| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.165894 |
| FAT1 | FAT atypical cadherin 1 | 0.126128 |
| RPS2 | ribosomal protein S2 | 0.0957907 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0767772 |
| AREG | amphiregulin | 0.0710551 |
| MT2A | metallothionein 2A | 0.0692706 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0681213 |
| LOC105378220 | macrophage receptor MARCO-like | 0.06721 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0648061 |
| MYO1E | myosin IE | 0.0633205 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0622288 |
| CLDN4 | claudin 4 | 0.0615825 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0594798 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0584341 |
| MUC13 | mucin 13, cell surface associated | 0.0583199 |
| ITGA6 | integrin, alpha 6 | 0.0548304 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0526658 |
| RPS29 | ribosomal protein S29 | 0.0505184 |
| RPS12 | ribosomal protein S12 | 0.0501113 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.048232 |
| ANXA2 | annexin A2 | 0.0466158 |
| MX1 | MX dynamin-like GTPase 1 | 0.0452763 |
| RPS3 | ribosomal protein S3 | 0.0447189 |
| ABHD17C | abhydrolase domain containing 17C | 0.0447063 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.044612 |
| RPL36 | ribosomal protein L36 | 0.0431335 |
| RNF145 | ring finger protein 145 | 0.0427521 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0420546 |
| TXNRD1 | thioredoxin reductase 1 | 0.0417447 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0408416 |
| WWOX | WW domain containing oxidoreductase | 0.0405114 |
| SERINC5 | serine incorporator 5 | 0.0400233 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0399409 |
| EMP1 | epithelial membrane protein 1 | 0.0395919 |
| TC2N | tandem C2 domains, nuclear | 0.0381703 |
| PCBP2 | poly(rC) binding protein 2 | 0.0379347 |
| SQSTM1 | sequestosome 1 | 0.0375784 |
| S100P | S100 calcium binding protein P | 0.0375068 |
| ENO1 | enolase 1, (alpha) | 0.0366195 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0365325 |
| RPL9 | ribosomal protein L9 | 0.0350999 |
| RPL7 | ribosomal protein L7 | 0.034992 |
| FOXO1 | forkhead box O1 | 0.0346638 |
| RPL13A | ribosomal protein L13a | 0.0345034 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0343296 |
| B2M | beta-2-microglobulin | 0.0331983 |
| EREG | epiregulin | 0.0326486 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0323269 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0312183 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0305908 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.030493 |
| MED13L | mediator complex subunit 13-like | 0.0303162 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0299476 |
| RPS13 | ribosomal protein S13 | 0.0298882 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0298819 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.02965 |
| SLTM | SAFB-like, transcription modulator | 0.0288055 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0287689 |
| RACK1 | receptor for activated C kinase 1 | 0.0284949 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0282137 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0279868 |
| AUTS2 | autism susceptibility candidate 2 | 0.0278451 |
| OXSR1 | oxidative stress responsive 1 | 0.0277937 |
| PKP2 | plakophilin 2 | 0.0274972 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0274439 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0266858 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0266716 |
| FOXP1 | forkhead box P1 | 0.0265333 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0263548 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261175 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0260984 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0260369 |
| PKM | pyruvate kinase, muscle | 0.0259312 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0254062 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0248976 |
| EXOC6B | exocyst complex component 6B | 0.0248199 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0245806 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0242939 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0241568 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0240426 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0238511 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0236714 |
| RPS23 | ribosomal protein S23 | 0.0235246 |
| MT1E | metallothionein 1E | 0.0233295 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0233183 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0229135 |
| PTK2 | protein tyrosine kinase 2 | 0.022629 |
| EFNB2 | ephrin-B2 | 0.0222904 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0222149 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0220606 |
| TPI1 | triosephosphate isomerase 1 | 0.0220297 |
| RAD51B | RAD51 paralog B | 0.0218064 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0217033 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0215873 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0215242 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0215187 |
| PDZD8 | PDZ domain containing 8 | 0.0215075 |
| RPS27 | ribosomal protein S27 | 0.021412 |
| ATXN1 | ataxin 1 | 0.020834 |
| NEBL | nebulette | 0.0207942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.221752 |
