| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.271956 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.199011 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.155966 |
| MYO1E | myosin IE | 0.142916 |
| FAT1 | FAT atypical cadherin 1 | 0.118575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.113728 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.103145 |
| PTMA | prothymosin, alpha | 0.0967835 |
| VCL | vinculin | 0.0961641 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0878296 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0870354 |
| TPM4 | tropomyosin 4 | 0.0862595 |
| LMO7 | LIM domain 7 | 0.084267 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0695366 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0674342 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0627436 |
| KRT18 | keratin 18, type I | 0.0576754 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0541926 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0517589 |
| GPHN | gephyrin | 0.0504876 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0495048 |
| TPM1 | tropomyosin 1 (alpha) | 0.048305 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0479492 |
| MUC13 | mucin 13, cell surface associated | 0.0450375 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0441887 |
| CD44 | CD44 molecule (Indian blood group) | 0.0436303 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0433592 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0404975 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0404223 |
| CTBP2 | C-terminal binding protein 2 | 0.0403852 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0393503 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0378417 |
| FHL2 | four and a half LIM domains 2 | 0.0375594 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0366282 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0352063 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0348797 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0348774 |
| RIGI | RNA sensor RIG-I | 0.0340127 |
| CANX | calnexin | 0.0333158 |
| TUFT1 | tuftelin 1 | 0.03202 |
| EREG | epiregulin | 0.0318696 |
| RPLP0 | ribosomal protein, large, P0 | 0.0318596 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0313499 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0309902 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0308799 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0307366 |
| ITGA6 | integrin, alpha 6 | 0.0306917 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0303969 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0301917 |
| TRIM2 | tripartite motif containing 2 | 0.0290192 |
| RPS8 | ribosomal protein S8 | 0.0288279 |
| AREG | amphiregulin | 0.0287624 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0287105 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0286955 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0285678 |
| CUX1 | cut-like homeobox 1 | 0.0283628 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0283242 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0279784 |
| PALLD | palladin, cytoskeletal associated protein | 0.0278723 |
| SMYD3 | SET and MYND domain containing 3 | 0.0277452 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0275153 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0271073 |
| ASB4 | ankyrin repeat and SOCS box containing 4 | 0.0269528 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0266786 |
| RPL7 | ribosomal protein L7 | 0.0264988 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.026469 |
| ADIPOR2 | adiponectin receptor 2 | 0.026053 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0256054 |
| FOXP1 | forkhead box P1 | 0.0255107 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0253332 |
| ANXA2 | annexin A2 | 0.0250096 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247838 |
| PKP2 | plakophilin 2 | 0.0247651 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0246036 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.024602 |
| DSTN | destrin (actin depolymerizing factor) | 0.0244406 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0236035 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0233663 |
| CD9 | CD9 molecule | 0.0233035 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0232659 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0232584 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0231762 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0231299 |
| PDE10A | phosphodiesterase 10A | 0.0231194 |
| ECT2 | epithelial cell transforming 2 | 0.0231042 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.022901 |
| TFF1 | trefoil factor 1 | 0.0227201 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0226175 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0222728 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0222207 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0221497 |
| ABR | active BCR-related | 0.0220784 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0218356 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0215598 |
| ENO1 | enolase 1, (alpha) | 0.0214971 |
| SMAD2 | SMAD family member 2 | 0.0213252 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | 0.0211358 |
| FOXO1 | forkhead box O1 | 0.0208844 |
| MAP7 | microtubule-associated protein 7 | 0.0207933 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0207071 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.192952 |
| NDRG1 | N-myc downstream regulated 1 | -0.103775 |
| TMSB10 | thymosin beta 10 | -0.0799557 |
| FLNB | filamin B, beta | -0.0744319 |
| PRELID2 | PRELI domain containing 2 | -0.0629597 |
| RPS6 | ribosomal protein S6 | -0.056131 |
| AHNAK | AHNAK nucleoprotein | -0.0556512 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.052637 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0496327 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0494788 |
| GOLGA4 | golgin A4 | -0.0485462 |
| CALB1 | calbindin 1, 28kDa | -0.0478929 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0467888 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.045755 |
| ITGB4 | integrin, beta 4 | -0.042829 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0428192 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0411478 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0395112 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0381832 |
| PKM | pyruvate kinase, muscle | -0.0365277 |
| ZNF292 | zinc finger protein 292 | -0.0364956 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0353343 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.035042 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0348296 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0347787 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0333523 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0332801 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.033244 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0325299 |
| FAM13A | family with sequence similarity 13, member A | -0.0324286 |
| RIN2 | Ras and Rab interactor 2 | -0.0322794 |
| SBF2 | SET binding factor 2 | -0.0321209 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0314194 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0313566 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0309578 |
| TBC1D22A | TBC1 domain family, member 22A | -0.030861 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0294492 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.029243 |
| DENND1A | DENN/MADD domain containing 1A | -0.0289542 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0288837 |
| PTEN | phosphatase and tensin homolog | -0.0280759 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0280742 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0279275 |
| ONECUT3 | one cut homeobox 3 | -0.0277645 |
| RPL36 | ribosomal protein L36 | -0.0276928 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0275658 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0272452 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0267815 |
| NBEAL1 | neurobeachin-like 1 | -0.026633 |
| KRT8 | keratin 8, type II | -0.0262345 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0259774 |
| RBM39 | RNA binding motif protein 39 | -0.0256312 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0254073 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0254069 |
| NKTR | natural killer cell triggering receptor | -0.0253441 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0250847 |
| CCNY | cyclin Y | -0.0246924 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0242744 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0239325 |
| FNIP1 | folliculin interacting protein 1 | -0.023656 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0236486 |
| CLDN7 | claudin 7 | -0.0236081 |
| NBAS | neuroblastoma amplified sequence | -0.022939 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.022894 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0228791 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0228178 |
| RFX7 | regulatory factor X, 7 | -0.0224941 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0214364 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0214075 |
| RAB6A | RAB6A, member RAS oncogene family | -0.021344 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0212373 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0212348 |
| PLEC | plectin | -0.021098 |
| FNBP1L | formin binding protein 1-like | -0.0210411 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0209717 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0209246 |
| AHR | aryl hydrocarbon receptor | -0.0207648 |
| METTL15 | methyltransferase like 15 | -0.02023 |
| POTEF | POTE ankyrin domain family, member F | -0.0201908 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0201423 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0200827 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0199226 |
| HMBOX1 | homeobox containing 1 | -0.0198796 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0198732 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.019539 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0195066 |
| CDK19 | cyclin-dependent kinase 19 | -0.0194343 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0191731 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0191513 |
| MUC17 | mucin 17, cell surface associated | -0.0191455 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0188265 |
| MAP4 | microtubule-associated protein 4 | -0.0188052 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0187364 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0184523 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.0184315 |
| VEGFA | vascular endothelial growth factor A | -0.0183633 |
| MT2A | metallothionein 2A | -0.0182645 |
| KRT19 | keratin 19, type I | -0.0177624 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0177048 |
| GPR39 | G protein-coupled receptor 39 | -0.0176451 |
