| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Palmatine (chloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Palmatine (chloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | 0.210431 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.139202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.108932 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.100344 |
| FN1 | fibronectin 1 | 0.0931662 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0890954 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0886172 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0883642 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0867424 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0835873 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.081189 |
| TXNRD1 | thioredoxin reductase 1 | 0.0783476 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0778438 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0770569 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0755598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0712583 |
| VIM | vimentin | 0.0708833 |
| EZR | ezrin | 0.0699019 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0669194 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0669099 |
| DSPP | dentin sialophosphoprotein | 0.0664245 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0653253 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0650823 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0630748 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0615377 |
| CUX1 | cut-like homeobox 1 | 0.060736 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0605252 |
| SQSTM1 | sequestosome 1 | 0.0602274 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0600761 |
| MYO10 | myosin X | 0.0599908 |
| ATXN1 | ataxin 1 | 0.0589012 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0585212 |
| ACTG1 | actin gamma 1 | 0.0576568 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0568375 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0551829 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0545668 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0534529 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.052992 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0529797 |
| TOP1 | topoisomerase (DNA) I | 0.0519673 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0517986 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0514624 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0513826 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0511018 |
| RUNX1 | runt-related transcription factor 1 | 0.0510678 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.050457 |
| RND3 | Rho family GTPase 3 | 0.0487284 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | 0.0485899 |
| VCL | vinculin | 0.0482675 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0481976 |
| VMP1 | vacuole membrane protein 1 | 0.0478276 |
| MYO1E | myosin IE | 0.0474034 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0470988 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0469027 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0463423 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.046136 |
| PRKCA | protein kinase C, alpha | 0.0460458 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0455159 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0452498 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0451922 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0448305 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.044151 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.043323 |
| KYNU | kynureninase | 0.0429538 |
| GPC6 | glypican 6 | 0.0429481 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0428458 |
| TENM3 | teneurin transmembrane protein 3 | 0.0419053 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0417319 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0416603 |
| MT2A | metallothionein 2A | 0.0414926 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0413574 |
| INTS6 | integrator complex subunit 6 | 0.0405476 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0404732 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0404403 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0404025 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0398344 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0396404 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0395441 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0389993 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0386753 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0379198 |
| DIAPH1 | diaphanous-related formin 1 | 0.0375317 |
| ATP11A | ATPase, class VI, type 11A | 0.0373602 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0372678 |
| FOXO1 | forkhead box O1 | 0.036829 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0365086 |
| SMYD3 | SET and MYND domain containing 3 | 0.0363271 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0363162 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0361581 |
| ENO1 | enolase 1, (alpha) | 0.0359987 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0347257 |
| AHNAK | AHNAK nucleoprotein | 0.0345424 |
| IGF2 | insulin-like growth factor 2 | 0.0344486 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0343565 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0343547 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0342701 |
| LMO7 | LIM domain 7 | 0.033645 |
| YTHDC1 | YTH domain containing 1 | 0.0333685 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0333202 |
| DST | dystonin | 0.0331103 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.158816 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0895571 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0767708 |
| FTL | ferritin, light polypeptide | -0.0684513 |
| B2M | beta-2-microglobulin | -0.0666557 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0646409 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0635272 |
| TMSB10 | thymosin beta 10 | -0.0632824 |
| ZNF638 | zinc finger protein 638 | -0.0601511 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0571477 |
| DTNA | dystrobrevin, alpha | -0.0567435 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0535328 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0524245 |
| LAMB3 | laminin, beta 3 | -0.0522849 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0522688 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0520235 |
| KIF13B | kinesin family member 13B | -0.0508815 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0505864 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0505368 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0504381 |
| ATOSA | atos homolog A | -0.049918 |
| RBM47 | RNA binding motif protein 47 | -0.0490489 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0484638 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0479753 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0479573 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0462247 |
| RPL35A | ribosomal protein L35a | -0.0460908 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.044468 |
| SETD5 | SET domain containing 5 | -0.0442516 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0436186 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0427039 |
| MUC16 | mucin 16, cell surface associated | -0.0426822 |
| GLCCI1 | glucocorticoid induced 1 | -0.0425969 |
| RIGI | RNA sensor RIG-I | -0.0420808 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0420069 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0419526 |
| S100A11 | S100 calcium binding protein A11 | -0.0419031 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0415536 |
| LSAMP | limbic system-associated membrane protein | -0.0412736 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0399424 |
| TMEM165 | transmembrane protein 165 | -0.0396541 |
| PMM2 | phosphomannomutase 2 | -0.0390374 |
| EGR1 | early growth response 1 | -0.0389686 |
| RAB6A | RAB6A, member RAS oncogene family | -0.038846 |
| SSH2 | slingshot protein phosphatase 2 | -0.0388009 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0386794 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0386743 |
| CLDN7 | claudin 7 | -0.0386361 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0382235 |
| YME1L1 | YME1-like 1 ATPase | -0.0379583 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0375731 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0370842 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0370277 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0369826 |
| RPS17 | ribosomal protein S17 | -0.0364621 |
| RORA | RAR-related orphan receptor A | -0.0363977 |
| NEMF | nuclear export mediator factor | -0.0359097 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0358131 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0356412 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0355996 |
| RPL26 | ribosomal protein L26 | -0.0355266 |
| GOLM2 | golgi membrane protein 2 | -0.0353683 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0351789 |
| LASP1 | LIM and SH3 protein 1 | -0.0350947 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0350353 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0349978 |
| EFNA5 | ephrin-A5 | -0.0346957 |
| NBEAL1 | neurobeachin-like 1 | -0.0344914 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0344264 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0342139 |
| ATF6 | activating transcription factor 6 | -0.033905 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0338433 |
| TLK1 | tousled-like kinase 1 | -0.033626 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0334499 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0334324 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0331804 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0329264 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0328482 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0328041 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0325201 |
| RPL32 | ribosomal protein L32 | -0.0321734 |
| SLK | STE20-like kinase | -0.0320651 |
| FMN1 | formin 1 | -0.0319271 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0318445 |
| S100A9 | S100 calcium binding protein A9 | -0.0318311 |
| SCEL | sciellin | -0.0318135 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.031812 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0317578 |
| OXSR1 | oxidative stress responsive 1 | -0.0317312 |
| SH3D19 | SH3 domain containing 19 | -0.0316071 |
| PDE8A | phosphodiesterase 8A | -0.0313895 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0313827 |
| REPS1 | RALBP1 associated Eps domain containing 1 | -0.0312989 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0312686 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0309482 |
| PTEN | phosphatase and tensin homolog | -0.0307489 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0307411 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0306844 |
| RIOK3 | RIO kinase 3 | -0.0304051 |
| ATP13A3 | ATPase type 13A3 | -0.0303443 |
