| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.110156 |
| FAT1 | FAT atypical cadherin 1 | 0.0890174 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0812258 |
| SMAD3 | SMAD family member 3 | 0.0782258 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0771071 |
| CTBP2 | C-terminal binding protein 2 | 0.0723219 |
| LMO7 | LIM domain 7 | 0.0695562 |
| ACTN4 | actinin, alpha 4 | 0.0679448 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0659313 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0632605 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0606562 |
| NTN4 | netrin 4 | 0.060363 |
| PLK2 | polo-like kinase 2 | 0.0602999 |
| BCL2L1 | BCL2-like 1 | 0.0598085 |
| VCL | vinculin | 0.0579161 |
| STK24 | serine/threonine kinase 24 | 0.0576383 |
| INTS6 | integrator complex subunit 6 | 0.0522148 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0510543 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0492657 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0488326 |
| KRT20 | keratin 20, type I | 0.0476959 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0464633 |
| CCNYL1 | cyclin Y-like 1 | 0.0456323 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0437093 |
| TUFT1 | tuftelin 1 | 0.0436388 |
| ANXA11 | annexin A11 | 0.0435868 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0416188 |
| PCBP2 | poly(rC) binding protein 2 | 0.0415047 |
| MCL1 | myeloid cell leukemia 1 | 0.0406615 |
| EPS8L1 | EPS8-like 1 | 0.0394401 |
| UTRN | utrophin | 0.0392811 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0389974 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0385674 |
| UBC | ubiquitin C | 0.0378457 |
| PDZD8 | PDZ domain containing 8 | 0.0374922 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0372888 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.037268 |
| PPL | periplakin | 0.0372408 |
| TPM3 | tropomyosin 3 | 0.0369168 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0365008 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0364377 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.036429 |
| ECT2 | epithelial cell transforming 2 | 0.0363943 |
| MSN | moesin | 0.0358076 |
| FOXO1 | forkhead box O1 | 0.0354064 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0346902 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0345344 |
| AREG | amphiregulin | 0.0343578 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0341421 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0338882 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334514 |
| CENPF | centromere protein F, 350/400kDa | 0.0333754 |
| MYO1E | myosin IE | 0.0326955 |
| SGMS2 | sphingomyelin synthase 2 | 0.0322167 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0321664 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0315019 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0311515 |
| SFPQ | splicing factor proline/glutamine-rich | 0.031007 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0306819 |
| SMYD3 | SET and MYND domain containing 3 | 0.0300875 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0293954 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0293445 |
| KRT18 | keratin 18, type I | 0.0292314 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0290126 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0288008 |
| RPS27A | ribosomal protein S27a | 0.0283692 |
| EMP1 | epithelial membrane protein 1 | 0.0282368 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0279383 |
| DUSP16 | dual specificity phosphatase 16 | 0.027804 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0277052 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0276892 |
| DIAPH1 | diaphanous-related formin 1 | 0.0276858 |
| PDE10A | phosphodiesterase 10A | 0.0276712 |
| MYEOV | myeloma overexpressed | 0.0276608 |
| FLNA | filamin A, alpha | 0.0272483 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0271318 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0271163 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0262233 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0258609 |
| SEPTIN9 | septin 9 | 0.0256941 |
| PRR5L | proline rich 5 like | 0.0250919 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0246973 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.024612 |
| FLNB | filamin B, beta | 0.0241378 |
| LATS2 | large tumor suppressor kinase 2 | 0.0241002 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0238684 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0237643 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0232222 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0231979 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0231628 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0229432 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0228729 |
| DUSP5 | dual specificity phosphatase 5 | 0.0227561 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0226191 |
| YAP1 | Yes-associated protein 1 | 0.0225889 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0223906 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0223783 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0220645 |
| MYOF | myoferlin | 0.0214442 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0213142 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.264632 |
| RPS6 | ribosomal protein S6 | -0.132464 |
| FTL | ferritin, light polypeptide | -0.125848 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.123855 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.104172 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101436 |
| FRY | furry homolog (Drosophila) | -0.0946845 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0919863 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0799944 |
| TXNRD1 | thioredoxin reductase 1 | -0.0754148 |
| TMSB10 | thymosin beta 10 | -0.0747073 |
| PTMA | prothymosin, alpha | -0.0707348 |
| RPL35A | ribosomal protein L35a | -0.0664605 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0664407 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.065513 |
| GOLGA4 | golgin A4 | -0.0648042 |
| AGR2 | anterior gradient 2 | -0.061878 |
| LYZ | lysozyme | -0.0609546 |
| RPL34 | ribosomal protein L34 | -0.0605128 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0603718 |
| HM13 | histocompatibility (minor) 13 | -0.0561473 |
| EGR1 | early growth response 1 | -0.0543243 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.051732 |
| RPS19 | ribosomal protein S19 | -0.049428 |
| RPS24 | ribosomal protein S24 | -0.0476103 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0473559 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0461586 |
| RTN3 | reticulon 3 | -0.0459981 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0454252 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0448435 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0439702 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0420898 |
| RRBP1 | ribosome binding protein 1 | -0.0408672 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.039992 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.039441 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0394159 |
| ZNF292 | zinc finger protein 292 | -0.0383401 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0383179 |
| WDR45B | WD repeat domain 45B | -0.0380893 |
| ACTG1 | actin gamma 1 | -0.037681 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.037057 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0369477 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0362726 |
| RPS21 | ribosomal protein S21 | -0.0360179 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0353603 |
| MORF4L2 | mortality factor 4 like 2 | -0.0350936 |
| TMEM65 | transmembrane protein 65 | -0.0350843 |
| RPL12 | ribosomal protein L12 | -0.0348407 |
| EXPH5 | exophilin 5 | -0.0344204 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0338328 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0337419 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0336458 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0335305 |
| GOLGB1 | golgin B1 | -0.0334346 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0333722 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0331462 |
| NF1 | neurofibromin 1 | -0.0324112 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322149 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0319203 |
| LDHA | lactate dehydrogenase A | -0.0318906 |
| HDLBP | high density lipoprotein binding protein | -0.0317019 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0308217 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0306516 |
| DIAPH2 | diaphanous-related formin 2 | -0.0300359 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0295056 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0292586 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0289299 |
| RPL4 | ribosomal protein L4 | -0.0287599 |
| GNAS | GNAS complex locus | -0.0285461 |
| ARF1 | ADP-ribosylation factor 1 | -0.0285063 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0284198 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0282552 |
| RPL26 | ribosomal protein L26 | -0.0281701 |
| KRT8 | keratin 8, type II | -0.0281662 |
| CD2AP | CD2-associated protein | -0.0272218 |
| PGK1 | phosphoglycerate kinase 1 | -0.0271986 |
| RPS13 | ribosomal protein S13 | -0.0270328 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0268725 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0267851 |
| RPS23 | ribosomal protein S23 | -0.0265273 |
| RPL37 | ribosomal protein L37 | -0.0264108 |
| SQSTM1 | sequestosome 1 | -0.0262686 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0262195 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0261907 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0259604 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0254872 |
| ASTN2 | astrotactin 2 | -0.0254709 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0254628 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0251705 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0251431 |
| HMGA1 | high mobility group AT-hook 1 | -0.0250498 |
| RPL23 | ribosomal protein L23 | -0.0244926 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244594 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0243147 |
| KPNB1 | karyopherin (importin) beta 1 | -0.024188 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0240316 |
| RPS8 | ribosomal protein S8 | -0.0239028 |
| CANX | calnexin | -0.0233916 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0233664 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0233662 |
