| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Palmatine (chloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.221378 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.195728 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.193678 |
| FTL | ferritin, light polypeptide | 0.167173 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.131836 |
| MCL1 | myeloid cell leukemia 1 | 0.102935 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0970841 |
| GRAMD1B | GRAM domain containing 1B | 0.0933965 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0827199 |
| WWOX | WW domain containing oxidoreductase | 0.0759682 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0744858 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0733877 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0635809 |
| RPLP1 | ribosomal protein, large, P1 | 0.0626429 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0589999 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0580375 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0524886 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0520167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0495452 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0493863 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0461099 |
| RPL19 | ribosomal protein L19 | 0.0452374 |
| ASPH | aspartate beta-hydroxylase | 0.0446439 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0439659 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0432298 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0427238 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0413701 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0378683 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0377095 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0376159 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0374361 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0372688 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0369418 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0360995 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0358323 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0352263 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.034943 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0347803 |
| RPL23 | ribosomal protein L23 | 0.0336651 |
| FAM107B | family with sequence similarity 107, member B | 0.0320799 |
| YBX1 | Y box binding protein 1 | 0.0319783 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0312094 |
| RPS2 | ribosomal protein S2 | 0.0308211 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.030802 |
| BMP6 | bone morphogenetic protein 6 | 0.0307469 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0305713 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.030516 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0305106 |
| DOCK5 | dedicator of cytokinesis 5 | 0.030047 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0299918 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0298866 |
| FGB | fibrinogen beta chain | 0.0293416 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0290338 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0285 |
| FLNA | filamin A, alpha | 0.0282972 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0282819 |
| BRD2 | bromodomain containing 2 | 0.0282327 |
| ATXN1 | ataxin 1 | 0.0278824 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0273462 |
| PCBP2 | poly(rC) binding protein 2 | 0.0269015 |
| ANXA2 | annexin A2 | 0.0265736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0263135 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0262017 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.025744 |
| TPM3 | tropomyosin 3 | 0.0257052 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0256808 |
| ACTN1 | actinin, alpha 1 | 0.0252396 |
| FHIT | fragile histidine triad | 0.0252385 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0252296 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0249171 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.024451 |
| PDE10A | phosphodiesterase 10A | 0.0238937 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.023716 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0236979 |
| NTN4 | netrin 4 | 0.0236757 |
| RPS20 | ribosomal protein S20 | 0.0233381 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0233117 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0232683 |
| RPLP0 | ribosomal protein, large, P0 | 0.0232071 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0228441 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0227619 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0225956 |
| MYOF | myoferlin | 0.0224849 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223902 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0220842 |
| FUS | FUS RNA binding protein | 0.0218427 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.021838 |
| RPS19 | ribosomal protein S19 | 0.021557 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0213236 |
| RTN4 | reticulon 4 | 0.0211402 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0210777 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.020998 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0206375 |
| DST | dystonin | 0.0205792 |
| JAK1 | Janus kinase 1 | 0.0202422 |
| CANX | calnexin | 0.0201676 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0201371 |
| HYOU1 | hypoxia up-regulated 1 | 0.0199986 |
| RPS8 | ribosomal protein S8 | 0.0199985 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0199631 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.106229 |
| VIM | vimentin | -0.100755 |
| TXNRD1 | thioredoxin reductase 1 | -0.0689732 |
| HDAC9 | histone deacetylase 9 | -0.0611866 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0577834 |
| ERBIN | erbb2 interacting protein | -0.0549886 |
| TMSB10 | thymosin beta 10 | -0.0534889 |
| ACTG1 | actin gamma 1 | -0.0474785 |
| PTMA | prothymosin, alpha | -0.041333 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0396744 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0371131 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0370597 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.03312 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.031418 |
| WDR43 | WD repeat domain 43 | -0.0310684 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0308523 |
| AK1 | adenylate kinase 1 | -0.0289906 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0287973 |
| MT2A | metallothionein 2A | -0.0286213 |
| GLG1 | golgi glycoprotein 1 | -0.0286096 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0285641 |
| THBS1 | thrombospondin 1 | -0.0283434 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0257641 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0253877 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0239449 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0235415 |
| RPS21 | ribosomal protein S21 | -0.0225507 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0222978 |
| IER3 | immediate early response 3 | -0.0222951 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0222826 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0219433 |
| RBM25 | RNA binding motif protein 25 | -0.0214476 |
| EGFR | epidermal growth factor receptor | -0.0206678 |
| ECT2 | epithelial cell transforming 2 | -0.020206 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0201251 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0196018 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0191955 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0191654 |
| KLF6 | Kruppel-like factor 6 | -0.0191425 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0188918 |
| SRGN | serglycin | -0.0188163 |
| RASAL2 | RAS protein activator like 2 | -0.0184876 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0184347 |
| YME1L1 | YME1-like 1 ATPase | -0.0184122 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0182949 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0182693 |
| PHF20 | PHD finger protein 20 | -0.0181291 |
| RPS24 | ribosomal protein S24 | -0.0178207 |
| USP34 | ubiquitin specific peptidase 34 | -0.0169819 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0169143 |
| NOL10 | nucleolar protein 10 | -0.0167375 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0166641 |
| CFDP1 | craniofacial development protein 1 | -0.0164805 |
| YY1 | YY1 transcription factor | -0.0163402 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0162259 |
| HMGA1 | high mobility group AT-hook 1 | -0.0160875 |
| TES | testin LIM domain protein | -0.0159223 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0157415 |
| RPS13 | ribosomal protein S13 | -0.0155664 |
| PRR16 | proline rich 16 | -0.0153907 |
| TPD52 | tumor protein D52 | -0.0152944 |
| CENPF | centromere protein F, 350/400kDa | -0.0152563 |
| RHOA | ras homolog family member A | -0.0151677 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0150872 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0150837 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.014991 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | -0.0148581 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0147833 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0146288 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0142847 |
| TMEM123 | transmembrane protein 123 | -0.0142731 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0140037 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0139088 |
| CAVIN1 | caveolae associated protein 1 | -0.0138531 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0138416 |
| COG5 | component of oligomeric golgi complex 5 | -0.0138013 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0137816 |
| NEBL | nebulette | -0.0137136 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0136477 |
| NDRG1 | N-myc downstream regulated 1 | -0.0135904 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.013466 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0133803 |
| CFAP73 | cilia and flagella associated protein 73 | -0.0133432 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0132649 |
| OSBP | oxysterol binding protein | -0.0132296 |
| RBM8A | RNA binding motif protein 8A | -0.0131938 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0131239 |
| FRMD4A | FERM domain containing 4A | -0.0131198 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0129258 |
| ILF2 | interleukin enhancer binding factor 2 | -0.0128337 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0128272 |
| TMEM87A | transmembrane protein 87A | -0.0127675 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | -0.0126609 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0126224 |
| MORF4L1 | mortality factor 4 like 1 | -0.0125757 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0124855 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0124115 |
| FMNL2 | formin-like 2 | -0.0123303 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0123211 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0123186 |