| RPS6 | ribosomal protein S6 | -0.186458 |
| TMSB10 | thymosin beta 10 | -0.150706 |
| RPL35A | ribosomal protein L35a | -0.142456 |
| RPL34 | ribosomal protein L34 | -0.123603 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.113806 |
| RPS19 | ribosomal protein S19 | -0.0830235 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0827053 |
| FLNB | filamin B, beta | -0.0771236 |
| RPS24 | ribosomal protein S24 | -0.0760744 |
| LMO7 | LIM domain 7 | -0.0706719 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0702623 |
| PTMA | prothymosin, alpha | -0.0671495 |
| RPL4 | ribosomal protein L4 | -0.0610927 |
| KRT8 | keratin 8, type II | -0.0600927 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0573361 |
| GOLGA4 | golgin A4 | -0.0568188 |
| RPS21 | ribosomal protein S21 | -0.0533402 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0532347 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.051303 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0509749 |
| DSPP | dentin sialophosphoprotein | -0.0508787 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0501947 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0498876 |
| S100A6 | S100 calcium binding protein A6 | -0.048617 |
| DSG2 | desmoglein 2 | -0.0482613 |
| RRBP1 | ribosome binding protein 1 | -0.0466305 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0461044 |
| TSPAN8 | tetraspanin 8 | -0.0458216 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0453862 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0449705 |
| NPSR1 | neuropeptide S receptor 1 | -0.0431641 |
| RPL31 | ribosomal protein L31 | -0.0405226 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0394031 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0392766 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0384844 |
| RBM25 | RNA binding motif protein 25 | -0.0377253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0376169 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0367099 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0366118 |
| RPL14 | ribosomal protein L14 | -0.0357095 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0356796 |
| MCU | mitochondrial calcium uniporter | -0.0343368 |
| GOLGB1 | golgin B1 | -0.0341696 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0338934 |
| EZR | ezrin | -0.0337613 |
| RPS14 | ribosomal protein S14 | -0.0336779 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.033223 |
| CALU | calumenin | -0.0332037 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0326231 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.0313362 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0313181 |
| RPL11 | ribosomal protein L11 | -0.0298691 |
| AHNAK | AHNAK nucleoprotein | -0.0297441 |
| PERP | PERP, TP53 apoptosis effector | -0.0292844 |
| AGR2 | anterior gradient 2 | -0.0292306 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0291508 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.028969 |
| INHBA | inhibin, beta A | -0.0288396 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.028819 |
| HDLBP | high density lipoprotein binding protein | -0.0287839 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.028547 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0282586 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0281882 |
| ACTN4 | actinin, alpha 4 | -0.0279361 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0275628 |
| COG5 | component of oligomeric golgi complex 5 | -0.0275195 |
| TMF1 | TATA element modulatory factor 1 | -0.0273906 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.02731 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.0272531 |
| MYO6 | myosin VI | -0.0272133 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0271799 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.0268694 |
| LAMB3 | laminin, beta 3 | -0.0267809 |
| CDK12 | cyclin-dependent kinase 12 | -0.0267325 |
| GNAS | GNAS complex locus | -0.0265456 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0263823 |
| NPR2 | natriuretic peptide receptor 2 | -0.0263393 |
| SCFD1 | sec1 family domain containing 1 | -0.0259441 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0259101 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0254946 |
| RPL23 | ribosomal protein L23 | -0.0253774 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0251989 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0250736 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.025043 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0249596 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0248813 |
| HMGA1 | high mobility group AT-hook 1 | -0.0247355 |
| ACTG1 | actin gamma 1 | -0.0245598 |
| SEC24D | SEC24 family member D | -0.0245334 |
| RPL3 | ribosomal protein L3 | -0.0244702 |
| FNIP1 | folliculin interacting protein 1 | -0.0243255 |
| TMEM165 | transmembrane protein 165 | -0.0242398 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0239939 |
| RHOA | ras homolog family member A | -0.0239802 |
| CLINT1 | clathrin interactor 1 | -0.0239769 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0239693 |
| TMEM263 | transmembrane protein 263 | -0.023884 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0238345 |
| RPL36A | ribosomal protein L36a | -0.0238216 |
