 | -0.0246486 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0236923 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0233151 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0233079 |
| RPL32 | ribosomal protein L32 | -0.0229207 |
| HDLBP | high density lipoprotein binding protein | -0.0224328 |
| RPS21 | ribosomal protein S21 | -0.0222875 |
| CALR | calreticulin | -0.0221383 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0220688 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0216076 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0215667 |
| RPLP2 | ribosomal protein, large, P2 | -0.0215249 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0214882 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0210538 |
| B2M | beta-2-microglobulin | -0.0207832 |
| USP3 | ubiquitin specific peptidase 3 | -0.0203154 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0202539 |
| RPL4 | ribosomal protein L4 | -0.0193698 |
| APP | amyloid beta (A4) precursor protein | -0.0191499 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0187108 |
| RPS23 | ribosomal protein S23 | -0.0184543 |
| H1-0 | H1.0 linker histone | -0.018439 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0182958 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0179907 |
| RNF145 | ring finger protein 145 | -0.0177665 |
| CANX | calnexin | -0.0175531 |
| RPL3 | ribosomal protein L3 | -0.0175401 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0172638 |
| SBF2 | SET binding factor 2 | -0.0171319 |
| RPS8 | ribosomal protein S8 | -0.0171236 |
| NOP53 | NOP53 ribosome biogenesis factor | -0.016924 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0168782 |
| RPL14 | ribosomal protein L14 | -0.0167393 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0163483 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.016321 |
| RPL8 | ribosomal protein L8 | -0.0162128 |
| FOXJ3 | forkhead box J3 | -0.0161733 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0155895 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0153639 |
| RPL18 | ribosomal protein L18 | -0.0153612 |
| CFDP1 | craniofacial development protein 1 | -0.0152812 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0152647 |
| RPL12 | ribosomal protein L12 | -0.0151779 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0151469 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0151243 |
| RPL28 | ribosomal protein L28 | -0.0150813 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0149364 |
| COG5 | component of oligomeric golgi complex 5 | -0.0149282 |
| HYOU1 | hypoxia up-regulated 1 | -0.0148416 |
| RPL36 | ribosomal protein L36 | -0.0148097 |
| DNAJC25 | DnaJ (Hsp40) homolog, subfamily C , member 25 | -0.0147197 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0147064 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0146792 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0145215 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0144821 |
| RLF | rearranged L-myc fusion | -0.0144803 |
| TRAM1 | translocation associated membrane protein 1 | -0.0141815 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0140235 |
| RRBP1 | ribosome binding protein 1 | -0.0139422 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0137613 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0137323 |
| WDR45B | WD repeat domain 45B | -0.013616 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0135847 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0134423 |
| RPS13 | ribosomal protein S13 | -0.0132342 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0132308 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0132169 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0131636 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0128571 |
| GOLGA2 | golgin A2 | -0.0127799 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0124394 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0123687 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0122769 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0122446 |
